論文・総説 - 大川　龍之介

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  1. Yoshikazu Ono, Makoto Kurano, Ryunosuke Ohkawa, Hiromitsu Yokota, Koji Igarashi, Junken Aoki, Minoru Tozuka, Yutaka Yatomi. Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration. Lipids Health Dis. 2013; 12 20. ( PubMed, DOI )

  2. Ryunosuke Ohkawa, Tatsuya Kishimoto, Makoto Kurano, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Mika Nagasaki, Kansei Uno, Naoto Hayashi, Noboru Sakai, Naoto Matsuyama, Takahiro Nojiri, Kazuhiro Nakamura, Shigeo Okubo, Hiromitsu Yokota, Hitoshi Ikeda, Yutaka Yatomi. Development of an enzymatic assay for sphingomyelin with rapid and automatable performances: Analysis in healthy subjects and coronary heart disease patients. Clin. Biochem.. 2012.11; 45 (16-17): 1463-1470. ( PubMed, DOI )

  3. Tomotaka Dohi, Katsumi Miyauchi, Ryunosuke Ohkawa, Kazuhiro Nakamura, Shuta Thuboi, Manabu Ogita, Tadashi Miyazaki, Akihisa Nishino, Ken Yokoyama, Takeshi Kurata, Yutaka Yatomi, Hiroyuki Daida. Higher lipoprotein-associated phospholipase A2 levels are associated with coronary atherosclerosis documented by coronary angiography. Ann. Clin. Biochem.. 2012.11; 49 (Pt 6): 527-533. ( PubMed, DOI )

  4. Kazuhiro Nakamura, Koji Igarashi, Ryunosuke Ohkawa, Hiromitsu Yokota, Akiko Masuda, Shunsuke Nakagawa, Tetsu Yano, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi. Serum autotaxin is not a useful biomarker for ovarian cancer. Lipids. 2012.09; 47 (9): 927-930. ( PubMed, DOI )

  5. Yoko Soroida, Ryunosuke Ohkawa, Hayato Nakagawa, Yumiko Satoh, Haruhiko Yoshida, Hiroto Kinoshita, Ryosuke Tateishi, Ryota Masuzaki, Kenichiro Enooku, Shuichiro Shiina, Takahisa Sato, Shuntaro Obi, Tadashi Hoshino, Ritsuko Nagatomo, Shigeo Okubo, Hiromitsu Yokota, Kazuhiko Koike, Yutaka Yatomi, Hitoshi Ikeda. Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence. J. Hepatol.. 2012.08; 57 (2): 330-336. ( PubMed, DOI )

  6. Tomonori Sugiura, Yasuaki Dohi, Sumiyo Yamashita, Nobuyuki Ohte, Shiori Ito, Soichiro Iwaki, Yuji Hirowatari, Ryunosuke Ohkawa, Yuko Mishima, Yutaka Yatomi, Genjiro Kimura, Satoshi Fujii. Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis. Coron. Artery Dis.. 2012.06; 23 (4): 234-238. ( PubMed, DOI )

  7. Tomotaka Dohi, Katsumi Miyauchi, Ryunosuke Ohkawa, Kazuhiro Nakamura, Tatsuya Kishimoto, Tadashi Miyazaki, Akihisa Nishino, Naohisa Nakajima, Kenji Yaginuma, Hiroshi Tamura, Takahiko Kojima, Ken Yokoyama, Takeshi Kurata, Kazunori Shimada, Yutaka Yatomi, Hiroyuki Daida. Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome. Clin. Chim. Acta. 2012.01; 413 (1-2): 207-212. ( PubMed, DOI )

  8. Tomotaka Dohi, Katsumi Miyauchi, Shinya Okazaki, Takayuki Yokoyama, Ryunosuke Ohkawa, Kazuhiro Nakamura, Naotake Yanagisawa, Shuta Tsuboi, Manabu Ogita, Ken Yokoyama, Takeshi Kurata, Yutaka Yatomi, Hiroyuki Daida. Decreased circulating lipoprotein-associated phospholipase A2 levels are associated with coronary plaque regression in patients with acute coronary syndrome. Atherosclerosis. 2011.12; 219 (2): 907-912. ( PubMed, DOI )

  9. Akiko Masuda, Tomoyuki Fujii, Yuki Iwasawa, Kazuhiro Nakamura, Ryunosuke Ohkawa, Koji Igarashi, Shinichi Okudaira, Hitoshi Ikeda, Shiro Kozuma, Junken Aoki, Yutaka Yatomi. Serum autotaxin measurements in pregnant women: application for the differentiation of normal pregnancy and pregnancy-induced hypertension. Clin. Chim. Acta. 2011.10; 412 (21-22): 1944-1950. ( PubMed, DOI )

