Published Papers & Misc - HOSOYA Takamitsu

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  1. Yoshida S, Nonaka T, Morita T, Hosoya T. Modular synthesis of bis- and tris-1,2,3-triazoles by permutable sequential azide-aryne and azide-alkyne cycloadditions. Org Biomol Chem. 2014.10; 12 (38): 7489-7493. ( PubMed, DOI )

  2. Yoshida S, Hatakeyama Y, Johmoto K, Uekusa H, Hosoya T. Transient protection of strained alkynes from click reaction via complexation with copper. J Am Chem Soc. 2014.10; 136 (39): 13590-13593. ( PubMed, DOI )

  3. Inouye S, Sato J-i, Sahara-Miura Y, Hosoya T, Suzuki T. Unconventional secretion of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) in mammalian cells. Biochem Biophys Res Commun. 2014.08; 450 (4): 1313-1319. ( PubMed, DOI )

  4. Yamamoto M, Onogi H, Kii I, Yoshida S, Iida K, Sakai H, Abe M, Tsubota T, Ito N, Hosoya T, Hagiwara M. CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses. J Clin Invest. 2014.08; 124 (8): 3479-3488. ( PubMed, DOI )

  5. Suzuki M, Doi H, Koyama H, Zhang Z, Hosoya T, Onoe H, Watanabe Y. Pd0-mediated rapid cross-coupling reactions, the rapid C-[11C]methylations, revolutionarily advancing the syntheses of short-lived PET molecular probes. Chem Rec. 2014.06; 14 (3): 516-541. ( PubMed, DOI )

  6. Yoshida S, Misawa Y, Hosoya T. Formal C–H-Azidation Based Shortcut to Diazido Building Blocks for the Versatile Preparation of Photoaffinity Labeling Probes. Eur J Org Chem. 2014.05; (19): 3991-3995. ( DOI )

  7. Takahashi K, Hosoya T, Onoe K, Doi H, Nagata H, Hiramatsu T, Li XL, Watanabe Y, Wada Y, Takashima T, Suzuki M, Onoe H, Watanabe Y. 11C-Cetrozole: An Improved C-11C-Methylated PET Probe for Aromatase Imaging in the Brain. J Nucl Med. 2014.03; 55 (5): 852-857. ( PubMed, DOI )

  8. Inouye S, Sato J, Sahara-Miura Y, Yoshida S, Hosoya T. Luminescence enhancement of the catalytic 19kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions. Biochem Biophys Res Commun. 2014.02; 445 (1): 157-162. ( PubMed, DOI )

  9. Sumi K, Inoue Y, Nishio M, Naito Y, Hosoya T, Suzuki M, Hidaka H. IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys. Bioorg Med Chem Lett. 2014.02; 24 (3): 831-834. ( PubMed, DOI )

  10. Yoshida S, Uchida K, Hosoya T. Generation of arynes triggered by sulfoxide-metal exchange reaction of ortho-sulfinylaryl triflates. Chem Lett. 2014; 43 (1): 116-118. ( DOI )

  11. Tanaka K, Nakamoto Y, Siwu ER, Pradipta AR, Morimoto K, Fujiwara T, Yoshida S, Hosoya T, Tamura Y, Hirai G, Sodeoka M, Fukase K. Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation. Org Biomol Chem. 2013.11; 11 (42): 7326-7333. ( PubMed, DOI )

  12. Miyajima M, Kusuhara H, Takahashi K, Takashima T, Hosoya T, Watanabe Y, Sugiyama Y. Investigation of the effect of active efflux at the blood-brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system. J Pharm Sci. 2013.09; 102 (9): 3309-3319. ( PubMed, DOI )

  13. Inouye S, Sato J, Sahara-Miura Y, Yoshida S, Kurakata H, Hosoya T. C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase. Biochem Biophys Res Commun. 2013.07; 437 (1): 23-28. ( PubMed, DOI )

  14. Sumida Y, Kato T, Hosoya T. Generation of arynes via ate complexes of arylboronic esters with an ortho-leaving group. Org Lett. 2013.06; 15 (11): 2806-2809. ( PubMed, DOI )

  15. Inouye S, Sahara-Miura Y, Sato J, Iimori R, Yoshida S, Hosoya T. Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines. Protein Expr Purif. 2013.03; 88 (1): 150-156. ( PubMed, DOI )

  16. Koyama H, Zhang Z, Ijuin R, Siqin, Son J, Hatta Y, Ohta M, Wakao M, Hosoya T, Doi H, Suzuki M.. Pd(0)-mediated rapid coupling of methyl iodide with excess amounts of benzyl- and cinnamylboronic acid esters: efficient method for incorporation of positron-emitting (11)C radionuclide into organic frameworks by coupling between two sp(3)-hybridized carbons. RSC Adv. 2013; 3 (24): 9391-9401. ( DOI )

  17. Yoshida S, Hosoya T. Synthesis of diverse aromatic oxophosphorus compounds by the Michaelis-Arbuzov-type reaction of arynes. Chem Lett. 2013; 42 (6): 583-585. ( DOI )

  18. Yoshimura SH, Khan S, Ohno S, Yokogawa T, Nishikawa K, Hosoya T, Maruyama H, Nakayama Y, Takeyasu K. Site-specific attachment of a protein to a carbon nanotube end without loss of protein function. Bioconjug Chem. 2012.07; 23 (7): 1488-1493. ( PubMed, DOI )

  19. Sumida Y, Kato T, Yoshida S, Hosoya T. Palladium-catalyzed regio- and stereoselective hydrosilylation of electron-deficient alkynes. Org Lett. 2012.03; 14 (6): 1552-1555. ( PubMed, DOI )

  20. Ozawa M, Takahashi K, Akazawa KH, Takashima T, Nagata H, Doi H, Hosoya T, Wada Y, Cui Y, Kataoka Y, Watanabe Y. PET of aromatase in gastric parietal cells using 11C-vorozole. J Nucl Med. 2011.12; 52 (12): 1964-1969. ( PubMed, DOI )

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