Published Papers & Misc - SASAKI Takehiko

41. Marc C Liggins, Jessica L Flesher, Sohail Jahid, Priya Vasudeva, Victoria Eby, Shunsuke Takasuga, Junko Sasaki, Takehiko Sasaki, Raymond E Boissy, Anand K Ganesan. PIKfyve regulates melanosome biogenesis. PLoS Genet.. 2018; 14 (3): e1007290. ( PubMed, DOI )

42. Mingguo Huang, Shintaro Narita, Takamitsu Inoue, Atsushi Koizumi, Mitsuru Saito, Hiroshi Tsuruta, Kazuyuki Numakura, Shigeru Satoh, Hiroshi Nanjo, Takehiko Sasaki, Tomonori Habuchi. Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production. Oncotarget. 2017.12; 8 (67): 111780-111794. ( PubMed, DOI )

43. Mouhannad Malek, Anna Kielkowska, Tamara Chessa, Karen E Anderson, David Barneda, Pınar Pir, Hiroki Nakanishi, Satoshi Eguchi, Atsushi Koizumi, Junko Sasaki, Véronique Juvin, Vladimir Y Kiselev, Izabella Niewczas, Alexander Gray, Alexandre Valayer, Dominik Spensberger, Marine Imbert, Sergio Felisbino, Tomonori Habuchi, Soren Beinke, Sabina Cosulich, Nicolas Le Novère, Takehiko Sasaki, Jonathan Clark, Phillip T Hawkins, Len R Stephens. PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K. Mol. Cell. 2017.11; 68 (3): 566-580.e10. ( PubMed, DOI )

44. 阿部 史人, 中西 広樹, 北舘 明宏, 池田 翔, 亀岡 吉弘, 高橋 直人, 佐々木 雄彦, 田川 博之. 悪性リンパ腫におけるイノシトールリン脂質プロファイル 日本癌学会総会記事. 2017.09; 76回 P-2236. ( ichushi )

45. Tagawa Hiroyuki, Abe Fumito, Nakanishi Hiroki, Kitadate Akihiro, Ikeda Sho, Takahashi Naoto, Sasaki Takehiko. 脂質定量解析による悪性リンパ腫の新たな診断マーカーの同定(Phosphatidylinositol phosphates profile reveals novel diagnostic marker(s) in malignant lymphoma) 臨床血液. 2017.09; 58 (9): 1742. ( ichushi )

46. Hideo Shindou, Hideto Koso, Junko Sasaki, Hiroki Nakanishi, Hiroshi Sagara, Koh M Nakagawa, Yoshikazu Takahashi, Daisuke Hishikawa, Yoshiko Iizuka-Hishikawa, Fuyuki Tokumasu, Hiroshi Noguchi, Sumiko Watanabe, Takehiko Sasaki, Takao Shimizu. Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells. J. Biol. Chem.. 2017.07; 292 (29): 12054-12064. ( PubMed, DOI )

47. Yoshiko Iizuka-Hishikawa, Daisuke Hishikawa, Junko Sasaki, Keiyo Takubo, Motohito Goto, Katsuyuki Nagata, Hiroki Nakanishi, Hideo Shindou, Tadashi Okamura, Chizuru Ito, Kiyotaka Toshimori, Takehiko Sasaki, Takao Shimizu. Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis. J. Biol. Chem.. 2017.07; 292 (29): 12065-12076. ( PubMed, DOI )

48. Otsubo K., Goto H., Nishio M., Kawamura K., Yanagi S., Nishie W., Sasaki T., Maehama T., Nishina H., Mimori K., Nakano T., Shimizu H., Mak T. W., Nakao K., Nakanishi Y., Suzuki A.. MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation ONCOGENE. 2017.07; 36 (29): 4201-4211. ( PubMed, DOI )

49. 黄 明国, 小泉 淳, 井上 高光, 成田 伸太郎, 斉藤 満, 佐藤 滋, 南條 博, 佐々木 雄彦, 羽渕 友則. 高脂肪食下前立腺間質　癌微小環境の活性化と前立腺癌進展における脂肪酸結合分子4(FABP4)の役割 日本泌尿器科学会総会. 2017.04; 105回 OP41-4. ( ichushi )

50. Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Masaki N, Akatsu H, Hashizume Y, Yamamoto S, Sato S, Sasaki T, Setou M, Yabe H. Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia. Scientific reports. 2017.03; 7 45050. ( PubMed, DOI )

51. Hirotaka Kimura, Satoshi Eguchi, Junko Sasaki, Keiji Kuba, Hiroki Nakanishi, Shunsuke Takasuga, Masakazu Yamazaki, Akiteru Goto, Hiroyuki Watanabe, Hiroshi Itoh, Yumiko Imai, Akira Suzuki, Noboru Mizushima, Takehiko Sasaki. Vps34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy. JCI Insight. 2017.01; 2 (1): e89462. ( PubMed, DOI )

52. Shin Morioka, Kiyomi Nigorikawa, Junko Sasaki, Kaoru Hazeki, Yoshihiro Kasuu, Takehiko Sasaki, Osamu Hazeki. Myeloid cell-specific inositol polyphosphate-4-phosphatase type I knockout mice impair bacteria clearance in a murine peritonitis model INNATE IMMUNITY. 2016.08; 22 (6): 444-451. ( PubMed, DOI )

53. Localizing the lipid products of PI3Kγ in neutrophils. Advances in biological regulation. 2016.01; 60 36-45. ( PubMed, DOI )

54. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 2016.01; 113 (1): E71-E80. ( PubMed, DOI )

55. Kiyomi Nigorikawa, Kaoru Hazeki, Junko Sasaki, Yumio Omori, Mikiko Miyake, Shin Morioka, Ying Guo, Takehiko Sasaki, Osamu Hazeki. Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns (3,4)P-2 PLOS ONE. 2015.11; 10 (11): ( PubMed, DOI )

56. Chen Li Chew, Andrea Lunardi, Federico Gulluni, Daniel T Ruan, Ming Chen, Leonardo Salmena, Michiya Nishino, Antonella Papa, Christopher Ng, Jacqueline Fung, John G Clohessy, Junko Sasaki, Takehiko Sasaki, Roderick T Bronson, Emilio Hirsch, Pier Paolo Pandolfi. In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes. Cancer Discov. 2015.07; 5 (7): 740-751. ( PubMed, DOI )

57. Laura R H Ip, George Poulogiannis, Felipe Cia Viciano, Junko Sasaki, Satoshi Kofuji, Victoria J Spanswick, Daniel Hochhauser, John A Hartley, Takehiko Sasaki, Christina A Gewinner. Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment. Oncotarget. 2015.04; 6 (12): 10548-10562. ( PubMed, DOI )

58. Gerald R V Hammond, Shunsuke Takasuga, Takehiko Sasaki, Tamas Balla. The ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells. PLoS ONE. 2015; 10 (10): e0139957. ( PubMed, DOI )

59. Y. Fujioka, M. Tsuda, A. Nanbo, T. Hattori, J. Sasaki, T. Sasaki, T. Miyazaki, Y. Ohba. Calcium signaling mediated influenza virus entry into host cells. MOLECULAR BIOLOGY OF THE CELL. 2014.12; 25

60. Y. Fujioka, M. Tsuda, A. Nanbo, T. Hattori, J. Sasaki, T. Sasaki, T. Miyazaki, Y. Ohba. Calcium signaling mediated influenza virus entry into host cells. MOLECULAR BIOLOGY OF THE CELL. 2014.12; 25