卓越研究部門

692  件  
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  1. Leyva-Castillo JM, Vega-Mendoza D, Strakosha M, Deng L, Choi S, Miyake K, Karasuyama H, Chiu IM, Phipatanakul W, Geha RS: Basophils are important for the development of allergic skin inflammation. The Journal of allergy and clinical immunology. 2024.02; ( PubMed , DOI )

  2. Miyake K, Ito J, Takahashi K, Nakabayashi J, Brombacher F, Shichino S, Yoshikawa S, Miyake S, Karasuyama H: Single-cell transcriptomics identifies the differentiation trajectory from inflammatory monocytes to pro-resolving macrophages in a mouse skin allergy model. Nature communications. 2024.02; 15 (1): 1666. ( PubMed , DOI )

  3. Strakosha M, Vega-Mendoza D, Kane J, Jain A, Sun L, Rockowitz S, Elkins M, Miyake K, Chou J, Karasuyama H, Geha RS, Leyva-Castillo JM: Basophils play a protective role in the recovery of skin barrier function from mechanical injury in mice. The Journal of investigative dermatology. 2024.01; ( PubMed , DOI )

  4. Nelson M LaMarche, Samarth Hegde, Matthew D Park, Barbara B Maier, Leanna Troncoso, Jessica Le Berichel, Pauline Hamon, Meriem Belabed, Raphaël Mattiuz, Clotilde Hennequin, Theodore Chin, Amanda M Reid, Iván Reyes-Torres, Erika Nemeth, Ruiyuan Zhang, Oakley C Olson, Deborah B Doroshow, Nicholas C Rohs, Jorge E Gomez, Rajwanth Veluswamy, Nicole Hall, Nicholas Venturini, Florent Ginhoux, Zhaoyuan Liu, Mark Buckup, Igor Figueiredo, Vladimir Roudko, Kensuke Miyake, Hajime Karasuyama, Edgar Gonzalez-Kozlova, Sacha Gnjatic, Emmanuelle Passegué, Seunghee Kim-Schulze, Brian D Brown, Fred R Hirsch, Brian S Kim, Thomas U Marron, Miriam Merad: An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. Nature. 2024.01; 625 (7993): 166-174. ( PubMed , DOI )

  1. Nagashima N, Ugajin T, Miyake K, Walls AF, Namiki T, Yokozeki H, Karasuyama H, Okiyama N: Cutaneous basophil infiltration in atopic dermatitis is associated with abundant epidermal infiltration of helper T cells: A preliminary retrospective study. The Journal of dermatology. 2023.10; 51 (1): 130-134. ( PubMed , DOI )

  2. Kazufusa Takahashi, Kensuke Miyake, Junya Ito, Hinano Shimamura, Tadahiro Suenaga, Hajime Karasuyama, Kenichi Ohashi: Topical application of a PDE4 inhibitor ameliorates atopic dermatitis through inhibition of basophil IL-4 production. J Invest Dermatol. 2023.10; ( PubMed , DOI )

  3. Shota Suzuki, Kotaro Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Atsunori Oshima, Yoshinori Fujiyoshi: Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding. Nat Commun. 2023.09; 14 (1): 5899. ( PubMed , DOI )

  4. Shunsuke Imai, Hiroshi Suzuki, Yoshinori Fujiyoshi, Ichio Shimada: Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun. 2023.08; 14 (1): 4977. ( PubMed , DOI )

  5. Katsumasa Irie, Yoshinori Oda, Takashi Sumikama, Atsunori Oshima, Yoshinori Fujiyoshi: The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel. Nat Commun. 2023.07; 14 (1): 4236. ( PubMed , DOI )

  6. Akiko Kamegawa, Shota Suzuki, Hiroshi Suzuki, Kouki Nishikawa, Nobutaka Numoto, Yoshinori Fujiyoshi: Structural analysis of the water channel AQP2 by single-particle cryo-EM. J Struct Biol. 2023.06; 215 107984. ( PubMed , DOI )

  7. Kensuke Miyake, Junya Ito, Jun Nakabayashi, Shigeyuki Shichino, Kenji Ishiwata, Hajime Karasuyama: Single cell transcriptomics clarifies the basophil differentiation trajectory and identifies pre-basophils upstream of mature basophils. Nat Commun. 2023.05; 14 (1): 2694. ( PubMed , DOI )

  8. Daisuke Kozai, Nobutaka Numoto, Kouki Nishikawa, Akiko Kamegawa, Shohei Kawasaki, Yoko Hiroaki, Katsumasa Irie, Atsunori Oshima, Hiroyuki Hanzawa, Kousei Shimada, Yutaka Kitano, Yoshinori Fujiyoshi: Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit J Mol Biol. 2023.03; 168049. ( PubMed , DOI )

  9. Pellefigues C, Karasuyama H: Editorial: The fundamental biology of basophils in health and disease. Frontiers in immunology. 2023; 14 1292279. ( PubMed , DOI )

  1. Hashimoto T, Yokozeki H, Karasuyama H, Satoh T: IL-31-generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin. The Journal of allergy and clinical immunology. 2022.11; 151 (3): 737-746.e6. ( PubMed , DOI )

  2. Yukihiro Tanimura, Yoko Hiroaki, Masahiro Mori, Yoshinori Fujiyoshi: Cell-based flow cytometry assay for simultaneous detection of multiple autoantibodies in a single serum sample. Anal Biochem. 2022.08; 650 114721. ( PubMed , DOI )

  3. Katerina Naydenova, Akiko Kamegawa, Mathew J Peet, Richard Henderson, Yoshinori Fujiyoshi, Christopher J Russo: On the reduction in the effects of radiation damage to two-dimensional crystals of organic and biological molecules at liquid-helium temperature. Ultramicroscopy. 2022.07; 237 113512. ( PubMed , DOI )

  4. Inaba K, Higashiyama M, Watanabe C, Tomioka A, Ito S, Tanemoto R, Mizoguchi A, Nishii S, Wada A, Sugihara N, Hanawa Y, Horiuchi K, Akita Y, Okada Y, Kurihara C, Narimatsu K, Komoto S, Tomita K, Karasuyama H, Satoh T, Hokari R: Basophils play a proinflammatory role in oxazolone-induced chronic intestinal inflammation. Journal of gastroenterology and hepatology. 2022.07; 37 (9): 1768-1775. ( PubMed , DOI )

  5. Maki Kuzuya, Hidemi Hirano, Kenichi Hayashida, Masakatsu Watanabe, Kazumi Kobayashi, Tohru Terada, Md Iqbal Mahmood, Florence Tama, Kazutoshi Tani, Yoshinori Fujiyoshi, Atsunori Oshima: Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci Signal. 2022.02; 15 (720): eabg6941. ( PubMed , DOI )

  6. Kensuke Miyake, Junya Ito, Hajime Karasuyama: Role of Basophils in a Broad Spectrum of Disorders. Front Immunol. 2022; 13 902494. ( PubMed , DOI )

  7. Tchen J, Simon Q, Chapart L, Pellefigues C, Karasuyama H, Miyake K, Blank U, Benhamou M, Daugas E, Charles N: CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development. Frontiers in immunology. 2022; 13 900532. ( PubMed , DOI )

  1. van der Vlist M, Raoof R, Willemen HLDM, Prado J, Versteeg S, Martin Gil C, Vos M, Lokhorst RE, Pasterkamp RJ, Kojima T, Karasuyama H, Khoury-Hanold W, Meyaard L, Eijkelkamp N: Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain. Neuron. 2021.12; 110 (4): 613-+. ( PubMed , DOI )

  2. Karasuyama Hajime, Shibata Sho, Yoshikawa Soichiro, Miyake Kensuke: 免疫系において軽視されてきた非主流派の好塩基球はついに脚光を浴びる場所にやってきた(Basophils, a neglected minority in the immune system, have come into the limelight at last) International Immunology. 2021.12; 33 (12): 809-813. ( 医中誌 )

  3. Leyva-Castillo JM, Das M, Kane J, Strakosha M, Singh S, Wong DSH, Horswill AR, Karasuyama H, Brombacher F, Miller LS, Geha RS: Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. JCI insight. 2021.11; 6 (21): ( PubMed , DOI )

  4. Yukako Oda, Chisato Takahashi, Shota Harada, Shun Nakamura, Daxiao Sun, Kazumi Kiso, Yuko Urata, Hitoshi Miyachi, Yoshinori Fujiyoshi, Alf Honigmann, Seiichi Uchida, Yasushi Ishihama, Fumiko Toyoshima: Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation. Sci Adv. 2021.11; 7 (47): eabj6895. ( PubMed , DOI )

  5. Kensuke Miyake, Sho Shibata, Soichiro Yoshikawa, Hajime Karasuyama: Basophils and their effector molecules in allergic disorders. Allergy. 2021.06; 76 (6): 1693-1706. ( PubMed , DOI )

  6. Nagaishi T, Watabe T, Kotake K, Kumazawa T, Aida T, Tanaka K, Ono R, Ishino F, Usami T, Miura T, Hirakata S, Kawasaki H, Tsugawa N, Yamada D, Hirayama K, Yoshikawa S, Karasuyama H, Okamoto R, Watanabe M, Blumberg RS, Adachi T: Immunoglobulin A-specific deficiency induces spontaneous inflammation specifically in the ileum. Gut. 2021.05; 71 (3): 487-496. ( PubMed , DOI )

  7. Karasuyama H, Shibata S, Yoshikawa S, Miyake K: Basophils, a neglected minority in the immune system, have come into the limelight at last. International immunology. 2021.05; 33 (12): 809-813. ( PubMed , DOI )

  8. Kensuke Miyake, Hajime Karasuyama: The Role of Trogocytosis in the Modulation of Immune Cell Functions. Cells. 2021.05; 10 (5): ( PubMed , DOI )

  9. Anaïs Wanet, Mahmoud A Bassal, Sweta B Patel, Francisco Marchi, Samanta A Mariani, Nouraiz Ahmed, Haoran Zhang, Marta Borchiellini, Sisi Chen, Junyan Zhang, Annalisa Di Ruscio, Kensuke Miyake, Mindy Tsai, Anuya Paranjape, Shin-Young Park, Hajime Karasuyama, Timm Schroeder, Elaine Dzierzak, Stephen J Galli, Daniel G Tenen, Robert S Welner: E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates. Sci Immunol. 2021.02; 6 (56): ( PubMed , DOI )

  10. Hiroki Yamaguchi, Akiko Kamegawa, Kunio Nakata, Tatsuki Kashiwagi, Yoshinori Fujiyoshi, Kazutoshi Tani, Toshimi Mizukoshi: Leucine Dehydrogenase: Structure and Thermostability. Subcell Biochem. 2021; 96 355-372. ( PubMed , DOI )

  1. A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms 2020.10; 183 (3): 802-817.e24. ( DOI )

  2. Ito Junya, Miyake Kensuke, Shichino Shigeyuki, Yamanishi Yoshinori, Karasuyama Hajime: Identification of two distinct subpopulations among basophils in the bone marrow(和訳中) アレルギー. 2020.10; 69 (臨時増刊号): 133. ( 医中誌 )

  3. Miyake Kensuke, Ito Junya, Takahashi Kazufusa, Yoshikawa Soichiro, Yamanishi Yoshinori, Karasuyama Hajime: Regulation of immune cells　Monocyte-derived M2-like macrophages induced by activated basophils dampen IL-1α-mediated aggravation of allergic inflammation(和訳中) アレルギー. 2020.10; 69 (臨時増刊号): 91. ( 医中誌 )

  4. Aihara Yoshiko, Fukuda Yota, Takizawa Akiyoshi, Osakabe Naomi, Aida Tomomi, Tanaka Kohichi, Yoshikawa Soichiro, Karasuyama Hajime, Adachi Takahiro: 生体内イメージングを用いた腸管における機械的ストレス媒介Ca2+シグナル伝達の可視化(Visualization of mechanical stress-mediated Ca2+ signaling in the gut using intravital imaging) Bioscience of Microbiota, Food and Health. 2020.10; 39 (4): 209-218. ( 医中誌 )

  5. Karasuyama Hajime, Miyake Kensuke, Yoshikawa Soichiro: Immunobiology of Acquired Resistance to Ticks FRONTIERS IN IMMUNOLOGY. 2020.10; 11 601504. ( PubMed , DOI )

  6. Yamanishi Y, Mogi K, Takahashi K, Miyake K, Yoshikawa S, Karasuyama H: Skin-infiltrating basophils promote atopic dermatitis-like inflammation via IL-4 production in mice. Allergy. 2020.10; 75 (10): 2613-2622. ( PubMed , DOI )

  7. Yoshikawa S, Miyake K, Kamiya A, Karasuyama H: The role of basophils in acquired protective immunity to tick infestation. Parasite immunology. 2020.10; 43 (5): e12804. ( PubMed , DOI )

  8. Hanayo Nakanishi, Tomohiro Nishizawa, Katsumori Segawa, Osamu Nureki, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe: Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep. 2020.09; 32 (13): 108208. ( PubMed , DOI )

  9. Yang Yue, Nagai Shigenori, Kang Siwen, Xia Yulong, Kawano Yohei, Miyake Kensuke, Karasuyama Hajime, Azuma Miyuki: 反復抗原塗布後に舌下粘膜に現れたCD206+マクロファージの免疫寛容原性(Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting) International Immunology. 2020.08; 32 (8): 509-518. ( 医中誌 )

  10. Irie Katsumasa, Shimomura Takushi, Yonekawa Yoshiki, Nagura Hitoshi, Tateyama Michihiro, Fujiyoshi Yoshinori: 天然の原核生物由来カルシウムチャネルにおけるイオン透過選択性の進化とその決定残基の同定(The selectivity determinant and evolution of a native prokaryotic voltage-dependent calcium channel) 生物物理. 2020.08; 60 (Suppl.1-2): S248. ( 医中誌 )

  11. Shimada Atsuhiro, Kozai Daisuke, Nishikawa Kouki, Fujiyoshi Yoshinori, Sho Gyokucho, Mizutani Takumi, Tani Kazutoshi: クライオ電子顕微鏡を用いたシトクロム酸化酵素とシトクロムcの複合体構造解析(The structural analysis of cytochrome c oxidase complexed with cytochrome c using cryo-electron microscopy) 生物物理. 2020.08; 60 (Suppl.1-2): S158. ( 医中誌 )

  12. Hanayo Nakanishi, Katsumasa Irie, Katsumori Segawa, Kazuya Hasegawa, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe: Crystal structure of a human plasma membrane phospholipid flippase. J Biol Chem. 2020.07; 295 (30): 10180-10194. ( PubMed , DOI )

  13. Nishimura Yuya, Fukuda Yota, Okonogi Toya, Yoshikawa Soichiro, Karasuyama Hajime, Osakabe Naomi, Ikegaya Yuji, Sasaki Takuya, Adachi Takahiro: Dual real-time in vivo monitoring system of the brain-gut axis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020.04; 524 (2): 340-345. ( PubMed , DOI )

