Published Papers & Misc - HOSOYA Takamitsu

201. Abe M, Ohno S, Yokogawa T, Nakanishi T, Arisaka F, Hosoya T, Hiramatsu T, Suzuki M, Ogasawara T, Sawasaki T, Nishikawa K, Kitamura M, Hori H, Endo Y. Detection of structural changes in a cofactor binding protein by using a wheat germ cell-free protein synthesis system coupled with unnatural amino acid probing. Proteins. 2007.05; 67 (3): 643-652. ( PubMed, DOI )

202. Ohno S, Matsui M, Yokogawa T, Nakamura M, Hosoya T, Hiramatsu T, Suzuki M, Hayashi N, Nishikawa K. Site-selective post-translational modification of proteins using an unnatural amino acid, 3-azidotyrosine. J Biochem. 2007.03; 141 (3): 335-343. ( PubMed, DOI )

203. Cui Y, Takamatsu H, Kakiuchi T, Ohba H, Kataoka Y, Yokoyama C, Onoe H, Watanabe Y, Hosoya T, Suzuki M, Noyori R, Tsukada H, Watanabe Y. Neuroprotection by a central nervous system-type prostacyclin receptor ligand demonstrated in monkeys subjected to middle cerebral artery occlusion and reperfusion: a positron emission tomography study. Stroke. 2006.11; 37 (11): 2830-2836. ( PubMed, DOI )

204. Fukuhara T, Hosoya T, Shimizu S, Sumi K, Oshiro T, Yoshinaka Y, Suzuki M, Yamamoto N, Herzenberg LA, Herzenberg LA, Hagiwara M. Utilization of host SR protein kinases and RNA-splicing machinery during viral replication. Proc Natl Acad Sci USA. 2006.07; 103 (30): 11329-11333. ( PubMed, DOI )

205. Hosoya T, Sumi K, Doi H, Wakao M, Suzuki M. Rapid methylation on carbon frameworks useful for the synthesis of 11CH3-incorporated PET tracers: Pd(0)-mediated rapid coupling of methyl iodide with an alkenyltributylstannane leading to a 1-methylalkene. Org Biomol Chem. 2006.02; 4 (3): 410-415. ( PubMed, DOI )

206. Hosoya T, Hiramatsu T, Ikemoto T, Aoyama H, Ohmae T, Endo M, Suzuki M. Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca2+ release from sarcoplasmic reticulum of skeletal muscle. Bioorg Med Chem Lett. 2005.03; 15 (5): 1289-1294. ( PubMed, DOI )

207. Suzuki M, Doi H, Kato K, Hosoya T, Watanabe Y, Watanabe Y. Designed molecular probes in brain research: molecular imaging of IP2 receptor in the human brain. Jpn J Neuropsychopharmacol. 2004.08; 24 (4): 221-229. ( PubMed )

208. Muraki M, Ohkawara B, Hosoya T, Onogi H, Koizumi J, Koizumi T, Sumi K, Yomoda J, Murray MV, Kimura H, Furuichi K, Shibuya H, Krainer AR, Suzuki M, Hagiwara M. Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem. 2004.06; 279 (23): 24246-24254. ( PubMed, DOI )

209. Hosoya T, Hiramatsu T, Ikemoto T, Nakanishi M, Aoyama H, Hosoya A, Iwata T, Maruyama K, Endo M, Suzuki M. Novel bifunctional probe for radioisotope-free photoaffinity labeling: compact structure comprised of photospecific ligand ligation and detectable tag anchoring units. Org Biomol Chem. 2004.03; 2 (5): 637-641. ( PubMed, DOI )

210. Hosoya T, Wakao M, Kondo Y, Doi H, Suzuki M. Rapid methylation of terminal acetylenes by the Stille coupling of methyl iodide with alkynyltributylstannanes: a general protocol potentially useful for the synthesis of short-lived 11CH3-labeled PET tracers with a 1-propynyl group. Org Biomol Chem. 2004.01; 2 (1): 24-27. ( PubMed, DOI )

211. Suzuki M, Doi H, Hosoya T, Långström B, Watanabe Y.. Rapid methylation on carbon frameworks leading to the synthesis of a PET tracer capable of imaging a novel CNS-type prostacyclin receptor in living human brain. Trends Anal Chem. 2004; 23 (8): 595-607. ( DOI )

212. Hosoya T, Aoyama H, Ikemoto T, Kihara Y, Hiramatsu T, Endo M, Suzuki M. Dantrolene analogues revisited: general synthesis and specific functions capable of discriminating two kinds of Ca2+ release from sarcoplasmic reticulum of mouse skeletal muscle. Bioorg Med Chem. 2003.03; 11 (5): 663-673. ( PubMed )

213. Hosoya T, Aoyama H, Ikemoto T, Hiramatsu T, Kihara Y, Endo M, Suzuki M. [(125)I]-N-[(3-azido-5-iodo)benzyl]dantrolene and [(125)I]-N-[[3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)]benzyl]dantrolene: photoaffinity probes specific for the physiological Ca(2+) release from sarcoplasmic reticulum of skeletal muscle. Bioorg Med Chem Lett. 2002.11; 12 (22): 3263-3265. ( PubMed )

214. Ikenoya M, Hidaka H, Hosoya T, Suzuki M, Yamamoto N, Sasaki Y. Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem. 2002.04; 81 (1): 9-16. ( PubMed )

215. Takamatsu H, Tsukada H, Watanabe Y, Cui Y, Kataoka Y, Hosoya T, Suzuki M, Watanabe Y. Specific ligand for a central type prostacyclin receptor attenuates neuronal damage in a rat model of focal cerebral ischemia. Brain Res. 2002.01; 925 (2): 176-182. ( PubMed )

216. Hamura T, Hosoya T, Yamaguchi H, Kuriyama Y, Tanabe M, Miyamoto M, Yasui Y, Matsumoto T, Suzuki K.. Facile access to versatile polyaromatic building blocks: selectively protected benzocyclobutenedione derivatives via regioselective [2 + 2] cycloaddition of α-alkoxybenzyne and ketene silyl acetal. Helv Chim Acta. 2002; 85 (11): 3589-3604. ( DOI )

217. Ikemoto T, Hosoya T, Aoyama H, Kihara Y, Suzuki M, Endo M. Effects of dantrolene and its derivatives on Ca(2+) release from the sarcoplasmic reticulum of mouse skeletal muscle fibres. Br J Pharmacol. 2001.10; 134 (4): 729-736. ( PubMed, DOI )

218. Hosoya T, Hamura T, Kuriyama Y, Miyamoto M, Matsumoto T, Suzuki K.. Silicon-Directed Regioselective [2+2] Cycloaddition of α-Alkoxybenzyne and Ketene Silyl Acetals. Synlett. 2000; (4): 520-522. ( DOI )

219. Futagami S, Ohashi Y, Imura K, Hosoya T, Omori K, Matsumoto T, Suzuki K.. Total synthesis of ravidomycin: revision of absolute and relative stereochemistry. Tetrahedron Lett. 2000; 41 (7): 1063-1067. ( DOI )

220. Furuta K, Hosoya T, Tomokiyo K, Okuda S, Kuniyasu A, Nakayama H, Ishikawa T, Suzuki M. [35S]S-[5-(4-benzoylphenyl)pentyl]glutathione: a versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling. Bioorg Med Chem Lett. 1999.09; 9 (18): 2661-2666. ( PubMed )