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Okawa Y, Sasagawa S, Kato H, Johnson TA, Nagaoka K, Kobayashi Y, Hayashi A, Shibayama T, Maejima K, Tanaka H, Miyano S, Shibahara J, Nishizuka S, Hirano S, Seto Y, Iwaya T, Kakimi K, Yasuda T, Nakagawa H: Immuno-genomic analysis reveals eosinophilic feature and favorable prognosis of female non-smoking esophageal squamous cell carcinomas. Cancer letters. 2024.01; 581 216499. ( PubMed , DOI )

Kawachi K, Tang X, Kasajima R, Yamanaka T, Shimizu E, Katayama K, Yamaguchi R, Yokoyama K, Yamaguchi K, Furukawa Y, Miyano S, Imoto S, Yoshioka E, Washimi K, Okubo Y, Sato S, Yokose T, Miyagi Y: Genetic analysis of low-grade adenosquamous carcinoma of the breast progressing to high-grade metaplastic carcinoma. Breast cancer research and treatment. 2023.12; 202 (3): 563-573. ( PubMed , DOI )

Wang QS, Edahiro R, Namkoong H, Hasegawa T, Shirai Y, Sonehara K, Japan COVID-19 Task Force, Kumanogoh A, Ishii M, Koike R, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Okada Y: Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision. NAR genomics and bioinformatics. 2023.12; 5 (4): lqad090. ( PubMed , DOI )

Kusumoto T, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Nakagawara K, Fukushima T, Morita A, Watase M, Asakura T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Murakami K, Sato Y, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K: Characteristics of patients with COVID-19 who have deteriorating chest X-ray findings within 48 h: a retrospective cohort study. Scientific reports. 2023.12; 13 (1): 22054. ( PubMed , DOI )

Masatoshi Takagi, Akihiro Hoshino, Kristine Bousset, Jule Röddecke, Hanna Luisa Martin, Iulia Folcut, Dan Tomomasa, Xi Yang, Junya Kobayashi, Naoki Sakata, Kenichi Yoshida, Satoru Miyano, Seishi Ogawa, Seiji Kojima, Tomohiro Morio, Thilo Dörk, Hirokazu Kanegane: Bone Marrow Failure and Immunodeficiency Associated with Human RAD50 Variants. J Clin Immunol. 2023.11; 43 (8): 2136-2145. ( PubMed , DOI )

Sakurai K, Chubachi S, Asakura T, Namkoong H, Tanaka H, Azekawa S, Shimada T, Otake S, Nakagawara K, Fukushima T, Lee H, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K: Prognostic significance of hypertension history and blood pressure on admission in Japanese patients with coronavirus disease 2019: integrative analysis from the Japan COVID-19 Task Force. Hypertension research : official journal of the Japanese Society of Hypertension. 2023.11; ( PubMed , DOI )

Tanaka H, Maetani T, Chubachi S, Tanabe N, Shiraishi Y, Asakura T, Namkoong H, Shimada T, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Hasegawa N, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K: Clinical utilization of artificial intelligence-based COVID-19 pneumonia quantification using chest computed tomography - a multicenter retrospective cohort study in Japan. Respiratory research. 2023.10; 24 (1): 241. ( PubMed , DOI )

Nishimura T, Kakiuchi N, Yoshida K, Sakurai T, Kataoka TR, Kondoh E, Chigusa Y, Kawai M, Sawada M, Inoue T, Takeuchi Y, Maeda H, Baba S, Shiozawa Y, Saiki R, Nakagawa MM, Nannya Y, Ochi Y, Hirano T, Nakagawa T, Inagaki-Kawata Y, Aoki K, Hirata M, Nanki K, Matano M, Saito M, Suzuki E, Takada M, Kawashima M, Kawaguchi K, Chiba K, Shiraishi Y, Takita J, Miyano S, Mandai M, Sato T, Takeuchi K, Haga H, Toi M, Ogawa S: Evolutionary histories of breast cancer and related clones. Nature. 2023.08; 620 (7974): 607-614. ( PubMed , DOI )

Suzuki M, Kasajima R, Yokose T, Shimizu E, Hatakeyama S, Yamaguchi K, Yokoyama K, Katayama K, Yamaguchi R, Furukawa Y, Miyano S, Imoto S, Shinozaki-Ushiku A, Ushiku T, Miyagi Y: KMT2C expression and DNA homologous recombination repair factors in lung cancers with a high-grade fetal adenocarcinoma component. Translational lung cancer research. 2023.08; 12 (8): 1738-1751. ( PubMed , DOI )

Kobayashi Y, Niida A, Nagayama S, Saeki K, Haeno H, Takahashi KK, Hayashi S, Ozato Y, Saito H, Hasegawa T, Nakamura H, Tobo T, Kitagawa A, Sato K, Shimizu D, Hirata H, Hisamatsu Y, Toshima T, Yonemura Y, Masuda T, Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K: Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers. British journal of cancer. 2023.08; 129 (7): 1105-1118. ( PubMed , DOI )

Tanaka H, Chubachi S, Asakura T, Namkoong H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Lee H, Watase M, Sakurai K, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K: Characteristics and clinical effectiveness of COVID-19 vaccination in hospitalized patients in Omicron-dominated epidemic wave - a nationwide study in Japan. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2023.07; 132 84-88. ( PubMed , DOI )

Hara Y, Shiba N, Yoshida K, Yamato G, Kaburagi T, Shiraishi Y, Ohki K, Shiozawa Y, Kawamura M, Kawasaki H, Sotomatsu M, Takizawa T, Matsuo H, Shimada A, Kiyokawa N, Tomizawa D, Taga T, Ito E, Horibe K, Miyano S, Adachi S, Taki T, Ogawa S, Hayashi Y: TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid leukemia. Genes, chromosomes & cancer. 2023.07; 62 (7): 412-422. ( PubMed , DOI )

Tanaka H, Chubachi S, Namkoong H, Sato Y, Asakura T, Lee H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Sakurai K, Kusumoto T, Kondo Y, Masaki K, Kamata H, Ishii M, Kaneko Y, Hasegawa N, Ueda S, Sasaki M, Izumo T, Inomata M, Miyazawa N, Kimura Y, Suzuki Y, Harada N, Ichikawa M, Takata T, Ishikura H, Yoshiyama T, Kokuto H, Murakami K, Sano H, Ueda T, Kuwahara N, Fujiwara A, Ogura T, Inoue T, Asami T, Mutoh Y, Nakachi I, Baba R, Nishi K, Tani M, Kagyo J, Hashiguchi M, Oguma T, Asano K, Nishikawa M, Watanabe H, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K: Propensity-Score Matched Analysis of the Effectiveness of Baricitinib in Patients With Coronavirus Disease 2019 (COVID-19) Using Nationwide Real-World Data: An Observational Matched Cohort Study From the Japan COVID-19 Task Force. Open forum infectious diseases. 2023.07; 10 (7): ofad311. ( PubMed , DOI )

Ozawa T, Asakura T, Chubachi S, Namkoong H, Tanaka H, Lee K, Fukushima T, Otake S, Nakagawara K, Watase M, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force: Use of the neutrophil-to-lymphocyte ratio and an oxygen requirement to predict disease severity in patients with COVID-19. Respiratory investigation. 2023.07; 61 (4): 454-459. ( PubMed , DOI )

Latorre AAE, Nakamura K, Seino K, Hasegawa T.: Vector autoregression for forecasting the number of COVID-19 cases and analyzing behavioral indicators in the Philippines: an ecologic time-trend study, JMIR Form Res . 2023.06; 7 e46357. ( DOI )

Toshiki Sera, Norio Otani, Hideo Bannai, Takanori Hasegawa, Takehiro Umemura, Hideki Honda, Akio Kimura: The current status of emergency departments in secondary emergency medical institutions in Japan: a questionnaire survey. International Journal of Emergency Medicine. 2023.06; 16 (1): 40. ( PubMed , DOI )