  14. New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins. 2020.03; 9 ( PubMed , DOI )

  15. Yue Yang, Shigenori Nagai, Siwen Kang, Yulong Xia, Yohei Kawano, Kensuke Miyake, Hajime Karasuyama, Miyuki Azuma: Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting. Int. Immunol.. 2020.03; ( PubMed , DOI )

  16. Lin Yu-Hsien, Tahara-Hanaoka Satoko, Nagai Kei, Yoshikawa Soichiro, Kubo Masato, Shibayama Shiro, Karasuyama Hajime, Shibuya Akira: マウスにおける好塩基球上のAllergin-1による経口アレルゲン誘導アナフィラキシーの選択的抑制(Selective suppression of oral allergen-induced anaphylaxis by Allergin-1 on basophils in mice) International Immunology. 2020.03; 32 (3): 213-219. ( 医中誌 )

  17. B. Burendei, R. Shinozaki, M. Watanabe, T. Terada, K. Tani, Y. Fujiyoshi and A. Oshima: Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci. Adv.. 2020.02; 6 (7): ( DOI )

  18. Takushi Shimomura, Yoshiki Yonekawa, Hitoshi Nagura, Michihiro Tateyama, Yoshinori Fujiyoshi, Katsumasa Irie: A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence. Elife. 2020.02; 9 ( PubMed , DOI )

  19. Aihara Yoshiko, Fukuda Yota, Takizawa Akiyoshi, Osakabe Naomi, Aida Tomomi, Tanaka Kohichi, Yoshikawa Soichiro, Karasuyama Hajime, Adachi Takahiro: Visualization of mechanical stress-mediated Ca2+ signaling in the gut using intravital imaging BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH. 2020; 39 (4): 209-218. ( PubMed , DOI )

  1. Lin YH, Tahara-Hanaoka S, Nagai K, Yoshikawa S, Kubo M, Shibayama S, Karasuyama H, Shibuya A: Selective suppression of oral allergen-induced anaphylaxis by Allergin-1 on basophils in mice. International Immunology. 2019.12; 32 (3): 213-219. ( PubMed , DOI )

  2. Yoshikawa S., Oh-hora M., Hashimoto R., Miyake K., Adachi T., Kawano Y., Yamanishi Y., Kamiya A., Karasuyama H.: Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated basophils EUROPEAN JOURNAL OF IMMUNOLOGY. 2019.10; 49 584-585.

  3. Kashiwakura J, Ando T, Karasuyama H, Kubo M, Matsumoto K, Matsuda T, Kawakami T: The basophil-IL-4-mast cell axis is required for food allergy. Allergy. 2019.10; 74 (10): 1992-1996. ( PubMed , DOI )

  4. Adachi Takahiro, Yoshikawa Soichiro, Tezuka Hiroyuki, Tsuji Noriko M., Ohteki Toshiaki, Karasuyama Hajime, Kumazawa Toshihiko: プロポリスは免疫細胞におけるCa2+シグナル伝達を誘導する(Propolis induces Ca2+ signaling in immune cells) Bioscience of Microbiota, Food and Health. 2019.10; 38 (4): 141-149. ( 医中誌 )

  5. K. Yamamoto, V. Dubey, K. Irie, H. Nakanishi, H. Khandelia, Y. Fujiyoshi and K. Abe: A single K+-binding site in the crystal structure of the gastric proton pump. eLife. 2019.08; 8 ( DOI )

  6. Balam S, Schiechl-Brachner G, Buchtler S, Halbritter D, Schmidbauer K, Talke Y, Neumayer S, Salewski NJ, Winter F, Karasuyama H, Yamanishi Y, Renner K, Geissler EK, Mack M: IL-3 Triggers Chronic Rejection of Cardiac Allografts by Activation of Infiltrating Basophils. Journal of Immunology. 2019.06; 202 (12): 3514-3523. ( PubMed , DOI )

  7. Soichiro Yoshikawa, Masatsugu Oh-Hora, Ryota Hashimoto, Toshihisa Nagao, Louis Peters, Mayumi Egawa, Takuya Ohta, Kensuke Miyake, Takahiro Adachi, Yohei Kawano, Yoshinori Yamanishi, Hajime Karasuyama: Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils. Sci Signal. 2019.04; 12 (576): ( PubMed , DOI )

  8. Hashimoto T, Satoh T, Karasuyama H, Yokozeki H: Amphiregulin from basophils amplifies basophil-mediated chronic skin inflammation. The Journal of investigative dermatology. 2019.03; ( PubMed , DOI )

  9. Shun Nakamura, Katsumasa Irie, Hiroo Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Yasunori Saitoh, Atsushi Tamura, Sachiko Tsukita & Yoshinori Fujiyoshi: Morphologic determinant of tight junctions revealed by claudin-3 structures Nature Communications. 2019.02; 10 816. ( DOI )

  10. Toshihisa Nagao, Yoshinori Yamanishi, Kensuke Miyake, Mio Teranishi, Saori Takahashi, Soichiro Yoshikawa, Yohei Kawano, Hajime Karasuyama: Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice. Int. Immunol.. 2019.02; 31 (1): 41-49. ( PubMed , DOI )

  11. Piliponsky AM, Shubin NJ, Lahiri AK, Truong P, Clauson M, Niino K, Tsuha AL, Nedospasov SA, Karasuyama H, Reber LL, Tsai M, Mukai K, Galli SJ: Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice. Nature Immunology. 2019.02; 20 (2): 129-140. ( PubMed , DOI )

  12. Yamaguchi Hiroki, Kamegawa Akiko, Nakata Kunio, Kashiwagi Tatsuki, Mizukoshi Toshimi, Fujiyoshi Yoshinori, Tani Kazutoshi: Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy JOURNAL OF STRUCTURAL BIOLOGY. 2019.01; 205 (1): 11-21. ( PubMed , DOI )

  13. Nagao Toshihisa, Yamanishi Yoshinori, Miyake Kensuke, Teranishi Mio, Takahashi Saori, Yoshikawa Soichiro, Kawano Yohei, Karasuyama Hajime: マウスにて好塩基球媒介性アレルギー誘発相において、蛋白質の凝集によって蛋白質がアレルゲン化する(Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice) International Immunology. 2019.01; 31 (1): 41-49. ( 医中誌 )

  14. Tateishi T., Shibata S., Karasuyama H., Miyazaki Y.: Basophil Depletion Leads to Promotion of the Lung Fibrosis in Bleomycin-Mouse Model AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019; 199

  15. Adachi Takahiro, Yoshikawa Soichiro, Tezuka Hiroyuki, Tsuji Noriko M., Ohteki Toshiaki, Karasuyama Hajime, Kumazawa Toshihiko: Propolis induces Ca2+ signaling in immune cells BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH. 2019; 38 (4): 141-149. ( DOI )

  1. Sho Shibata, Kensuke Miyake, Tomoya Tateishi, Soichiro Yoshikawa, Yoshinori Yamanishi, Yasunari Miyazaki, Naohiko Inase, Hajime Karasuyama: Basophils trigger emphysema development in a murine model of COPD through IL-4-mediated generation of MMP-12-producing macrophages. Proc. Natl. Acad. Sci. U.S.A.. 2018.12; 115 (51): 13057-13062. ( PubMed , DOI )

  2. Hajime Karasuyama, Yuya Tabakawa, Takuya Ohta, Takeshi Wada, Soichiro Yoshikawa: Crucial Role for Basophils in Acquired Protective Immunity to Tick Infestation. Front Physiol. 2018.12; 9 1769. ( PubMed , DOI )

  3. Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. 2018.10; 175 (3): 822-834. ( PubMed , DOI )

  4. Karasuyama Hajime, Miyake Kensuke, Yoshikawa Soichiro, Kawano Yohei, Yamanishi Yoshinori: How do basophils contribute to T(h)2 cell differentiation and allergic responses? INTERNATIONAL IMMUNOLOGY. 2018.09; 30 (9): 391-396. ( PubMed , DOI )

  5. Karasuyama Hajime, Miyake Kensuke, Yoshikawa Soichiro, Kawano Yohei, Yamanishi Yoshinori: 好塩基球はいかにしてTh2細胞分化およびアレルギー反応に寄与するか?(How do basophils contribute to Th2 cell differentiation and allergic responses?) International Immunology. 2018.09; 30 (9): 391-396. ( 医中誌 )

  6. Hajime Karasuyama, Kensuke Miyake, Soichiro Yoshikawa, Yoshinori Yamanishi: Multifaceted roles of basophils in health and disease. J. Allergy Clin. Immunol.. 2018.08; 142 (2): 370-380. ( PubMed , DOI )

  7. Yuya Tabakawa, Takuya Ohta, Soichiro Yoshikawa, Elisabeth J Robinson, Kayoko Yamaji, Kenji Ishiwata, Yohei Kawano, Kensuke Miyake, Yoshinori Yamanishi, Hiroshi Ohtsu, Takahiro Adachi, Naohiro Watanabe, Hirotaka Kanuka, Hajime Karasuyama: Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice. Front Immunol. 2018.07; 9 1540. ( PubMed , DOI )

  8. Yohei Kawano, Georg Petkau, Christina Stehle, Pawel Durek, Gitta Anne Heinz, Kousuke Tanimoto, Hajime Karasuyama, Mir-Farzin Mashreghi, Chiara Romagnani, Fritz Melchers: Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors. Blood. 2018.05; 131 (18): 2026-2035. ( PubMed , DOI )

  9. Taro Watabe, Takashi Nagaishi, Naoya Tsugawa, Yudai Kojima, Nisha Jose, Akinori Hosoya, Michio Onizawa, Yasuhiro Nemoto, Shigeru Oshima, Tetsuya Nakamura, Hajime Karasuyama, Takahiro Adachi, Mamoru Watanabe: B cell activation in the cecal patches during the development of an experimental colitis model. Biochem. Biophys. Res. Commun.. 2018.02; 496 (2): 367-373. ( PubMed , DOI )

  10. Christophe Pellefigues, Barbara Dema, Yasmine Lamri, Fanny Saidoune, Nathalie Chavarot, Charlotte Lohéac, Emeline Pacreau, Michael Dussiot, Caroline Bidault, Florian Marquet, Mathieu Jablonski, Jonathan M Chemouny, Fanny Jouan, Antoine Dossier, Marie-Paule Chauveheid, Delphine Gobert, Thomas Papo, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles: Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs. Nat Commun. 2018.02; 9 (1): 725. ( PubMed , DOI )

  1. Kojima Toshiyuki, Yoshikawa Soichiro, Yamanishi Yoshinori, Karasuyama Hajime: Mucosal-Skin Immunity(2) Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 3-F. ( 医中誌 )

  2. Takahiro Adachi, Yoshikawa Soichiro, Karasuyama Hajime: B cell development and function Intravital imaging of Ca2+ signals in lymphocytes of the Ca2+ biosensor YC3.60 transgenic mice(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 3-E. ( 医中誌 )

  3. Karasuyama Hajime: Allergy: state-of-the-art Emerging roles of basophils in allergic inflammation and immune regulation(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): S1-4. ( 医中誌 )

  4. Miyake Kensuke, Shiozawa Nozomu, Nagao Toshihisa, Yoshikawa Soichiro, Yamanishi Yoshinori, Karasuyama Hajime: Granulocyte & Mast cells Basophils exert antigen presentation via trogocytosis-mediated acquisition of peptide-MHC class II complexes from dendritic cells(DCs)(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 3-H. ( 医中誌 )

  5. SHIBATA Sho, MIYAKE Kensuke, YOSHIKAWA Soichiro, KAWANO Yohei, YAMANISHI Yoshinori, KARASUYAMA Hajime: Allergy: Lower airway allergic inflammation Monocyte-derived macrophages in the lung contribute to the development of pulmonary emphysema through MMP-12 production in a mouse model of COPD(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 1-A. ( 医中誌 )

  6. Yamanishi Yoshinori, Iki Misako, Tanaka Kensei, Deki Hayato, Fujimaki Mio, Miyake Kensuke, Yoshikawa Soichiro, Kawano Yohei, Sato Shingo, Karasuyama Hajime: Allergy: Allergic dermatitis, food allergy and allergic conjunctivitis Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 2-G. ( 医中誌 )

  7. Takuya Ohta, Soichiro Yoshikawa, Yuya Tabakawa, Kayoko Yamaji, Kenji Ishiwata, Hiroshi Shitara, Choji Taya, Masatsugu Oh-Hora, Yohei Kawano, Kensuke Miyake, Yoshinori Yamanishi, Hiromichi Yonekawa, Naohiro Watanabe, Hirotaka Kanuka, Hajime Karasuyama: Skin CD4+ Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites. Front Immunol. 2017.10; 8 1348. ( PubMed , DOI )

  8. Barbara Dema, Yasmine Lamri, Christophe Pellefigues, Emeline Pacreau, Fanny Saidoune, Caroline Bidault, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles: Basophils contribute to pristane-induced Lupus-like nephritis model. Sci Rep. 2017.08; 7 (1): 7969. ( PubMed , DOI )

  9. Miyake Kensuke, Karasuyama Hajime: アレルギー性炎症における好塩基球の新たな役割(Beyond Th2, More than ILC2　Emerging roles of basophils in allergic inflammation) Allergology International. 2017.07; 66 (3): 382-391. ( 医中誌 )

  10. Sumika Toyama, Naoko Okada, Akio Matsuda, Hideaki Morita, Hirohisa Saito, Takao Fujisawa, Susumu Nakae, Hajime Karasuyama, Kenji Matsumoto: Human eosinophils constitutively express a unique serine protease, PRSS33. Allergol Int. 2017.07; 66 (3): 463-471. ( PubMed , DOI )

  11. Tomoyuki Bando, Setsuko Fujita, Naoko Nagano, Soichiro Yoshikawa, Yoshinori Yamanishi, Masashi Minami, Hajime Karasuyama: Differential usage of COX-1 and COX-2 in prostaglandin production by mast cells and basophils. Biochem Biophys Rep. 2017.07; 10 82-87. ( PubMed , DOI )

  12. Yoshinori Yamanishi, Kensuke Miyake, Misako Iki, Hidemitsu Tsutsui, Hajime Karasuyama: Recent advances in understanding basophil-mediated Th2 immune responses. Immunol. Rev.. 2017.07; 278 (1): 237-245. ( PubMed , DOI )

  13. Kensuke Miyake, Hajime Karasuyama: Emerging roles of basophils in allergic inflammation. Allergol. Int.. 2017.07; 66 (3): 382-391. ( PubMed , DOI )

  14. Yamanishi Yoshinori, Iki Misako, Tanaka Kensei, Deki Hayato, Fujimaki Mio, Sato Shingo, Yoshikawa Soichiro, Karasuyama Hajime: IgE介在性慢性アレルギー性炎症において好塩基球性トリプターゼmMCP-11は重要な役割を果たす(Basophil tryptase mMCP-11 plays a crucial role in the IgE-mediated chronic allergic inflammation) アレルギー. 2017.05; 66 (4-5): 520. ( 医中誌 )

