論文・総説 - 淺原　弘嗣

81. Ogura Y, Miyake N, Kou I, Iida A, Nakajima M, Takeda K, Fujibayashi S, Shiina M, Okada E, Toyama Y, Iwanami A, Ishii K, Ogata K, Asahara H, Matsumoto N, Nakamura M, Matsumoto M, Ikegawa S. Identification of HOXD4 Mutations in Spinal Extradural Arachnoid Cyst PLoS One. 2015.11; ( PubMed, DOI )

82. Ryosuke Tateishi , Nobuko Akiyama , Maki Miyauchi, Riko Yoshinaga, Hiroki Sasanuma, Takashi Kudo, Miki Shimbo, Masahiro Shinohara, Koji Obata, Jun-ichiro Inoue, Masaki Shirakawa, Dai Shiba, Hiroshi Asahara, Nobuaki Yoshida, Satoru Takahashi, Hironobu Morita , Taishin Akiyama. Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice. PLoS One. 2015.10; 10 ( PubMed, DOI )

83. Gernapudi R, Wolfson B, Zhang Y, Yao Y, Yang P, Asahara H, Zhou Q. MicroRNA 140 Promotes Expression of Long Noncoding RNA NEAT1 in Adipogenesis Mol Cell Biol. 2015.10; ( PubMed, DOI )

84. Matsubara Y, Kato T, Kashimada K, Tanaka H, Zhi Z, Ichinose S, Mizutani S, Morio T, Chiba T, Ito Y, Saga Y, Takada S, Asahara H. TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis. Stem Cells Dev. 2015.05; 1164-1170. ( PubMed, DOI )

85. Otabe Koji, Nakahara Hiroyuki, Hasegawa Akihiko, Matsukawa Tetsuya, Ayabe Fumiaki, Onizuka Naoko, Inui Masafumi, Takada Shuji, Ito Yoshiaki, Sekiya Ichiro, Muneta Takeshi, Lotz Martin, Asahara Hiroshi. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. J Orthop Res. 2015.01; 33 (1): 1-8. ( PubMed, DOI )

86. Nagata Eiko, Kano Hiroki, Kato Fumiko, Yamaguchi Rie, Nakashima Shinichi, Takayama Shinichiro, Kosaki Rika, Tonoki Hidefumi, Mizuno Seiji, Watanabe Satoshi, Yoshiura Koh-Ichiro, Kosho Tomoki, Hasegawa Tomonobu, Kimizuka Mamori, Suzuki Atsushi, Shimizu Kenji, Ohashi Hirofumi, Haga Nobuhiko, Numabe Hironao, Horii Emiko, Nagai Toshiro, Yoshihashi Hiroshi, Nishimura Gen, Toda Tatsushi, Takada Shuji, Yokoyama Shigetoshi, Asahara Hiroshi, Sano Shinichiro, Fukami Maki, Ikegawa Shiro, Ogata Tsutomu. Japanese founder duplications/triplications involving BHLHA9 are associated with split-hand/foot malformation with or without long bone deficiency and Gollop-Wolfgang complex. Orphanet J Rare Dis. 2014.10; 9 (1): 125. ( PubMed, DOI )

87. Miyata Kohei, Yotsumoto Fusanori, Nam Sung Ouk, Odawara Takashi, Manabe Sadao, Ishikawa Toyokazu, Itamochi Hiroaki, Kigawa Junzo, Takada Shuji, Asahara Hiroshi, Kuroki Masahide, Miyamoto Shingo. Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma. Cancer Med. 2014.10; 3 (5): 1159-1169. ( PubMed, DOI )

88. Miyata Kohei, Miyata Tomoko, Nakabayashi Kazuhiko, Okamura Kohji, Naito Masashi, Kawai Tomoko, Takada Shuji, Kato Kiyoko, Miyamoto Shingo, Hata Kenichiro, Asahara Hiroshi. DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation. Hum Mol Genet. 2014.09; 24 (2): 410-423. ( PubMed, DOI )

