Published Papers & Misc - HOSOYA Takamitsu

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  1. Uetake Y, Niwa T, Hosoya T. Rhodium-Catalyzed ipso-Borylation of Alkylthioarenes via C-S Bond Cleavage. Org Lett. 2016.06; 18 (11): 2758-2761. ( PubMed, DOI )

  2. Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, Kato-Sumida T, Koike Y, Abe M, Nonaka Y, Ikura T, Ito N, Shibuya H, Hosoya T, Hagiwara M. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016.04; 7 11391. ( PubMed, DOI )

  3. Tomabechi Y, Hosoya T, Ehara H, Sekine S, Shirouzu M, Inouye S. Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine. Biochem Biophys Res Commun. 2016.01; 470 (1): 88-93. ( PubMed, DOI )

  4. Yoshida S, Sugimura Y, Hazama Y, Nishiyama Y, Yano T, Shimizu S, Hosoya T. A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates. Chem Commun. 2015.12; 51 (93): 16613-16616. ( PubMed, DOI )

  5. Yoshida S, Hosoya T. The Renaissance and Bright Future of Synthetic Aryne Chemistry. Chem Lett. 2015.11; 44 (11): 1450-1460. ( DOI )

  6. Niwa T, Ochiai H, Watanabe Y, Hosoya T. Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C-F Bond Functionalizations. J Am Chem Soc. 2015.11; 137 (45): 14313-14318. ( PubMed, DOI )

  7. Yoshida S, Yano T, Misawa Y, Sugimura Y, Igawa K, Shimizu S, Tomooka K, Hosoya T. Direct thioamination of arynes via reaction with sulfilimines and migratory N-arylation. J Am Chem Soc. 2015.11; 137 (44): 14071-14074. ( PubMed, DOI )

  8. Okamoto M, Hidaka A, Toyama M, Hosoya T, Yamamoto M, Hagiwara M, Baba M. Selective inhibition of HIV-1 replication by the CDK9 inhibitor FIT-039. Antiviral Res. 2015.11; 123 1-4. ( PubMed, DOI )

  9. Yoshida S, Shimomori K, Nonaka T, Hosoya T. Facile Synthesis of Diverse Multisubstituted ortho-Silylaryl Triflates via C–H Borylation. Chem Lett. 2015.10; 44 (10): 1324-1326. ( DOI )

  10. Hosoya T, Iimori R, Yoshida S, Sumida Y, Sahara-Miura Y, Sato J, Inouye S. Concise Synthesis of v-Coelenterazines. Org Lett. 2015.08; 17 (15): 3888-3891. ( PubMed, DOI )

  11. Masaki S, Kii I, Sumida Y, Kato-Sumida T, Ogawa Y, Ito N, Nakamura M, Sonamoto R, Kataoka N, Hosoya T, Hagiwara M. Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis. Bioorg Med Chem. 2015.08; 23 (15): 4434-4441. ( PubMed, DOI )

  12. Morooka S, Hoshina M, Kii I, Okabe T, Kojima H, Inoue N, Okuno Y, Denawa M, Yoshida S, Fukuhara J, Ninomiya K, Ikura T, Furuya T, Nagano T, Noda K, Ishida S, Hosoya T, Ito N, Yoshimura N, Hagiwara M. Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice. Mol Pharmacol. 2015.08; 88 (2): 316-325. ( PubMed, DOI )

  13. Sonamoto R, Kii I, Koike Y, Sumida Y, Kato-Sumida T, Okuno Y, Hosoya T, Hagiwara M. Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ. Sci Rep. 2015.08; 5 12728. ( PubMed, DOI )

  14. Yoshida S, Hazama Y, Sumida Y, Yano T, Hosoya T. An Alternative Method for Generating Arynes from ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether. Molecules. 2015.06; 20 (6): 10131-10140. ( PubMed, DOI )

  15. Yoshida S, Uchida K, Hosoya T. Generation of Arynes Using Trimethylsilylmethyl Grignard Reagent for Activation of ortho-Iodoaryl or ortho-Sulfinylaryl Triflates. Chem Lett. 2015.05; 44 (5): 691-693. ( DOI )

  16. Yoshida S, Karaki F, Uchida F, Hosoya T. Generation of cycloheptynes and cyclooctynes via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates. Chem Commun. 2015.05; 51 (42): 8745-8748. ( PubMed, DOI )

  17. Yoshida M, Kataoka N, Miyauchi K, Ohe K, Iida K, Yoshida S, Nojima T, Okuno Y, Onogi H, Usui T, Takeuchi A, Hosoya T, Suzuki T, Hagiwara M. Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia. Proc Natl Acad Sci USA. 2015.03; 112 (9): 2764-2769. ( PubMed, DOI )

  18. Yoshida S, Uchida K, Igawa K, Tomooka K, Hosoya T. An efficient generation method and remarkable reactivities of 3-triflyloxybenzyne. Chem Commun (Camb.). 2014.11; 50 (95): 15059-15062. ( PubMed, DOI )

  19. Sumida Y, Harada R, Kato-Sumida T, Johmoto K, Uekusa H, Hosoya T. Boron-Selective Biaryl Coupling Approach to Versatile Dibenzoxaborins and Application to Concise Synthesis of Defucogilvocarcin M. Org Lett. 2014.11; 16 (23): 6240-6243. ( PubMed, DOI )

  20. Xu F, Peng L, Shinohara K, Morita T, Yoshida S, Hosoya T, Orita A, Otera J. Substituted 5,6,11,12-Tetradehydrodibenzo[a,e]cyclooctenes: Syntheses, Properties, and DFT Studies of Substituted Sondheimer-Wong Diynes. J Org Chem. 2014.11; 79 (23): 11592-11608. ( PubMed, DOI )

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