  15. Kaori Mukai, Hajime Karasuyama, Kenji Kabashima, Masato Kubo, Stephen J Galli: Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4+ T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis. Infect. Immun.. 2017.04; 85 (5): e00053-17. ( PubMed , DOI )

  16. Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L Reber, Stephen J Galli: Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis. J. Allergy Clin. Immunol.. 2017.02; 139 (2): 584-596.e10. ( PubMed , DOI )

  17. Hidemitsu Tsutsui, Yoshinori Yamanishi, Hiromi Ohtsuka, Shingo Sato, Soichiro Yoshikawa, Hajime Karasuyama: The Basophil-specific Protease mMCP-8 Provokes an Inflammatory Response in the Skin with Microvascular Hyperpermeability and Leukocyte Infiltration. J. Biol. Chem.. 2017.01; 292 (3): 1061-1067. ( PubMed , DOI )

  18. Kensuke Miyake, Nozomu Shiozawa, Toshihisa Nagao, Soichiro Yoshikawa, Yoshinori Yamanishi, Hajime Karasuyama: Trogocytosis of peptide-MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils. Proc. Natl. Acad. Sci. U.S.A.. 2017.01; 114 (5): 1111-1116. ( PubMed , DOI )

  1. Iki, M., Tanaka, K., Deki, H. Fujimaki, M., Sato, S., Yoshikawa, S., Yamanishi, Y., Karasuyama, K.: Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation in mice. Blood. 2016.12; 128 (25): 2909-2918. ( PubMed , DOI )

  2. Toshiyuki Kojima, Kiichiro Tsuchiya, Shinji Ikemizu, Soichiro Yoshikawa, Yoshinori Yamanishi, Mamoru Watanabe, Hajime Karasuyama: Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R. Sci Rep. 2016.11; 6 36457. ( PubMed , DOI )

  3. Venturelli, N., Lexmond, W. S., Ohsaki, A., Nurko, S., Karasuyama, H., Fiebiger, E., Oyoshi, M. K.: Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice. J. Allergy Clin. Immunol.. 2016.11; 138 (5): 1367-1380.e5. ( PubMed , DOI )

  4. Horiguchi, K., Yoshikawa, S., Saito, A., Haddad, S., Ohta, T., Miyake, K., Yamanishi, Y., Karasuyama, H.: Real-time imaging of mast cell degranulation in vitro and in vivo. Biochem. Biophys. Res. Commun.. 2016.10; 479 (3): 517-522. ( PubMed , DOI )

  5. Schiechl, G., Hermann, F.J., Rodriguez Gomez, M., Kutzi, S., Schmidbauer, K., Talke, Y., Neumayer, S., Goebel, N., Renner, K., Brühl, H., Karasuyama, H., Obata-Ninomiya, K., K Utpatel, K., Evert, M., Hirt, S.W., Geissler, E.K., Fichtner-Feigl, S., Mack, M.: Basophils Trigger Fibroblast Activation in Cardiac Allograft Fibrosis Development. Am. J. Transplant.. 2016.09; 16 (9): 2574-2588. ( PubMed , DOI )

  6. Yamanishi, Y., Karasuyama, H.: Basophils and mast cells in immunity and inflammation. Semin Immunopathol. 2016.09; 38 (5): 535-537. ( PubMed , DOI )

  7. Yamanishi, Y., Karasuyama, H.: Basophil-derived IL-4 plays versatile roles in immunity. Semin Immunopathol. 2016.09; 38 (5): 615-622. ( PubMed , DOI )

  8. Baba, T., Tanabe, Y., Yoshikawa, S., Yamanishi, Y., Morishita, S., Komatsu, N., Karasuyama, H., Hirao, A., Mukaida N.: MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice. Blood. 2016.05; 127 (21): 2607-2617. ( PubMed , DOI )

  9. Yoshikawa, S., Usami, T., Kikuta, J., Ishii, M., Sasano, T., Sugiyama, K., Furukawa, T., Nakasho, E., Takayanagi, H., Tedder, T. F., Karasuyama, H., Miyawaki, A., Adachi, T.: Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset. Sci Rep. 2016.01; 6 18738. ( PubMed , DOI )

  10. Adachi, T., Kakuta, S., Aihara, Y., Kamiya, T., Watanabe, Y., Osakabe, N., Hazato, N., Miyawaki, A., Yoshikawa, S., Usami, T., Karasuyama, H., Kimoto-Nira, H., Hirayama, K., M Tsuji, N.: Visualization of Probiotic-Mediated Ca(2+) Signaling in Intestinal Epithelial Cells In Vivo. Front Immunol. 2016; 7 601. ( PubMed , DOI )

  1. LiHua, L., Yoshikawa, S., Ohta, T., Horiguchi, K., Kawano, Y., Ohtsu, H., Yamanishi, Y., and Karasuyama, H.: Large particulate allergens can elicit mast cell-mediated anaphylaxis without exit from blood vessels as efficiently as do small soluble allergens. Biochem. Biophys. Res. Commun. . 2015.11; 467 (6 (1)): 70-75. ( PubMed )

  2. Morita, H., Arae, K., Unno, H., Nambu, A, Oboki, K., Ohno, T., Matsuda, A., Toyama, S., Miyauchi, K., Yamaguchi, S., Narushima, S., Kajiwara, N., Iikura, M., Suto, H., McKenzie, A., Takahashi, T., Karasuyama, H., Okumara, K., Azuma, M., Galli, SJ., Moro, K., Akdis, C., Koyasu, S., Kubo, M., Sudo, K., Saito, H., Matsumoto, K., and Nakae, S.: An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers. Immunity. 2015.07; 43 (1): 175-186. ( PubMed , DOI )

  3. Tsai, S.H., Kinoshita, M., Kusu, T., Kayama, H., Okumura, R., Ikeda, K., Shimada Y., Takeda A., Yoshikawa, S., Obata-Ninomiya, K., Kurashima, Y., Sato, S., Umemoto, E., Kiyono, H., Karasuyama, H., and Takeda, K.: The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells. Immunity. 2015.02; 42 (2): 279-293. ( PubMed , DOI )

  1. Hajime Karasuyama, Yoshinori Yamanishi: Basophils have emerged as a key player in immunity. Curr. Opin. Immunol.. 2014.12; 31 1-7. ( PubMed , DOI )

  2. Laurent L Reber, Thomas Marichal, Jeremy Sokolove, Philipp Starkl, Nicolas Gaudenzio, Yoichiro Iwakura, Hajime Karasuyama, Lawrence B Schwartz, William H Robinson, Mindy Tsai, Stephen J Galli: Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice. Arthritis and Rheumatology (Hoboken, N.J.). 2014.10; 66 (10): 2881-2891. ( PubMed , DOI )

  3. Mahbubul Morshed, Ruslan Hlushchuk, Dagmar Simon, Andrew F Walls, Kazushige Obata-Ninomiya, Hajime Karasuyama, Valentin Djonov, Alexander Eggel, Thomas Kaufmann, Hans-Uwe Simon, Shida Yousefi: NADPH oxidase-independent formation of extracellular DNA traps by basophils. J. Immunol.. 2014.06; 192 (11): 5314-5323. ( PubMed , DOI )

  4. Nadja Bakocevic, Carla Claser, Soichiro Yoshikawa, Leigh Ann Jones, Samantha Chew, Chi Ching Goh, Benoit Malleret, Anis Larbi, Florent Ginhoux, Maria Curotto de Lafaille, Hajime Karasuyama, Laurent Renia, Lai Guan Ng: CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections. Eur. J. Immunol.. 2014.06; 44 (6): 1823-1834. ( PubMed , DOI )

  5. Egawa, M., Mukai, K., and Karasuyama, H.: Basophil-derived IL-4 induces the differentiation of inflammatory monocytes into M2-type macrophages to dampen allergic inflammation. Allergic diseases: from mechanisms to cures.. 2014; 59-62.

  6. Karasuyama H.: Basophils. Global Atlas of Allergy. 2014; 56-57.

  1. Electron Crystallography of Euglenoid Four-Transmembrane Protein Revealed the Linear Polymerization by a Combination of Three-Ways of Intermolecular Interaction 2013.01; 104 (2): 42A.

  2. Shiraishi Y, Jia Y, Domenico J, Joetham A, Karasuyama H, Takeda K, Gelfand E.W: Sequential engagement of FcεRI on mast cells and basophil histamine H4 receptor and FcεRI in allergic rhinitis Journal of Immunology. 2013.01; 190 (2): 539-548. ( PubMed , DOI )

  3. The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat. 2013; 4 1766. ( PubMed , DOI )

  1. Ogawa H, Mukai K, Kawano Y, Minegishi Y, Karasuyama H: Th2-inducing cytokines IL-4 and IL-33 synergistically elicit the expression of transmembrane TNF-α on macrophages through the autocrine action of IL-6. Biochemical and biophysical research communications. 2012.03; 420 (1): 114-118. ( PubMed , DOI )

  1. Ishikawa Y, Kobayashi K, Yamamoto M, Nakata K, Takagawa T, Funada Y, Kotani Y, Karasuyama H, Yoshida M, Nishimura Y: Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells. Respiratory research. 2011.04; 12 42. ( PubMed , DOI )

  1. Structure and inhibitor of water channel in brain 2010.11; 179-204. ( DOI )

  2. Hara-Chikuma M., Chikuma S., Kabashima K., Nakahigashi K., Kamegawa A., Fujiyoshi Y., Verkman A. S., Sugiyama Y., Inoue S., Miyachi Y.: A controlled aquaporin-3 expression in T lymphocytes regulate their migration and trafficking in cutaneous immune reaction JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010.04; 130 S116.

  1. Takai T, Karasuyama H: The study of allergy by Japanese researchers: a historical perspective. Int Immunol. 2009.12; 21 (12): 1311-1316. ( PubMed , DOI )

  2. Ugajin T, Kojima T, Mukai K, Obata K, Kawano Y, Minegishi Y, Eishi Y, Yokozeki H, Karasuyama H: Basophils preferentially express mouse mast cell protease 11 among the mast cell tryptase family in contrast to mast cells. J Leukoc Biol. 2009.08; ( PubMed , DOI )

  3. Minegishi Y, Saito M, Nagasawa M, Takada H, Hara T, Tsuchiya S, Agematsu K, Yamada M, Kawamura N, Ariga T, Tsuge I, Karasuyama H: Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome. J Exp Med. 2009.06; 206 (6): 1291-1301. ( PubMed , DOI )

  4. Karasuyama H: [An exciting new era of basophil research: newly discovered roles for basophils in acute and chronic allergic reactions] Arerugi. 2009.06; 58 (6): 635-637. ( PubMed )

  5. Mukai K, Obata K, Tsujimura Y, Karasuyama H: New insights into the roles for basophils in acute and chronic allergy. Allergol Int. 2009.03; 58 (1): 11-19. ( PubMed , DOI )

  6. Belkina NV, Liu Y, Hao JJ, Karasuyama H, Shaw S: LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Proc Natl Acad Sci U S A. 2009.03; 106 (12): 4707-4712. ( PubMed , DOI )

  7. Minegishi Y, Karasuyama H: Defects in Jak-STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency. Int Immunol. 2009.02; 21 (2): 105-112. ( PubMed , DOI )

  8. Hida S, Yamasaki S, Sakamoto Y, Takamoto M, Obata K, Takai T, Karasuyama H, Sugane K, Saito T, Taki S: Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol. 2009.02; 10 (2): 214-222. ( PubMed , DOI )

  9. Khodoun M, Strait R, Orekov T, Hogan S, Karasuyama H, Herbert DR, Kohl J, Finkelman FD: Peanuts can contribute to anaphylactic shock by activating complement. J Allergy Clin Immunol. 2009.02; 123 (2): 342-351. ( PubMed , DOI )

  10. Karasuyama H, Mukai K, Tsujimura Y, Obata K: Newly discovered roles for basophils: a neglected minority gains new respect. Nat Rev Immunol. 2009.01; 9 (1): 9-13. ( PubMed , DOI )

  11. Yoshikawa S, Kawano Y, Minegishi Y, Karasuyama H: The skewed heavy-chain repertoire in peritoneal B-1 cells is predetermined by the selection via pre-B cell receptor during B cell ontogeny in the fetal liver. Int Immunol. 2009.01; 21 (1): 43-52. ( PubMed , DOI )

  1. Takada T, Shitara H, Matsuoka K, Kojima E, Ishii R, Kikkawa Y, Taya C, Karasuyama H, Kohno K, Yonekawa H: A novel hairless mouse model on an atopic dermatitis-prone genetic background generated by receptor-mediated transgenesis. Transgenic Res. 2008.12; 17 (6): 1155-1162. ( PubMed , DOI )

  2. Watanabe M, Satoh T, Yamamoto Y, Kanai Y, Karasuyama H, Yokozeki H: Overproduction of IgE induces macrophage-derived chemokine (CCL22) secretion from basophils. J Immunol. 2008.10; 181 (8): 5653-5659. ( PubMed )

  3. Minegishi Y, Karasuyama H: Genetic origins of hyper-IgE syndrome. Curr Allergy Asthma Rep. 2008.09; 8 (5): 386-391. ( PubMed )

  4. Tsujimura Y, Obata K, Mukai K, Shindou H, Yoshida M, Nishikado H, Kawano Y, Minegishi Y, Shimizu T, Karasuyama H: Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity. 2008.04; 28 (4): 581-589. ( PubMed , DOI )

  5. Yasuda T, Sanjo H, Pages G, Kawano Y, Karasuyama H, Pouyssegur J, Ogata M, Kurosaki T: Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion. Immunity. 2008.04; 28 (4): 499-508. ( PubMed , DOI )

  6. Assembly of Aquaporin-4 into square arrays is restricted by palmitoylation of N-terminal cysteine residues 2008; 61 S148.