Ryuya Edahiro, Yuya Shirai, Yusuke Takeshima, Shuhei Sakakibara, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Yu-Chen Liu, Daisuke Motooka, Yoko Naito, Ayako Takuwa, Fuminori Sugihara, Kentaro Tanaka, James B Wing, Kyuto Sonehara, Yoshihiko Tomofuji; Japan COVID-19 Task Force; Ho Namkoong, Hiromu Tanaka, Ho Lee, Koichi Fukunaga, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Atsushi Kumanogoh, Yukinori Okada: Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity. Nat Genet. 2023.05; 55 (5): 753-767. ( PubMed , DOI )

Azekawa S, Chubachi S, Asakura T, Namkoong H, Sato Y, Edahiro R, Lee H, Tanaka H, Otake S, Nakagawara K, Fukushima T, Watase M, Sakurai K, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force: Serum KL-6 levels predict clinical outcomes and are associated with MUC1 polymorphism in Japanese patients with COVID-19. BMJ open respiratory research. 2023.05; 10 (1): ( PubMed , DOI )

Yamaguchi K, Nakagawa S, Saku A, Isobe Y, Yamaguchi R, Sheridan P, Takane K, Ikenoue T, Zhu C, Miura M, Okawara Y, Nagatoishi S, Kozuka-Hata H, Oyama M, Aikou S, Ahiko Y, Shida D, Tsumoto K, Miyano S, Imoto S, Furukawa Y: Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex. iScience. 2023.04; 26 (4): 106563. ( PubMed , DOI )

Kitagawa A, Osawa T, Noda M, Kobayashi Y, Aki S, Nakano Y, Saito T, Shimizu D, Komatsu H, Sugaya M, Takahashi J, Kosai K, Takao S, Motomura Y, Sato K, Hu Q, Fujii A, Wakiyama H, Tobo T, Uchida H, Sugimachi K, Shibata K, Utsunomiya T, Kobayashi S, Ishii H, Hasegawa T, Masuda T, Matsui Y, Niida A, Soga T, Suzuki Y, Miyano S, Aburatani H, Doki Y, Eguchi H, Mori M, Nakayama KI, Shimamura T, Shibata T, Mimori K: Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma. British journal of cancer. 2023.04; 128 (12): 2206-2217. ( PubMed , DOI )

Kaburagi T, Shiba N, Yamato G, Yoshida K, Tabuchi K, Ohki K, Ishikita E, Hara Y, Shiraishi Y, Kawasaki H, Sotomatsu M, Takizawa T, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y: UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia. Genes, chromosomes & cancer. 2023.04; 62 (4): 202-209. ( PubMed , DOI )

Washimi K, Kasajima R, Shimizu E, Sato S, Okubo Y, Yoshioka E, Narimatsu H, Hiruma T, Katayama K, Yamaguchi R, Yamaguchi K, Furukawa Y, Miyano S, Imoto S, Yokose T, Miyagi Y: Histological markers, sickle-shaped blood vessels, myxoid area, and infiltrating growth pattern help stratify the prognosis of patients with myxofibrosarcoma/undifferentiated sarcoma. Scientific reports. 2023.04; 13 (1): 6744. ( PubMed , DOI )

Nakagawara K, Kamata H, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Fukushima T, Kusumoto T, Morita A, Azekawa S, Watase M, Asakura T, Masaki K, Ishii M, Endo A, Koike R, Ishikura H, Takata T, Matsushita Y, Harada N, Kokutou H, Yoshiyama T, Kataoka K, Mutoh Y, Miyawaki M, Ueda S, Ono H, Ono T, Shoko T, Muranaka H, Kawamura K, Mori N, Mochimaru T, Fukui M, Chihara Y, Nagasaki Y, Okamoto M, Amishima M, Odani T, Tani M, Nishi K, Shirai Y, Edahiro R, Ando A, Hashimoto N, Ogura S, Kitagawa Y, Kita T, Kagaya T, Kimura Y, Miyazawa N, Tsuchida T, Fujitani S, Murakami K, Sano H, Sato Y, Tanino Y, Otsuki R, Mashimo S, Kuramochi M, Hosoda Y, Hasegawa Y, Ueda T, Takaku Y, Ishiguro T, Fujiwara A, Kuwahara N, Kitamura H, Hagiwara E, Nakamori Y, Saito F, Kono Y, Abe S, Ishii T, Ohba T, Kusaka Y, Watanabe H, Masuda M, Watanabe H, Kimizuka Y, Kawana A, Kasamatsu Y, Hashimoto S, Okada Y, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Tokunaga K, Imoto S, Kitagawa Y, Kimura A, Miyano S, Hasegawa N, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force: Diagnostic significance of secondary bacteremia in patients with COVID-19. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2023.04; 29 (4): 422-426. ( PubMed , DOI )

Nakagawara K, Kamata H, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Fukushima T, Kusumoto T, Morita A, Azekawa S, Watase M, Asakura T, Masaki K, Ishii M, Endo A, Koike R, Ishikura H, Takata T, Matsushita Y, Harada N, Kokutou H, Yoshiyama T, Kataoka K, Mutoh Y, Miyawaki M, Ueda S, Ono H, Ono T, Shoko T, Muranaka H, Kawamura K, Mori N, Mochimaru T, Fukui M, Chihara Y, Nagasaki Y, Okamoto M, Amishima M, Odani T, Tani M, Nishi K, Shirai Y, Edahiro R, Ando A, Hashimoto N, Ogura S, Kitagawa Y, Kita T, Kagaya T, Kimura Y, Miyazawa N, Tsuchida T, Fujitani S, Murakami K, Sano H, Sato Y, Tanino Y, Otsuki R, Mashimo S, Kuramochi M, Hosoda Y, Hasegawa Y, Ueda T, Takaku Y, Ishiguro T, Fujiwara A, Kuwahara N, Kitamura H, Hagiwara E, Nakamori Y, Saito F, Kono Y, Abe S, Ishii T, Ohba T, Kusaka Y, Watanabe H, Masuda M, Watanabe H, Kimizuka Y, Kawana A, Kasamatsu Y, Hashimoto S, Okada Y, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Tokunaga K, Imoto S, Kitagawa Y, Kimura A, Miyano S, Hasegawa N, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force: Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study. BMC pulmonary medicine. 2023.04; 23 (1): 146. ( PubMed , DOI )

Nannya Y, Tobiasson M, Sato S, Bernard E, Ohtake S, Takeda J, Creignou M, Zhao L, Kusakabe M, Shibata Y, Nakamura N, Watanabe M, Hiramoto N, Shiozawa Y, Shiraishi Y, Tanaka H, Yoshida K, Kakiuchi N, Makishima H, Nakagawa MM, Usuki K, Watanabe M, Imada K, Handa H, Taguchi M, Kiguchi T, Ohyashiki K, Ishikawa T, Takaori-Kondo A, Tsurumi H, Kasahara S, Chiba S, Naoe T, Miyano S, Papaemmanuil E, Miyazaki Y, Hellström Lindberg E, Ogawa S: Post-azacitidine clone size predicts outcome of patients with myelodysplastic syndromes and related myeloid neoplasms. Blood advances. 2023.03; 7 (14): 3624-3636. ( PubMed , DOI )

Park H, Imoto S, Miyano S: Gene Regulatory Network-Classifier: Gene Regulatory Network-Based Classifier and Its Applications to Gastric Cancer Drug (5-Fluorouracil) Marker Identification. Journal of computational biology : a journal of computational molecular cell biology. 2023.02; 30 (2): 223-243. ( PubMed , DOI )

