論文・総説 - 細谷　孝充

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  1. Inouye S, Sato J, Sahara-Miura Y, Yoshida S, Hosoya T. Luminescence enhancement of the catalytic 19kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions. Biochem Biophys Res Commun. 2014.02; 445 (1): 157-162. ( PubMed, DOI )

  2. Sumi K, Inoue Y, Nishio M, Naito Y, Hosoya T, Suzuki M, Hidaka H. IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys. Bioorg Med Chem Lett. 2014.02; 24 (3): 831-834. ( PubMed, DOI )

  3. Yoshida S, Uchida K, Hosoya T. Generation of arynes triggered by sulfoxide-metal exchange reaction of ortho-sulfinylaryl triflates. Chem Lett. 2014; 43 (1): 116-118. ( DOI )

  4. Tanaka K, Nakamoto Y, Siwu ER, Pradipta AR, Morimoto K, Fujiwara T, Yoshida S, Hosoya T, Tamura Y, Hirai G, Sodeoka M, Fukase K. Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation. Org Biomol Chem. 2013.11; 11 (42): 7326-7333. ( PubMed, DOI )

  5. Miyajima M, Kusuhara H, Takahashi K, Takashima T, Hosoya T, Watanabe Y, Sugiyama Y. Investigation of the effect of active efflux at the blood-brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system. J Pharm Sci. 2013.09; 102 (9): 3309-3319. ( PubMed, DOI )

  6. Inouye S, Sato J, Sahara-Miura Y, Yoshida S, Kurakata H, Hosoya T. C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase. Biochem Biophys Res Commun. 2013.07; 437 (1): 23-28. ( PubMed, DOI )

  7. Sumida Y, Kato T, Hosoya T. Generation of arynes via ate complexes of arylboronic esters with an ortho-leaving group. Org Lett. 2013.06; 15 (11): 2806-2809. ( PubMed, DOI )

  8. Inouye S, Sahara-Miura Y, Sato J, Iimori R, Yoshida S, Hosoya T. Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines. Protein Expr Purif. 2013.03; 88 (1): 150-156. ( PubMed, DOI )

  9. Koyama H, Zhang Z, Ijuin R, Siqin, Son J, Hatta Y, Ohta M, Wakao M, Hosoya T, Doi H, Suzuki M.. Pd(0)-mediated rapid coupling of methyl iodide with excess amounts of benzyl- and cinnamylboronic acid esters: efficient method for incorporation of positron-emitting (11)C radionuclide into organic frameworks by coupling between two sp(3)-hybridized carbons. RSC Adv. 2013; 3 (24): 9391-9401. ( DOI )

  10. Yoshida S, Hosoya T. Synthesis of diverse aromatic oxophosphorus compounds by the Michaelis-Arbuzov-type reaction of arynes. Chem Lett. 2013; 42 (6): 583-585. ( DOI )

  11. Yoshimura SH, Khan S, Ohno S, Yokogawa T, Nishikawa K, Hosoya T, Maruyama H, Nakayama Y, Takeyasu K. Site-specific attachment of a protein to a carbon nanotube end without loss of protein function. Bioconjug Chem. 2012.07; 23 (7): 1488-1493. ( PubMed, DOI )

  12. Sumida Y, Kato T, Yoshida S, Hosoya T. Palladium-catalyzed regio- and stereoselective hydrosilylation of electron-deficient alkynes. Org Lett. 2012.03; 14 (6): 1552-1555. ( PubMed, DOI )

  13. Ozawa M, Takahashi K, Akazawa KH, Takashima T, Nagata H, Doi H, Hosoya T, Wada Y, Cui Y, Kataoka Y, Watanabe Y. PET of aromatase in gastric parietal cells using 11C-vorozole. J Nucl Med. 2011.12; 52 (12): 1964-1969. ( PubMed, DOI )

  14. Takahashi K, Onoe K, Doi H, Nagata H, Yamagishi G, Hosoya T, Tamura Y, Wada Y, Yamanaka H, Yokoyama C, Mizuma H, Takashima T, Bergström M, Onoe H, Långström B, Watanabe Y. Increase in hypothalamic aromatase in macaque monkeys treated with anabolic-androgenic steroids: PET study with [11C]vorozole. NeuroReport. 2011.05; 22 (7): 326-330. ( PubMed, DOI )

  15. Takahashi K, Yamagishi G, Hiramatsu T, Hosoya A, Onoe K, Doi H, Nagata H, Wada Y, Onoe H, Watanabe Y, Hosoya T. Practical synthesis of precursor of [N-methyl-11C]vorozole, an efficient PET tracer targeting aromatase in the brain. Bioorg Med Chem. 2011.02; 19 (4): 1464-1470. ( PubMed, DOI )

  16. Sakai D, Kii I, Nakagawa K, Matsumoto HN, Takahashi M, Yoshida S, Hosoya T, Takakuda K, Kudo A. Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation. PLoS ONE. 2011; 6 (9): e24847. ( PubMed, DOI )

  17. Islam MS, Nagasaka R, Ohara K, Hosoya T, Ozaki H, Ushio H, Hori M. Biological abilities of rice bran-derived antioxidant phytochemicals for medical therapy. Curr Top Med Chem. 2011; 11 (14): 1847-1853. ( PubMed )

  18. Yoshida S, Shiraishi A, Kanno K, Matsushita T, Johmoto K, Uekusa H, Hosoya T. Enhanced clickability of doubly sterically-hindered aryl azides. Sci Rep. 2011; 1 82. ( PubMed, DOI )

  19. Anwar A, Hosoya T, Leong KM, Onogi H, Okuno Y, Hiramatsu T, Koyama H, Suzuki M, Hagiwara M, Garcia-Blanco MA. The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly. PLoS ONE. 2011; 6 (8): e23246. ( PubMed, DOI )

  20. Inouye S, Iimori R, Sahara Y, Hisada S, Hosoya T. Application of new semisynthetic aequorins with long half-decay time of luminescence to G-protein-coupled receptor assay. Anal Biochem. 2010.12; 407 (2): 247-252. ( PubMed, DOI )

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