論文・総説 - 永田　哲也

81. Aoki Y, Yokota T, Nagata T, Nakamura A, Tanihata J, Saito T, Duguez SM, Nagaraju K, Hoffman EP, Partridge T, Takeda S. Bodywide skipping of exons 45-55 in dystrophic mdx52 mice by systemic antisense delivery. Proceedings of the National Academy of Sciences of the United States of America. 2012.08; 109 (34): 13763-13768. ( PubMed, DOI )

82. Nagata T, Takeda S. Antisense oligos for muscular dystrophy. Rinsho shinkeigaku = Clinical neurology. 2010.11; 50 (11): 843. ( PubMed )

83. Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda S. In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse. Molecular therapy : the journal of the American Society of Gene Therapy. 2010.11; 18 (11): 1995-2005. ( PubMed, DOI )

84. Hoang T, Choi DK, Nagai M, Wu DC, Nagata T, Prou D, Wilson GL, Vila M, Jackson-Lewis V, Dawson VL, Dawson TM, Chesselet MF, Przedborski S. Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease. Free radical biology & medicine. 2009.10; 47 (7): 1049-1056. ( PubMed, DOI )

85. Ohta Y, Kamiya T, Nagai M, Nagata T, Morimoto N, Miyazaki K, Murakami T, Kurata T, Takehisa Y, Ikeda Y, Asoh S, Ohta S, Abe K. Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis. Journal of neuroscience research. 2008.10; 86 (13): 3028-3037. ( PubMed, DOI )

86. Nagata T, Ilieva H, Murakami T, Shiote M, Narai H, Ohta Y, Hayashi T, Shoji M, Abe K. Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis. Neurological research. 2007.12; 29 (8): 767-771. ( PubMed, DOI )

87. Nagata T, Nagano I, Shiote M, Narai H, Murakami T, Hayashi T, Shoji M, Abe K. Elevation of MCP-1 and MCP-1/VEGF ratio in cerebrospinal fluid of amyotrophic lateral sclerosis patients. Neurological research. 2007.12; 29 (8): 772-776. ( PubMed, DOI )

88. Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nature neuroscience. 2007.05; 10 (5): 615-622. ( PubMed, DOI )

89. Hirano M, Yamamoto A, Mori T, Lan L, Iwamoto TA, Aoki M, Shimada K, Furiya Y, Kariya S, Asai H, Yasui A, Nishiwaki T, Imoto K, Kobayashi N, Kiriyama T, Nagata T, Konishi N, Itoyama Y, Ueno S. DNA single-strand break repair is impaired in aprataxin-related ataxia. Annals of neurology. 2007.02; 61 (2): 162-174. ( PubMed, DOI )

90. Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K. Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene. Journal of neuroscience research. 2006.10; 84 (5): 980-992. ( PubMed, DOI )

91. Iwai M, Ikeda T, Hayashi T, Sato K, Nagata T, Nagano I, Shoji M, Ikenoue T, Abe K. Temporal profile of neural stem cell proliferation in the subventricular zone after ischemia/hypoxia in the neonatal rat brain. Neurological research. 2006.06; 28 (4): 461-468. ( PubMed, DOI )

92. Suzuki N, Aoki M, Mizuno H, Onodera Y, Takahashi T, Nagata T, Tateyama M, Itoyama Y. Late-onset distal myopathy with rimmed vacuoles without mutation in the GNE or dysferlin genes. Muscle & nerve. 2005.12; 32 (6): 812-814. ( PubMed, DOI )

93. Narai H, Nagano I, Ilieva H, Shiote M, Nagata T, Hayashi T, Shoji M, Abe K. Prevention of spinal motor neuron death by insulin-like growth factor-1 associating with the signal transduction systems in SODG93A transgenic mice. Journal of neuroscience research. 2005.11; 82 (4): 452-457. ( PubMed, DOI )

94. Matsubara E, Nagata T, Kageyama Y, Shiote M, Namba R, Nagano I, Shoji M, Abe K. Unique cerebellar-cerebral form of autosomal recessive ataxia. The Tohoku journal of experimental medicine. 2005.09; 207 (1): 81-85. ( PubMed )

95. Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K. Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia. Neuroscience. 2005.01; 132 (1): 175-182. ( PubMed, DOI )

96. Murakami T, Ilieva H, Shiote M, Nagata T, Nagano I, Shoji M, Abe K. Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene. Brain research. 2003.11; 989 (2): 231-237. ( PubMed )

97. Sakurai M, Nagata T, Abe K, Horinouchi T, Itoyama Y, Tabayashi K. Survival and death-promoting events after transient spinal cord ischemia in rabbits: induction of Akt and caspase3 in motor neurons. The Journal of thoracic and cardiovascular surgery. 2003.02; 125 (2): 370-377. ( PubMed, DOI )

98. Sakurai M, Nagata T, Abe K, Horinouchi T, Itoyama Y, Tabayashi K. Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits. Journal of vascular surgery. 2003.02; 37 (2): 446-452. ( PubMed, DOI )

99. Nishino I, Noguchi S, Murayama K, Driss A, Sugie K, Oya Y, Nagata T, Chida K, Takahashi T, Takusa Y, Ohi T, Nishimiya J, Sunohara N, Ciafaloni E, Kawai M, Aoki M, Nonaka I. Distal myopathy with rimmed vacuoles is allelic to hereditary inclusion body myopathy. Neurology. 2002.12; 59 (11): 1689-1693. ( PubMed )

100. Moreira MC, Barbot C, Tachi N, Kozuka N, Uchida E, Gibson T, Mendonça P, Costa M, Barros J, Yanagisawa T, Watanabe M, Ikeda Y, Aoki M, Nagata T, Coutinho P, Sequeiros J, Koenig M. The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nature genetics. 2001.10; 29 (2): 189-193. ( PubMed, DOI )