Makishima H, Saiki R, Nannya Y, Korotev S, Gurnari C, Takeda J, Momozawa Y, Best S, Krishnamurthy P, Yoshizato T, Atsuta Y, Shiozawa Y, Iijima-Yamashita Y, Yoshida K, Shiraishi Y, Nagata Y, Kakiuchi N, Onizuka M, Chiba K, Tanaka H, Kon A, Ochi Y, Nakagawa MM, Okuda R, Mori T, Yoda A, Itonaga H, Miyazaki Y, Sanada M, Ishikawa T, Chiba S, Tsurumi H, Kasahara S, Müller-Tidow C, Takaori-Kondo A, Ohyashiki K, Kiguchi T, Matsuda F, Jansen JH, Polprasert C, Blombery P, Kamatani Y, Miyano S, Malcovati L, Haferlach T, Kubo M, Cazzola M, Kulasekararaj AG, Godley LA, Maciejewski JP, Ogawa S: Germ line DDX41 mutations define a unique subtype of myeloid neoplasms. Blood. 2023.02; 141 (5): 534-549. ( PubMed , DOI )

Park H, Imoto S, Miyano S: Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification. PloS one. 2023; 18 (8): e0286044. ( PubMed , DOI )

Watase M, Masaki K, Chubachi S, Namkoong H, Tanaka H, Lee H, Fukushima T, Otake S, Nakagawara K, Kusumoto T, Asakura T, Kamata H, Ishii M, Hasegawa N, Oyamada Y, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Sano H, Sato Y, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force: Impact of accumulative smoking exposure and chronic obstructive pulmonary disease on COVID-19 outcomes: report based on findings from the Japan COVID-19 task force. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022.12; 128 121-127. ( PubMed , DOI )

Ho Lee, Shotaro Chubachi, Ho Namkoong, Takanori Asakura, Hiromu Tanaka, Shiro Otake, Kensuke Nakagawara, Atsuho Morita, Takahiro Fukushima, Mayuko Watase, Tatsuya Kusumoto, Katsunori Masaki, Hirofumi Kamata, Makoto Ishii, Naoki Hasegawa, Norihiro Harada, Tetsuya Ueda, Soichiro Ueda, Takashi Ishiguro, Ken Arimura, Fukuki Saito, Takashi Yoshiyama, Yasushi Nakano, Yoshikazu Mutoh, Yusuke Suzuki, Koji Murakami, Yukinori Okada, Ryuji Koike, Yuko Kitagawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, : Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force. BMC Infect Dis. 2022.12; 22 (1): 935. ( PubMed , DOI )

Butler-Laporte Guillaume, Povysil Gundula, Kosmicki Jack A., Cirulli Elizabeth T., Drivas Theodore, Furini Simone, Saad Chadi, Schmidt Axel, Olszewski Pawel, Korotko Urszula, Quinodoz Mathieu, Celik Elifnaz, Kundu Kousik, Walter Klaudia, Jung Junghyun, Stockwell Amy D., Sloofman Laura G., Jordan Daniel M., Thompson Ryan C., Del Valle Diane, Simons Nicole, Cheng Esther, Sebra Robert, Schadt Eric E., Kim-Schulze Seunghee, Gnjatic Sacha, Merad Miriam, Buxbaum Joseph D., Beckmann Noam D., Charney Alexander W., Przychodzen Bartlomiej, Chang Timothy, Pottinger Tess D., Shang Ning, Brand Fabian, Fava Francesca, Mari Francesca, Chwialkowska Karolina, Niemira Magdalena, Pula Szymon, Baillie J. Kenneth, Stuckey Alex, Salas Antonio, Bello Xabier, Pardo-Seco Jacobo, Gomez-Carballa Alberto, Rivero-Calle Irene, Martinon-Torres Federico, Ganna Andrea, Karczewski Konrad J., Veerapen Kumar, Bourgey Mathieu, Bourque Guillaume, Eveleigh Robert Jm, Forgetta Vincenzo, Morrison David, Langlais David, Lathrop Mark, Mooser Vincent, Nakanishi Tomoko, Frithiof Robert, Hultstrom Michael, Lipcsey Miklos, Marincevic-Zuniga Yanara, Nordlund Jessica, Barrett Kelly M. Schiabor, Lee William, Bolze Alexandre, White Simon, Riffle Stephen, Tanudjaja Francisco, Sandoval Efren, Neveux Iva, Dabe Shaun, Casadei Nicolas, Motameny Susanne, Alaamery Manal, Massadeh Salam, Aljawini Nora, Almutairi Mansour S., Arabi Yaseen M., Alqahtani Saleh A., Al Harthi Fawz S., Almutairi Amal, Alqubaishi Fatima, Alotaibi Sarah, Binowayn Albandari, Alsolm Ebtehal A., El Bardisy Hadeel, Fawzy Mohammad, Cai Fang, Soranzo Nicole, Butterworth Adam, Geschwind Daniel H., Arteaga Stephanie, Stephens Alexis, Butte Manish J., Boutros Paul C., Yamaguchi Takafumi N., Tao Shu, Eng Stefan, Sanders Timothy, Tung Paul J., Broudy Michael E., Pan Yu, Gonzalez Alfredo, Chavan Nikhil, Johnson Ruth, Pasaniuc Bogdan, Yaspan Brian, Smieszek Sandra, Rivolta Carlo, Bibert Stephanie, Bochud Pierre-Yves, Dabrowski Maciej, Zawadzki Pawel, Sypniewski Mateusz, Kaja Elzbieta, Chariyavilaskul Pajaree, Nilaratanakul Voraphoj, Hirankarn Nattiya, Shotelersuk Vorasuk, Pongpanich Monnat, Phokaew Chureerat, Chetruengchai Wanna, Tokunaga Katsushi, Sugiyama Masaya, Kawai Yosuke, Hasegawa Takanori, Naito Tatsuhiko, Namkoong Ho, Edahiro Ryuya, Kimura Akinori, Ogawa Seishi, Kanai Takanori, Fukunaga Koichi, Okada Yukinori, Imoto Seiya, Miyano Satoru, Mangul Serghei, Abedalthagafi Malak S., Zeberg Hugo, Grzymski Joseph J., Washington Nicole L., Ossowski Stephan, Ludwig Kerstin U., Schulte Eva C., Riess Olaf, Moniuszko Marcin, Kwasniewski Miroslaw, Mbarek Hamdi, Ismail Said I., Verma Anurag, Goldstein David B., Kiryluk Krzysztof, Renieri Alessandra, Ferreira Manuel A. R., Richards J. Brent: Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative PLOS GENETICS. 2022.11; 18 (11): e1010367. ( PubMed , DOI )

Saiki Ryunosuke, Namkoong Ho, Edahiro Ryuya, Sonehara Kyuto, Wang Qingbo S., Hasegawa Takanori, Momozawa Yukihide, Makishima Hideki, Nannya Yasuhito, Kakiuchi Nobuyuki, Terao Chikashi, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Matsuda Koichi, Morisaki Takayuki, Murakami Yoshinori, Kamatani Yoichiro, Kubo Michiaki, Kimura Akinori, Imoto Seiya, Miyano Satoru, Kanai Takanori, Fukunaga Koich, Okada Yukinori, Ogawa Seishi: Detailed Analysis of the Impact of Clonal Hematopoiesis on the Risk of Severe COVID-19 Infection BLOOD. 2022.11; 140 (Supplement 1): 5747-5748. ( DOI )

Nakagawara Kensuke, Chubachi Shotaro, Namkoong Ho, Tanaka Hiromu, Lee Ho, Azekawa Shuhei, Otake Shiro, Fukushima Takahiro, Morita Atsuho, Watase Mayuko, Sakurai Kaori, Kusumoto Tatsuya, Asakura Takanori, Masaki Katsunori, Kamata Hirofumi, Ishii Makoto, Hasegawa Naoki, Harada Norihiro, Ueda Tetsuya, Ueda Soichiro, Ishiguro Takashi, Arimura Ken, Saito Fukuki, Yoshiyama Takashi, Nakano Yasushi, Mutoh Yoshikazu, Suzuki Yusuke, Edahiro Ryuya, Murakami Koji, Sato Yasunori, Okada Yukinori, Koike Ryuji, Kitagawa Yuko, Tokunaga Katsushi, Kimura Akinori, Imoto Seiya, Miyano Satoru, Ogawa Seishi, Kanai Takanori, Fukunaga Koichi: Impact of upper and lower respiratory symptoms on COVID-19 outcomes: a multicenter retrospective cohort study RESPIRATORY RESEARCH. 2022.11; 23 (1): 315. ( PubMed , DOI )

