論文・総説 - 細谷 孝充
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Morita T, Nishiyama Y, Yoshida S, Hosoya T. Facile Synthesis of Multisubstituted Benzo[b]furans via 2,3-Disubstituted 6,7-Furanobenzynes Generated from ortho-Iodoaryl Triflate-type Precursors. Chem Lett. 2017.01; 46 (1): 118-121. ( DOI )
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Yoshida S, Nakajima H, Uchida K, Yano T, Kondo M, Matsushita T, Hosoya T. Reactions of Arynes with Sulfoximines: Formal Sulfinylamination vs. N-Arylation. Chem Lett. 2017.01; 46 (1): 77-80. ( DOI )
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Morita T, Yoshida S, Kondo M, Matsushita T, Hosoya T. Facile Diversification of Simple Benzo[b]thiophenes via Thienobenzyne Intermediates. Chem Lett. 2017.01; 46 (1): 81-84. ( DOI )
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Yoshida S, Nakamura Y, Uchida K, Hazama Y, Hosoya T. Aryne Relay Chemistry en Route to Aminoarenes: Synthesis of 3-Aminoaryne Precursors via Regioselective Silylamination of 3-(Triflyloxy)arynes.. Org Lett. 2016.12; 18 (23): 6212-6215. ( PubMed, DOI )
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Ochiai H, Niwa T, Hosoya T. Stereoinversion of Stereocongested Carbocyclic Alcohols via Triflylation and Subsequent Treatment with Aqueous N,N-Dimethylformamide. Org Lett. 2016.12; 18 (23): 5982-5985. ( PubMed, DOI )
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Okamoto-Uchida Y, Yu R, Miyamura N, Arima N, Ishigami-Yuasa M, Kagechika H, Yoshida S, Hosoya T, Nawa M, Kasama T, Asaoka Y, Alois RW, Elling U, Penninger JM, Nishina S, Azuma N, Nishina H. The mevalonate pathway regulates primitive streak formation via protein farnesylation. Sci Rep. 2016.11; 6 37697. ( PubMed, DOI )
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Doi H, Sato K, Shindou H, Sumi K, Koyama H, Hosoya T, Watanabe Y, Ishii S, Tsukada H, Nakanishi K, Suzuki M. Blood-brain barrier permeability of ginkgolide: Comparison of the behavior of PET probes 7α-[18F]fluoro- and 10-O-p-[11C]methylbenzyl ginkgolide B in monkey and rat brains. Bioorg Med Chem. 2016.11; 24 (21): 5148-5157. ( PubMed, DOI )
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Sumida Y, Sumida T, Hashizume D, Hosoya T. Preparation of Aryne-Nickel Complexes from ortho-Borylaryl Triflates. Org Lett. 2016.11; 18 (21): 5600-5603. ( PubMed, DOI )
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Tanaka T, Okuyama-Dobashi K, Murakami S, Chen W, Okamoto T, Ueda K, Hosoya T, Matsuura Y, Ryo A, Tanaka Y, Hagiwara M, Moriishi K. Inhibitory effect of CDK9 inhibitor FIT-039 on hepatitis B virus propagation. Antiviral Res. 2016.09; 133 156-164. ( PubMed, DOI )
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Yoshida S, Yano T, Nishiyama Y, Misawa Y, Kondo M, Matsushita T, Igawa K, Tomooka K, Hosoya T. Thiazolobenzyne: a versatile intermediate for multisubstituted benzothiazoles. Chem Commun. 2016.09; 52 (75): 11199-11202. ( PubMed, DOI )
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Controlled Generation of 3-Triflyloxyarynes. Synthesis. 2016.08; 48 (23): 4099-4109. ( DOI )
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Yoshida S, Shimomori K, Kim Y, Hosoya T. Single C-F Bond Cleavage of Trifluoromethylarenes with an ortho-Silyl Group. Angew Chem Int Ed Engl. 2016.08; 55 (35): 10406-10409. ( PubMed, DOI )
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Yoshida S, Morita T, Hosoya T. Synthesis of Diverse Benzotriazoles from Aryne Precursors Bearing an Azido Group via Inter- and Intramolecular Cycloadditions. Chem Lett. 2016.07; 45 (7): 726-728. ( DOI )
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Uetake Y, Niwa T, Hosoya T. Rhodium-Catalyzed ipso-Borylation of Alkylthioarenes via C-S Bond Cleavage. Org Lett. 2016.06; 18 (11): 2758-2761. ( PubMed, DOI )
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Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, Kato-Sumida T, Koike Y, Abe M, Nonaka Y, Ikura T, Ito N, Shibuya H, Hosoya T, Hagiwara M. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016.04; 7 11391. ( PubMed, DOI )
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Tomabechi Y, Hosoya T, Ehara H, Sekine S, Shirouzu M, Inouye S. Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine. Biochem Biophys Res Commun. 2016.01; 470 (1): 88-93. ( PubMed, DOI )
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Yoshida S, Sugimura Y, Hazama Y, Nishiyama Y, Yano T, Shimizu S, Hosoya T. A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates. Chem Commun. 2015.12; 51 (93): 16613-16616. ( PubMed, DOI )
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Yoshida S, Hosoya T. The Renaissance and Bright Future of Synthetic Aryne Chemistry. Chem Lett. 2015.11; 44 (11): 1450-1460. ( DOI )
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Niwa T, Ochiai H, Watanabe Y, Hosoya T. Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C-F Bond Functionalizations. J Am Chem Soc. 2015.11; 137 (45): 14313-14318. ( PubMed, DOI )
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Yoshida S, Yano T, Misawa Y, Sugimura Y, Igawa K, Shimizu S, Tomooka K, Hosoya T. Direct thioamination of arynes via reaction with sulfilimines and migratory N-arylation. J Am Chem Soc. 2015.11; 137 (44): 14071-14074. ( PubMed, DOI )