Published Papers & Misc - HOSOYA Takamitsu

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  1. Meguro T, Terashima N, Ito H, Koike Y, Kii I, Yoshida S, Hosoya T. Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells. Chem Commun. 2018.07; 54 (57): 7904-7907. ( PubMed, DOI )

  2. Matsuzawa T, Uchida K, Yoshida S, Hosoya T. Synthesis of Diverse Phenothiazines by Direct Thioamination of Arynes with S-(o-Bromoaryl)-S-methylsulfilimines and Subsequent Intramolecular Buchwald–Hartwig Amination. Chem Lett. 2018.07; 47 (7): 825-828. ( DOI )

  3. Meguro T, Yoshida S, Igawa K, Tomooka K, Hosoya T. Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation. Org Lett. 2018.06; 20 (13): 4126-4130. ( PubMed, DOI )

  4. Yoshida S, Kuribara T, Morita T, Matsuzawa T, Morimoto K, Kobayashi T, Hosoya T. Expanding the synthesizable multisubstituted benzo[b]thiophenes via 6,7-thienobenzynes generated from o-silylaryl triflate-type precursors. RSC Adv. 2018.06; 8 (39): 21754-21758. ( DOI )

  5. Kii I, Hirahara-Owada S, Yamaguchi M, Niwa T, Koike Y, Sonamoto R, Ito H, Takahashi K, Yokoyama C, Hayashi T, Hosoya T, Watanabe Y. Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ. Anal Biochem. 2018.04; 549 174-183. ( PubMed, DOI )

  6. Yoshida S, Kanno K, Kii I, Misawa Y, Hagiwara M, Hosoya T. Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions. Chem Commun. 2018.04; 54 (30): 3705-3708. ( PubMed, DOI )

  7. Ajiro M, Sakai H, Onogi H, Yamamoto M, Sumi E, Sawada T, Nomura T, Kabashima K, Hosoya T, Hagiwara M. CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia. Clin Cancer Res. 2018.04; ( PubMed, DOI )

  8. Kanemoto K, Yoshida S, Hosoya T. Modified Conditions for Copper-Catalyzed ipso-Thiolation of Arylboronic Acid Esters with Thiosulfonates. Chem Lett. 2018.01; 47 (1): 85-88. ( DOI )

  9. Kusuhara H, Takashima T, Fujii H, Takashima T, Tanaka M, Ishii A, Tazawa S, Takahashi K, Takahashi K, Tokai H, Yano T, Kataoka M, Inano A, Yoshida S, Hosoya T, Sugiyama Y, Yamashita S, Hojo T, Watanabe Y. Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects. Drug Metab Pharmacokinet. 2017.12; 32 (6): 293-300. ( PubMed, DOI )

  10. Yoshida S, Shimizu K, Uchida K, Hazama Y, Igawa K, Tomooka K, Hosoya T. Construction of Condensed Polycyclic Aromatic Frameworks through Intramolecular Cycloaddition Reactions Involving Arynes Bearing an Internal Alkyne Moiety. Chem Eur J. 2017.11; 23 (61): 15332-15335. ( PubMed, DOI )

  11. Matsuzawa T, Uchida K, Yoshida S, Hosoya T. Synthesis of Diverse o-Arylthio-Substituted Diaryl Ethers by Direct Oxythiolation of Arynes with Diaryl Sulfoxides Involving Migratory O-Arylation. Org Lett. 2017.10; 19 (20): 5521-5524. ( PubMed, DOI )

  12. Hatakeyama M, Sakamoto Y, Ogata K, Sumida Y, Sumida T, Hosoya T, Nakamura S. A study on an unusual SN2 mechanism in the methylation of benzyne through nickel-complexation. Phys Chem Chem Phys. 2017.10; 19 (39): 26926-26933. ( PubMed, DOI )

  13. Sakaguchi H, Uetake Y, Ohashi M, Niwa T, Ogoshi S, Hosoya T. Copper-Catalyzed Regioselective Monodefluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes. J Am Chem Soc. 2017.09; 139 (36): 12855-12862. ( PubMed, DOI )

  14. Nakano-Kobayashi A, Awaya T, Kii I, Sumida Y, Okuno Y, Yoshida S, Sumida T, Inoue H, Hosoya T, Hagiwara M. Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice. Proc Natl Acad Sci USA. 2017.09; 114 (38): 10268-10273. ( PubMed, DOI )

  15. Kanemoto K, Sugimura Y, Shimizu S, Yoshida S, Hosoya T. Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates. Chem Commun. 2017.09; 53 (77): 10640-10643. ( PubMed, DOI )

  16. Niwa T, Ochiai H, Hosoya T. Facile Transformation of α,β-Unsaturated Carboxylic Acids to Alkenylboronic Esters via Rhodium-Catalyzed Decarbonylative Borylation of α,β-Unsaturated Thioesters. Chem Lett. 2017.09; 46 (9): 1315-1318. ( DOI )

  17. Meguro T, Yoshida S, Hosoya T. Sequential Molecular Conjugation using Thiophene S,S-Dioxides Bearing a Clickable Functional Group. Chem Lett. 2017.08; 46 (8): 1137-1140. ( DOI )

  18. Nishiyama Y, Hazama Y, Yoshida S, Hosoya T. Synthesis of Unsymmetrical Tertiary Phosphine Oxides via Sequential Substitution Reaction of Phosphonic Acid Dithioesters with Grignard Reagents. Org Lett. 2017.07; 19 (14): 3899-3902. ( PubMed, DOI )

  19. Furubayashi T, Motohashi K, Wakao K, Matsuda T, Kii I, Hosoya T, Hayashi N, Sadaie M, Ishikawa F, Matsushita M, Fujiyoshi S. Three-Dimensional Localization of an Individual Fluorescent Molecule with Angstrom Precision. J Am Chem Soc. 2017.07; 139 (26): 8990-8994. ( PubMed, DOI )

  20. Nakamura Y, Yoshida S, Hosoya T. Facile Synthesis of Phthalides from Methyl ortho-Iodobenzoates and Ketones via an Iodine–Magnesium Exchange Reaction Using a Silylmethyl Grignard Reagent. Chem Lett. 2017.06; 46 (6): 858-861. ( DOI )

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