Watanabe K, Kimura S, Seki M, Isobe T, Kubota Y, Sekiguchi M, Sato-Otsubo A, Hiwatari M, Kato M, Oka A, Koh K, Sato Y, Tanaka H, Miyano S, Kawai T, Hata K, Ueno H, Nannya Y, Suzuki H, Yoshida K, Fujii Y, Nagae G, Aburatani H, Ogawa S, Takita J: Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene. 2022.11; 41 (46): 4994-5007. ( PubMed , DOI )

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Yotaro Ochi, Ayana Kon, Toyonori Sakata, Masahiro M Nakagawa, Naotaka Nakazawa, Masanori Kakuta, Keisuke Kataoka, Haruhiko Koseki, Manabu Nakayama, Daisuke Morishita, Tatsuaki Tsuruyama, Ryunosuke Saiki, Akinori Yoda, Rurika Okuda, Tetsuichi Yoshizato, Kenichi Yoshida, Yusuke Shiozawa, Yasuhito Nannya, Shinichi Kotani, Yasunori Kogure, Nobuyuki Kakiuchi, Tomomi Nishimura, Hideki Makishima, Luca Malcovati, Akihiko Yokoyama, Kengo Takeuchi, Eiji Sugihara, Taka-Aki Sato, Masashi Sanada, Akifumi Takaori-Kondo, Mario Cazzola, Mineko Kengaku, Satoru Miyano, Katsuhiko Shirahige, Hiroshi I Suzuki, Seishi Ogawa: Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer Discov. 2020.06; 10 (6): 836-853. ( PubMed , DOI )

Munmee Dutta, Hidewaki Nakagawa, Hiroaki Kato, Kazuhiro Maejima, Shota Sasagawa, Kaoru Nakano, Aya Sasaki-Oku, Akihiro Fujimoto, Raúl Nicolás Mateos, Ashwini Patil, Hiroko Tanaka, Satoru Miyano, Takushi Yasuda, Kenta Nakai, Masashi Fujita: Whole genome sequencing analysis identifies recurrent structural alterations in esophageal squamous cell carcinoma. PeerJ. 2020.06; 8 e9294. ( PubMed , DOI )

Isidro Cortés-Ciriano, Jake June-Koo Lee, Ruibin Xi, Dhawal Jain, Youngsook L Jung, Lixing Yang, Dmitry Gordenin, Leszek J Klimczak, Cheng-Zhong Zhang, David S Pellman, Peter J Park, PCAWG Consortium (Satoru Miyano, et al.): Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nat Genet. 2020.05; Online ahead of print ( PubMed , DOI )

Minako Mori, Asuka Hira, Kenichi Yoshida, Hideki Muramatsu, Yusuke Okuno, Yuichi Shiraishi, Michiko Anmae, Jun Yasuda, Shu Tadaka, Kengo Kinoshita, Tomoo Osumi, Yasushi Noguchi, Souichi Adachi, Ryoji Kobayashi, Hiroshi Kawabata, Kohsuke Imai, Tomohiro Morio, Kazuo Tamura, Akifumi Takaori-Kondo, Masayuki Yamamoto, Satoru Miyano, Seiji Kojima, Etsuro Ito, Seishi Ogawa, Keitaro Matsuo, Hiromasa Yabe, Miharu Yabe, Minoru Takata: Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients Haematologica. 2020.04; 105 (4): 1166-1167. ( PubMed , DOI )

Misawa K, Hasegawa T, Mishima E, Jutabha P, Ouchi M, Kojima K, Kawai Y, Matsuo M, Anzai N, Nagasaki M: Contribution of Rare Variants of the SLC22A12 Gene to the Missing Heritability of Serum Urate Levels. Genetics. 2020.04; 214 (4): 1079-1090. ( PubMed , DOI )

Shunsuke Kimura, Masafumi Seki, Tomoko Kawai, Hiroaki Goto, Kenichi Yoshida, Tomoya Isobe, Masahiro Sekiguchi, Kentaro Watanabe, Yasuo Kubota, Yasuhito Nannya, Hiroo Ueno, Yusuke Shiozawa, Hiromichi Suzuki, Yuichi Shiraishi, Kentaro Ohki, Motohiro Kato, Katsuyoshi Koh, Ryoji Kobayashi, Takao Deguchi, Yoshiko Hashii, Toshihiko Imamura, Atsushi Sato, Nobutaka Kiyokawa, Atsushi Manabe, Masashi Sanada, Marc R Mansour, Akira Ohara, Keizo Horibe, Masao Kobayashi, Akira Oka, Yasuhide Hayashi, Satoru Miyano, Kenichiro Hata, Seishi Ogawa, Junko Takita: DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes. Leukemia. 2020.04; 34 (4): 1163-1168. ( PubMed , DOI )

Yao-Zhong Zhang, Arda Akdemir, Georg Tremmel, Seiya Imoto, Satoru Miyano, Tetsuo Shibuya, Rui Yamaguchi: Nanopore basecalling from a perspective of instance segmentation. BMC Bioinformatics. 2020.04; 21 (Suppl 3): 136. ( PubMed , DOI )

Fujita M, Yamaguchi R, Hasegawa T, Shimada S, Arihiro K, Hayashi S, Maejima K, Nakano K, Fujimoto A, Ono A, Aikata H, Ueno M, Hayami S, Tanaka H, Miyano S, Yamaue H, Chayama K, Kakimi K, Tanaka S, Imoto S, Nakagawa H: Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations. EBioMedicine. 2020.03; 53 102659. ( PubMed , DOI )

Sato N, Kakuta M, Hasegawa T, Yamaguchi R, Uchino E, Kobayashi W, Sawada K, Tamura Y, Tokuda I, Murashita K, Nakaji S, Imoto S, Yanagita M, Okuno Y: Metagenomic analysis of bacterial species in tongue microbiome of current and never smokers. NPJ biofilms and microbiomes. 2020.03; 6 (1): 11. ( PubMed , DOI )

Isidro Cortés-Ciriano, Jake June-Koo Lee, Ruibin Xi, Dhawal Jain, Youngsook L Jung, Lixing Yang, Dmitry Gordenin, Leszek J Klimczak, Cheng-Zhong Zhang, David S Pellman, Peter J Park, PCAWG Consortium (Satoru Miyano, et al.): Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nat Genet. 2020.03; 52 (3): 331-341. ( PubMed , DOI )

Kadir C Akdemir, Victoria T Le, Sahaana Chandran, Yilong Li, Roel G Verhaak, Rameen Beroukhim, Peter J Campbell, Lynda Chin, Jesse R Dixon, P Andrew Futreal, ,PCAWG Consortium (Satoru Miyano, et al.): Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer. Nat Genet. 2020.03; 52 (3): 294-305. ( PubMed , DOI )

Bernardo Rodriguez-Martin, Eva G Alvarez, Adrian Baez-Ortega, Jorge Zamora, Fran Supek, Jonas Demeulemeester, Martin Santamarina, Young Seok Ju, Javier Temes, Daniel Garcia-Souto, Harald Detering, Yilong Li, Jorge Rodriguez-Castro, Ana Dueso-Barroso, Alicia L Bruzos, Stefan C Dentro, Miguel G Blanco, Gianmarco Contino, Daniel Ardeljan, Marta Tojo, Nicola D Roberts, Sonia Zumalave, Paul A W Edwards, Joachim Weischenfeldt, Montserrat Puiggròs, Zechen Chong, Ken Chen, Eunjung Alice Lee, Jeremiah A Wala, Keiran Raine, Adam Butler, Sebastian M Waszak, Fabio C P Navarro, Steven E Schumacher, Jean Monlong, Francesco Maura, Niccolo Bolli, Guillaume Bourque, Mark Gerstein, Peter J Park, David C Wedge, Rameen Beroukhim, David Torrents, Jan O Korbel, Inigo Martincorena, Rebecca C Fitzgerald, Peter Van Loo, Haig H Kazazian, Kathleen H Burns, Peter J Campbell, Jose M C Tubio, PCAWG Consortium (Satoru Miyano, et al.): Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nat Genet. 2020.03; 52 (3): 306-319. ( PubMed , DOI )

