Published Papers & Misc - OKAZAWA Hitoshi

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  1. Tamura T, Sone M, Nakamura Y, Shimamura T, Imoto S, Miyano S, Okazawa H. A restricted level of PQBP1 is needed for the best longevity of Drosophila. Neurobiol Aging. 2013.01; 34 (1): 356.e11-356.e20. ( PubMed, DOI )

  2. Martin Rees, Christian Gorba, Cesira de Chiara, Tam T T Bui, Mitla Garcia-Maya, Alex F Drake, Hitoshi Okazawa, Annalisa Pastore, Dmitri Svergun, Yu Wai Chen. Solution model of the intrinsically disordered polyglutamine tract-binding protein-1. Biophys J. 2012.04; 102 (7): 1608-1616. ( PubMed, DOI )

  3. Nakamura Y, Tagawa K, Oka T, Sasabe T, Ito H, Shiwaku H, La Spada AR, Okazawa H. Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network. Hum Mol Genet. 2012.03; 21 (5): 1099-1110. ( PubMed, DOI )

  4. Tamura T, Sone M, Iwatsubo T, Tagawa K, Wanker EE, Okazawa H. Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease. PLoS ONE. 2011.11; 6 (11): e27408. ( PubMed, DOI )

  5. Oka T, Tagawa K, Ito H, Okazawa H. Dynamic changes of the phosphoproteome in postmortem mouse brains. PLoS ONE. 2011.06; 6 (6): e21405. ( PubMed, DOI )

  6. Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda SI. In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse. Mol Ther. 2010.11; 18 (11): 1995-2005. ( PubMed, DOI )

  7. Konno M, Hamazaki TS, Fukuda S, Tokuhara M, Uchiyama H, Okazawa H, Okochi H, Asashima M. Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture. Biochem Biophys Res Commun. 2010.10; 400 (4): 461-465. ( PubMed, DOI )

  8. Tamura T, Horiuchi D, Chen YC, Sone M, Miyashita T, Saitoe M, Yoshimura N, Chiang AS, Okazawa H. Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning. J. Neurosci. 2010.10; 30 (42): 14091-14101. ( PubMed, DOI )

  9. Honda S, Hayashi S, Imoto I, Toyama J, Okazawa H, Nakagawa E, Goto Y, Inazawa J. Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis. J. Hum. Genet. 2010.09; 55 (9): 590-599. ( PubMed, DOI )

  10. Takahashi M, Mizuguchi M, Shinoda H, Aizawa T, Demura M, Okazawa H, Kawano K. Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain. Biochim Biophys Acta. 2010.07; 1804 (7): 1500-1507. ( PubMed, DOI )

  11. Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, Watase K, Tagawa K, Okazawa H. Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J. 2010.07; 29 (14): 2446-2460. ( PubMed, DOI )

  12. Enokido Y, Tamura T, Ito H, Arumughan A, Komuro A, Shiwaku H, Sone M, Foulle R, Sawada H, Ishiguro H, Ono T, Murata M, Kanazawa I, Tomilin N, Tagawa K, Wanker EE, Okazawa H. Mutant huntingtin impairs Ku70-mediated DNA repair. J Cell Biol. 2010.05; 189 (3): 425-443. ( PubMed, DOI )

  13. Ito H, Yoshimura N, Kurosawa M, Ishii S, Nukina N, Okazawa H. Knock-down of PQBP1 impairs anxiety-related cognition in mouse. Hum Mol Genet. 2009.11; 18 (22): 4239-4254. ( PubMed, DOI )

  14. Chin JH, Shiwaku H, Goda O, Komuro A, Okazawa H. Neural stem cells express Oct-3/4. Biochem Biophys Res Commun. 2009.10; 388 (2): 247-251. ( PubMed, DOI )

  15. Takahashi M, Mizuguchi M, Shinoda H, Tomoyasu AT, Demura M, Okazawa H, Kawano K. Polyglutamine tract binding protein-1 is an intrinsically unstructured protein Biochim. Biophys. Acta. 2009.06; 1794 (6): 936-943. ( PubMed, DOI )

  16. Morimoto N, Nagai M, Miyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T, Okazawa H, Abe K. Progressive decrease in the level of YAPdeltaCs, pro-survival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene J Neurosci Res. 2009.03; 87 (4): 928-936. ( PubMed )

  17. Sone M, Uchida A, Komatsu A, Suzuki E, Ibuki I, Asada M, Shiwaku H, Tamura T, Hoshino M, Okazawa H, Nabeshima Y. Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening. PLoS ONE. 2009.02; 4 (2): e4466. ( PubMed, DOI )

  18. Tamura T, Sone M, Yamashita M, Wanker EE, Okazawa H. Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models. PLoS ONE. 2009.01; 4 (1): e4262. ( PubMed, DOI )

  19. Takahashi K, Yoshina S, Maekawa M, Ito W, Inoue T, Shiwaku H, Arai H, Mitani S, Okazawa H. Nematode Homologue of PQBP1, a Mental Retardation Causative Gene, Is Involved in Lipid Metabolism PLoS One. 2009; 4 (1): e4104. ( PubMed, DOI )

  20. Enokido Y, Yoshitake A, Ito H, Okazawa H. Age-dependent change of HMGB1 and DNA double-strand break accumulation in mouse brain Biochem Biophys Res Commun. 2008.11; 376 (1): 128-133. ( PubMed, DOI )

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