  1. Minegishi Y, Karasuyama H: Hyperimmunoglobulin E syndrome and tyrosine kinase 2 deficiency. Curr Opin Allergy Clin Immunol. 2007.12; 7 (6): 506-509. ( PubMed , DOI )

  2. Kojima T, Obata K, Mukai K, Sato S, Takai T, Minegishi Y, Karasuyama H: Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner. J Immunol. 2007.11; 179 (10): 7093-7100. ( PubMed )

  3. Obata K, Mukai K, Tsujimura Y, Ishiwata K, Kawano Y, Minegishi Y, Watanabe N, Karasuyama H: Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood. 2007.08; 110 (3): 913-920. ( PubMed , DOI )

  4. Minegishi Y, Saito M, Tsuchiya S, Tsuge I, Takada H, Hara T, Kawamura N, Ariga T, Pasic S, Stojkovic O, Metin A, Karasuyama H: Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature. 2007.08; 448 (7157): 1058-1062. ( PubMed , DOI )

  5. Yakata Kaya, Hiroaki Yoko, Ishibashi Kenichi, Sohara Eisei, Sasaki Sei, Mitsuoka Kaoru, Fujiyoshi Yoshinori: Aquaporin-11 containing a divergent NPA motif has normal water channel activity. Biochim Biophys Acta. 2007.03; 1768 (3): 688-693. ( PubMed , DOI )

  1. Ochiai K, Katoh Y, Ikura T, Hoshikawa Y, Noda T, Karasuyama H, Tashiro S, Muto A, Igarashi K: Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells. J Biol Chem. 2006.12; 281 (50): 38226-38234. ( PubMed , DOI )

  2. Minegishi Y, Saito M, Morio T, Watanabe K, Agematsu K, Tsuchiya S, Takada H, Hara T, Kawamura N, Ariga T, Kaneko H, Kondo N, Tsuge I, Yachie A, Sakiyama Y, Iwata T, Bessho F, Ohishi T, Joh K, Imai K, Kogawa K, Shinohara M, Fujieda M, Wakiguchi H, Pasic S, Abinun M, Ochs HD, Renner ED, Jansson A, Belohradsky BH, Metin A, Shimizu N, Mizutani S, Miyawaki T, Nonoyama S, Karasuyama H: Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity. 2006.11; 25 (5): 745-755. ( PubMed , DOI )

  3. Yamamoto M, Hayashi K, Nojima T, Matsuzaki Y, Kawano Y, Karasuyama H, Goitsuka R, Kitamura D: BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces kappa gene rearrangement. Blood. 2006.10; 108 (8): 2703-2711. ( PubMed , DOI )

  4. Kawano Y, Yoshikawa S, Minegishi Y, Karasuyama H: Pre-B cell receptor assesses the quality of IgH chains and tunes the pre-B cell repertoire by delivering differential signals. J Immunol. 2006.08; 177 (4): 2242-2249. ( PubMed )

  5. Kubota T, Mukai K, Minegishi Y, Karasuyama H: Different stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains. J Immunol. 2006.06; 176 (11): 7008-7014. ( PubMed )

  1. Mukai K, Matsuoka K, Taya C, Suzuki H, Yokozeki H, Nishioka K, Hirokawa K, Etori M, Yamashita M, Kubota T, Minegishi Y, Yonekawa H, Karasuyama H: Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells. Immunity. 2005.08; 23 (2): 191-202. ( PubMed , DOI )

  2. Kawano Y, Yoshikawa S, Minegishi Y, Karasuyama H: Selection of stereotyped VH81X-{micro}H chains via pre-B cell receptor early in ontogeny and their conservation in adults by marginal zone B cells. Int Immunol. 2005.07; 17 (7): 857-867. ( PubMed , DOI )

  3. Jimi E, Phillips RJ, Rincon M, Voll R, Karasuyama H, Flavell R, Ghosh S: Activation of NF-kappaB promotes the transition of large, CD43+ pre-B cells to small, CD43- pre-B cells. Int Immunol. 2005.06; 17 (6): 815-825. ( PubMed , DOI )

  4. Omata N, Ohshima Y, Yasutomi M, Yamada A, Karasuyama H, Mayumi M: Ovalbumin-specific IgE modulates ovalbumin-specific T-cell response after repetitive oral antigen administration. J Allergy Clin Immunol. 2005.04; 115 (4): 822-827. ( PubMed , DOI )

  5. Toyama-Sorimachi N, Omatsu Y, Onoda A, Tsujimura Y, Iyoda T, Kikuchi-Maki A, Sorimachi H, Dohi T, Taki S, Inaba K, Karasuyama H: Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner. J Immunol. 2005.04; 174 (8): 4621-4629. ( PubMed )

  6. Shinohara H, Inoue A, Toyama-Sorimachi N, Nagai Y, Yasuda T, Suzuki H, Horai R, Iwakura Y, Yamamoto T, Karasuyama H, Miyake K, Yamanashi Y: Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling. J Exp Med. 2005.02; 201 (3): 333-339. ( PubMed , DOI )

  1. Taguchi T, Kiyokawa N, Takenouch H, Matsui J, Tang WR, Nakajima H, Suzuki K, Shiozawa Y, Saito M, Katagiri YU, Takahashi T, Karasuyama H, Matsuo Y, Okita H, Fujimoto J: Deficiency of BLNK hampers PLC-gamma2 phosphorylation and Ca2+ influx induced by the pre-B-cell receptor in human pre-B cells. Immunology. 2004.08; 112 (4): 575-582. ( PubMed , DOI )

  2. Kiyokawa N, Sekino T, Matsui T, Takenouchi H, Mimori K, Tang WR, Matsui J, Taguchi T, Katagiri YU, Okita H, Matsuo Y, Karasuyama H, Fujimoto J: Diagnostic importance of CD179a/b as markers of precursor B-cell lymphoblastic lymphoma. Mod Pathol. 2004.04; 17 (4): 423-429. ( PubMed , DOI )

  3. Maezawa Y, Nakajima H, Seto Y, Suto A, Kumano K, Kubo S, Karasuyama H, Saito Y, Iwamoto I: IgE-dependent enhancement of Th2 cell-mediated allergic inflammation in the airways. Clin Exp Immunol. 2004.01; 135 (1): 12-18. ( PubMed )

  4. Toyama-Sorimachi N, Tsujimura Y, Maruya M, Onoda A, Kubota T, Koyasu S, Inaba K, Karasuyama H: Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architecture. Proc Natl Acad Sci U S A. 2004.01; 101 (4): 1016-1021. ( PubMed , DOI )

  1. Minami J, Eishi Y, Ishige Y, Kobayashi I, Ishige I, Kobayashi D, Ando N, Uchida K, Ikeda S, Sorimachi N, Karasuyama H, Takemura T, Takizawa T, Koike M: Pulmonary granulomas caused experimentally in mice by a recombinant trigger-factor protein of Propionibacterium acnes. J Med Dent Sci. 2003.12; 50 (4): 265-274. ( PubMed )

  2. Kawashima I, Yoshida Y, Taya C, Shitara H, Yonekawa H, Karasuyama H, Tada N, Furukawa K, Tai T: Expansion of natural killer cells in mice transgenic for IgM antibody to ganglioside GD2: demonstration of prolonged survival after challenge with syngeneic tumor cells. Int J Oncol. 2003.08; 23 (2): 381-388. ( PubMed )

  3. Terauchi M, Koi H, Hayano C, Toyama-Sorimachi N, Karasuyama H, Yamanashi Y, Aso T, Shirakata M: Placental extravillous cytotrophoblasts persistently express class I major histocompatibility complex molecules after human cytomegalovirus infection. J Virol. 2003.08; 77 (15): 8187-8195. ( PubMed )

  4. Maezawa Y, Nakajima H, Kumano K, Kubo S, Karasuyama H, Iwamoto I: Role of IgE in Th2 cell-mediated allergic airway inflammation. Int Arch Allergy Immunol. 2003.06; 131 Suppl 1 2-6. ( PubMed , DOI )

  5. Saijo K, Schmedt C, Su IH, Karasuyama H, Lowell CA, Reth M, Adachi T, Patke A, Santana A, Tarakhovsky A: Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nat Immunol. 2003.03; 4 (3): 274-279. ( PubMed , DOI )

  6. Tsuchiya K, Kawano Y, Kojima T, Nagata K, Takao T, Okada M, Shinohara H, Maki K, Toyama-Sorimachi N, Miyasaka N, Watanabe M, Karasuyama H: Molecular cloning and characterization of TPP36 and its isoform TPP32, novel substrates of Abl tyrosine kinase. FEBS Lett. 2003.02; 537 (1-3): 203-209. ( PubMed )

  7. Sato E, Hirahara K, Wada Y, Yoshitomi T, Azuma T, Matsuoka K, Kubo S, Taya C, Yonekawa H, Karasuyama H, Shiraishi A: Chronic inflammation of the skin can be induced in IgE transgenic mice by means of a single challenge of multivalent antigen. J Allergy Clin Immunol. 2003.01; 111 (1): 143-148. ( PubMed )

  8. Kubo S, Nakayama T, Matsuoka K, Yonekawa H, Karasuyama H: Long term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE. J Immunol. 2003.01; 170 (2): 775-780. ( PubMed )

  9. Taguchi T, Kiyokawa N, Mimori K, Suzuki T, Sekino T, Nakajima H, Saito M, Katagiri YU, Matsuo N, Matsuo Y, Karasuyama H, Fujimoto J: Pre-B cell antigen receptor-mediated signal inhibits CD24-induced apoptosis in human pre-B cells. J Immunol. 2003.01; 170 (1): 252-260. ( PubMed )

  1. Wang YH, Stephan RP, Scheffold A, Kunkel D, Karasuyama H, Radbruch A, Cooper MD: Differential surrogate light chain expression governs B-cell differentiation. Blood. 2002.04; 99 (7): 2459-2467. ( PubMed )

  1. Stephan RP, Elgavish E, Karasuyama H, Kubagawa H, Cooper MD: Analysis of VpreB expression during B lineage differentiation in lambda5-deficient mice. J Immunol. 2001.10; 167 (7): 3734-3739. ( PubMed )

  2. Kinoshita T, Nagata K, Sorimachi N, Karasuyama H, Sekiguchi T, Miyajima A: Oncostatin M suppresses generation of lymphoid progenitors in fetal liver by inhibiting the hepatic microenvironment. Exp Hematol. 2001.09; 29 (9): 1091-1097. ( PubMed )

  3. Kubo S, Matsuoka K, Taya C, Kitamura F, Takai T, Yonekawa H, Karasuyama H: Drastic up-regulation of Fcepsilonri on mast cells is induced by IgE binding through stabilization and accumulation of Fcepsilonri on the cell surface. J Immunol. 2001.09; 167 (6): 3427-3434. ( PubMed )

  4. Agematsu K, Nagumo H, Hokibara S, Mori T, Wada T, Yachie A, Kanegane H, Miyawaki T, Sugita K, Karasuyama H, Komiyama A: Complete arrest from pro- to pre-B cells in a case of B cell-negative severe combined immunodeficiency (SCID) without recombinase activating gene (RAG) mutations. Clin Exp Immunol. 2001.06; 124 (3): 461-464. ( PubMed )

  5. Kouro T, Nagata K, Takaki S, Nisitani S, Hirano M, Wahl MI, Witte ON, Karasuyama H, Takatsu K: Bruton's tyrosine kinase is required for signaling the CD79b-mediated pro-B to pre-B cell transition. Int Immunol. 2001.04; 13 (4): 485-493. ( PubMed )

  6. Toyama-Sorimachi N, Taguchi Y, Yagita H, Kitamura F, Kawasaki A, Koyasu S, Karasuyama H: Mouse CD94 participates in Qa-1-mediated self recognition by NK cells and delivers inhibitory signals independent of Ly-49. J Immunol. 2001.03; 166 (6): 3771-3779. ( PubMed )

  7. Kohara Y, Tanabe K, Matsuoka K, Kanda N, Matsuda H, Karasuyama H, Yonekawa H: A major determinant quantitative-trait locus responsible for atopic dermatitis-like skin lesions in NC/Nga mice is located on Chromosome 9. Immunogenetics. 2001.02; 53 (1): 15-21. ( PubMed )

  8. Shuichi Kubo, Kunie Matsuoka, Choji Taya, Fujiko Kitmura, Hiromichi Yonekawa, Hajime Karasuyama: IgE stabilizes its high affinity receptor (FcεRI) on mast cells in vitro and ex vivo Activating and inhibitory immunoglobulin-like receptors. 2001; 183-188.

  1. Ohnishi K, Shimizu T, Karasuyama H, Melchers F: The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain. J Biol Chem. 2000.10; 275 (40): 31134-31144. ( PubMed , DOI )

  2. Nomura K, Kanegane H, Karasuyama H, Tsukada S, Agematsu K, Murakami G, Sakazume S, Sako M, Tanaka R, Kuniya Y, Komeno T, Ishihara S, Hayashi K, Kishimoto T, Miyawaki T: Genetic defect in human X-linked agammaglobulinemia impedes a maturational evolution of pro-B cells into a later stage of pre-B cells in the B-cell differentiation pathway. Blood. 2000.07; 96 (2): 610-617. ( PubMed )

  3. Nagaoka H, Takahashi Y, Hayashi R, Nakamura T, Ishii K, Matsuda J, Ogura A, Shirakata Y, Karasuyama H, Sudo T, Nishikawa S, Tsubata T, Mizuochi T, Asano T, Sakano H, Takemori T: Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage. J Exp Med. 2000.07; 192 (2): 171-182. ( PubMed )

  4. Ellinger-Ziegelbauer H, Karasuyama H, Yamada E, Tsujikawa K, Todokoro K, Nishida E: Ste20-like kinase (SLK), a regulatory kinase for polo-like kinase (Plk) during the G2/M transition in somatic cells. Genes Cells. 2000.06; 5 (6): 491-498. ( PubMed )

  5. Donohoe ME, Beck-Engeser GB, Lonberg N, Karasuyama H, Riley RL, Jack HM, Blomberg BB: Transgenic human lambda 5 rescues the murine lambda 5 nullizygous phenotype. J Immunol. 2000.05; 164 (10): 5269-5276. ( PubMed )

  6. Tagawa K, Taya C, Hayashi Y, Nakagawa M, Ono Y, Fukuda R, Karasuyama H, Toyama-Sorimachi N, Katsui Y, Hata S, Ishiura S, Nonaka I, Seyama Y, Arahata K, Yonekawa H, Sorimachi H, Suzuki K: Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A. Hum Mol Genet. 2000.05; 9 (9): 1393-1402. ( PubMed )

  7. Maki K, Nagata K, Kitamura F, Takemori T, Karasuyama H: Immunoglobulin beta signaling regulates locus accessibility for ordered immunoglobulin gene rearrangements. J Exp Med. 2000.04; 191 (8): 1333-1340. ( PubMed )

  8. Endo J, Toyama-Sorimachi N, Taya C, Kuramochi-Miyagawa S, Nagata K, Kuida K, Takashi T, Yonekawa H, Yoshizawa Y, Miyasaka N, Karasuyama H: Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes. FEBS Lett. 2000.02; 468 (2-3): 234-238. ( PubMed )

  1. Bosma GC, Chang Y, Karasuyama H, Bosma MJ: Differential effect of an Ig mu transgene on development of pre-B cells in fetal and adult SCID mice. Proc Natl Acad Sci U S A. 1999.10; 96 (21): 11952-11957. ( PubMed )

  2. Miyazaki T, Kato I, Takeshita S, Karasuyama H, Kudo A: Lambda5 is required for rearrangement of the Ig kappa light chain gene in pro-B cell lines. Int Immunol. 1999.08; 11 (8): 1195-1202. ( PubMed )

  3. Matsuoka K, Taya C, Kubo S, Toyama-Sorimachi N, Kitamura F, Ra C, Yonekawa H, Karasuyama H: Establishment of antigen-specific IgE transgenic mice to study pathological and immunobiological roles of IgE in vivo. Int Immunol. 1999.06; 11 (6): 987-994. ( PubMed )