Sergei Yakneen, Sebastian M Waszak, , Michael Gertz, Jan O Korbel, PCAWG Consortium (Satoru Miyano, et al.): Butler enables rapid cloud-based analysis of thousands of human genomes. Nat Biotechnol. 2020.03; 38 (3): 288-292. ( PubMed , DOI )

Takanori Hasegawa, Rui Yamaguchi, Atsushi Niida, Satoru Miyano, Seiya Imoto: Ensemble smoothers for inference of hidden states and parameters in combinatorial regulatory model J Frankl Inst. 2020.03; 357 (5): 2916-2933. ( DOI )

Akihiro Fujimoto, Masashi Fujita, Takanori Hasegawa, Jing Hao Wong, Kazuhiro Maejima, Aya Oku-Sasaki, Kaoru Nakano, Yuichi Shiraishi, Satoru Miyano, Go Yamamoto, Kiwamu Akagi, Seiya Imoto, Hidewaki Nakagawa: Comprehensive analysis of indels in whole-genome microsatellite regions and microsatellite instability across 21 cancer types. Genome Res. 2020.03; 30 (3): 334-346. ( PubMed , DOI )

Ayako Maeda-Minami, Tetsuhiro Yoshino, Kotoe Katayama, Yuko Horiba, Hiroaki Hikiami, Yutaka Shimada, Takao Namiki, Eiichi Tahara, Kiyoshi Minamizawa, Shinichi Muramatsu, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Hideki Mima, Masaru Mimura, Tomonori Nakamura, Kenji Watanabe: Discrimination of prediction models between cold-heat and deficiency-excess patterns. Complement Ther Med. 2020.03; 49 102353. ( PubMed , DOI )

Raksha Shrestha, Mamiko Sakata-Yanagimoto, Koichiro Maie, Motohiko Oshima, Masatomo Ishihara, Yasuhito Suehara, Kota Fukumoto, Yaeko Nakajima-Takagi, Hirotaka Matsui, Takayasu Kato, Hideharu Muto, Tatsuhiro Sakamoto, Manabu Kusakabe, Yasuhito Nannya, Hideki Makishima, Hiroo Ueno, Ryunosuke Saiki, Seishi Ogawa, Kenichi Chiba, Yuichi Shiraishi, Satoru Miyano, Enguerran Mouly, Olivier A Bernard, Toshiya Inaba, Haruhiko Koseki, Atsushi Iwama, Shigeru Chiba: Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status. Blood Adv. 2020.03; 4 (5): 845-854. ( PubMed , DOI )

Rika Kasajima, Rui Yamaguchi, Eigo Shimizu, Yoshinori Tamada, Atsushi Niida, George Tremmel, Takeshi Kishida, Ichiro Aoki, Seiya Imoto, Satoru Miyano, Hiroji Uemura, Yohei Miyagi: Variant analysis of prostate cancer in Japanese patients and a new attempt to predict related biological pathways Oncol Rep. 2020.03; 43 (3): 943-952. ( PubMed , DOI )

Sergei Yakneen, Sebastian M Waszak, Michael Gertz, Jan O Korbel, PCAWG Consortium (Satoru Miyano, et al.): Publisher Correction: Butler enables rapid cloud-based analysis of thousands of human genomes. Nat Biotechnol. 2020.02; Online ahead of print. ( PubMed , DOI )

Yiqun Zhang, Fengju Chen, Nuno A Fonseca, Yao He, Masashi Fujita, Hidewaki Nakagawa, Zemin Zhang, Alvis Brazma, Chad J Creighton, PCAWG Consortium (Satoru Miyano, et al.): High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nat Commun. 2020.02; 11 (1): 736. ( PubMed , DOI )

Lina Sieverling, Chen Hong, Sandra D Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M Braun, Isidro Cortés-Ciriano, Ruibin Xi, Rolf Kabbe, Peter J Park, Roland Eils, Matthias Schlesner, , Benedikt Brors, Karsten Rippe, David T W Jones, Lars Feuerbach, PCAWG Consortium (Satoru Miyano, et al.): Genomic footprints of activated telomere maintenance mechanisms in cancer. Nat Commun. 2020.02; 11 (1): 733. ( PubMed , DOI )

Makoto Hirata, Naofumi Asano, Kotoe Katayama, Akihiko Yoshida, Yusuke Tsuda, Masaya Sekimizu, Sachiyo Mitani, Eisuke Kobayashi, Motokiyo Komiyama, Hiroyuki Fujimoto, Takahiro Goto, Yukihide Iwamoto, Norifumi Naka, Shintaro Iwata, Yoshihiro Nishida, Toru Hiruma, Hiroaki Hiraga, Hirotaka Kawano, Toru Motoi, Yoshinao Oda, Daisuke Matsubara, Masashi Fujita, Tatsuhiro Shibata, Hidewaki Nakagawa, Robert Nakayama, Tadashi Kondo, Seiya Imoto, Satoru Miyano, Akira Kawai, Rui Yamaguchi, Hitoshi Ichikawa, Koichi Matsuda: Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma. Nat Commun. 2020.02; 11 (1): 1024. ( PubMed , DOI )

Esther Rheinbay, Morten Muhlig Nielsen, Federico Abascal, Jeremiah A Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj, Julian M Hess, Randi Istrup Juul, Ziao Lin, Lars Feuerbach, Radhakrishnan Sabarinathan, Tobias Madsen, Jaegil Kim, Loris Mularoni, Shimin Shuai, Andrés Lanzós, Carl Herrmann, Yosef E Maruvka, Ciyue Shen, Samirkumar B Amin, Pratiti Bandopadhayay, Johanna Bertl, Keith A Boroevich, John Busanovich, Joana Carlevaro-Fita, Dimple Chakravarty, Calvin Wing Yiu Chan, David Craft, Priyanka Dhingra, Klev Diamanti, Nuno A Fonseca, Abel Gonzalez-Perez, Qianyun Guo, Mark P Hamilton, Nicholas J Haradhvala, Chen Hong, Keren Isaev, Todd A Johnson, Malene Juul, Andre Kahles, Abdullah Kahraman, Youngwook Kim, Jan Komorowski, Kiran Kumar, Sushant Kumar, Donghoon Lee, Kjong-Van Lehmann, Yilong Li, Eric Minwei Liu, Lucas Lochovsky, Keunchil Park, Oriol Pich, Nicola D Roberts, Gordon Saksena, Steven E Schumacher, Nikos Sidiropoulos, Lina Sieverling, Nasa Sinnott-Armstrong, Chip Stewart, David Tamborero, Jose M C Tubio, Husen M Umer, Liis Uusküla-Reimand, Claes Wadelius, Lina Wadi, Xiaotong Yao, Cheng-Zhong Zhang, Jing Zhang, James E Haber, Asger Hobolth, Marcin Imielinski, Manolis Kellis, Michael S Lawrence, Christian von Mering, Hidewaki Nakagawa, Benjamin J Raphael, Mark A Rubin, Chris Sander, Lincoln D Stein, Joshua M Stuart, Tatsuhiko Tsunoda, David A Wheeler, Rory Johnson, Jüri Reimand, Mark Gerstein, Ekta Khurana, Peter J Campbell, Núria López-Bigas, Joachim Weischenfeldt, Rameen Beroukhim, Iñigo Martincorena, Jakob Skou Pedersen, Gad Getz, PCAWG Consortium. PCAWG Consortium (Satoru Miyano, et al.): Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature. 2020.02; 578 (7793): 102-111. ( PubMed , DOI )

