論文・総説 - 細谷　孝充

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  1. Meguro T, Chen S, Kanemoto K, Yoshida S, Hosoya T. Modular Synthesis of Unsymmetrical Doubly-ring-fused Benzene Derivatives Based on a Sequential Ring Construction Strategy Using Oxadiazinones as a Platform Molecule. Chem Lett. 2019.06; 48 (6): 582-585. ( DOI )

  2. Watanabe K, Tsuda J, Ochiai H, Niwa T, Hosoya T. Divergent Synthesis of Photoaffinity Probe Candidates by Click Reactions of Azido-Substituted Aryltrifluoromethyldiazirines. Heterocycles. 2019.06; 99 (2): 1366-1387. ( DOI )

  3. Nishiyama Y, Misawa Y, Hazama Y, Oya K, Yoshida S, Hosoya T. Synthesis of Diverse 3-Azido-5-(azidomethyl)benzene Derivatives via Formal C–H Azidation and Functional Group-Selective Transformations. Heterocycles. 2019.06; 99 (2): 1053-1072. ( DOI )

  4. Kanemoto K, Yoshida S, Hosoya T. Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates. Org Lett. 2019.04; 21 (9): 3172-3177. ( PubMed, DOI )

  5. Yoshida S, Kuribara T, Ito H, Meguro T, Nishiyama Y, Karaki F, Hatakeyama Y, Koike Y, Kii I, Hosoya T. A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach. Chem Commun. 2019.03; 55 (24): 3556-3559. ( PubMed, DOI )

  6. Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, Nakane T, Shiimura Y, Nakagita T, Tsuge K, Yoshida S, Kuribara T, Hosoya T, Sugimoto Y, Nomura N, Sato M, Hirokawa T, Kinoshita M, Murata T, Takayama K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T. Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface. Nat Chem Biol. 2019.01; 15 (1): 18-26. ( PubMed, DOI )

  7. Zhang Z, Niwa T, Watanabe Y, Hosoya T. Palladium(II)-mediated rapid 11C-cyanation of (hetero)arylborons. Org Biomol Chem. 2018.11; 16 (41): 7711-7716. ( PubMed, DOI )

  8. Takahashi K, Hosoya T, Onoe K, Takashima T, Tanaka M, Ishii A, Nakatomi Y, Tazawa S, Takahashi K, Doi H, Wada Y, Watanabe Y. Association between aromatase in human brains and personality traits. Sci Rep. 2018.11; 8 (1): 16841. ( PubMed, DOI )

  9. Yoshida S, Tanaka J, Nishiyama Y, Hazama Y, Matsushita T, Hosoya T. Further enhancement of the clickability of doubly sterically-hindered aryl azides by para-amino substitution. Chem Commun. 2018.11; 54 (96): 13499-13502. ( PubMed, DOI )

  10. Sumida Y, Harada R, Sumida T, Hashizume D, Hosoya T. Hydrosilyl Group-directed Iridium-catalyzed peri-Selective C–H Borylation of Ring-fused (Hetero)Arenes. Chem Lett. 2018.10; 47 (10): 1251-1254. ( DOI )

  11. Matsuzawa T, Yoshida S, Hosoya T. Recent advances in reactions between arynes and organosulfur compounds. Tetrahedron Lett. 2018.10; 59 (48): 4197-4208 . ( DOI )

  12. Nishiyama Y, Kamada S, Yoshida S, Hosoya T. Generation of Arynes by Selective Cleavage of a Carbon–Phosphorus Bond of o-(Diarylphosphinyl)aryl Triflates Using a Grignard Reagent. Chem Lett. 2018.09; 47 (9): 1216-1219. ( DOI )

  13. Inouye S, Tomabechi Y, Hosoya T, Sekine S, Shirouzu M. Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin. J Biochem. 2018.09; 164 (3): 247-255. ( PubMed, DOI )

  14. Meguro T, Terashima N, Ito H, Koike Y, Kii I, Yoshida S, Hosoya T. Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells. Chem Commun. 2018.07; 54 (57): 7904-7907. ( PubMed, DOI )

  15. Matsuzawa T, Uchida K, Yoshida S, Hosoya T. Synthesis of Diverse Phenothiazines by Direct Thioamination of Arynes with S-(o-Bromoaryl)-S-methylsulfilimines and Subsequent Intramolecular Buchwald–Hartwig Amination. Chem Lett. 2018.07; 47 (7): 825-828. ( DOI )

  16. Meguro T, Yoshida S, Igawa K, Tomooka K, Hosoya T. Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation. Org Lett. 2018.06; 20 (13): 4126-4130. ( PubMed, DOI )

  17. Yoshida S, Kuribara T, Morita T, Matsuzawa T, Morimoto K, Kobayashi T, Hosoya T. Expanding the synthesizable multisubstituted benzo[b]thiophenes via 6,7-thienobenzynes generated from o-silylaryl triflate-type precursors. RSC Adv. 2018.06; 8 (39): 21754-21758. ( DOI )

  18. Kii I, Hirahara-Owada S, Yamaguchi M, Niwa T, Koike Y, Sonamoto R, Ito H, Takahashi K, Yokoyama C, Hayashi T, Hosoya T, Watanabe Y. Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ. Anal Biochem. 2018.04; 549 174-183. ( PubMed, DOI )

  19. Yoshida S, Kanno K, Kii I, Misawa Y, Hagiwara M, Hosoya T. Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions. Chem Commun. 2018.04; 54 (30): 3705-3708. ( PubMed, DOI )

  20. Ajiro M, Sakai H, Onogi H, Yamamoto M, Sumi E, Sawada T, Nomura T, Kabashima K, Hosoya T, Hagiwara M. CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia. Clin Cancer Res. 2018.04; ( PubMed, DOI )

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