  4. Kuramochi S, Matsuda Y, Okamoto M, Kitamura F, Yonekawa H, Karasuyama H: Molecular cloning of the human gene STK10 encoding lymphocyte-oriented kinase, and comparative chromosomal mapping of the human, mouse, and rat homologues. Immunogenetics. 1999.05; 49 (5): 369-375. ( PubMed )

  1. Tsuganezawa K, Kiyokawa N, Matsuo Y, Kitamura F, Toyama-Sorimachi N, Kuida K, Fujimoto J, Karasuyama H: Flow cytometric diagnosis of the cell lineage and developmental stage of acute lymphoblastic leukemia by novel monoclonal antibodies specific to human pre-B-cell receptor. Blood. 1998.12; 92 (11): 4317-4324. ( PubMed )

  2. Muto A, Hoshino H, Madisen L, Yanai N, Obinata M, Karasuyama H, Hayashi N, Nakauchi H, Yamamoto M, Groudine M, Igarashi K: Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer. EMBO J. 1998.10; 17 (19): 5734-5743. ( PubMed , DOI )

  3. Meffre E, Papavasiliou F, Cohen P, de Bouteiller O, Bell D, Karasuyama H, Schiff C, Banchereau J, Liu YJ, Nussenzweig MC: Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells. J Exp Med. 1998.08; 188 (4): 765-772. ( PubMed )

  4. Kuida K, Haydar TF, Kuan CY, Gu Y, Taya C, Karasuyama H, Su MS, Rakic P, Flavell RA: Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell. 1998.08; 94 (3): 325-337. ( PubMed )

  1. Koyama M, Ishihara K, Karasuyama H, Cordell JL, Iwamoto A, Nakamura T: CD79 alpha/CD79 beta heterodimers are expressed on pro-B cell surfaces without associated mu heavy chain. Int Immunol. 1997.11; 9 (11): 1767-1772. ( PubMed )

  2. Nagata K, Nakamura T, Kitamura F, Kuramochi S, Taki S, Campbell KS, Karasuyama H: The Ig alpha/Igbeta heterodimer on mu-negative proB cells is competent for transducing signals to induce early B cell differentiation. Immunity. 1997.10; 7 (4): 559-570. ( PubMed )

  3. Kuramochi S, Moriguchi T, Kuida K, Endo J, Semba K, Nishida E, Karasuyama H: LOK is a novel mouse STE20-like protein kinase that is expressed predominantly in lymphocytes. J Biol Chem. 1997.09; 272 (36): 22679-22684. ( PubMed )

  4. Emoto K, Toyama-Sorimachi N, Karasuyama H, Inoue K, Umeda M: Exposure of phosphatidylethanolamine on the surface of apoptotic cells. Exp Cell Res. 1997.05; 232 (2): 430-434. ( PubMed , DOI )

  5. Karasuyama H, Nakamura T, Nagata K, Kuramochi T, Kitamura F, Kuida K: The roles of preB cell receptor in early B cell development and its signal transduction. Immunol Cell Biol. 1997.04; 75 (2): 209-216. ( PubMed , DOI )

  1. Kuida K, Zheng TS, Na S, Kuan C, Yang D, Karasuyama H, Rakic P, Flavell RA: Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature. 1996.11; 384 (6607): 368-372. ( PubMed , DOI )

  2. Maki K, Sunaga S, Komagata Y, Kodaira Y, Mabuchi A, Karasuyama H, Yokomuro K, Miyazaki JI, Ikuta K: Interleukin 7 receptor-deficient mice lack gammadelta T cells. Proc Natl Acad Sci U S A. 1996.07; 93 (14): 7172-7177. ( PubMed )

  3. Karasuyama H, Rolink A, Melchers F: Surrogate light chain in B cell development. Adv Immunol. 1996; 63 1-41. ( PubMed )

  1. Sawai H, Yamasaki N, Shigeta M, Komori S, Karasuyama H, Koyama K, Isojima S: Direct production of the Fab fragment derived from the sperm immobilizing antibody using polymerase chain reaction and cDNA expression vectors. Am J Reprod Immunol. 1995.07; 34 (1): 26-34. ( PubMed )

  2. Rolink A, Ghia P, Grawunder U, Haasner D, Karasuyama H, Kalberer C, Winkler T, Melchers F: In-vitro analyses of mechanisms of B-cell development. Semin Immunol. 1995.06; 7 (3): 155-167. ( PubMed )

  3. Melchers F, Rolink A, Grawunder U, Winkler TH, Karasuyama H, Ghia P, Andersson J: Positive and negative selection events during B lymphopoiesis. Curr Opin Immunol. 1995.04; 7 (2): 214-227. ( PubMed )

  4. Winkler TH, Rolink A, Melchers F, Karasuyama H: Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface. Eur J Immunol. 1995.02; 25 (2): 446-450. ( PubMed )

  1. Rolink A, Grawunder U, Winkler TH, Karasuyama H, Melchers F: IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development. Int Immunol. 1994.08; 6 (8): 1257-1264. ( PubMed )

  2. Karasuyama H, Rolink A, Shinkai Y, Young F, Alt FW, Melchers F: The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice. Cell. 1994.04; 77 (1): 133-143. ( PubMed )

  3. Rolink A, Karasuyama H, Haasner D, Grawunder U, Martensson IL, Kudo A, Melchers F: Two pathways of B-lymphocyte development in mouse bone marrow and the roles of surrogate L chain in this development. Immunol Rev. 1994.02; 137 185-201. ( PubMed )

  4. Melchers F, Haasner D, Grawunder U, Kalberer C, Karasuyama H, Winkler T, Rolink AG: Roles of IgH and L chains and of surrogate H and L chains in the development of cells of the B lymphocyte lineage. Annu Rev Immunol. 1994; 12 209-225. ( PubMed , DOI )

  1. Karasuyama H, Rolink A, Melchers F: A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines. J Exp Med. 1993.08; 178 (2): 469-478. ( PubMed )

  2. Rolink A, Karasuyama H, Grawunder U, Haasner D, Kudo A, Melchers F: B cell development in mice with a defective lambda 5 gene. Eur J Immunol. 1993.06; 23 (6): 1284-1288. ( PubMed )

  3. Sawai H, Yamasaki N, Komori S, Karasuyama H, Isojima S: Stable production of recombinant human sperm immobilizing antibody using cDNA expression vectors. Am J Reprod Immunol. 1993.03; 29 (2): 100-108. ( PubMed )

  4. Melchers F, Karasuyama H, Haasner D, Bauer S, Kudo A, Sakaguchi N, Jameson B, Rolink A: The surrogate light chain in B-cell development. Immunol Today. 1993.02; 14 (2): 60-68. ( PubMed )

  1. Uemura N, Ozawa K, Tojo A, Takahashi K, Okano A, Karasuyama H, Tani K, Asano S: Acquisition of interleukin-3 independence in FDC-P2 cells after transfection with the activated c-H-ras gene using a bovine papillomavirus-based plasmid vector. Blood. 1992.12; 80 (12): 3198-3204. ( PubMed )

  2. Melchers F, Haasner D, Karasuyama H, Reininger L, Rolink A: Progenitor and precursor B lymphocytes of mice. Proliferation and differentiation in vitro and population, differentiation and turnover in SCID mice in vivo of normal and abnormal cells. Curr Top Microbiol Immunol. 1992; 182 3-12. ( PubMed )

  1. Golumbek PT, Lazenby AJ, Levitsky HI, Jaffee LM, Karasuyama H, Baker M, Pardoll DM: Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science. 1991.11; 254 (5032): 713-716. ( PubMed )

  2. Yamamura Y, Kotani M, Chowdhury MI, Yamamoto N, Yamaguchi K, Karasuyama H, Katsura Y, Miyasaka M: Infection of human CD4+ rabbit cells with HIV-1: the possibility of the rabbit as a model for HIV-1 infection. Int Immunol. 1991.11; 3 (11): 1183-1187. ( PubMed )

  3. Tanaka T, Tsudo M, Karasuyama H, Kitamura F, Kono T, Hatakeyama M, Taniguchi T, Miyasaka M: A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells. J Immunol. 1991.10; 147 (7): 2222-2228. ( PubMed )

  4. Rolink A, Kudo A, Karasuyama H, Kikuchi Y, Melchers F: Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo. EMBO J. 1991.02; 10 (2): 327-336. ( PubMed )

  5. Tanaka T, Tsudo M, Karasuyama H, Toyama N, Hatakeyama M, Taniguchi T, Miyasaka M: Signal transduction through the human IL-2 receptor beta-chain expressed in IL-6-dependent mouse B cell hybridoma. Int Immunol. 1991.01; 3 (1): 105-108. ( PubMed )

  6. Miyajima H, Hirano T, Hirose S, Karasuyama H, Okumura K, Ovary Z: Suppression by IL-2 of IgE production by B cells stimulated by IL-4. J Immunol. 1991.01; 146 (2): 457-462. ( PubMed )

  1. Yamamura Y, Kotani M, Tsudo M, Karasuyama H, Seto A, Miyasaka M: IL-2 receptors on rabbit T-cell lines and their transfectants expressing the human IL-2 receptor alpha chain. Immunology. 1990.12; 71 (4): 502-507. ( PubMed )

  2. Karasuyama H, Kudo A, Melchers F: The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain. J Exp Med. 1990.09; 172 (3): 969-972. ( PubMed )

  3. Tsudo M, Karasuyama H, Kitamura F, Tanaka T, Kubo S, Yamamura Y, Tamatani T, Hatakeyama M, Taniguchi T, Miyasaka M: The IL-2 receptor beta-chain (p70). Ligand binding ability of the cDNA-encoding membrane and secreted forms. J Immunol. 1990.07; 145 (2): 599-606. ( PubMed )

  4. Tohyama N, Karasuyama H, Tada T: Growth autonomy and tumorigenicity of interleukin 6-dependent B cells transfected with interleukin 6 cDNA. J Exp Med. 1990.02; 171 (2): 389-400. ( PubMed )

  5. Fearon ER, Pardoll DM, Itaya T, Golumbek P, Levitsky HI, Simons JW, Karasuyama H, Vogelstein B, Frost P: Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell. 1990.02; 60 (3): 397-403. ( PubMed )

  6. Sano K, Kishimoto H, Karasuyama H, Asano Y, Tada T: Cell division-associated expression of an epitope, KH17, on early developing thymocytes. Int Immunol. 1990; 2 (8): 725-733. ( PubMed )

  1. Tsudo M, Karasuyama H, Kitamura F, Nagasaka Y, Tanaka T, Miyasaka M: Reconstitution of a functional IL-2 receptor by the beta-chain cDNA. A newly acquired receptor transduces negative signal. J Immunol. 1989.12; 143 (12): 4039-4043. ( PubMed )

  2. Sato T, Kohno S, Kobayashi H, Yoshida K, Karasuyama H, Tabata T: [Prosthetic application of a new measuring instrument of the dynamic periodontal function] Nihon Hotetsu Shika Gakkai Zasshi. 1989.10; 33 (5): 1202-1211. ( PubMed )

  3. Tani K, Ozawa K, Ogura H, Takahashi T, Okano A, Watari K, Matsudaira T, Tajika K, Karasuyama H, Nagata S, et al.: Implantation of fibroblasts transfected with human granulocyte colony-stimulating factor cDNA into mice as a model of cytokine-supplement gene therapy. Blood. 1989.09; 74 (4): 1274-1280. ( PubMed )

  4. Tonouchi N, Miwa K, Karasuyama H, Matsui H: Deletion of 3' untranslated region of human BSF-2 mRNA causes stabilization of the mRNA and high-level expression in mouse NIH3T3 cells. Biochem Biophys Res Commun. 1989.09; 163 (2): 1056-1062. ( PubMed )

  5. Karasuyama H, Tohyama N, Tada T: Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene. J Exp Med. 1989.01; 169 (1): 13-25. ( PubMed )

  6. Yagita H, Nakamura T, Karasuyama H, Okumura K: Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. Proc Natl Acad Sci U S A. 1989.01; 86 (2): 645-649. ( PubMed )

  7. Melchers F, Bauer SR, Berger C, Karasuyama H, Kudo A, Rolink A, Sakaguchi N, Strasser A, Thalmann P: Precursor B lymphocytes--specific monoclonal antibodies and genes. Adv Exp Med Biol. 1989; 254 87-93. ( PubMed )

  1. Karasuyama H: [Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using high-copy cDNA expression vectors] Tanpakushitsu Kakusan Koso. 1988.11; 33 (14): 2527-2532. ( PubMed )

  2. Kohno S, Karasuyama H, Yoshida K, Kobayashi H: [A study on the causative mechanism of occlusal interference on the balancing side] Nihon Hotetsu Shika Gakkai Zasshi. 1988.04; 32 (2): 505-513. ( PubMed )

  3. Karasuyama H, Rolink A, Melchers F: Recombinant interleukin 2 or 5, but not 3 or 4, induces maturation of resting mouse B lymphocytes and propagates proliferation of activated B cell blasts. J Exp Med. 1988.04; 167 (4): 1377-1390. ( PubMed )

  4. Karasuyama H, Melchers F: Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur J Immunol. 1988.01; 18 (1): 97-104. ( PubMed )

  5. Asano Y, Nakayama T, Kubo M, Fujisawa I, Karasuyama H, Singer A, Hodes RJ, Tada T: Analysis of two distinct B cell activation pathways mediated by a monoclonal T helper cell. II. T helper cell secretion of interleukin 4 selectively inhibits antigen-specific B cell activation by cognate, but not noncognate, interactions with T cells. J Immunol. 1988.01; 140 (2): 419-426. ( PubMed )

  1. Palacios R, Karasuyama H, Rolink A: Ly1+ PRO-B lymphocyte clones. Phenotype, growth requirements and differentiation in vitro and in vivo. EMBO J. 1987.12; 6 (12): 3687-3693. ( PubMed )

  2. Staerz UD, Karasuyama H, Garner AM: Cytotoxic T lymphocytes against a soluble protein. Nature. 1987.10; 329 (6138): 449-451. ( PubMed , DOI )

  3. Lernhardt W, Karasuyama H, Rolink A, Melchers F: Control of the cell cycle of murine B lymphocytes: the nature of alpha- and beta-B-cell growth factors and of B-cell maturation factors. Immunol Rev. 1987.10; 99 241-262. ( PubMed )

  1. Karasuyama H, Kim M, Okumura K, Tada T: Heterogeneity of Igh-linked allotypic determinants expressed on functional T cell subsets as detected by monoclonal antibodies. Eur J Immunol. 1984.05; 14 (5): 413-420. ( PubMed )

  2. Abe R, Karasuyama H, Yagi J, Tada T: Regulation of allotype-linked NPb idiotype by an idiotype-positive soluble factor derived from a T cell hybridoma. Coupling of the circuit regulation to the network concept. Int Arch Allergy Appl Immunol. 1984; 74 (4): 289-296. ( PubMed )

  1. Tada T, Okumura K, Yamada S, Kitahara T, Karasuyama H, Ochi A, Yamauchi K: Regulation of tumor-specific immune response by T cell products. Prog Clin Biol Res. 1983; 132B 345-351. ( PubMed )

  2. Tada T, Okumura K, Miyatani S, Ochi A, Nakauchi H, Karasuyama H: Restricting elements in the immunological circuitry: the role of I region-controlled determinants. Ann N Y Acad Sci. 1983; 418 189-197. ( PubMed )

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  3. 烏山 一: アレルギー疾患 アトピー性皮膚炎病態形成における好塩基球由来IL-4の役割 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 63.