Yilong Li, Nicola D Roberts, Jeremiah A Wala, Ofer Shapira, Steven E Schumacher, Kiran Kumar, Ekta Khurana, Sebastian Waszak, Jan O Korbel, James E Haber, Marcin Imielinski, , Joachim Weischenfeldt, Rameen Beroukhim, Peter J Campbell, PCAWG Consortium (Satoru Miyano, et al.): Patterns of somatic structural variation in human cancer genomes. Nature. 2020.02; 578 (7793): 112-121. ( PubMed , DOI )

Pan-cancer analysis of whole genomes. Nature. 2020.02; 578 (7793): 82-93. ( PubMed , DOI )

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino, Takako Kihara, Kotaro Akaki, Yoshikage Inoue, Kenji Kawada, Satoshi Nagayama, Akira Yokoyama, Shuji Yamamoto, Minoru Matsuura, Takahiro Horimatsu, Tomonori Hirano, Norihiro Goto, Yasuhide Takeuchi, Yotaro Ochi, Yusuke Shiozawa, Yasunori Kogure, Yosaku Watatani, Yoichi Fujii, Soo Ki Kim, Ayana Kon, Keisuke Kataoka, Tetsuichi Yoshizato, Masahiro M Nakagawa, Akinori Yoda, Yasuhito Nanya, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Masashi Sanada, Eiji Sugihara, Taka-Aki Sato, Takashi Maruyama, Hiroyuki Miyoshi, Makoto Mark Taketo, Jun Oishi, Ryosaku Inagaki, Yutaka Ueda, Shinya Okamoto, Hideaki Okajima, Yoshiharu Sakai, Takaki Sakurai, Hironori Haga, Seiichi Hirota, Hiroki Ikeuchi, Hiroshi Nakase, Hiroyuki Marusawa, Tsutomu Chiba, Osamu Takeuchi, Satoru Miyano, Hiroshi Seno, Seishi Ogawa: Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis. Nature. 2020.01; 577 (7789): 260-265. ( PubMed , DOI )

Masataka Taguchi, Hiroyuki Mishima, Yusuke Shiozawa, Chisa Hayashida, Akira Kinoshita, Yasuhito Nannya, Hideki Makishima, Makiko Horai, Masatoshi Matsuo, Shinya Sato, Hidehiro Itonaga, Takeharu Kato, Hiroaki Taniguchi, Daisuke Imanishi, Yoshitaka Imaizumi, Tomoko Hata, Motoi Takenaka, Yukiyoshi Moriuchi, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, Koh-Ichiro Yoshiura, Yasushi Miyazaki: Genome analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki. Haematologica. 2020.01; 105 (2): 358-365. ( PubMed , DOI )

Noriaki Sato, Masanori Kakuta, Eiichiro Uchino, Takanori Hasegawa, Ryosuke Kojima, Wataru Kobayashi, Kaori Sawada, Yoshihiro Tamura, Itoyo Tokuda, Seiya Imoto, Shigeyuki Nakaji, Koichi Murashita, Motoko Yanagita, Yasushi Okuno: The relationship between cigarette smoking and the tongue microbiome in an East Asian population. J Oral Microbiol. 2020; 12 (1): 1742527. ( PubMed , DOI )

Hasegawa Takanori, Yamaguchi Rui, Niida Atsushi, Miyano Satoru, Imoto Seiya: Ensemble smoothers for inference of hidden states and parameters in combinatorial regulatory model. JOURNAL OF THE FRANKLIN INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS. 2020; 357 (5): 2916-2933. ( DOI )

Takanori Hasegawa, Rui Yamaguchi, Masanori Kakuta, Kaori Sawada, Kenichi Kawatani, Koichi Murashita, Shigeyuki Nakaji, Seiya Imoto: Prediction of blood test values under different lifestyle scenarios using time-series electronic health record. PLoS One. 2020; 15 (3): e0230172. ( PubMed , DOI )

Atsushi Niida, Takanori Hasegawa, Hideki Innan, Tatsuhiro Shibata, Koshi Mimori, Satoru Miyano: A unified simulation model for understanding the diversity of cancer evolution. PeerJ. 2020; 8 (4): e8842. ( PubMed , DOI )

Tomoko Saito, Atsushi Niida, Ryutaro Uchi, Hidenari Hirata, Hisateru Komatsu, Shotaro Sakimura, Shuto Hayashi, Sho Nambara, Yosuke Kuroda, Shuhei Ito, Hidetoshi Eguchi, Takaaki Masuda, Keishi Sugimachi, Taro Tobo, Haruto Nishida, Tsutomu Daa, Kenichi Chiba, Yuichi Shiraishi, Tetsuichi Yoshizato, Masaaki Kodama, Tadayoshi Okimoto, Kazuhiro Mizukami, Ryo Ogawa, Kazuhisa Okamoto, Mitsutaka Shuto, Kensuke Fukuda, Yusuke Matsui, Teppei Shimamura, Takanori Hasegawa, Yuichiro Doki, Satoshi Nagayama, Kazutaka Yamada, Mamoru Kato, Tatsuhiro Shibata, Masaki Mori, Hiroyuki Aburatani, Kazunari Murakami, Yutaka Suzuki, Seishi Ogawa, Satoru Miyano, Koshi Mimori: A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer. Nat Commun. 2020; 9 (1): 2884. ( PubMed , DOI )

Sunao Shimizu, Junsei Mimura, Takanori Hasegawa, Eigo Shimizu, Seiya Imoto, Michiko Tsushima, Shuya Kasai, Hiromi Yamazaki, Yusuke Ushida, Hiroyuki Suganuma, Hirofumi Tomita, Masayuki Yamamoto, Shigeyuki Nakaji, Ken Itoh: Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging. PLoS One. 2020; 15 (8): e0236834. ( PubMed , DOI )

Nishimura A, Hirabayashi S, Hasegawa D, Yoshida K, Shiraishi Y, Ashiarai M, Hosoya Y, Fujiwara T, Harigae H, Miyano S, Ogawa S, Manabe A: Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome Pediatric Blood and Cancer. 2020; 68 (2): e28799. ( PubMed , DOI )

A Bayesian model integration for mutation calling through data partitioning 2019.11; 35 (21): 4247-4254. ( PubMed , DOI )

Alphlard-nt: Bayesian method for human leukocyte antigen genotyping and mutation calling through simultaneous analysis of normal and tumor whole-genome sequence data 2019.09; 26 (9): 923-937. ( PubMed , DOI )

Atsushi Niida, Takanori Hasegawa, Satoru Miyano: Sensitivity analysis of agent-based simulation utilizing massively parallel computation and interactive data visualization. PLoS One. 2019; 14 (3): e0210678. ( PubMed , DOI )

Comprehensive Search for Prognostic Biomarkers using PCAWG Data 2018.12; 109 291.

Masashi Fujita, Seiya Imoto, Rui Yamaguchi, Takanori Hasegawa, Shuto Hayashi, Kazuhiro Kakimi, Satoru Miyano, Hiroki Yamaue, Kazuaki Chayama, Hidewaki Nakagawa: Genomic insights into immune suppression in liver cancer CANCER SCIENCE. 2018.12; 109 640.

ALPHLARD: A Bayesian method for analyzing HLA genes from whole genome sequence data 2018.11; 19 (1): 790. ( PubMed , DOI )

Masashi Fujita, Seiya Imoto, Rui Yamaguchi, Takanori Hasegawa, Shuto Hayashi, Satoru Miyano, Hiroki Yamaue, Kazuaki Chayama, Hidewaki Nakagawa: Immuno-genomic subtype of liver cancer correlates with mechanisms of immune suppression and prognosis HUMAN GENOMICS. 2018.03; 12

Takanori Hasegawa, Kaname Kojima, Yosuke Kawai, Masao Nagasaki: Time-Series Filtering for Replicated Observations via a Kernel Approximate Bayesian Computation IEEE Trans. Signal Process. 2018; 66 (23): 6148-6161.

