Published Papers & Misc - HOSOYA Takamitsu

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  1. Toyomoto M, Kurihara T, Nakagawa T, Inoue A, Kimura R, Kii I, Sawada T, Ogihara T, Nagayasu K, Kishi T, Onogi, Im D, Asada H, Iwata S, Taguchi J, Sumida Y, Yoshida S, Aoki J, Hosoya T, Hagiwara M. Discovery and development of an oral analgesic targeting the α2B adrenoceptor. Proc Natl Acad Sci U S A. 2025.08; 122 (32): e2500006122. ( PubMed, DOI )

  2. Taguchi J, Ohata Y, Akimoto H, Tabuchi H, Igawa K, Tomooka K, Niwa T, Hosoya T. Boronate Formation-Triggered Azide-Alkyne Cycloaddition. Org Lett. 2025.05; 27 (17): 4428-4433. ( PubMed, DOI )

  3. Suzuki S, Umezawa K, Furuie G, Kikuchi M, Nakamura DGM, Fukahori N, Kimura N, Yamakawa M, Niwa T, Umehara T, Hosoya T, Kii I. Temperature vaulting: A method for screening of slow- and tight-binding inhibitors that selectively target kinases in their non-native state. Eur J Med Chem. 2025.05; 295 117789. ( PubMed, DOI )

  4. Watanabe K, Uetake Y, Hata M, Kuwano A, Yamamoto R, Yamamoto Y, Kodera M, Kitagishi H, Niwa T, Hosoya T. Red-light Emitting Orthogonally Trireactive Gold Nanoclusters for the Synthesis of Multifunctionalized Nanomaterials. Small. 2025.04; 21 (17): e2408747. ( PubMed, DOI )

  5. Tanaka T, Tabata S, Nakamura K, Hazama Y, Sakata Y, Hosoya T, Yoshida S. Synthesis of Multisubstituted Naphthalenes through Consecutive Aryne Reactions. Bull Chem Soc Jpn. 2025.01; 98 (1): uoaf001 . ( DOI )

  6. Taguchi J, Omoto Y, Uto K, Uekusa H, Niwa T, Hosoya T. Revisiting the Synthetic Utility of 4,5-Dehydro[2.2]paracyclophane. Adv Synth Catal. 2025.01; 367 (2): e202400986 . ( DOI )

  7. Taguchi J, Tokunaga K, Tabuchi H, Nishiyama T, Kii I, Hosoya T. 1,3-Butadiynyl sulfide-based compact trialkyne platform molecule for sequential assembly of three azides. Chem Commun. 2024.12; 60 (98): 14581-14584. ( PubMed, DOI )

  8. Shiino H, Tashiro S, Hashimoto M, Sakata Y, Hosoya T, Endo T, Kojima H, Tamura Y. Chemical inhibition of phosphatidylcholine biogenesis reveals its role in mitochondrial division. iScience. 2024.03; 27 (3): 109189. ( PubMed, DOI )

  9. Watanabe K, Mao Q, Zhang Z, Hata M, Kodera M, Kitagishi H, Niwa T, Hosoya T. Clickable bisreactive small gold nanoclusters for preparing multifunctionalized nanomaterials: application to photouncaging of an anticancer molecule. Chem Sci. 2024.01; 15 (4): 1402-1408. ( PubMed, DOI )

  10. Niwa T, Takimoto T, Sakata Y, Hosoya T. Palladium-Catalyzed ipso-Borylation of Aryl Halides Promoted by Lewis Acid-Mediated Electrophilic Activation of Aryl(halo)palladium(II) Complex. Org Lett. 2023.11; 25 (45): 8173-8177. ( PubMed, DOI )

  11. Taguchi J, Okuyama T, Tomita S, Niwa T, Hosoya T. Synthesis of Multisubstituted Aromatics via 3-Triazenylarynes. Org Lett. 2023.09; 25 (38): 7030-7034. ( PubMed, DOI )

  12. Zhang Z, Niwa T, Watanabe K, Hosoya T. 11C-Cyanation of Aryl Fluorides via Nickel and Lithium Chloride-Mediated C-F Bond Activation. Angew Chem Int Ed Engl. 2023.05; 62 (22): e202302956. ( PubMed, DOI )

  13. Dubol M, Immenschuh J, Jonasson M, Takahashi K, Niwa T, Hosoya T, Roslin S, Wikström J, Antoni G, Watanabe Y, Lubberink M, Biegon A, Sundström-Poromaa I, Comasco E. Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study. Compr Psychiatry. 2023.03; 123 152381. ( PubMed, DOI )

  14. Niwa T, Tahara T, Chase CE, Fang FG, Nakaoka T, Irie S, Hayashinaka E, Wada Y, Mukai H, Masutomi K, Watanabe Y, Cui Y, Hosoya T. Synthesis of 11C-Radiolabeled Eribulin as a Companion Diagnostics PET Tracer for Brain Glioblastoma. Bull Chem Soc Jpn. 2023.03; 96 (3): 283-290. ( DOI )

  15. Tabata S, Minoshima M, Kobayashi A, Matsuzawa T, Hosoya T, Yoshida S. Migrative Thioamination of Aryne Intermediates Generated from o-Iodoaryl Triflates. Synlett. 2023.02; ( DOI )

  16. Sakata Y, Nabekura R, Hazama Y, Hanya M, Nishiyama T, Kii I, Hosoya T. Synthesis of Functionalized Dibenzoazacyclooctynes by a Decomplexation Method for Dibenzo-Fused Cyclooctyne-Cobalt Complexes. Org Lett. 2023.02; 25 (7): 1051-1055. ( PubMed, DOI )

  17. Kobayashi A, Matsuzawa T, Hosoya T, Yoshida S. Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction. RSC Adv. 2023.01; 13 (2): 839-843. ( PubMed, DOI )

  18. Katayama A, Jin Y, Nishiyama Y, Hosoya T, Yokoshima S. Substitution of α-Azido Sulfones with Thiolates to Form α-Azido Sulfides. Org Lett. 2022.10; 24 (40): 7361-7365. ( PubMed, DOI )

  19. Inouye S, Sato J, Sahara-Miura Y, Tomabechi Y, Sumida Y, Sekine S, Shirouzu M, Hosoya T. Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate. PLoS One. 2022.09; 17 (9): e0272992. ( PubMed, DOI )

  20. Watanabe K, Kuratsu A, Hashizume D, Niwa T, Hosoya T. Red light-induced conjugation of amines through amide bond formation triggered via photooxidation of 3-acylindolizines. Commun Chem. 2022.08; 5 (1): 91. ( PubMed, DOI )

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