89. Takasawa Kei, Kashimada Kenichi, Pelosi Emanuele, Takagi Masatoshi, Morio Tomohiro, Asahara Hiroshi, Schlessinger David, Mizutani Shuki, Koopman Peter. FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J. 2014.05; 28 (5): 2020-2028. ( PubMed, DOI )

90. Shinohara Masahiro, Chang Betty Y, Buggy Joseph J, Nagai Yusuke, Kodama Tatsuhiko, Asahara Hiroshi, Takayanagi Hiroshi. The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss. Bone. 2014.03; 60 8-15. ( PubMed, DOI )

91. Onizuka Naoko, Ito Yoshiaki, Inagawa Masayo, Nakahara Hiroyuki, Takada Shuji, Lotz Martin, Toyama Yoshiaki, Asahara Hiroshi. The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates. J Orthop Sci. 2014.01; 19 (1): 172-180. ( PubMed, DOI )

92. Akasaki Y, Hasegawa A, Saito M, Asahara H, Iwamoto Y, Lotz M K. Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis. Osteoarthritis Cartilage. 2014.01; 22 (1): 162-170. ( PubMed, DOI )

93. Matsubara Yohei, Chiba Tomoki, Kashimada Kenichi, Morio Tomohiro, Takada Shuji, Mizutani Shuki, Asahara Hiroshi. Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus. Sci Rep. 2014; 4 5043. ( PubMed, DOI )

94. Inui Masafumi, Miyado Mami, Igarashi Maki, Tamano Moe, Kubo Atsushi, Yamashita Satoshi, Asahara Hiroshi, Fukami Maki, Takada Shuji. Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system. Sci Rep. 2014; 4 5396. ( PubMed, DOI )

95. Yoshitaka Teruhito, Kawai Akira, Miyaki Shigeru, Numoto Kunihiko, Kikuta Kazutaka, Ozaki Toshifumi, Lotz Martin, Asahara Hiroshi. Analysis of microRNAs expressions in chondrosarcoma. J Orthop Res. 2013.12; 31 (12): 1992-1998. ( PubMed, DOI )

96. Kato Tomoko, Miyata Kohei, Sonobe Miku, Yamashita Satoshi, Tamano Moe, Miura Kento, Kanai Yoshiakira, Miyamoto Shingo, Sakuma Tetsushi, Yamamoto Takashi, Inui Masafumi, Kikusui Takefumi, Asahara Hiroshi, Takada Shuji. Production of Sry knockout mouse using TALEN via oocyte injection. Sci Rep. 2013.11; 3 3136. ( PubMed, DOI )

97. Shimizu Hirohito, Kubo Atsushi, Uchibe Kenta, Hashimoto Megumi, Yokoyama Shigetoshi, Takada Shuji, Mitsuoka Kazuhiko, Asahara Hiroshi. The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013.10; 8 (10): e75754. ( PubMed, DOI )

98. Takada Shuji, Sato Tempei, Ito Yoshiaki, Yamashita Satoshi, Kato Tomoko, Kawasumi Miyuri, Kanai-Azuma Masami, Igarashi Arisa, Kato Tomomi, Tamano Moe, Asahara Hiroshi. Targeted gene deletion of miRNAs in mice by TALEN system. PLoS One. 2013.10; 8 (10): e76004. ( PubMed, DOI )

99. Gibson Gary, Asahara Hiroshi. microRNAs and cartilage. J Orthop Res. 2013.09; 31 (9): 1333-1344. ( PubMed, DOI )

100. Nakahara Hiroyuki, Hasegawa Akihiko, Otabe Koji, Ayabe Fumiaki, Matsukawa Tetsuya, Onizuka Naoko, Ito Yoshiaki, Ozaki Toshifumi, Lotz Martin K, Asahara Hiroshi. Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation. Arthritis Rheum. 2013.08; 65 (8): 2081-2089. ( PubMed, DOI )