Tomohiro Morita, Abidur Rahman, Takanori Hasegawa, Akihiko Ozaki, Tetsuya Tanimoto: The Potential Possibility of Symptom Checker. Int J Health Policy Manag. 2017.10; 6 (10): 615-616. ( PubMed , DOI )

Takanori Hasegawa, Kaname Kojima, Yosuke Kawai, Kazuharu Misawa, Takahiro Mimori, Masao Nagasaki: AP-SKAT: highly-efficient genome-wide rare variant association test. BMC Genomics. 2016.09; 17 (1): 745. ( PubMed , DOI )

Seizo Koshiba, Ikuko Motoike, Kaname Kojima, Takanori Hasegawa, Matsuyuki Shirota, Tomo Saito, Daisuke Saigusa, Inaho Danjoh, Fumiki Katsuoka, Soichi Ogishima, Yosuke Kawai, Yumi Yamaguchi-Kabata, Miyuki Sakurai, Sachiko Hirano, Junichi Nakata, Hozumi Motohashi, Atsushi Hozawa, Shinichi Kuriyama, Naoko Minegishi, Masao Nagasaki, Takako Takai-Igarashi, Nobuo Fuse, Hideyasu Kiyomoto, Junichi Sugawara, Yoichi Suzuki, Shigeo Kure, Nobuo Yaegashi, Osamu Tanabe, Kengo Kinoshita, Jun Yasuda, Masayuki Yamamoto: The structural origin of metabolic quantitative diversity. Sci Rep. 2016.08; 6 31463. ( PubMed , DOI )

Kojima K, Kawai Y, Nariai N, Mimori T, Hasegawa T, Nagasaki M: Short tandem repeat number estimation from paired-end reads for multiple individuals by considering coalescent tree. BMC genomics. 2016.08; 17 Suppl 5 494. ( PubMed , DOI )

Junji Kurashige, Takanori Hasegawa, Atsushi Niida, Keishi Sugimachi, Niantao Deng, Kosuke Mima, Ryutaro Uchi, Genta Sawada, Yusuke Takahashi, Hidetoshi Eguchi, Masashi Inomata, Seigo Kitano, Takeo Fukagawa, Mitsuru Sasako, Hiroki Sasaki, Shin Sasaki, Masaki Mori, Kazuyoshi Yanagihara, Hideo Baba, Satoru Miyano, Patrick Tan, Koshi Mimori: Integrated Molecular Profiling of Human Gastric Cancer Identifies DDR2 as a Potential Regulator of Peritoneal Dissemination. Sci Rep. 2016.03; 6 22371. ( PubMed , DOI )

Hasegawa Takanori, Niida Atsushi, Mori Tomoya, Shimamura Teppei, Yamaguchi Rui, Miyano Satoru, Akutsu Tatsuya, Imoto Seiya: A likelihood-free filtering method via approximate Bayesian computation in evaluating biological simulation models COMPUTATIONAL STATISTICS & DATA ANALYSIS. 2016.02; 94 63-74. ( DOI )

Emi Ayada, Takanori Hasegawa, Atsushi Niida, Satoru Miyano, Seiya Imoto: Binary contingency table method for analysing gene mutation in cancer genome 2016; 12 (3): 211-226.

T. Hasegawa, S. Hayashi, E. Shimizu, S. Mizuno, R. Yamaguchi, S. Miyano, H. Nakagawa, S. Imoto: An in silico automated pipeline to identify tumor specic neoantigens from whole genome and exome sequencing data Proceeding of 12th International Symposium on Bioinformatics Research and Applications. 2016;

Emi Ayada, Atsushi Niida, Takanori Hasegawa, Satoru Miyano, Seiya Imoto: Binary Contingency Table Method for Analyzing Gene Mutation in Cancer Genome BIOINFORMATICS RESEARCH AND APPLICATIONS (ISBRA 2015). 2015.06; 9096 12-23.

Hasegawa T, Mori T, Yamaguchi R, Shimamura T, Miyano S, Imoto S, Akutsu T: Genomic data assimilation using a higher moment filtering technique for restoration of gene regulatory networks. BMC systems biology. 2015.03; 9 14. ( PubMed , DOI )

Kaname Kojima, Yosuke Kawai, Naoki Nariai, Takahiro Mimori, Takanori Hasegawa, Masao Nagasaki: Short Tandem Repeat Number Estimation from Paired-end Sequence Reads by Considering Unobserved Genealogy of Multiple Individuals BIOINFORMATICS RESEARCH AND APPLICATIONS. 2015; 9096 422-423.

Hasegawa T, Mori T, Yamaguchi R, Imoto S, Miyano S, Akutsu T: An efficient data assimilation schema for restoration and extension of gene regulatory networks using time-course observation data. Journal of computational biology : a journal of computational molecular cell biology. 2014.11; 21 (11): 785-98. ( PubMed , DOI )

Hasegawa T, Nagasaki M, Yamaguchi R, Imoto S, Miyano S: An efficient method of exploring simulation models by assimilating literature and biological observational data. Bio Systems. 2014.07; 121 54-66. ( PubMed , DOI )

Hasegawa T, Yamaguchi R, Nagasaki M, Miyano S, Imoto S: Inference of gene regulatory networks incorporating multi-source biological knowledge via a state space model with L1 regularization. PloS one. 2014; 9 (8): e105942. ( PubMed , DOI )

Takanori Hasegawa, Rui Yamaguchi, Masao Nagasaki, Seiya Imoto, Satoru Miyano: Poster: Comprehensive pharmacogenomic pathway screening by data assimilation IEEE 1st International Conference on Computational Advances in Bio and Medical Sciences(ICCABS). 2011.02; 246.

Takanori Hasegawa, Rui Yamaguchi, Masao Nagasaki, Seiya Imoto, Satoru Miyano: Comprehensive Pharmacogenomic Pathway Screening by Data Assimilation BIOINFORMATICS RESEARCH AND APPLICATIONS. 2011; 6674 160-171.

Tanaka Hiromu, Namkoong Ho, Chubachi Shotaro, Irie Shinji, Uwamino Yoshifumi, Lee Ho, Azekawa Shuhei, Otake Shiro, Nakagawara Kensuke, Fukushima Takahiro, Watase Mayuko, Kusumoto Tatsuya, Masaki Katsunori, Kamata Hirofumi, Ishii Makoto, Okada Yukinori, Takano Tomomi, Imoto Seiya, Koike Ryuji, Kimura Akinori, Miyano Satoru, Ogawa Seishi, Kanai Takanori, Sato Taka-Aki, Fukunaga Koichi: Clinical characteristics of patients with COVID-19 harboring detectable intracellular SARS-CoV-2 RNA in peripheral blood cells INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2023.10; 135 41-44. ( PubMed , DOI )

Park Heewon, 宮野 悟: 【マルチオミクス　データ駆動時代の疾患研究　がん、老化、生活習慣病　最新のオミクス統合で挑む標的探索と病態解明】(第2章)データ解析・統合のインフォマティクス　抗がん剤の感受性・耐性を説明する最適な遺伝子ネットワーク解析 実験医学. 2023.09; 41 (15): 2472-2477. ( 医中誌 )

Kusumoto Tatsuya, Chubachi Shotaro, Namkoong Ho, Tanaka Hiromu, Lee Ho, Azekawa Shuhei, Otake Shiro, Nakagawara Kensuke, Fukushima Takahiro, Morita Atsuho, Watase Mayuko, Sakurai Kaori, Asakura Takanori, Masaki Katsunori, Kamata Hirofumi, Ishii Makoto, Hasegawa Naoki, Harada Norihiro, Ueda Tetsuya, Ueda Soichiro, Ishiguro Takashi, Arimura Ken, Saito Fukuki, Yoshiyama Takashi, Nakano Yasushi, Mutoh Yoshikazu, Suzuki Yusuke, Edahiro Ryuya, Sano Hirohito, Sato Yasunori, Okada Yukinori, Koike Ryuji, Kitagawa Yuko, Tokunaga Katsushi, Kimura Akinori, Imoto Seiya, Miyano Satoru, Ogawa Seishi, Kanai Takanori, Fukunaga Koichi: Association between ABO blood group/genotype and COVID-19 in a Japanese population ANNALS OF HEMATOLOGY. 2023.08; 102 (11): 3239-3249. ( PubMed , DOI )