  10. Hayato Nakagawa, Hitoshi Ikeda, Kazuhiro Nakamura, Ryunosuke Ohkawa, Ryota Masuzaki, Ryosuke Tateishi, Haruhiko Yoshida, Naoko Watanabe, Kazuaki Tejima, Yukio Kume, Tomomi Iwai, Atsushi Suzuki, Tomoaki Tomiya, Yukiko Inoue, Takako Nishikawa, Natsuko Ohtomo, Yasushi Tanoue, Masao Omata, Koji Igarashi, Junken Aoki, Kazuhiko Koike, Yutaka Yatomi. Autotaxin as a novel serum marker of liver fibrosis. Clin. Chim. Acta. 2011.06; 412 (13-14): 1201-1206. ( PubMed, DOI )

  11. Kazuhiro Nakamura, Koji Igarashi, Ryunosuke Ohkawa, Naoya Saiki, Mika Nagasaki, Kansei Uno, Naoto Hayashi, Tetsuji Sawada, Kenichi Syukuya, Hiromitsu Yokota, Hiroyuki Arai, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi. A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A(1) in human serum samples. Clin. Chim. Acta. 2010.08; 411 (15-16): 1090-1094. ( PubMed, DOI )

  12. Hitoshi Ikeda, Ryunosuke Ohkawa, Naoko Watanabe, Kazuhiro Nakamura, Yukio Kume, Hayato Nakagawa, Haruhiko Yoshida, Shigeo Okubo, Hiromitsu Yokota, Tomoaki Tomiya, Yukiko Inoue, Takako Nishikawa, Natsuko Ohtomo, Yasushi Tanoue, Kazuhiko Koike, Yutaka Yatomi. Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C. Clin. Chim. Acta. 2010.05; 411 (9-10): 765-770. ( PubMed, DOI )

  13. Xun Qi, Yasuo Okamoto, Tomomi Murakawa, Fei Wang, Osamu Oyama, Ryunosuke Ohkawa, Kazuaki Yoshioka, Wa Du, Naotoshi Sugimoto, Yutaka Yatomi, Noriko Takuwa, Yoh Takuwa. Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice. Eur. J. Pharmacol.. 2010.05; 634 (1-3): 121-131. ( PubMed, DOI )

  14. Toshiyuki Imasawa, Hiroshi Kitamura, Ryunosuke Ohkawa, Yumiko Satoh, Akiko Miyashita, Yutaka Yatomi. Unbalanced expression of sphingosine 1-phosphate receptors in diabetic nephropathy. Exp. Toxicol. Pathol.. 2010.01; 62 (1): 53-60. ( PubMed, DOI )

  15. 西村 智，長崎 実佳，中村 和宏，大川 龍之介，田嶋 美智子，良永 千穂，宇野 漢成，真鍋 一郎，永井 良三，林 直人，矢冨 裕. 血清リン脂質・生合成系を用いた新規メタボリックシンドロームマーカーの探索 脂質生化学研究. 2010; 52 237-238.

  16. Harumasa Nakazawa, Hiroaki Ohnishi, Hitoshi Okazaki, Shiho Hashimoto, Hajime Hotta, Takashi Watanabe, Ryunosuke Ohkawa, Yutaka Yatomi, Kazunori Nakajima, Yasuhide Iwao, Shigeru Takamoto, Masaru Shimizu, Takehiko Iijima. Impact of fresh-frozen plasma from male-only donors versus mixed-sex donors on postoperative respiratory function in surgical patients: a prospective case-controlled study. Transfusion. 2009.11; 49 (11): 2434-2441. ( PubMed, DOI )

  17. Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Hitoshi Ikeda, Yutaka Yatomi, Koji Igarashi, Kazufumi Ide, Tatsuya Kishimoto, Akiko Masuda, Tomotaka Yamamoto, Shoji Tsuji, Nobuhito Saito, Mineo Kurokawa, Shinichi Okudaira, Junken Aoki. Autotaxin enzyme immunoassay in human cerebrospinal fluid samples. Clin. Chim. Acta. 2009.07; 405 (1-2): 160-162. ( PubMed, DOI )

  18. 西村 智，長崎 実佳，中村 和宏，大川 龍之介，田嶋 美智子，若林 香織，宇野 漢成，真鍋 一郎，永井 良三，林 直人，矢冨 裕. 血清リン脂質・生合成系の変化は加齢・慢性炎症に伴うメタボリックシンドロームの発症を規定する 脂質生化学研究. 2009; 51 298-299.

  19. Atsushi Kimura, Tsukasa Ohmori, Yuji Kashiwakura, Ryunosuke Ohkawa, Seiji Madoiwa, Jun Mimuro, Kuniko Shimazaki, Yuichi Hoshino, Yutaka Yatomi, Yoichi Sakata. Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain. Stroke. 2008.12; 39 (12): 3411-3417. ( PubMed, DOI )

  20. Akiko Masuda, Kazuhiro Nakamura, Koji Izutsu, Koji Igarashi, Ryunosuke Ohkawa, Masahiro Jona, Katsumi Higashi, Hiromitsu Yokota, Shinichi Okudaira, Tatsuya Kishimoto, Takuro Watanabe, Yukako Koike, Hitoshi Ikeda, Yasushi Kozai, Mineo Kurokawa, Junken Aoki, Yutaka Yatomi. Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma. Br. J. Haematol.. 2008.10; 143 (1): 60-70. ( PubMed, DOI )

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