  4. 藤吉 好則: クライオ電子顕微鏡が激変させたタンパク質の立体構造解析技術 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 84. ( 医中誌 )

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  6. 中西 華代, 入江 克雅, 瀬川 勝盛, 長田 重一, 長谷川 和也, 藤吉 好則, 阿部 一啓: ヒト細胞膜フリッパーゼATP11CのX線結晶構造解析 日本生化学会大会プログラム・講演要旨集. 2020.09; 93回 [P-132]. ( 医中誌 )

  7. 柴田 翔, 山本 周平, 杉原 潤, 土井 将史, 井上 信一郎, 三宅 健介, 立石 知也, 山西 吉典, 烏山 一, 宮崎 泰成: エラスターゼ誘導肺気腫モデルにおいて、IL-3が重要な役割を果たしている 日本呼吸器学会誌. 2020.08; 9 (増刊): 190. ( 医中誌 )

  8. 柴田 翔, 烏山 一: 【呼吸器病学TOPICS 2019-20】閉塞性肺疾患　COPD発症における好塩基球の役割 分子呼吸器病. 2020.03; 24 (1): 20-22. ( 医中誌 )

  9. 三宅 健介, 吉川 宗一郎, 柴田 翔, 山西 吉典, 烏山 一: 【アレルギーのエフェクター細胞研究の進展】好塩基球 臨床免疫・アレルギー科. 2020.01; 73 (1): 6-13. ( 医中誌 )

  10. Karasuyama H: [PREVIOUSLY-UNAPPRECIATED ROLES FOR BASOPHILS IN HEALTH AND DISEASE]. Arerugi = [Allergy]. 2020; 69 (10): 964-967. ( PubMed , DOI )

  1. 柴田　翔, 烏山　一: 呼吸器内科学　慢性閉塞性肺疾患（COPD)の病態における好塩基球の役割 医学のあゆみ. 2019.07; 270 (4): 356-357.

  2. 柴田 翔, 烏山 一: 呼吸器内科学　慢性閉塞性肺疾患(COPD)の病態における好塩基球の役割 医学のあゆみ. 2019.07; 270 (4): 356-357. ( 医中誌 )

  3. 山西　吉典, 烏山　一: 好塩基球によるユニークなアレルギー炎症調節機構 実験医学. 2019.06; 37 (10): 1586-1592.

  4. 山西 吉典, 烏山 一: 【新時代が始まった-アレルギー疾患研究　疾患多様性を理解し病態の層別化に基づく治療を実現する】(第1章)アレルギーのメカニズム研究　免疫細胞とサイトカインなど　好塩基球によるユニークなアレルギー炎症調節機構 実験医学. 2019.06; 37 (10): 1586-1592. ( 医中誌 )

  5. 三宅　健介, 烏山　一 : 好塩基球による、トロゴサイトーシスを介した新たな抗原提示メカニズム 感染・炎症・免疫. 2019.04; 49 (1): 61-64.

  6. 三宅 健介, 烏山 一: 好塩基球による、トロゴサイトーシスを介した新たな抗原提示メカニズム 感染・炎症・免疫. 2019.04; 49 (1): 61-64. ( 医中誌 )

  7. 三宅 健介, 烏山 一: 好塩基球による、トロゴサイトーシスを介した新たな抗原提示メカニズム 感染・炎症・免疫. 2019.04; 49 (1): 61-64.

  8. 三宅 健介, 吉川 宗一郎, 山西 吉典, 烏山 一: Th2型免疫応答における好塩基球の役割 臨床免疫・アレルギー科. 2019.02; 71 (2): 177-184.

  9. 四郎園 巧, 崎山 竜人, 池鯉鮒 麻美, 小島 利之, 烏山 一, 池水 信二: CD200-CD200R複合体の結晶構造解析 SPring-9/SACLA Res. Report. 2019.01; 7 1-4.

  1. 三宅健介, 山西吉典, 烏山　一: トロゴサイトーシスを介した好塩基球による抗原提示機構 臨床免疫・アレルギー科. 2018.12; 70 (6): 623-630. ( 医中誌 )

  2. 山西　吉典, 烏山　一: 【自然免疫の最前線】自然免疫系による疾患の誘導と制御　好塩基球によるアレルギー炎症の誘導と抑制（解説/特集） 医学のあゆみ. 2018.06; 265 (3): 1257-1262. ( 医中誌 )

  3. 山西 吉典, 烏山 一: 【アレルギー研究最前線】基礎研究の最前線　上皮細胞、炎症細胞など　最近明らかになったアレルギー炎症病態における好塩基球の多彩な役割 医学のあゆみ. 2018.06; 265 (9): 767-772. ( 医中誌 )

  4. 山西 吉典, 烏山 一: 【自然免疫の最前線】自然免疫系による疾患の誘導と制御　好塩基球によるアレルギー炎症の誘導と抑制 医学のあゆみ. 2018.06; 265 (13): 1257-1262. ( 医中誌 )

  5. 山西　吉典, 烏山　一 : 【アレルギー研究最前線】基礎研究の最前線　上皮細胞、炎症細胞など最近明らかになったアレルギー炎症病態における好塩基球の多彩な役割（解説/特集） 医学のあゆみ. 2018.06; 265 (9): 767-772. ( 医中誌 )

  6. 烏山 一: 基礎免疫研究が拓くアレルギー炎症疾患病態の理解と制御 好塩基球の存在意義とアレルギー病態形成における役割 アレルギー. 2018.05; 67 (4-5): 424. ( 医中誌 )

  7. 三宅健介, 烏山一: 好塩基球（解説） 鼻アレルギー フロンティア. 2018.02; 18 (1): 22-23. ( 医中誌 )

  8. 三宅 健介, 烏山 一: 好塩基球 鼻アレルギーフロンティア. 2018.02; 18 (1): 22-23. ( 医中誌 )

  1. Tsutsui Hidemitsu, Yamanishi Yoshinori, Ohtsuka Hiromi, Sato Shingo, Yoshikawa Soichiro, Karasuyama Hajime: Basophil-specific protease mMCP-8 induces cutaneous inflammation accompanied by chemokine-mediated leukocyte infiltration CYTOKINE. 2017.12; 100 134.

  2. 三宅 健介, 烏山 一: 免疫学　Th2分化における好塩基球の役割 医学のあゆみ. 2017.09; 262 (13): 1183-1184. ( 医中誌 )

  3. 烏山　一 : これまで見逃されていた好塩基球の存在意義と病態形成における役割　山椒は小粒でもぴりりと辛い（会議録） 日本臨床免疫学会会誌. 2017.08; 40 (4): 255. ( 医中誌 )

  4. 長尾 峻久, 山西 吉典, 烏山 一: 好塩基球による免疫応答制御 血液内科. 2017.08; 75 (2): 130-136.

  5. 烏山 一: これまで見逃されていた好塩基球の存在意義と病態形成における役割 山椒は小粒でもぴりりと辛い（会議録） 日本臨床免疫学会会誌. 2017.08; 40 (4): 255. ( DOI )

  6. 長尾 峻久, 山西 吉典, 烏山 一: 【好酸球、好塩基球の機能とその異常】好塩基球による免疫応答制御 血液内科. 2017.08; 75 (2): 130-136. ( 医中誌 )

  7. 壹岐美紗子, 山西吉典, 烏山　一: 好塩基球トリプターゼmMCP-11はIgE依存的慢性アレルギー炎症の誘導に重要な役割を果たす 臨床免疫・アレルギー科. 2017.07; 68 (1): 19-24.

  8. 壹岐 美紗子, 山西 吉典, 烏山 一: 【アレルギーとIgE・マスト細胞】好塩基球トリプターゼmMCP-11はIgE依存的慢性アレルギー炎症の誘導に重要な役割を果たす 臨床免疫・アレルギー科. 2017.07; 68 (1): 19-24. ( 医中誌 )

  9. 柴田　翔、立石　知也、吉川　宗一郎、山西　吉典、稲瀬　直彦: 動物モデル　気道炎症　COPDの病態における炎症性単球、間質マクロファージの役割（会議録） アレルギー. 2017.05; 66 (4-5): 606.

  10. 長尾 峻久, 山西 吉典, 烏山 一: 【生体バリア　粘膜や皮膚を舞台とした健康と疾患のダイナミクス】(第1章)生体バリアを支える分子・細胞・組織基盤　免疫・間葉系細胞による生物学的バリア　皮膚バリアにおける好塩基球の重要性 実験医学. 2017.05; 35 (7): 1123-1128. ( 医中誌 )

  11. 柴田 翔, 立石 知也, 吉川 宗一郎, 山西 吉典, 稲瀬 直彦, 烏山 一: 動物モデル 気道炎症 COPDの病態における炎症性単球、間質マクロファージの役割（会議録） アレルギー. 2017.05; 66 (4-5): 606.

  12. 長尾俊久, 山西吉典, 烏山　一: 皮膚バリアにおける好塩基球の重要性 実験医学. 2017.04; 35 (7): 1123-1128.

  13. 三宅健介, 烏山 一: Th2分化における好塩基球の役割 医学のあゆみ. 2017.01; 262 (13): 1183-1184.

  14. 三宅健介, 烏山 一: Th2分化における好塩基球の役割 医学のあゆみ. 2017.01; 262 (13): 1183-1184.

  15. 三宅　健介、烏山　一 : アレルギーにおける好塩基球の役割（解説） 臨床免疫・アレルギー科. 2017.01; 67 (1): 74-81.

  16. 三宅 健介, 烏山 一: アレルギーにおける好塩基球の役割 臨床免疫・アレルギー科. 2017.01; 67 (1): 74-81. ( 医中誌 )

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  2. 三宅　健介,　烏山　一: 最近明らかになってきた好塩基球の役割 臨床免疫・アレルギー科. 2015.02; 63 (2): 164-169.

  1. 太田　卓哉,　吉川　宗一郎,　烏山　一: マダニ感染防御と好塩基球 医学のあゆみ. 2014.09; 250 (12): 1114-1118.

  2. 烏山　一: 好塩基球の光と影 ー 体を守るジキル的側面と病気を引き起こすハイド的側面「はじめに」 医学のあゆみ. 2014.09; 250 (12): 1079.

  3. 烏山　一: 特集 Basic Science 炎症の抑制・終焉機構「序」 炎症と免疫. 2014.02; 22 (2): 71.

  4. 壹岐　美紗子,　烏山　一: 免疫システムのキープレイヤー・好塩基球とアレルギー炎症のメカニズム 実験医学増刊. 2014; 32 (17): 2728-2733.

  5. 二宮（小畑）一茂,　筒井英充,　烏山　一: 消化管寄生虫感染防御免疫応答における好塩基球の新たな役割 感染・炎症・免疫. 2014; 44 (1): 30-39.

  1. 烏山一: 呼吸器系の生物学 アレルギーにおける好塩基球の新たな役割 Annual Review呼吸器. 2009; 2009 44-51. ( 医中誌 )

  2. 小島利之, 小畑一茂, 烏山一: 【好塩基球　アップデート】 CD200R3を介した好塩基球とマスト細胞の活性化 アレルギー・免疫. 2009; 16 (3): 340-347. ( 医中誌 )

  3. 峯岸克行, 烏山一: 【臨床でどのようなエビデンスがわかったか】 高IgE症候群の原因遺伝子は何か 分子リウマチ治療. 2009; 2 (3): 123-125. ( 医中誌 )

  4. 小島利之, 小畑一茂, 向井香織, 烏山一: 【自然免疫における活性化レセプターと阻止レセプター】 好塩基球・マスト細胞の機能とCD200R3 臨床免疫・アレルギー科. 2009; 52 (1): 49-57. ( 医中誌 )

  5. 向井香織, 烏山一: 【好塩基球　アップデート】 好塩基球が主役を演じる慢性アレルギー炎症 アレルギー・免疫. 2009; 16 (3): 368-373. ( 医中誌 )

  6. 辻村祐佑, 小畑一茂, 烏山一: 【好塩基球　アップデート】 好塩基球によるIgG型アナフィラキシーの誘導 アレルギー・免疫. 2009; 16 (3): 358-367. ( 医中誌 )

  7. 烏山一: 好塩基球の21世紀ルネサンス　急性ならびに慢性アレルギーにおける好塩基球の新たな役割 アレルギー. 2009; 58 (6): 635-637. ( 医中誌 )

  1. 烏山一: 【最新免疫研究Update　免疫システム研究から免疫疾患の病態制御・治療へ】 アレルギー制御　慢性アレルギー炎症ならびにアナフィラキシーにおける好塩基球のあらたな役割 医学のあゆみ. 2008; 227 (5): 361-366. ( 医中誌 )

  2. 辻村祐佑, 烏山一: アナフィラキシー・ショックを引き起こす新たなメカニズム　好塩基球・IgG・血小板活性化因子を介した即時型アレルギー 細胞工学. 2008; 27 (10): 1030-1031. ( 医中誌 )

  3. 峯岸克行, 齋藤雅子, 烏山一: 免疫疾患の分子基盤最前線 高IgE症候群の分子基盤 日本臨床免疫学会会誌. 2008; 31 (4): 260. ( 医中誌 )

  4. 峯岸克行, 烏山一: 【シグナル伝達研究　2008'09　疾患発症の分子メカニズムと実現化する分子標的薬開発】 シグナル伝達研究　現象から因子へ　STAT3シグナルと免疫疾患 実験医学. 2008; 26 (15): 2432-2436. ( 医中誌 )

  5. 小畑一茂, 小島俊之, 辻村祐佑, 向井香織, 烏山一: 好塩基球とマスト細胞に発現するCD200R3 臨床免疫・アレルギー科. 2008; 50 (5): 595-602. ( 医中誌 )

  6. 烏山一: 見逃されていた好塩基球の重要性　山椒は小粒でもぴりりと辛い 日本臨床免疫学会会誌. 2008; 31 (4): 283. ( 医中誌 )

  7. 峯岸克行, 烏山一: 遺伝子異常により発症するアレルギー 小児科. 2008; 49 (11): 1766-1774. ( 医中誌 )

  8. 烏山一: 基礎医学から　アナフィラキシーショック発症の新たなメカニズム 日本医事新報. 2008; (4402): 45-48. ( 医中誌 )

  9. 烏山一: 医学最新情報　アナフィラキシー・ショックを引き起こす新たな仕組み　好塩基球の知られざる役割が明らかに DENTAL DIAMOND. 2008; 33 (10): 66-70. ( 医中誌 )

