論文・総説 - 大島　茂

21. Fumiaki Ishibashi, Hiromichi Shimizu, Toru Nakata, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Sho Anzai, Reiko Kuno, Sayaka Nagata, Go Ito, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, Ryuichi Okamoto. Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium. [Epub ahead of print] Stem Cell Reports. 2017.12; 10 (1): 27-42. ( PubMed, DOI )

22. Shuji Hibiya, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Nobukatsu Horita, Sho Watanabe, Tomoaki Shirasaki, Ryu Nishimura, Natsuko Kimura, Tatsunori Nishimura, Noriko Gotoh, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Long-term Inflammation Transforms Intestinal Epithelial Cells of Colonic Organoids. J Crohns Colitis. 2017.05; 11 (5): 621-630. ( PubMed, DOI )

23. Chiaki Maeyashiki, Shigeru Oshima, Kana Otsubo, Masanori Kobayashi, Yoichi Nibe, Yu Matsuzawa, Michio Onizawa, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. HADHA, the alpha subunit of the mitochondrial trifunctional protein, is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells. Biochem. Biophys. Res. Commun.. 2017.03; 484 (3): 636-641. ( PubMed, DOI )

24. Toru Nakata, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Reiko Kuno, Sho Anzai, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe, Ryuichi Okamoto. Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine. Data Brief. 2017.02; 10 551-556. ( PubMed, DOI )

25. Toru Nakata, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Reiko Kuno, Sho Anzai, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe, Ryuichi Okamoto. Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors. Biochem. Biophys. Res. Commun.. 2017.01; 482 (4): 1296-1303. ( PubMed, DOI )

26. Akiyama Shintaro, Mochizuki Wakana, Nibe Yoichi, Matsumoto Yuka, Sakamoto Kei, Oshima Shigeru, Watanabe Mamoru, Nakamura Tetsuya. CCN3 Expression Marks a Sulfomucin-nonproducing Unique Subset of Colonic Goblet Cells in Mice ACTA HISTOCHEMICA ET CYTOCHEMICA. 2017; 50 (6): 159-168. ( PubMed, DOI )

27. Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Tatsuro Murano, Go Ito, Hiromichi Shimizu, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Akihiro Araki, Kazuo Ohtsuka, Ryuichi Okamoto, Mamoru Watanabe. PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells. Sci Rep. 2016.11; 6 36795. ( PubMed, DOI )

28. Masanori Kobayashi, Shigeru Oshima, Chiaki Maeyashiki, Yoichi Nibe, Kana Otsubo, Yu Matsuzawa, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development. Sci Rep. 2016.11; 6 36780. ( PubMed, DOI )

29. Taichi Matsumoto, Wakana Mochizuki, Yoichi Nibe, Shintaro Akiyama, Yuka Matsumoto, Kengo Nozaki, Masayoshi Fukuda, Ayumi Hayashi, Tomohiro Mizutani, Shigeru Oshima, Mamoru Watanabe, Tetsuya Nakamura. Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism. PLoS ONE. 2016.08; 11 (8): e0162049. ( PubMed, DOI )

30. Klionsky DJ, Oshima S, et al. （2387 人中1536 番目）. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016.01; 12 (1): 1-222. ( PubMed, DOI )

31. Michio Onizawa, Shigeru Oshima, Ulf Schulze-Topphoff, Juan A Oses-Prieto, Timothy Lu, Rita Tavares, Thomas Prodhomme, Bao Duong, Michael I Whang, Rommel Advincula, Alex Agelidis, Julio Barrera, Hao Wu, Alma Burlingame, Barbara A Malynn, Scott S Zamvil, Averil Ma. The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis Nat Immunol. 2015.06; 16 (6): 618-627. ( PubMed, DOI )

32. Yu Matsuzawa, Shigeru Oshima, Masahiro Takahara, Chiaki Maeyashiki, Yasuhiro Nemoto, Masanori Kobayashi, Yoichi Nibe, Kengo Nozaki, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Averil Ma, Mamoru Watanabe. TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy. Autophagy. 2015.06; 11 (7): 1052-1062. ( PubMed, DOI )

33. Keita Fukushima, Kiichiro Tsuchiya, Yoshihito Kano, Nobukatsu Horita, Shuji Hibiya, Ryohei Hayashi, Keisuke Kitagaki, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Shigeru Oshima, Takashi Nagaishi, Okamoto Ryuichi, Tetsuya Nakamura, Mamoru Watanabe. Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line. Cancer Sci.. 2015.05; ( PubMed, DOI )

34. Yu Matsuzawa, Shigeru Oshima, Yoichi Nibe, Masanori Kobayashi, Chiaki Maeyashiki, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62. Biochem. Biophys. Res. Commun.. 2015.01; 456 (1): 298-304. ( PubMed, DOI )

35. Masahiro Suzuki, Takashi Nagaishi, Motomi Yamazaki, Michio Onizawa, Taro Watabe, Yuriko Sakamaki, Shizuko Ichinose, Mamoru Totsuka, Shigeru Oshima, Ryuichi Okamoto, Motoyuki Shimonaka, Hideo Yagita, Tetsuya Nakamura, Mamoru Watanabe. Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis. PLoS ONE. 2014.02; 9 (2): e88369. ( PubMed, DOI )

36. Masahiro Takahara, Yasuhiro Nemoto, Shigeru Oshima, Yu Matsuzawa, Takanori Kanai, Ryuichi Okamoto, Kiichiro Tsuchiyaa, Tetsuy Nakamura, Kazuhide Yamamoto, Mamoru Watanabe.. IL-7 promotes long-term in vitro survival of unique long-lived memory subset generated from mucosal effector memory CD4+ T cells in chronic colitis mice. Immunol Lett. 2013.11; 156 (1-2): 82-93. ( PubMed, DOI )

37. Yasuhiro Nemoto, Takanori Kanai, Masahiro Takahara, Shigeru Oshima, Tetsuya Nakamura, Ryuichi Okamoto, Kiichiro Tsuchiya, and Mamoru Watanabe.. Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4 memory T cells. Gut. 2013.08; 62 (8): 1142-1152. ( PubMed, DOI )

38. Callahan JA, Hammer GE, Agelides A, Duong BH, Oshima S, North J, Advincula R, Shifrin N, Truong HA, Paw J, Barrera J, DeFranco A, Rosenblum MD, Malynn BA, Ma A. ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells. J Immunol. 2013.07; 191 (2): 535-539. ( PubMed, DOI )

39. Yasuhiro Nemoto, Takanori Kanai, Masahiro Takahara, Shigeru Oshima, Ryuichi Okamoto, Kiichiro Tsuchiya, Satoshi Matsumoto and Mamoru Watanabe.. Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota. J Immunol. 2013.06; 190 (12): 6616-6625. ( PubMed, DOI )

40. Shao L, Oshima S, Duong B, Advincula R, Barrera J, Malynn BA, Ma A. A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PLoS ONE. 2013.05; 8 (5): e62223. ( PubMed, DOI )