論文・総説 - 大島　茂

41. Akihiro Araki, Shinji Suzuki, Kiichiro Tsuchiya, Shigeru Oshima, Eriko Okada, Mamoru Watanabe. Modified single-operator method for double-balloon endoscopy. Dig Endosc. 2012.11; 24 (6): 470-474. ( PubMed, DOI )

42. Akihiro Araki, Kiichiro Tsuchiya, Shigeru Oshima, Eriko Okada, Shinji Suzuki, Junko Morio Akiyama, Toshimitsu Fujii, Ryuichi Okamoto, Mamoru Watanabe. Endoscopic ultrasound with double-balloon endoscopy for the diagnosis of inverted Meckel's diverticulum: a case report. J Med Case Rep. 2012.09; 6 328. ( PubMed, DOI )

43. Hammer GE, Turer EE, Taylor KE, Fang CJ, Advincula R, Oshima S, Barrera J, Huang EJ, Hou B, Malynn BA, Reizis B, Defranco A, Criswell LA, Nakamura MC, Ma A. Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. Nat Immunol. 2011.10; 12 (12): 1184-1193. ( PubMed, DOI )

44. Akihiro Araki, Kiichiro Tsuchiya, Eriko Okada, Shinji Suzuki, Shigeru Oshima, Sanae Yoshioka, Atsushi Yoshioka, Takanori Kanai, Mamoru Watanabe. Single-operator double-balloon endoscopy (DBE) is as effective as dual-operator DBE. J. Gastroenterol. Hepatol.. 2009.05; 24 (5): 770-775. ( PubMed, DOI )

45. Michio Onizawa, Takashi Nagaishi, Takanori Kanai, Ken-ichi Nagano, Shigeru Oshima, Yasuhiro Nemoto, Atsushi Yoshioka, Teruji Totsuka, Ryuichi Okamoto, Tetsuya Nakamura, Naoya Sakamoto, Kiichiro Tsuchiya, Kazuhiro Aoki, Keiichi Ohya, Hideo Yagita, Mamoru Watanabe. Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis. Am. J. Physiol. Gastrointest. Liver Physiol.. 2009.04; 296 (4): G850-G859. ( PubMed, DOI )

46. Oshima S, Turer EE, Callahan JA, Chai S, Advincula R, Barrera J, Shifrin N, Lee B, Benedict Yen TS, Yen B, Woo T, Malynn BA, Ma A. ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development. Nature. 2009.02; 457 (7231): 906-909. ( PubMed, DOI )

47. A Araki, K Tsuchiya, E Okada, S Suzuki, S Oshima, R Okamoto, T Kanai, M Watanabe. Single-operator method for double-balloon endoscopy: a pilot study. Endoscopy. 2008.11; 40 (11): 936-938. ( PubMed, DOI )

48. Atsushi Yoshioka, Ryuichi Okamoto, Shigeru Oshima, Junko Akiyama, Kiichiro Tsuchiya, Tetsuya Nakamura, Takanori Kanai, Mamoru Watanabe. Flagellin stimulation suppresses IL-7 secretion of intestinal epithelial cells. Cytokine. 2008.10; 44 (1): 57-64. ( PubMed, DOI )

49. R Fujii, T Kanai, Y Nemoto, S Makita, S Oshima, R Okamoto, K Tsuchiya, T Totsuka, M Watanabe. FTY720 suppresses CD4+CD44highCD62L- effector memory T cell-mediated colitis. Am. J. Physiol. Gastrointest. Liver Physiol.. 2006.08; 291 (2): G267-G274. ( PubMed, DOI )

50. Teruji Totsuka, Takanori Kanai, Shin Makita, Rei Fujii, Yasuhiro Nemoto, Shigeru Oshima, Ryuichi Okamoto, Akemi Koyanagi, Hisaya Akiba, Ko Okumura, Hideo Yagita, Mamoru Watanabe. Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells. Eur. J. Immunol.. 2005.06; 35 (6): 1773-1785. ( PubMed, DOI )

