論文・総説 - 秋山　好光

分割表示  133 件中 61 - 80 件目  ／  全件表示 >>

  1. Yuasa Y, Nagasaki H, Akiyama Y, Sakai H, Nakajima T, Ohkura Y, Takizawa T, Koike M, Tani M, Iwai T, Sugihara K, Imai K, Nakachi K. Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients. Carcinogenesis. 2005.01; 26 (1): 193-200. ( PubMed, DOI )

  2. Jinawath A, Miyake S, Yanagisawa Y, Akiyama Y, Yuasa Y. Transcriptional regulation of the human DNA methyltransferase 3A and 3B genes by Sp3 and Sp1 zinc finger proteins. Biochem J. 2005.01; 385 (Pt 2): 557-564. ( PubMed, DOI )

  3. Guo M, Akiyama Y, House MG, Hooker CM, Heath E, Gabrielson E, Yang SC, Han Y, Baylin SB, Herman JG, Brock MV. Hypermethylation of the GATA genes in lung cancer. Clin Cancer Res. 2004.12; 10 (23): 7917-7924. ( PubMed, DOI )

  4. Ren CY, Akiyama Y, Miyake S, Yuasa Y. Transcription factor GATA-5 selectively up-regulates mucin gene expression. J Cancer Res Clin Oncol. 2004.05; 130 (5): 245-252. ( PubMed, DOI )

  5. Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet. 2004.04; 36 (4): 417-422. ( PubMed, DOI )

  6. Sakai H, Eishi Y, Li XL, Akiyama Y, Miyake S, Takizawa T, Konishi N, Tatematsu M, Koike M, Yuasa Y. PDX1 homeobox protein expression in pseudopyloric glands and gastric carcinomas. Gut. 2004.03; 53 (3): 323-330. ( PubMed )

  7. Wen XZ, Miyake S, Akiyama Y, Yuasa Y. BMP-2 modulates the proliferation and differentiation of normal and cancerous gastric cells. Biochem Biophys Res Commun. 2004.03; 316 (1): 100-106. ( PubMed, DOI )

  8. Douglas DB, Akiyama Y, Carraway H, Belinsky SA, Esteller M, Gabrielson E, Weitzman S, Williams T, Herman JG, Baylin SB. Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Res. 2004.03; 64 (5): 1611-1620. ( PubMed )

  9. Li XL, Eishi Y, Bai YQ, Sakai H, Akiyama Y, Tani M, Takizawa T, Koike M, Yuasa Y. Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma. Int J Oncol. 2004.02; 24 (2): 257-263. ( PubMed )

  10. Akiyama Y, Watkins N, Suzuki H, Jair KW, van Engeland M, Esteller M, Sakai H, Ren CY, Yuasa Y, Herman JG, Baylin SB. GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer. Mol Cell Biol. 2003.12; 23 (23): 8429-8439. ( PubMed )

  11. Brock MV, Gou M, Akiyama Y, Muller A, Wu TT, Montgomery E, Deasel M, Germonpre P, Rubinson L, Heitmiller RF, Yang SC, Forastiere AA, Baylin SB, Herman JG. Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma. Clin Cancer Res. 2003.08; 9 (8): 2912-2919. ( PubMed )

  12. Bai YQ, Yamamoto H, Akiyama Y, Tanaka H, Takizawa T, Koike M, Kenji Yagi O, Saitoh K, Takeshita K, Iwai T, Yuasa Y. Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach. Cancer Lett. 2002.02; 176 (1): 47-55. ( PubMed )

  13. Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedenfalk I, Godwin AK, Trojan J, Vaurs-Barriere C, Bignon YJ, Ramus S, Benitez J, Caldes T, Akiyama Y, Yuasa Y, Launonen V, Canal MJ, Rodriguez R, Capella G, Peinado MA, Borg A, Aaltonen LA, Ponder BA, Baylin SB, Herman JG. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum Mol Genet. 2001.12; 10 (26): 3001-3007. ( PubMed )

  14. Nakajima T, Akiyama Y, Shiraishi J, Arai T, Yanagisawa Y, Ara M, Fukuda Y, Sawabe M, Saitoh K, Kamiyama R, Hirokawa K, Yuasa Y. Age-related hypermethylation of the hMLH1 promoter in gastric cancers. Int J Cancer. 2001.10; 94 (2): 208-211. ( PubMed )

  15. Akiyama Y, Nagasaki H, Nakajima T, Sakai H, Nomizu T, Yuasa Y. Infrequent frameshift mutations in the simple repeat sequences of hMLH3 in hereditary nonpolyposis colorectal cancers. Jpn J Clin Oncol. 2001.02; 31 (2): 61-64. ( PubMed )

  16. Sato Y, Akiyama Y, Tanizawa T, Shibata T, Saito K, Mori S, Kamiyama R, Yuasa Y. Molecular characterization of the genomic breakpoint junction in the t(11;18) (q21;q21) translocation of a gastric MALT lymphoma. Biochem Biophys Res Commun. 2001.01; 280 (1): 301-306. ( PubMed, DOI )

  17. Akiyama Y, Nagasaki H, Yagi KO, Nomizu T, Yuasa Y. Beta-catenin and adenomatous polyposis coli (APC) mutations in adenomas from hereditary non-polyposis colorectal cancer patients. Cancer Lett. 2000.09; 157 (2): 185-191. ( PubMed )

  18. Iida S, Akiyama Y, Nakajima T, Ichikawa W, Nihei Z, Sugihara K, Yuasa Y. Alterations and hypermethylation of the p14(ARF) gene in gastric cancer. Int J Cancer. 2000.09; 87 (5): 654-658. ( PubMed )

  19. Bai Y, Akiyama Y, Nagasaki H, Yagi OK, Kikuchi Y, Saito N, Takeshita K, Iwai T, Yuasa Y. Distinct expression of CDX2 and GATA4/5, development-related genes, in human gastric cancer cell lines. Mol Carcinog. 2000.07; 28 (3): 184-188. ( PubMed )

  20. Furihata M, Shuin T, Takeuchi T, Sonobe H, Ohtsuki Y, Akiyama Y, Yuasa Y. Missense mutation of the hMSH6 and p53 genes in sporadic urothelial transitional cell carcinoma. Int J Oncol. 2000.03; 16 (3): 491-496. ( PubMed )

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