論文・総説 - 秋山　好光

101. Lu SL, Zhang WC, Akiyama Y, Nomizu T, Yuasa Y. Genomic structure of the transforming growth factor beta type II receptor gene and its mutations in hereditary nonpolyposis colorectal cancers. Cancer Res. 1996.10; 56 (20): 4595-4598. ( PubMed )

102. Hori H, Miyake S, Akiyama Y, Endo M, Yuasa Y. Clonal heterogeneity in human esophageal squamous cell carcinomas on DNA analysis. Jpn J Cancer Res. 1996.09; 87 (9): 923-929. ( PubMed )

103. Akiyama Y, Nakasaki H, Nihei Z, Iwama T, Nomizu T, Utsunomiya J, Yuasa Y. Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers. Jpn J Cancer Res. 1996.06; 87 (6): 595-601. ( PubMed )

104. Lu SL, Akiyama Y, Nagasaki H, Nomizu T, Ikeda E, Baba S, Ushio K, Iwama T, Maruyama K, Yuasa Y. Loss or somatic mutations of hMSH2 occur in hereditary nonpolyposis colorectal cancers with hMSH2 germline mutations. Jpn J Cancer Res. 1996.03; 87 (3): 279-287. ( PubMed )

105. Sasaki A, Nagashima M, Shiseki M, Katai H, Maruyama K, Iwanaga R, Akiyama Y, Yuasa Y, Yokota J. Microsatellite instability in gastric cancer prone families. Cancer Lett. 1996.02; 99 (2): 169-175. ( PubMed )

106. Lu SL, Akiyama Y, Nagasaki H, Saitoh K, Yuasa Y. Mutations of the transforming growth factor-beta type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer. Biochem Biophys Res Commun. 1995.11; 216 (2): 452-457. ( PubMed, DOI )

107. Oto M, Suehiro T, Akiyama Y, Yuasa Y. Microsatellite instability in cancer identified by non-gel sieving capillary electrophoresis. Clin Chem. 1995.03; 41 (3): 482-483. ( PubMed )

108. 秋山好光, 斎藤澄, 大倉康男, 伴慎一, 中村恭一. PCNA発現を指標としたヒト胃癌の増殖動態の研究-画像解析による定量的検討の試み- 胃と腸. 1995.01; 30 (1): 113-119.

109. Wu C, Akiyama Y, Imai K, Miyake S, Nagasaki H, Oto M, Okabe S, Iwama T, Mitamura K, Masumitsu H, et al.. DNA alterations in cells from hereditary non-polyposis colorectal cancer patients. Oncogene. 1994.03; 9 (3): 991-994. ( PubMed )

110. 蒲池厚志、秋山好光、島田周、波多野恵、田中真二. 胆道癌におけるエピゲノム異常とその臨床的意義 胆と膵. 2024.08; 45 (8): 835-843.

111. 波多野恵、秋山好光、島田周、田中真二. 脂肪負荷に対する肝癌の耐性機序 肝胆膵. 2024.04; 88 (4): 459-465.

112. 谷合 智彦, 島田 周, 秋山 好光, 波多野 恵, 田中 真二. MTM/VETCを形成する高悪性度肝細胞癌同種移植モデルの作製とその分子生物学的特徴および癌免疫微小環境の解明. 肝胆膵. 2023.04; 86 (4): 542-543.

113. Ishii Takeshi, Akiyama Yoshimitsu, Shimada Shu, Kabashima Ayano, Asano Daisuke, Watanabe Shuichi, Ishikawa Yoshiya, Ueda Hiroki, Akahoshi Keiichi, Ogawa Kosuke, Ono Hiroaki, Kudo Atsushi, Tanabe Minoru, Tanaka Shinji. Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer CANCER SCIENCE. 2022.11; 114 (2): 463-476. ( PubMed, DOI )

114. Kabashima Ayano, Matsuo Yuki, Ito Saki, Akiyama Yoshimitsu, Ishii Takeshi, Shimada Shu, Masamune Atsushi, Tanabe Minoru, Tanaka Shinji. cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer SCIENTIFIC REPORTS. 2022.06; 12 (1): 10466. ( PubMed, DOI )

115. 安川 紘矢, 秋山 好光, 島田 周, 田中 真二. 【胆道疾患研究最前線】胆道癌の分子生物学的サブタイプと治療戦略 消化器・肝臓内科. 2022.01; 11 (1): 33-42. ( 医中誌 )

116. 谷合 智彦, 秋山 好光, 島田 周, 田中 真二. 【肝内胆管癌を極める】肝内胆管癌の病理　肝内胆管癌の分子生物学的特徴 肝胆膵. 2021.02; 82 (2): 261-268. ( 医中誌 )

117. Akiyama Yoshimitsu, Shimada Shu, Tanabe Minoru, Tanaka Shinji. Loss of ARID1A increases a stemness gene ALDH1A1 expression through histone acetylation change in cholangiocarcinoma CANCER SCIENCE. 2021.02; 112 438.

118. Shimada Shu, Akiyama Yoshimitsu, Tanabe Minoru, Tanaka Shinji. Loss of KDM6A characterizes a poor prognostic subtype of pancreatic cancer and potentiates HDAC inhibitor lethality CANCER SCIENCE. 2021.02; 112 491.

119. Seol Hyang Sook, Akiyama Yoshimitsu, Lee San-Eun, Shimada Shu, Jang Se Jin. Loss of miR-100 and miR-125b results in cancer stem cell properties through IGF2 upregulation in hepatocellular carcinoma SCIENTIFIC REPORTS. 2020.12; 10 (1): 21412. ( PubMed, DOI )

120. 秋山 好光. 【エピジェネティクスと疾患】ヒストン修飾 医学のあゆみ. 2020.01; 272 (1): 10-16. ( 医中誌 )