  10. 辻村祐佑, 小畑一茂, 烏山一: 【アレルギーの発症にかかわる要因をめぐって】 IgGと好塩基球による新たなアナフィラキシー誘導機構 臨床免疫・アレルギー科. 2008; 49 (6): 651-660. ( 医中誌 )

  11. 横関博雄, 烏山一, 佐藤貴浩: 皮膚アレルギーと好塩基球 皮膚アレルギーフロンティア. 2008; 6 (2): 118-125. ( 医中誌 )

  12. 向井香織, 峯岸克行, 烏山一: Basophils induce alternative activation of macrophages through Th2 cytokine release 日本免疫学会総会・学術集会記録. 2008; 38 46. ( 医中誌 )

  13. 向井香織, 烏山一: マスト細胞・好塩基球の遺伝子発現制御 好塩基球由来Th2サイトカインによるalternative activated macrophageの誘導 アレルギー. 2008; 57 (9-10): 1395. ( 医中誌 )

  14. 烏山一: 好塩基球の21世紀ルネサンス　急性ならびに慢性アレルギーにおける好塩基球の新たな役割 アレルギー. 2008; 57 (9-10): 1231. ( 医中誌 )

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  2. 宇賀神つかさ, 小島利之, 小畑一茂, 辻村祐佑, 向井香織, 河野洋平, 峯岸克行, 横関博雄, 烏山一: 好塩基球に選択的に発現する顆粒酵素に対する特異抗体の樹立とその応用 アレルギー. 2007; 56 (8-9): 1166. ( 医中誌 )

  3. 峯岸克行, 烏山一: カレント・レビュー　免疫学　重症アトピーをともなう難病の原因遺伝子をついに発見 Medical Bio. 2007; 4 (7): 14-15. ( 医中誌 )

  4. 向井香織, 峯岸克行, 烏山一: アトピー性皮膚炎 慢性アレルギー性炎症におけるイニシエーターとしての好塩基球の役割 アレルギー. 2007; 56 (8-9): 1050. ( 医中誌 )

  5. 辻村祐佑, 河野洋平, 峯岸克行, 烏山一: Basophils play a pivotal role in IgG- but not IgE-mediated systemic anaphylaxis 日本免疫学会総会・学術集会記録. 2007; 37 183. ( 医中誌 )

  6. 峯岸克行, 烏山一: 免疫疾患と制御　高IgE症候群の原因遺伝子 Annual Review免疫. 2007; 2008 288-294. ( 医中誌 )

  7. 向井香織, 烏山一: 【IgEをめぐる諸問題】 免疫細胞、炎症細胞を標的としたIgE依存性疾患治療への展望　好塩基球によるIgE依存性慢性アレルギー炎症 アレルギー・免疫. 2007; 14 (2): 180-185. ( 医中誌 )

  8. 辻村祐佑, 河野洋平, 峯岸克行, 烏山一: 好塩基球が中心的な役割りを果たすIgG依存性全身性アナフィラキシー アレルギー. 2007; 56 (8-9): 1165. ( 医中誌 )

  9. 烏山一: 【アレルギー疾患制御の展望】 好塩基球が主役を演じる慢性アレルギー炎症 Medical Science Digest. 2007; 33 (7): 932-935. ( 医中誌 )

  10. 烏山一: 慢性アレルギー炎症における好塩基球の新たな役割 生化学. 2007; 79 (8): 761-768. ( 医中誌 )

  11. 向井香織, 烏山一: 【マスト細胞と好塩基球】 慢性アレルギー炎症における好塩基球の役割 皮膚アレルギーフロンティア. 2007; 5 (1): 25-29. ( 医中誌 )

  12. 烏山一: 【アレルギー研究の最先端】 好塩基球と慢性アレルギー炎症 医学のあゆみ. 2007; 220 (12): 949-952. ( 医中誌 )

  13. 渡邉麻紀, 佐藤貴浩, 烏山一, 横関博雄: IgEは抗原非存在下で好塩基球からMDCを産生させ慢性アレルギー性炎症を増強させる 日本研究皮膚科学会年次学術大会・総会プログラム. 2007; 32回 92. ( 医中誌 )

  1. 烏山一: 好塩基球による新たな慢性アレルギー炎症誘発機構 感染・炎症・免疫. 2006; 36 (1): 76-78. ( 医中誌 )

  2. 河野洋平, 烏山一: 【B細胞の分化とその決定要因】 プレB細胞レセプターの新たな役割　効率のよいBCR形成術 臨床免疫・アレルギー科. 2006; 46 (6): 555-559. ( 医中誌 )

  3. 烏山一: アレルギー性鼻炎のプレーヤーたち　好塩基球 鼻アレルギーフロンティア. 2006; 6 (3): 30-34. ( 医中誌 )

  4. 烏山一, 向井香織: 【免疫研究最前線　2007】 免疫系の破綻と疾患　好塩基球が主役を演じる慢性アレルギー炎症 実験医学. 2006; 24 (20): 3283-3289. ( 医中誌 )

  5. 烏山一: 免疫組織　好塩基球による慢性アレルギー炎症 Annual Review免疫. 2006; 2007 180-186. ( 医中誌 )

  6. 向井香織, 烏山一: 好塩基球によってひき起こされる皮膚慢性アレルギー炎症 アレルギー科. 2006; 21 (6): 590-596. ( 医中誌 )

  7. 向井香織, 烏山一: 好塩基球が中心的な役割を演じる慢性アレルギー炎症 臨床免疫. 2006; 45 (6): 709-713. ( 医中誌 )

  8. 向井香織, 峯岸克行, 烏山一: 好塩基球により引き起こされる慢性アレルギー炎症誘発機構 アレルギー. 2006; 55 (8-9): 1165. ( 医中誌 )

  9. 小畑一茂, 向井香織, 石渡賢治, 渡邊直煕, 峯岸克行, 烏山一: マウス好塩基球特異的モノクローナル抗体の樹立と好塩基球の機能解析 アレルギー. 2006; 55 (8-9): 1201. ( 医中誌 )

  1. 金井康真, 横関博雄, 呉明花, 鷲見浩史, 佐藤貴浩, 片山一朗, 烏山一, 西岡清: STAT6 decoy ODNを用いた抗原特異的IgE誘導性慢性アルレギー炎症反応の解析 日本皮膚科学会雑誌. 2005; 115 (7): 1062. ( 医中誌 )

  2. 久保田俊之, 向井香織, 峯岸克行, 烏山一: αγ2型ヒトFcεRIの発現調節機構の解析 アレルギー. 2005; 54 (8-9): 1063. ( 医中誌 )

  3. 向井香織, 松岡邦枝, 久保田俊之, 峯岸克行, 米川博通, 烏山一: 好塩基球が主役を演じる慢性アレルギー炎症 アレルギー. 2005; 54 (8-9): 1133. ( 医中誌 )

  4. 向井香織, 烏山一: 好塩基球が主役を演じる慢性アレルギー炎症誘発機構 アレルギー科. 2005; 20 (2): 179-185. ( 医中誌 )

  5. 烏山一: 【わかりやすい免疫疾患】　免疫の基礎　免疫系のしくみとその制御　免疫系の細胞とその分化,免疫系の組織 日本医師会雑誌. 2005; 134 (特別1): S28-S32. ( 医中誌 )

  6. 烏山一: 【臨床免疫学　基礎研究の進歩と最新の臨床】　基礎編　免疫担当細胞　B細胞 日本臨床. 2005; 63 (増刊4 臨床免疫学(上)): 130-135. ( 医中誌 )

  7. 横山三紀, 木村智子, 井ノ口仁一, 烏山一, 柳下正樹: 糖脂質によるB細胞受容体の機能制御 脂質生化学研究. 2005; 47 102-104. ( 医中誌 )

  8. 安戸裕貴, 峯岸克行, 水谷修紀, 高見沢勝, 五十嵐隆, 烏山一: B細胞免疫不全および自己免疫疾患マウスにおける軽鎖非依存性μ重鎖の検討 日本小児科学会雑誌. 2005; 109 (2): 260. ( 医中誌 )

  9. 向井香織, 松岡邦枝, 餌取真紀, 山下誠, 久保田俊之, 峯岸克行, 米川博通, 烏山一: 好塩基球が中心的な役割を演じるT細胞・マスト細胞非依存性慢性アレルギー炎症 日本免疫学会総会・学術集会記録. 2005; 35 135. ( 医中誌 )

  10. 久保田俊之, 山本直樹, 向井香織, 峯岸克行, 烏山一: αγ2型ヒトFcεRIの発現調節機構 日本免疫学会総会・学術集会記録. 2005; 35 293. ( 医中誌 )

  11. 小畑一茂, 小島恵理香, 吉川宗一郎, 辻村祐佑, 向井香織, 久保田俊之, 石渡賢治, 渡辺直煕, 烏山一: マウス好塩基球特異的モノクローナル抗体の樹立とその応用 日本免疫学会総会・学術集会記録. 2005; 35 298. ( 医中誌 )

  12. 峯岸克行, 齋藤雅子, 森尾友宏, 上松一永, 原寿郎, 近藤直美, 有賀正, 谷内江昭宏, 土屋滋, 岩田力, 宮脇利男, 野々山恵章, 烏山一: 常染色体劣性高IgE症候群の原因遺伝子の検討 日本免疫学会総会・学術集会記録. 2005; 35 137. ( 医中誌 )

  13. 安戸裕貴, 峯岸克行, 河野洋平, 高見沢勝, 五十嵐隆, 烏山一: 自己免疫疾患モデルマウスにおける軽鎖非依存性μ重鎖に関する検討 日本免疫学会総会・学術集会記録. 2005; 35 207. ( 医中誌 )

  1. 向井香織, 久保田俊之, 峯岸克行, 烏山一: アレルギー疾患モデルマウスを用いた慢性アレルギー炎症誘発機序の解析 アレルギー. 2004; 53 (8-9): 959. ( 医中誌 )

  2. 峯岸克行, 烏山一: 【免疫不全症　そこが知りたい】　ヒトにおけるB細胞の発達過程 小児内科. 2004; 36 (11): 1697-1701. ( 医中誌 )

  3. 烏山一: アレルギーの疾患モデル　IgEトランスジェニックマウスを用いた新たな慢性アレルギー発症機構の解明 アレルギー. 2004; 53 (8-9): 870. ( 医中誌 )

  4. 久保田俊之, 向井香織, 峯岸克行, 烏山一: IgE結合によるFcεRI発現調節機構の解析 アレルギー. 2004; 53 (8-9): 923. ( 医中誌 )

  5. 小俣合歓子, 安冨素子, 山田彰子, 大嶋勇成, 烏山一, 眞弓光文: 抗原特異的IgE存在下での経口抗原曝露に対するT細胞反応性の変化 日本小児アレルギー学会誌. 2004; 18 (4): 505. ( 医中誌 )

  6. 金井康真, 横関博雄, 呉明花, 鷲見浩史, 佐藤貴浩, 片山一朗, 烏山一, 西岡清: STAT6 Decoyを用いたTNP特異的IgE誘導性第3相耳介腫脹反応の抑制 日本皮膚科学会雑誌. 2004; 114 (10): 1683. ( 医中誌 )

  7. 向井香織, 松岡邦枝, 烏山一: IgE/FcεRIを介する新たな慢性アレルギー炎症誘発機構 臨床免疫. 2004; 41 (2): 195-199. ( 医中誌 )

  8. 金井康真, 横関博雄, 呉明花, 鷲見浩史, 佐藤貴浩, 片山一朗, 烏山一, 金田安史, 西岡清: STAT6 Decoyを用いた抗原特異的IgE transgenicマウスの第3相耳介腫脹反応の抑制 日本研究皮膚科学会年次学術大会・総会プログラム. 2004; 29回 132. ( 医中誌 )

  9. 烏山一: 【シクロスポリンの作用　解明された多様性】　遺伝子改変モデル動物で誘導される新たな慢性アレルギー炎症反応に対するシクロスポリンの作用 医薬ジャーナル. 2004; 40 (7): 183-187. ( 医中誌 )

  10. 小俣合歓子, 大嶋勇成, 安冨素子, 山田彰子, 烏山一, 眞弓光文: T細胞の経口免疫寛容成立に及ぼす抗原特異的IgEの影響 アレルギー. 2004; 53 (2-3): 357. ( 医中誌 )

  11. 烏山一: 先端医学講座　IgEトランスジェニックマウスで判明した新たな慢性アレルギー機序 アレルギーの臨床. 2004; 24 (8): 648-651. ( 医中誌 )

  12. 向井香織, 松岡邦枝, 久保田俊之, 佐藤英一郎, 平原一樹, 米川博通, 峯岸克行, 烏山一: アレルギー疾患モデルマウスを用いた慢性アレルギー炎症誘発機序の解析 アレルギー. 2004; 53 (2-3): 290. ( 医中誌 )

  13. 久保田俊之, 久保秀一, 向井香織, 米川博通, 峯岸克行, 烏山一: IgE結合によるFcεRI発現亢進機構の解析 アレルギー. 2004; 53 (2-3): 293. ( 医中誌 )

  14. 向井香織, 久保田俊之, 峯岸克行, 烏山一: IgE/FcεRIを介する新たな慢性アレルギー炎症誘発機序の解析 日本免疫学会総会・学術集会記録. 2004; 34 103. ( 医中誌 )

  15. 金井康真, 横関博雄, 呉明花, 鷲見浩史, 佐藤貴浩, 片山一朗, 烏山一, 西岡清: STAT6 decoy ODNを用いたTNP特異的IgE誘導性第3相耳介腫脹反応の抑制 日本免疫学会総会・学術集会記録. 2004; 34 109. ( 医中誌 )

  16. 井上茜, 篠原久明, 長井良憲, 保田朋波流, 岩倉洋一郎, 反町典子, 烏山一, 三宅健介, 山梨裕司: Dokファミリー分子によるToll-like receptor 4シグナルの抑制機構 日本免疫学会総会・学術集会記録. 2004; 34 52. ( 医中誌 )

  17. 林万紀子, 槙安季子, 辻村祐佑, 土肥多恵子, 水谷修紀, 烏山一, 稲葉カヨ, 反町典子: 樹状細胞およびマクロファージに発現する抑制性レセプターLy49Qのリガンド検索および機能解析 日本免疫学会総会・学術集会記録. 2004; 34 332. ( 医中誌 )

  18. 久保田俊之, 向井香織, 峯岸克行, 烏山一: IgE結合によるFcεRI発現調節機構の解析 日本免疫学会総会・学術集会記録. 2004; 34 310. ( 医中誌 )

  19. 河野洋平, 吉川宗一郎, 峯岸克行, 烏山一: 胎生期B細胞発生におけるプレB細胞レセプターを介した限定的IgH鎖レパトリーの形成 日本免疫学会総会・学術集会記録. 2004; 34 249. ( 医中誌 )

