論文・総説 - 細谷 孝充
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Muraki M, Ohkawara B, Hosoya T, Onogi H, Koizumi J, Koizumi T, Sumi K, Yomoda J, Murray MV, Kimura H, Furuichi K, Shibuya H, Krainer AR, Suzuki M, Hagiwara M. Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem. 2004.06; 279 (23): 24246-24254. ( PubMed, DOI )
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Hosoya T, Hiramatsu T, Ikemoto T, Nakanishi M, Aoyama H, Hosoya A, Iwata T, Maruyama K, Endo M, Suzuki M. Novel bifunctional probe for radioisotope-free photoaffinity labeling: compact structure comprised of photospecific ligand ligation and detectable tag anchoring units. Org Biomol Chem. 2004.03; 2 (5): 637-641. ( PubMed, DOI )
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Hosoya T, Wakao M, Kondo Y, Doi H, Suzuki M. Rapid methylation of terminal acetylenes by the Stille coupling of methyl iodide with alkynyltributylstannanes: a general protocol potentially useful for the synthesis of short-lived 11CH3-labeled PET tracers with a 1-propynyl group. Org Biomol Chem. 2004.01; 2 (1): 24-27. ( PubMed, DOI )
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Suzuki M, Doi H, Hosoya T, Långström B, Watanabe Y.. Rapid methylation on carbon frameworks leading to the synthesis of a PET tracer capable of imaging a novel CNS-type prostacyclin receptor in living human brain. Trends Anal Chem. 2004; 23 (8): 595-607. ( DOI )
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Hosoya T, Aoyama H, Ikemoto T, Kihara Y, Hiramatsu T, Endo M, Suzuki M. Dantrolene analogues revisited: general synthesis and specific functions capable of discriminating two kinds of Ca2+ release from sarcoplasmic reticulum of mouse skeletal muscle. Bioorg Med Chem. 2003.03; 11 (5): 663-673. ( PubMed )
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Hosoya T, Aoyama H, Ikemoto T, Hiramatsu T, Kihara Y, Endo M, Suzuki M. [(125)I]-N-[(3-azido-5-iodo)benzyl]dantrolene and [(125)I]-N-[[3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)]benzyl]dantrolene: photoaffinity probes specific for the physiological Ca(2+) release from sarcoplasmic reticulum of skeletal muscle. Bioorg Med Chem Lett. 2002.11; 12 (22): 3263-3265. ( PubMed )
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Ikenoya M, Hidaka H, Hosoya T, Suzuki M, Yamamoto N, Sasaki Y. Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem. 2002.04; 81 (1): 9-16. ( PubMed )
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Takamatsu H, Tsukada H, Watanabe Y, Cui Y, Kataoka Y, Hosoya T, Suzuki M, Watanabe Y. Specific ligand for a central type prostacyclin receptor attenuates neuronal damage in a rat model of focal cerebral ischemia. Brain Res. 2002.01; 925 (2): 176-182. ( PubMed )
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Hamura T, Hosoya T, Yamaguchi H, Kuriyama Y, Tanabe M, Miyamoto M, Yasui Y, Matsumoto T, Suzuki K.. Facile access to versatile polyaromatic building blocks: selectively protected benzocyclobutenedione derivatives via regioselective [2 + 2] cycloaddition of α-alkoxybenzyne and ketene silyl acetal. Helv Chim Acta. 2002; 85 (11): 3589-3604. ( DOI )
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Ikemoto T, Hosoya T, Aoyama H, Kihara Y, Suzuki M, Endo M. Effects of dantrolene and its derivatives on Ca(2+) release from the sarcoplasmic reticulum of mouse skeletal muscle fibres. Br J Pharmacol. 2001.10; 134 (4): 729-736. ( PubMed, DOI )
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Hosoya T, Hamura T, Kuriyama Y, Miyamoto M, Matsumoto T, Suzuki K.. Silicon-Directed Regioselective [2+2] Cycloaddition of α-Alkoxybenzyne and Ketene Silyl Acetals. Synlett. 2000; (4): 520-522. ( DOI )
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Futagami S, Ohashi Y, Imura K, Hosoya T, Omori K, Matsumoto T, Suzuki K.. Total synthesis of ravidomycin: revision of absolute and relative stereochemistry. Tetrahedron Lett. 2000; 41 (7): 1063-1067. ( DOI )
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Furuta K, Hosoya T, Tomokiyo K, Okuda S, Kuniyasu A, Nakayama H, Ishikawa T, Suzuki M. [35S]S-[5-(4-benzoylphenyl)pentyl]glutathione: a versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling. Bioorg Med Chem Lett. 1999.09; 9 (18): 2661-2666. ( PubMed )
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Hosoya T, Takashiro E, Yamamoto Y, Matsumoto T, Suzuki K.. Total Syntheses of BE-12406 A and Its C(8)-Vinyl Analog. Heterocycles. 1996; 42 (1): 397-414. ( DOI )
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Hosoya T, Ohashi Y, Matsumoto T, Suzuki K.. On the Stereochemistry of Aryl C-Glycosides: Unusual Behavior of Bis-TBDPS Protected Aryl C-Olivosides. Tetrahedron Lett. 1996; 37 (5): 663-666. ( DOI )
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Suzuki K, Matsumoto T, Hosoya T.. Total Synthesis of the Gilvocarcins. J Synth Org Chem, Jpn. 1995; 53 (11): 1045-1054.
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Hosoya T, Hasegawa T, Kuriyama Y, Suzuki K. Stereospecificity in [2 + 2] Cycloaddition of Benzyne and Ketene Silyl Acetal. Tetrahedron Lett. 1995; 36 (19): 3377-3380. ( DOI )
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Hosoya T, Kuriyama Y, Suzuki K.. Convenient Synthesis of Phthalides via Regioselective Baeyer-Villiger Oxidation of Benzocyclobutenones. Synlett. 1995; (6): 635-638. ( DOI )
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Hosoya T, Hasegawa T, Kuriyama Y, Matsumoto T, Suzuki K.. [2 + 2] Cycloaddition of Benzyne and Ketene Silyl Acetal as an Efficient Route to Benzocyclobutenones. Synlett. 1995; (2): 177-179. ( DOI )
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Hosoya T, Takashiro E, Matsumoto T, Suzuki K.. First Total Synthesis of BE-12406 A. Tetrahedron Lett. 1994; 35 (26): 4591-4594. ( DOI )