論文・総説 - 烏山　一

101. Belkina NV, Liu Y, Hao JJ, Karasuyama H, Shaw S. LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Proc Natl Acad Sci U S A. 2009.03; 106 (12): 4707-4712. ( PubMed, DOI )

102. Khodoun M, Strait R, Orekov T, Hogan S, Karasuyama H, Herbert DR, Kohl J, Finkelman FD. Peanuts can contribute to anaphylactic shock by activating complement. J Allergy Clin Immunol. 2009.02; 123 (2): 342-351. ( PubMed, DOI )

103. Minegishi Y, Karasuyama H. Defects in Jak-STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency. Int Immunol. 2009.02; 21 (2): 105-112. ( PubMed, DOI )

104. Hida S, Yamasaki S, Sakamoto Y, Takamoto M, Obata K, Takai T, Karasuyama H, Sugane K, Saito T, Taki S. Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol. 2009.02; 10 (2): 214-222. ( PubMed, DOI )

105. Karasuyama H, Mukai K, Tsujimura Y, Obata K. Newly discovered roles for basophils: a neglected minority gains new respect. Nat Rev Immunol. 2009.01; 9 (1): 9-13. ( PubMed, DOI )

106. Yoshikawa S, Kawano Y, Minegishi Y, Karasuyama H. The skewed heavy-chain repertoire in peritoneal B-1 cells is predetermined by the selection via pre-B cell receptor during B cell ontogeny in the fetal liver. Int Immunol. 2009.01; 21 (1): 43-52. ( PubMed, DOI )

107. Takada T, Shitara H, Matsuoka K, Kojima E, Ishii R, Kikkawa Y, Taya C, Karasuyama H, Kohno K, Yonekawa H. A novel hairless mouse model on an atopic dermatitis-prone genetic background generated by receptor-mediated transgenesis. Transgenic Res. 2008.12; 17 (6): 1155-1162. ( PubMed, DOI )

108. Watanabe M, Satoh T, Yamamoto Y, Kanai Y, Karasuyama H, Yokozeki H. Overproduction of IgE induces macrophage-derived chemokine (CCL22) secretion from basophils. J Immunol. 2008.10; 181 (8): 5653-5659. ( PubMed )

109. Minegishi Y, Karasuyama H. Genetic origins of hyper-IgE syndrome. Curr Allergy Asthma Rep. 2008.09; 8 (5): 386-391. ( PubMed )

110. Tsujimura Y, Obata K, Mukai K, Shindou H, Yoshida M, Nishikado H, Kawano Y, Minegishi Y, Shimizu T, Karasuyama H. Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity. 2008.04; 28 (4): 581-589. ( PubMed, DOI )

111. Yasuda T, Sanjo H, Pages G, Kawano Y, Karasuyama H, Pouyssegur J, Ogata M, Kurosaki T. Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity. 2008.04; 28 (4): 499-508. ( PubMed, DOI )

112. Minegishi Y, Karasuyama H. Hyperimmunoglobulin E syndrome and tyrosine kinase 2 deficiency. Curr Opin Allergy Clin Immunol. 2007.12; 7 (6): 506-509. ( PubMed, DOI )

113. Kojima T, Obata K, Mukai K, Sato S, Takai T, Minegishi Y, Karasuyama H. Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner. J Immunol. 2007.11; 179 (10): 7093-7100. ( PubMed )

114. Obata K, Mukai K, Tsujimura Y, Ishiwata K, Kawano Y, Minegishi Y, Watanabe N, Karasuyama H. Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood. 2007.08; 110 (3): 913-920. ( PubMed, DOI )

115. Minegishi Y, Saito M, Tsuchiya S, Tsuge I, Takada H, Hara T, Kawamura N, Ariga T, Pasic S, Stojkovic O, Metin A, Karasuyama H. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature. 2007.08; 448 (7157): 1058-1062. ( PubMed, DOI )

116. Ochiai K, Katoh Y, Ikura T, Hoshikawa Y, Noda T, Karasuyama H, Tashiro S, Muto A, Igarashi K. Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells. J Biol Chem. 2006.12; 281 (50): 38226-38234. ( PubMed, DOI )

117. Minegishi Y, Saito M, Morio T, Watanabe K, Agematsu K, Tsuchiya S, Takada H, Hara T, Kawamura N, Ariga T, Kaneko H, Kondo N, Tsuge I, Yachie A, Sakiyama Y, Iwata T, Bessho F, Ohishi T, Joh K, Imai K, Kogawa K, Shinohara M, Fujieda M, Wakiguchi H, Pasic S, Abinun M, Ochs HD, Renner ED, Jansson A, Belohradsky BH, Metin A, Shimizu N, Mizutani S, Miyawaki T, Nonoyama S, Karasuyama H. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity. 2006.11; 25 (5): 745-755. ( PubMed, DOI )

118. Yamamoto M, Hayashi K, Nojima T, Matsuzaki Y, Kawano Y, Karasuyama H, Goitsuka R, Kitamura D. BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces kappa gene rearrangement. Blood. 2006.10; 108 (8): 2703-2711. ( PubMed, DOI )

119. Kawano Y, Yoshikawa S, Minegishi Y, Karasuyama H. Pre-B cell receptor assesses the quality of IgH chains and tunes the pre-B cell repertoire by delivering differential signals. J Immunol. 2006.08; 177 (4): 2242-2249. ( PubMed )

120. Kubota T, Mukai K, Minegishi Y, Karasuyama H. Different stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains. J Immunol. 2006.06; 176 (11): 7008-7014. ( PubMed )