論文・総説 - 淺原　弘嗣

21. Kaho Takada, Tomoki Chiba, Takayuki Miyazaki, Lisa Yagasaki, Ryo Nakamichi, Takanori Iwata, Keiji Moriyama, Hiroyuki Harada, Hiroshi Asahara. Single Cell RNA Sequencing Reveals Critical Functions of Mkx in Periodontal Ligament Homeostasis Front Cell Dev Biol. 2022.02; 10 795441. ( PubMed, DOI )

22. Hiroki Tsutsumi, Ryota Kurimoto, Ryo Nakamichi, Tomoki Chiba, Takahide Matsushima, Yuta Fujii, Risa Sanada, Tomomi Kato, Kana Shishido, Yuriko Sakamaki, Tsuyoshi Kimura, Akio Kishida, Hiroshi Asahara. Generation of a tendon-like tissue from human iPS cells. J Tissue Eng. 2022.01; 13 20417314221074018. ( PubMed, DOI )

23. Yoshiaki Ito, Tokio Matsuzaki, Fumiaki Ayabe, Sho Mokuda, Ryota Kurimoto, Takahide Matsushima, Yusuke Tabata, Maiko Inotsume, Hiroki Tsutsumi, Lin Liu, Masahiro Shinohara, Yoko Tanaka, Ryo Nakamichi, Keiichiro Nishida, Martin K Lotz, Hiroshi Asahara. Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis. Nat Commun. 2021.07; 12 (1): 4148. ( PubMed, DOI )

24. Takayuki Miyazaki, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Ryo Nakamichi, Hiroki Tsutsumi, Kaho Takada, Lisa Yagasaki, Tomomi Kato, Kana Shishido, Yukiho Kobayashi, Tsutomu Matsumoto, Keiji Moriyama, Hiroshi Asahara. Mkx regulates the orthodontic tooth movement via osteoclast induction. J Bone Miner Metab. 2021.05; 39 (5): 780-786. ( PubMed, DOI )

25. Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Tomoki Chiba, Yuki Inutani, Hiroshi Asahara. Identification of chemical compounds regulating PD-L1 by introducing HiBiT-tagged cells. FEBS Lett. 2021.03; 595 (5): 563-576. ( PubMed, DOI )

26. Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, Yoshiaki Ito, Ryo Nakamichi, Martin Lotz, Hiroshi Asahara. MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes. Methods Mol Biol. 2021; 2245 151-166. ( PubMed, DOI )

27. Keiko Itano,KojiOchiai, Takahide Matsushima,Hiroshi Asahara and Koichi Takahashi. Automation of Foci-Cell-State Judgement with Regression Models Transactions of the Institute of Systems, Control and Information Engineers. 2021; 34 (3): 69-80. ( DOI )

28. Ryota Kurimoto, Tomoki Chiba, Yoshiaki Ito, Takahide Matsushima, Yuki Yano, Kohei Miyata, Yuka Yashiro, Tsutomu Suzuki, Kozo Tomita, Hiroshi Asahara. The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. EMBO J. 2020.10; 39 (20): e104708. ( PubMed, DOI )

29. Kwang Il Lee, Ramya Gamini, Merissa Olmer, Yasunari Ikuta, Joe Hasei, Jihye Baek, Oscar Alvarez-Garcia, Shawn P Grogan, Darryl D D'Lima, Hiroshi Asahara, Andrew I Su, Martin K Lotz. Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity. Sci Transl Med. 2020.10; 12 (567): 7967. ( PubMed, DOI )

30. Ryo Nakamichi, Ryota Kurimoto, Yusuke Tabata, Hirosi Asahara. Transcriptional, epigenetic and microRNA regulation of growth plate. Bone. 2020.08; 137 115434. ( PubMed, DOI )

31. Ryo Nakamichi, Hiroshi Asahara. Regulation of tendon and ligament differentiation. Bone. 2020.08; 115609. ( PubMed, DOI )

32. Mokuda S, Nakamichi R, Ito Y, Asahara H. Genetic, Epigenetic, and MicroRNA Regulation of Osteoarthritis Encyclopedia of Bone Biology, vol.[1]. 2020.06; 1 641-651.

33. Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara. Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates Elife. 2020.05; 9 ( PubMed, DOI )

34. Ryo Nakamichi, Hiroshi Asahara. The transcription factors regulating intervertebral disc development. JOR Spine. 2020.03; 3 (1): e1081. ( PubMed, DOI )

35. Eric Gracey, Arne Burssens, Isabelle Cambré, Georg Schett, Rik Lories, Iain B McInnes, Hiroshi Asahara, Dirk Elewaut. Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis. Nat Rev Rheumatol. 2020.02; 16 (4): 193-207. ( PubMed, DOI )

36. Kensuke Kataoka, Ryota Kurimoto, Hiroki Tsutsumi, Tomoki Chiba, Tomomi Kato, Kana Shishido, Mariko Kato, Yoshiaki Ito, Yuichiro Cho, Osamu Hoshi, Ayako Mimata, Yuriko Sakamaki, Ryo Nakamichi, Martin K Lotz, Keiji Naruse, Hiroshi Asahara. In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System Front Cell Dev Biol. 2020; 8 307. ( PubMed, DOI )

37. Yuki Yano, Tomoki Chiba, Hiroshi Asahara. Analysis of the Mouse Y Chromosome by Single-Molecule Sequencing With Y Chromosome Enrichment. Front Genet. 2020; 11 406. ( PubMed, DOI )

38. Hiroto Yamamoto, Yutaro Uchida, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, Maiko Inotsume, Chihiro Ishikawa, Haiyan Li, Takashi Shiga, Masafumi Muratani, Tokujiro Uchida, Hiroshi Asahara. Transcriptome analysis of sevoflurane exposure effects at the different brain regions. PLoS One. 2020; 15 (12): e0236771. ( PubMed, DOI )

39. Carmen Adriaens, Florian Rambow, Greet Bervoets, Toomas Silla, Mari Mito, Tomoki Chiba, Hiroshi Asahara, Tetsuro Hirose, Shinichi Nakagawa, Torben Heick Jensen, Jean-Christophe Marine. The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth. RNA. 2019.12; 25 (12): 1681-1695. ( PubMed, DOI )

40. Momo Isobe, Hikaru Toya, Mari Mito, Tomoki Chiba, Hiroshi Asahara, Tetsuro Hirose, Shinichi Nakagawa. Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice. RNA. 2019.12; ( PubMed, DOI )