論文・総説 - 細谷 孝充
-
Abe Y, Okumura E, Hosoya T, Hirota T, Kishimoto T. A single starfish Aurora kinase performs the combined functions of Aurora-A and Aurora-B in human cells. J Cell Sci. 2010.11; 123 (Pt 22): 3978-3988. ( PubMed, DOI )
-
Ogawa Y, Nonaka Y, Goto T, Ohnishi E, Hiramatsu T, Kii I, Yoshida M, Ikura T, Onogi H, Shibuya H, Hosoya T, Ito N, Hagiwara M. Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. Nat Commun. 2010.10; 1 (7): 86. ( PubMed, DOI )
-
Kii I, Shiraishi A, Hiramatsu T, Matsushita T, Uekusa H, Yoshida S, Yamamoto M, Kudo A, Hagiwara M, Hosoya T. Strain-promoted double-click reaction for chemical modification of azido-biomolecules. Org Biomol Chem. 2010.09; 8 (18): 4051-4055. ( PubMed, DOI )
-
Kohta R, Kotake Y, Hosoya T, Hiramatsu T, Otsubo Y, Koyama H, Hirokane Y, Yokoyama Y, Ikeshoji H, Oofusa K, Suzuki M, Ohta S. 1-Benzyl-1,2,3,4-tetrahydroisoquinoline binds with tubulin beta, a substrate of parkin, and reduces its polyubiquitination. J Neurochem. 2010.09; 114 (5): 1291-1301. ( PubMed, DOI )
-
Ikemoto T, Hosoya T, Takata K, Aoyama H, Hiramatsu T, Onoe H, Suzuki M, Endo M. Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4. Diabetes. 2009.12; 58 (12): 2802-2812. ( PubMed, DOI )
-
Islam MS, Yoshida H, Matsuki N, Ono K, Nagasaka R, Ushio H, Guo Y, Hiramatsu T, Hosoya T, Murata T, Hori M, Ozaki H. Antioxidant, free radical-scavenging, and NF-kappaB-inhibitory activities of phytosteryl ferulates: structure-activity studies. J Pharmacol Sci. 2009.12; 111 (4): 328-337. ( PubMed )
-
Suzuki M, Sumi K, Koyama H, Siqin, Hosoya T, Takashima-Hirano M, Doi H. Pd(0)-Mediated rapid coupling between methyl iodide and heteroarylstannanes: an efficient and general method for the incorporation of a positron-emitting (11)C radionuclide into heteroaromatic frameworks. Chem Eur J. 2009.11; 15 (45): 12489-12495. ( PubMed, DOI )
-
Inouye S, Hosoya T. Reconstitution of blue fluorescent protein from recombinant apoaequorin and synthetic coelenteramide. Biochem Biophys Res Commun. 2009.09; 386 (4): 617-622. ( PubMed, DOI )
-
Hosoya T, Inoue A, Hiramatsu T, Aoyama H, Ikemoto T, Suzuki M. Facile synthesis of diazido-functionalized biaryl compounds as radioisotope-free photoaffinity probes by Suzuki-Miyaura coupling. Bioorg Med Chem. 2009.03; 17 (6): 2490-2496. ( PubMed, DOI )
-
Kuramori C, Azuma M, Kume K, Kaneko Y, Inoue A, Yamaguchi Y, Kabe Y, Hosoya T, Kizaki M, Suematsu M, Handa H. Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus. Biochem Biophys Res Commun. 2009.02; 379 (2): 519-525. ( PubMed, DOI )
-
Doi H, Ban I, Nonoyama A, Sumi K, Kuang C, Hosoya T, Tsukada H, Suzuki M. Palladium(0)-mediated rapid methylation and fluoromethylation on carbon frameworks by reacting methyl and fluoromethyl iodide with aryl and alkenyl boronic acid esters: useful for the synthesis of [11C]CH(3)--C- and [18F]FCH2--C-Containing PET tracers (PET=positron emission tomography). Chem Eur J. 2009; 15 (16): 4165-4171. ( PubMed, DOI )
-
Yomoda J, Muraki M, Kataoka N, Hosoya T, Suzuki M, Hagiwara M, Kimura H. Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A. Genes Cells. 2008.03; 13 (3): 233-244. ( PubMed, DOI )
-
Hiramatsu T, Guo Y, Hosoya T. 3-Azidodifluoromethyl-3H-diazirin-3-yl group as an all-in-one functional group for radioisotope-free photoaffinity labeling. Org Biomol Chem. 2007.09; 5 (18): 2916-2919. ( PubMed, DOI )
-
Abe M, Ohno S, Yokogawa T, Nakanishi T, Arisaka F, Hosoya T, Hiramatsu T, Suzuki M, Ogasawara T, Sawasaki T, Nishikawa K, Kitamura M, Hori H, Endo Y. Detection of structural changes in a cofactor binding protein by using a wheat germ cell-free protein synthesis system coupled with unnatural amino acid probing. Proteins. 2007.05; 67 (3): 643-652. ( PubMed, DOI )
-
Ohno S, Matsui M, Yokogawa T, Nakamura M, Hosoya T, Hiramatsu T, Suzuki M, Hayashi N, Nishikawa K. Site-selective post-translational modification of proteins using an unnatural amino acid, 3-azidotyrosine. J Biochem. 2007.03; 141 (3): 335-343. ( PubMed, DOI )
-
Cui Y, Takamatsu H, Kakiuchi T, Ohba H, Kataoka Y, Yokoyama C, Onoe H, Watanabe Y, Hosoya T, Suzuki M, Noyori R, Tsukada H, Watanabe Y. Neuroprotection by a central nervous system-type prostacyclin receptor ligand demonstrated in monkeys subjected to middle cerebral artery occlusion and reperfusion: a positron emission tomography study. Stroke. 2006.11; 37 (11): 2830-2836. ( PubMed, DOI )
-
Fukuhara T, Hosoya T, Shimizu S, Sumi K, Oshiro T, Yoshinaka Y, Suzuki M, Yamamoto N, Herzenberg LA, Herzenberg LA, Hagiwara M. Utilization of host SR protein kinases and RNA-splicing machinery during viral replication. Proc Natl Acad Sci USA. 2006.07; 103 (30): 11329-11333. ( PubMed, DOI )
-
Hosoya T, Sumi K, Doi H, Wakao M, Suzuki M. Rapid methylation on carbon frameworks useful for the synthesis of 11CH3-incorporated PET tracers: Pd(0)-mediated rapid coupling of methyl iodide with an alkenyltributylstannane leading to a 1-methylalkene. Org Biomol Chem. 2006.02; 4 (3): 410-415. ( PubMed, DOI )
-
Hosoya T, Hiramatsu T, Ikemoto T, Aoyama H, Ohmae T, Endo M, Suzuki M. Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca2+ release from sarcoplasmic reticulum of skeletal muscle. Bioorg Med Chem Lett. 2005.03; 15 (5): 1289-1294. ( PubMed, DOI )
-
Suzuki M, Doi H, Kato K, Hosoya T, Watanabe Y, Watanabe Y. Designed molecular probes in brain research: molecular imaging of IP2 receptor in the human brain. Jpn J Neuropsychopharmacol. 2004.08; 24 (4): 221-229. ( PubMed )