論文・総説 - 東田　修二

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  1. Okuhashi Y, Itoh M, Arai A, Nara N, Tohda S. Gamma-secretase inhibitors induce erythroid differentiation in erythroid leukemia cell lines. Anticancer Res. 2010.10; 30 (10): 4071-4074. ( PubMed )

  2. Ishigaki T, Sasaki K, Watanabe K, Nakamura N, Toyota S, Kobayashi H, Tohda S. Amplification of IGH/CCND1 fusion gene in a primary plasma cell leukemia case. Cancer Genet Cytogenet. 2010.08; 201 (1): 62-65. ( PubMed, DOI )

  3. Okuhashi Y, Nara N, Tohda S. Effects of gamma-secretase inhibitors on the growth of leukemia cells. Anticancer Res. 2010.02; 30 (2): 495-498. ( PubMed )

  4. Kawahara T, Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Nara N, Tohda S. Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells. Anticancer Res. 2009.11; 29 (11): 4629-4632. ( PubMed )

  5. Fu L, Katsube K, Tohda S. Transition of cleaved Notch1 and gene expression changes in myeloblastic leukemia cells stimulated with notch ligands. Anticancer Res. 2009.10; 29 (10): 3967-3970. ( PubMed )

  6. Itoh M, Fu L, Tohda S. NF-kappaB activation induced by Notch ligand stimulation in acute myeloid leukemia cells. Oncol Rep. 2009.09; 22 (3): 631-634. ( PubMed )

  7. Kawaguchi-Ihara N, Murohashi I, Nara N, Tohda S. Promotion of the self-renewal capacity of human acute leukemia cells by Wnt3A. Anticancer Res. 2008.09; 28 (5A): 2701-2704. ( PubMed )

  8. Fu L, Nara N, Tohda S. Involvement of Notch signaling in myelodysplastic syndrome. Leuk Res. 2007.08; 31 (8): 1160-1161. ( PubMed, DOI )

  9. Kogoshi H, Sato T, Koyama T, Nara N, Tohda S. Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells. Oncol Rep. 2007.07; 18 (1): 77-80. ( PubMed )

  10. Fu L, Kogoshi H, Nara N, Tohda S. NOTCH1 mutations are rare in acute myeloid leukemia. Leuk Lymphoma. 2006.11; 47 (11): 2400-2403. ( PubMed, DOI )

  11. Kogoshi H, Tohda S, Fu L, Koyama T, Nara N. Effect of notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells. Oncol Rep. 2005.09; 14 (3): 723-726. ( PubMed )

  12. Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N. The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells. Leuk Res. 2005.02; 29 (2): 197-203. ( PubMed, DOI )

  13. Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N. The Notch ligand, Delta-1, reduces TNF-alpha-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells. Int J Mol Med. 2004.11; 14 (5): 861-866. ( PubMed )

  14. Murata-Ohsawa M, Tohda S, Nara N. Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines. Int J Mol Med. 2004.08; 14 (2): 223-226. ( PubMed )

  15. Saito R, Takahashi R, Sawabe E, Koyano S, Takahashi Y, Shima M, Ushizawa H, Fujie T, Tosaka N, Kato Y, Moriya K, Tohda S, Tojo N, Koike R, Kubota T. First Report of KPC-2 Carbapenemase-Producing Klebsiella pneumoniae in Japan. Antimicrob Agents Chemother. 2014.05; 58 (5): 2961-2963. ( PubMed, DOI )

  16. Murata-Ohsawa M, Tohda S, Sakano S, Nara N. The Notch ligand, Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells. Int J Mol Med. 2004.03; 13 (3): 419-423. ( PubMed )

  17. Nagao T, Kurosu T, Umezawa Y, Nogami A, Oshikawa G, Tohda S, Yamamoto M, Miura O. Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera. PLoS ONE. 2014; 9 (1): e84746. ( PubMed, DOI )

  18. Siegers GM, Dhamko H, Wang XH, Mathieson AM, Kosaka Y, Felizardo TC, Medin JA, Tohda S, Schueler J, Fisch P, Keating A. Human Vδ1 γδ T cells expanded from peripheral blood exhibit specific cytotoxicity against B-cell chronic lymphocytic leukemia-derived cells. Cytotherapy. 2011.07; 13 (6): 753-764. ( PubMed, DOI )

  19. Nara N, Suzuki T, Tohda S. The current medical education system in the world. J Med Dent Sci. 2011; 58 (2): 79-83. ( PubMed )

  20. Nara N, Beppu M, Tohda S, Suzuki T. The introduction and effectiveness of simulation-based learning in medical education. Intern Med. 2009; 48 (17): 1515-1519. ( PubMed )

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