Published Papers & Misc - OKAZAWA Hitoshi

Division display  81 - 100 of about 118 ／  All the affair displays >>

  1. Inagaki R, Tagawa K, Qi ML, Enokido Y, Ito H, Tamura T, Shimizu S, Oyanagi K, Arai N, Kanazawa I, Wanker EE, Okazawa H. Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington's disease. Eur. J. Neurosci. 2008.07; 28 (1): 30-40. ( PubMed, DOI )

  2. Qi ML, Tagawa K, Enokido Y, Yoshimura N, Wada Y, Watase K, Ishiura S, Kanazawa I, Botas J, Saitoe M, Wanker EE, Okazawa H. Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases. Nat Cell Biol. 2007.04; 9 (4): 402-414. ( PubMed, DOI )

  3. Tagawa K, Marubuchi S, Qi ML, Enokido Y, Tamura T, Inagaki R, Murata M, Kanazawa I, Wanker EE, Okazawa H. The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes. J Neurosci. 2007.01; 27 (4): 868-880. ( PubMed, DOI )

  4. Marubuchi S, Okuda T, Tagawa K, Enokido Y, Horiuchi D, Shimokawa R, Tamura T, Qi ML, Eishi Y, Watabe K, Shibata M, Nakagawa M, Okazawa H. Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration J. Neurochem. 2006.10; 99 (1): 70-83. ( PubMed, DOI )

  5. Yoshimura N, Horiuchi D, Shibata M, Saitoe M, Qi ML, Okazawa H. Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship. FEBS Lett. 2006.04; 580 (9): 2335-2340. ( PubMed, DOI )

  6. Hoshino M, Qi ML, Yoshimura N, Miyashita T, Tagawa K, Wada Y, Enokido Y, Marubuchi S, Harjes P, Arai N, Oyanagi K, Blandino G, Sudol M, Rich T, Kanazawa I, Wanker EE, Saitoe M, Okazawa H. Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73. J Cell Biol. 2006.02; 172 (4): 589-604. ( PubMed, DOI )

  7. Enokido Y, Suzuki E, Iwasawa K, Namekata K, Okazawa H, Kimura H. Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS FASEB J. 2005.11; 19 (13): 1854-1856. ( PubMed, DOI )

  8. Marubuchi S, Wada Y, Okuda T, Hara Y, Qi ML, Hoshino M, Nakagawa M, Kanazawa I, Okazawa H. PQBP -1 dysfunction induces cell death of neurons through mitochondrial stress. J Neurochem. 2005.11; 95 (3): 858-870. ( PubMed, DOI )

  9. Qi Y, Hoshino M, Wada Y, Marubuchi S, Yoshimura N, Kanazawa I, Shinomiya K, Okazawa H. PQBP-1 is expressed predominantly in the central nervous system during development. Eur J Neurosci. 2005.09; 22 (6): 1277-1286. ( PubMed, DOI )

  10. Okuda T, Tagawa K, Qi ML, Hoshio M, Ueda H, Kawano H, Kanazawa I, Muramatsu M, Okazawa H. Oct-3/4 repression accelerates differentiation of neural progenitor cells in vitro and in vivo. Brain Res Mol Brain Res. 2004.12; 132 (1): 18-30. ( PubMed, DOI )

  11. Tagawa K, Hoshino M, Okuda T, Ueda H, Hayashi H, Engemann S, Okado H, Ichikawa M, Wanker EE, Okazawa H. Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein. J Neurochem. 2004.05; 89 (4): 974-987. ( PubMed, DOI )

  12. Hoshino M, Tagawa K, Okuda T, Ueda H, Okazawa H . General transcriptional repression by polyglutamine disease proteins is not directly linked to the presence of inclusion bodies Biochem. Biophys. Res. Commun. 2004.01; 313 (1): 110-116. ( PubMed, DOI )

  13. Hoshino M, Tagawa K, Okuda T, Murata M, Oyanagi K, Arai N, Mizutani T, Kanazawa I, Wanker EE, Okazawa H . Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein J. Neurochem. 2003.10; 87 (１): 257-267. ( PubMed, DOI )

  14. Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE. Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease. J Biol Chem. 2003.10; 278 (42): 41452-41461. ( PubMed, DOI )

  15. Okuda T, Hattori H, Takeuchi S, Shimizu J, Ueda H, Palvimo JJ, Kanazawa I, Kawano H, Nakagawa M, Okazawa H. PQBP-1 transgenic mice show a late-onset motor neuron disease-like phenotype. Hum Mol Genet. 2003.04; 12 (7): 711-725. ( PubMed, DOI )

  16. Enokido Y, Maruoka H, Hatanaka H, Kanazawa I, Okazawa H. PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neurons Biochem. Biophys. Res. Commun. 2002.06; 294 (2): 268-271. ( PubMed, DOI )

  17. Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I. Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death. Neuron. 2002.05; 34 (5): 701-713. ( PubMed, DOI )

  18. Ueda H, Goto J, Hashida H, Lin X, Oyanagi K, Kawano H, Zoghbi HY, Kanazawa I, Okazawa H. Enhanced SUMOylation in polyglutamine diseases. Biochem Biophys Res Commun. 2002.04; 293 (1): 307-313. ( PubMed, DOI )

  19. Okazawa H, Sudol M, Rich T. PQBP-1 (Np/PQ): a polyglutamine tract-binding and nuclear inclusion-forming protein. Brain Res Bull. 2001.11; 56 (3-4): 273-280. ( PubMed, DOI )

  20. Shoji M, Iwakami N, Takeuchi S, Waragai M, Suzuki M, Kanazawa I, Lippa CF, Ono S, Okazawa H. JNK activation is associated with intracellular beta-amyloid accumulation. Brain Res Mol Brain Res. 2000.12; 85 (1-2): 221-233. ( PubMed, DOI )

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