51. Tomoko Matsumoto, Ryuichi Okamoto, Tomoharu Yajima, Takehiko Mori, Shinichiro Okamoto, Yasuo Ikeda, Makio Mukai, Motomi Yamazaki, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Takanori Kanai, Hideyuki Okano, Johji Inazawa, Toshifumi Hibi, Mamoru Watanabe. Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine. Gastroenterology. 2005.06; 128 (7): 1851-1867. ( PubMed )

52. Shin Namiki, Tetsuya Nakamura, Shigeru Oshima, Motomi Yamazaki, Yuko Sekine, Kiichiro Tsuchiya, Ryuichi Okamoto, Takanori Kanai, Mamoru Watanabe. IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome. FEBS Lett.. 2005.05; 579 (13): 2781-2787. ( PubMed, DOI )

53. Eriko Okada, Motomi Yamazaki, Masanobu Tanabe, Tsutomu Takeuchi, Masanobu Nanno, Shigeru Oshima, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Takanori Kanai, Toshifumi Hibi, Mamoru Watanabe. IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice. Am. J. Physiol. Gastrointest. Liver Physiol.. 2005.04; 288 (4): G745-G754. ( PubMed, DOI )

54. Shin Makita, Takanori Kanai, Shigeru Oshima, Koji Uraushihara, Teruji Totsuka, Taisuke Sawada, Tetsuya Nakamura, Kazutaka Koganei, Tsuneo Fukushima, Mamoru Watanabe. CD4+CD25bright T cells in human intestinal lamina propria as regulatory cells. J. Immunol.. 2004.09; 173 (5): 3119-3130. ( PubMed )

55. Nobuhiko Kanazawa, Masayuki Kurosaki, Naoya Sakamoto, Nobuyuki Enomoto, Yasuhiro Itsui, Tsuyoshi Yamashiro, Yoko Tanabe, Shinya Maekawa, Mina Nakagawa, Cheng-Hsin Chen, Sei Kakinuma, Shigeru Oshima, Tetsuya Nakamura, Takanobu Kato, Takaji Wakita, Mamoru Watanabe. Regulation of hepatitis C virus replication by interferon regulatory factor 1. J. Virol.. 2004.09; 78 (18): 9713-9720. ( PubMed, DOI )

56. Oshima S, Nakamura T, Namiki S, Okada E, Tsuchiya K, Okamoto R, Yamazaki M, Yokota T, Aida M, Yamaguchi Y, Kanai T, Handa H, Watanabe M. Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. Mol Cell Biol. 2004.07; 24 (14): 6298-6310. ( PubMed, DOI )

57. Motomi Yamazaki, Tomoharu Yajima, Masanobu Tanabe, Kazuto Fukui, Eriko Okada, Ryuichi Okamoto, Shigeru Oshima, Tetsuya Nakamura, Takanori Kanai, Masahiro Uehira, Tsutomu Takeuchi, Hiromichi Ishikawa, Toshifumi Hibi, Mamoru Watanabe. Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis. J. Immunol.. 2003.08; 171 (3): 1556-1563. ( PubMed )

58. Takanori Kanai, Koji Uraushihara, Teruji Totsuka, Akira Okazawa, Toshifumi Hibi, Shigeru Oshima, Tatsuya Miyata, Tetsuya Nakamura, Mamoru Watanabe. Macrophage-derived IL-18 targeting for the treatment of Crohn's disease. Curr Drug Targets Inflamm Allergy. 2003.06; 2 (2): 131-136. ( PubMed )

59. Matsuda Hiroki, Nibe-Shirakihara Yoichi, Tamura Akiko, Aonuma Emi, Arakawa Satoko, Otsubo Kana, Nemoto Yasuhiro, Nagaishi Takashi, Tsuchiya Kiichiro, Shimizu Shigeomi, Ma Averil, Watanabe Mamoru, Uo Motohiro, Okamoto Ryuichi, Oshima Shigeru. Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2022.02; 592 74-80. ( PubMed, DOI )

60. 大島　茂. 重要な鍵分子の研究動向〜炎症性腸疾患（クローン病） 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術. 2021.08; 287-296.