Park Heewon, Imoto Seiya, Miyano Satoru: PredictiveNetwork: predictive gene network estimation with application to gastric cancer drug response-predictive network analysis BMC BIOINFORMATICS. 2022.08; 23 (1): ( DOI )

宮野 悟: 【ビッグデータ解析に基づくがんの統合的理解と治療戦略】総論　ビッグデータが変えたがんの理解 Medical Science Digest. 2022.08; 48 (9): 403-405. ( 医中誌 )

Park Heewon, Yamaguchi Rui, Imoto Seiya, Miyano Satoru: Uncovering Molecular Mechanisms of Drug Resistance via Network-Constrained Common Structure Identification JOURNAL OF COMPUTATIONAL BIOLOGY. 2022.03; 29 (3): 257-275. ( DOI )

内御堂亮, 長谷川嵩矩, 若林健二: 重症新型コロナウィルス肺炎死亡予測のためのICU時系列データ解析 日本集中治療医学会学術集会(Web). 2022; 49th

内御堂 亮, 長谷川 嵩矩, 三島 有華, 塩田 修玄, 丸山 史, 長島 道生, 山内 英雄, 鵜川 豊世武, 宮野 悟, 重光 秀信: 機械学習を用いた重症新型コロナウィルス肺炎における死亡予測モデル作成の試み 日本集中治療医学会雑誌. 2021.09; 28 (Suppl.2): 337. ( 医中誌 )

三澤 計治, 三島 英換, 長谷川 嵩矩, 大内 基司, 小島 要, 河合 洋介, 松尾 雅文, 安西 尚彦, 長崎 正朗: まれな変異に重点を置いた尿酸値の遺伝率の研究 痛風と尿酸・核酸. 2021.07; 45 (1): 23-30. ( 医中誌 )

宮野 悟: 【小児外科医が学ぶ人工知能(AI)・情報伝達技術(ICT)】ゲノム医療におけるAI技術活用 小児外科. 2021.04; 53 (4): 373-377. ( 医中誌 )

鈴木 惣一朗、伊東 聰、酒井 憲一郎、稲田 由江、三吉 郁夫、石川 裕、宮野 悟 : ヒト全ゲノム解析プログラム Genomon のスーパーコンピュータ「富岳」向け最適化と性能評価 情報処理学会研究報告ハイパフォーマンスコンピューティング(HPC) . 2021.03; 2021-HPC-178 (18): 1-9.

宮野 悟: メディカルデータサイエンスの現状 日本病理学会会誌. 2021.03; 110 (1): 133. ( 医中誌 )

Park Heewon, 丸橋 弘治, 山口 類, 宮野 悟: 【新型データ駆動型サイエンスの起動】説明可能なAIによるパーソナルゲノム医療・予防の実現 医学のあゆみ. 2021.02; 276 (9): 849-853. ( 医中誌 )

三森功士, 長山聡, 長谷川嵩矩, 新井田厚司, 小林雄太, 小林雄太, 増田隆明, 鈴木穣, 柴田龍弘: 大腸癌における転移巣形成への進化とctDNAで検出可能な変異の特徴 日本がん転移学会学術集会・総会プログラム抄録集. 2021; 30th

藤井 陽一, 佐藤 悠佑, 鈴木 啓道, 吉田 健一, 白石 友一, 西松 寛明, 岡根谷 利一, 牧島 秀樹, 川合 剛人, 中川 徹, 宮野 悟, 小川 誠司, 久米 春喜: 上部尿路上皮癌の変異に基づく分子病型分類とその臨床応用の可能性 日本泌尿器科学会総会. 2020.12; 108回 464. ( 医中誌 )

藤井 陽一, 佐藤 悠佑, 鈴木 啓道, 吉田 健一, 白石 友一, 西松 寛明, 岡根谷 利一, 牧島 秀樹, 川合 剛人, 中川 徹, 宮野 悟, 小川 誠司, 久米 春喜: 上部尿路上皮癌の変異に基づく分子病型分類 日本泌尿器科学会総会. 2020.12; 108回 884. ( 医中誌 )

三澤 計治, 長谷川 嵩矩, 三島 英換, Jutabha Promsuk, 大内 基司, 小島 要, 河合 洋介, 長崎 正朗, 安西 尚彦: 尿酸値の失われた遺伝率は、レアバリアントがかなりの部分を説明する 痛風と尿酸・核酸. 2020.07; 44 (1): 86. ( 医中誌 )

宮野 悟: 【ゲノム革命-予防・医療のイノベーション】ゲノム革命の足跡と予防・医療の近未来 公衆衛生. 2020.04; 84 (4): 214-219. ( 医中誌 )

宮野 悟: 【小児血液・腫瘍疾患の最前線】診療のトピックス　人工知能と白血病の診断・治療の展望 小児科診療. 2020.04; 83 (4): 479-483. ( 医中誌 )

三澤 計治, 長谷川 嵩矩, 三島 英換, Jutabha Promsuk, 大内 基司, 小島 要, 河合 洋介, 長崎 正朗, 安西 尚彦: 尿酸値の失われた遺伝率は、レアバリアントがかなりの部分を説明する 日本痛風・核酸代謝学会総会プログラム抄録集. 2020.01; 53回 66. ( 医中誌 )

Hasegawa Takanori, Kojima Kaname, Kawai Yosuke, Nagasaki Masao: Time-Series Filtering for Replicated Observations via a Kernel Approximate Bayesian Computation IEEE TRANSACTIONS ON SIGNAL PROCESSING. 2018.12; 66 (23): 6148-6161. ( DOI )

PCAWGデータを用いた予後バイオマーカーの網羅的探索(Comprehensive Search for Prognostic Biomarkers using PCAWG Data) 2018.09; 77回 358. ( 医中誌 )

肝臓がんにおける免疫抑制機構のゲノム解析(Genomic insights into immune suppression in liver cancer) 2018.09; 77回 906. ( 医中誌 )

藤田 征志, 井元 清哉, 山口 類, 長谷川 嵩矩, 林 周斗, 宮野 悟, 松原 長秀, 冨田 尚裕, 山上 裕機, 茶山 一彰, 中川 英刀: 肝臓がんおよび大腸がんのゲノム・トランスクリプトーム解析による腫瘍免疫微小環境の特性評価 日本がん免疫学会総会プログラム・抄録集. 2018.07; 22回 152. ( 医中誌 )

三澤計治, 三澤計治, 三島英換, 大内基司, 長谷川嵩矩, 小島要, 小島要, 河合洋介, 長崎正朗, 長崎正朗, 安西尚彦, 安西尚彦, 阿部高明, 山本雅之, 山本雅之: レアバリアントが尿酸値の失われた遺伝率のかなりの割合を説明する 日本人類遺伝学会大会プログラム・抄録集. 2018; 63rd

長谷川嵩矩, 新井田厚司, 山口類, 井元清哉: 状態空間モデルを用いた時系列ヘルスケアデータの解析と応用 統計関連学会連合大会講演報告集. 2018; 2018

長谷川嵩矩, 新井田厚司, 山口類, 井元清哉: L1正則化付き状態空間モデルを用いた健診結果の将来予測 統計関連学会連合大会講演報告集. 2017; 2017

長谷川嵩矩, 新井田厚司, 山口類, 井元清哉: 機械学習を用いた時系列ヘルスケアデータの解析と応用 統計関連学会連合大会講演報告集. 2019; 2019