  20. 安戸裕貴, 峯岸克行, 河野洋平, 岩田力, 五十嵐隆, 烏山一: 自己免疫疾患モデルマウスにおける軽鎖非依存性μ重鎖に関する検討 日本免疫学会総会・学術集会記録. 2004; 34 250. ( 医中誌 )

  21. 辻村祐佑, 槙安希子, 林万紀子, 土肥多恵子, 稲葉カヨ, 烏山一, 反町典子: 抑制性レセプターLy49Qによるマクロファージや樹状細胞の細胞接着制御機構 日本免疫学会総会・学術集会記録. 2004; 34 46. ( 医中誌 )

  22. 峯岸克行, 烏山一: 【リンパ球分化の分子メカニズムと疾患】　B細胞分化と疾患　B細胞初期分化異常と疾患 医学のあゆみ. 2004; 211 (6): 663-668. ( 医中誌 )

  1. 辻村祐佑, 反町典子, 小野田敦子, 安達貴弘, 鍔田武志, 稲葉カヨ, 烏山一: 新規抑制性レセプターLy49Qによる細胞接着の制御機構 日本免疫学会総会・学術集会記録. 2003; 33 236. ( 医中誌 )

  2. 峯岸克行, 安戸裕貴, 河野洋平, ConleyMary Ellen, 烏山一: 軽鎖非依存性μ重鎖を発現するトランスジェニックマウスの検討 日本免疫学会総会・学術集会記録. 2003; 33 304. ( 医中誌 )

  3. 久保田俊之, 久保秀一, 反町典子, 米川博通, 烏山一: 【マスト細胞活性化機構の新知見】　IgEによるFcεRI発現調節のメカニズム アレルギー科. 2003; 15 (3): 198-202. ( 医中誌 )

  4. 烏山一, 向井香織, 反町典子, 松岡邦枝, 久保秀一, 米川博通, 佐藤英一郎, 平原一樹: アレルギー性疾患における動物モデル　IgEトランスジェニックマウスにおける遅延型皮膚アレルギー炎症 アレルギー. 2003; 52 (2-3): 231. ( 医中誌 )

  5. 向井香織, 松岡邦枝, 佐藤英一郎, 平原一樹, 反町典子, 烏山一: 【アトピー性皮膚炎に迫る】　アトピー性皮膚炎のモデルマウス 細胞. 2003; 35 (5): 179-182. ( 医中誌 )

  6. 木村純人, 下浜真理子, 根本文子, 坂東由紀, 高田史男, 金兼弘和, 宮脇利男, 烏山一: 原因不明の低身長に免疫不全を合併した男児例　B細胞分化障害の解析 日本小児科学会雑誌. 2003; 107 (2): 298. ( 医中誌 )

  7. 久保田俊之, 久保秀一, 松岡邦枝, 米川博通, 反町典子, 烏山一: IgE結合によるFcεRI発現亢進メカニズムの解明 アレルギー. 2003; 52 (2-3): 342. ( 医中誌 )

  8. 烏山一: 【原発性免疫不全症とゲノム】　ゲノム機能からみたリンパ球の発生と分化　B細胞の発生・分化のゲノム機能 ゲノム医学. 2003; 3 (3): 265-270. ( 医中誌 )

  9. 向井香織, 松岡邦枝, 烏山一: 【アレルギーの動物モデル】　IgEトランスジェニックマウス　IgE/FcεRIを介する新たな慢性アレルギー炎症誘発機構の解明 アレルギー科. 2003; 16 (4): 308-315. ( 医中誌 )

  10. 烏山一: 【免疫2004】　免疫系の形成　最新の研究動向 Mol Med. 2003; 40 (臨増): 2-9. ( 医中誌 )

  11. 向井香織, 松岡邦枝, 久保田俊之, 佐藤英一郎, 平原一樹, 米川博通, 反町典子, 峯岸克行, 烏山一: アレルギー疾患モデルマウスを用いた慢性アレルギー炎症誘発機序の解析 日本免疫学会総会・学術集会記録. 2003; 33 65. ( 医中誌 )

  12. 反町典子, 尾松芳樹, 伊豫田智典, 辻村祐佑, 鴨川由美子, 小野田敦子, 稲葉カヨ, 烏山一: Plasmacytoid DCに発現する新規抑制性レセプターLy49Qの機能解析 日本免疫学会総会・学術集会記録. 2003; 33 97. ( 医中誌 )

  13. 篠原久明, 保田朋波流, 白形正樹, 岩倉洋一郎, 反町典子, 烏山一, 山梨裕司: Toll-Like-Receptor(TLR)シグナルにおける抑制型Dokファミリータンパク質の生理機能 日本免疫学会総会・学術集会記録. 2003; 33 122. ( 医中誌 )

  14. 小野田敦子, 反町典子, 辻村祐佑, 稲葉カヨ, 烏山一: 新規抑制性レセプターLy49Qの同種異系間における多型解析 日本免疫学会総会・学術集会記録. 2003; 33 143. ( 医中誌 )

  15. 久保田俊之, 久保秀一, 向井香織, 米川博通, 反町典子, 峯岸克行, 烏山一: 高親和性IgE受容体FcεRIの発現調節におけるα鎖膜直上領域の役割 日本免疫学会総会・学術集会記録. 2003; 33 158. ( 医中誌 )

  1. 烏山一: B細胞発生・分化の分子制御機構とその破綻 感染・炎症・免疫. 2002; 32 (4): 248-257. ( 医中誌 )

  2. 久保田俊之, 久保秀一, 松岡邦枝, 米川博通, 反町典子, 烏山一: FcεRIの発現調節におけるFcεRIα鎖細胞内領域の役割 日本免疫学会総会・学術集会記録. 2002; 32 261. ( 医中誌 )

  3. 寺内公一, 白形正樹, 反町典子, 烏山一, 山梨裕司, 麻生武志: 胎盤栄養膜細胞MHCクラスI分子のヒトサイトメガロウイルス感染抵抗性 日本免疫学会総会・学術集会記録. 2002; 32 189. ( 医中誌 )

  4. 河野洋平, 土屋輝一郎, 永田喜三郎, 辻村祐佑, 小島利之, 反町典子, 烏山一: ablによりチロシンリン酸化される新規タンパク質pp36の性状解析 日本免疫学会総会・学術集会記録. 2002; 32 87. ( 医中誌 )

  5. 反町典子, 丸谷美香子, 烏山一: 新規Ly49ファミリー分子Ly49Qのマクロファージ機能調節 日本免疫学会総会・学術集会記録. 2002; 32 137. ( 医中誌 )

  6. 南順子, 反町典子, 烏山一, 安藤登, 江石義信: P.acnes菌体成分トリガーファクター蛋白抗原に対する免疫反応性の誘導と肉芽腫形成の維持 サルコイドーシス/肉芽腫性疾患. 2002; 22 (2): 33. ( 医中誌 )

  7. 前澤裕子, 熊野浩太郎, 中島裕史, 岩本逸夫, 齋藤康, 久保秀一, 烏山一: 抗原誘発気道炎症細胞浸潤におけるマスト細胞の役割 アレルギー. 2002; 51 (9-10): 995. ( 医中誌 )

  8. 烏山一: 【免疫研究の最前線　高次複雑系免疫システムの包括的理解をめざして】　リンパ球分化の分子メカニズム　プレB細胞レセプターを介するB細胞分化誘導 蛋白質・核酸・酵素. 2002; 47 (16): 2182-2187. ( 医中誌 )

  1. 反町典子, 丸谷美香子, 八木田秀雄, 小安重夫, 烏山一: 新規のLy-49ファミリー分子,Ly-49Qのユニークな性状と機能 日本免疫学会総会・学術集会記録. 2001; 31 104. ( 医中誌 )

  2. 川島育夫, 吉田雪子, 多屋長治, 設楽浩志, 米川博通, 烏山一, 田井直: 抗ガングリオシド抗体発現トランスジェニックマウスの腫瘍免疫療法モデルとしての有用性 生化学. 2001; 73 (8): 1046. ( 医中誌 )

  3. 佐藤英一郎, 平原一樹, 烏山一, 白石明郎: 【アトピー性皮膚炎に関する最近の知見】　アトピー性皮膚疾患モデル遺伝子改変マウス 臨床免疫. 2001; 36 (4): 552-557. ( 医中誌 )

  4. 松岡邦枝, 久保秀一, 多屋長治, 佐藤英一郎, 平原一樹, 白石明郎, 米川博通, 烏山一: 抗原特異的IgEによって誘発される超遅発性皮膚反応の解析 日本免疫学会総会・学術集会記録. 2001; 31 36. ( 医中誌 )

  5. 田口智子, 清河信敬, 三森謙一, 鈴木東洋, 齋藤正博, 関野貴臣, 中島英規, 片桐洋子, 松尾良信, 烏山一, 他: pre-B細胞のCD24誘導性アポトーシスとpre-BCR刺激によるその抑制　GEM-膜脂質マイクロドメインを介するMAPキナーゼ活性化の関与 日本免疫学会総会・学術集会記録. 2001; 31 93. ( 医中誌 )

  6. 久保秀一, 遠藤順治, 松岡邦枝, 多屋長治, 烏山一, 吉澤靖之, 米川博通: IgEトランスジェニックマウスを用いたIgE依存性喘息反応及びαβT細胞とγδT細胞の役割の解析 日本免疫学会総会・学術集会記録. 2001; 31 35. ( 医中誌 )

  7. 久保秀一, 松岡邦枝, 烏山一: 高IgE血症とモデルマウス アレルギー科. 2001; 11 (6): 541-547. ( 医中誌 )

  8. 土屋輝一郎, 永田喜三郎, 真木一茂, 篠原久明, 河野洋平, 高尾敏文, 岡田雅人, 北村大介, 烏山一: ラフトに局在する新規アダプター分子BARPは刺激依存的にBLNKをラフトにリクルートする 日本免疫学会総会・学術集会記録. 2001; 31 92. ( 医中誌 )

  9. 真木一茂, 烏山一: リンパ球系　B細胞の初期分化と転写因子 Annual Review血液. 2001; 2001 121-129. ( 医中誌 )

  10. 佐藤英一郎, 平原一樹, 烏山一, 白石明郎: 【IgEとアレルギー】　IgEトランスジェニックマウスにおける三相性耳介肥厚反応 アレルギー科. 2001; 11 (6): 484-490. ( 医中誌 )

  11. 真木一茂, 烏山一: 【抗原レセプター遺伝子の再構成とクラススイッチの制御機構】　プレB細胞レセプターによる免疫グロブリン遺伝子再構成の制御 実験医学. 2001; 19 (5): 538-544. ( 医中誌 )

  12. 反町典子, 小安重夫, 烏山一: 【免疫細胞による抗原提示と抗原認識機構】　NK細胞の標的識別とウイルスのエスケープ機構 実験医学. 2001; 19 (5): 614-620. ( 医中誌 )

  13. 烏山一: 【臨床に活かす免疫学】　免疫担当細胞のはたらき　B細胞と免疫グロブリン Medicina. 2001; 38 (6): 929-931. ( 医中誌 )

  1. 関野貴臣, 清河信敬, 国仲伸男, 烏山一, 藤本純一郎: 代替L鎖λ5のB細胞リンパ腫診断における意義 日本病理学会会誌. 2000; 89 (1): 333. ( 医中誌 )

  2. 真木一茂, 烏山一: 【抗原認識と抗体産生】　B細胞の初期分化から成熟まで 臨床検査. 2000; 44 (4): 373-381. ( 医中誌 )

  3. 反町典子, 小安重夫, 烏山一: 【免疫システムを支える抗原情報伝達の多様な分子機構】　NK細胞が持つ正と負の標的認識機構 細胞工学. 2000; 19 (2): 255-262. ( 医中誌 )

  4. 真木一茂, 烏山一: プレB細胞レセプターによる免疫グロブリン遺伝子再構成の制御 免疫Immunology Frontier. 2000; 10 (6): 365-371. ( 医中誌 )

  5. 川島育夫, 吉田雪子, 烏山一, 多屋長治, 設楽浩志, 米川博通, 古川鋼一, 田井直: 腫瘍免疫療法モデル動物としての抗ガングリオシド抗体発現トランスジェニックマウスの作製 生化学. 2000; 72 (8): 1037. ( 医中誌 )

  6. 永田喜三郎, 岡田雅人, 真木一茂, 土屋輝一郎, 北村ふじ子, 烏山一: プレB細胞レセプターを介するシグナルに重要な36kDタンパク質の機能解析 日本免疫学会総会・学術集会記録. 2000; 30 327. ( 医中誌 )

  7. 大西和夫, メルヒャース・フリッツ, 烏山一, 清水健之: B細胞に発現するカドヘリン分子 日本免疫学会総会・学術集会記録. 2000; 30 198. ( 医中誌 )

  8. 反町典子, 田口由利子, 八木田秀雄, 川崎明美, 北村ふじ子, 小安重夫, 烏山一: NK細胞の自己識別におけるCD94の役割 日本免疫学会総会・学術集会記録. 2000; 30 322. ( 医中誌 )

  9. 田口智子, 清河信敬, 鈴木東洋, 関野貴臣, 中島英規, 片桐洋子, 烏山一, 松尾良信, 藤本純一郎: Pre-BCRの架橋刺激はCD24を介するpre-B細胞のアポトーシス誘導に抑制的に作用する 日本免疫学会総会・学術集会記録. 2000; 30 248. ( 医中誌 )

  10. 久保秀一, 松岡邦枝, 烏山一: IgEトランスジェニックマウスにおけるFcεRIの高発現 アレルギー科. 2000; 10 (3): 232-238. ( 医中誌 )

  11. 久保秀一, 松岡邦枝, 多屋長治, 北村ふじ子, 高井俊行, 米川博通, 烏山一: IgEによるFcεRI発現上昇の機構とそれに伴うマスト細胞の短期記憶の形成 日本免疫学会総会・学術集会記録. 2000; 30 41. ( 医中誌 )

  12. 久保秀一, 松岡邦枝, 烏山一: 【アレルギーの発症機構をめぐって】　IgEによるマスト細胞FcεRIの表出制御 臨床免疫. 2000; 33 (6): 654-658. ( 医中誌 )

  13. 久保秀一, 松岡邦枝, 烏山一: 【アトピー性皮膚炎の新しい展開】　アトピー性皮膚炎モデル動物　IgEトランスジェニックマウス アレルギー・免疫. 2000; 7 (8): 1065-1073. ( 医中誌 )

  14. 松岡邦枝, 久保秀一, 烏山一: アレルギーのモデル動物　抗原特異的IgEトランスジェニックマウス 組織培養工学. 2000; 26 (8): 335-339. ( 医中誌 )

  15. 永田喜三郎, 烏山一: 【免疫担当細胞上の細胞表面分子とその機能】　B細胞の分化と機能発現に関わる分子　プレB細胞受容体 臨床免疫. 2000; 34 (Suppl.19): 165-170. ( 医中誌 )

  16. 松岡邦枝, 久保秀一, 多屋長治, 北村ふじ子, 米川博通, 烏山一: ヒト型アレルギーモデルマウスの樹立と解析 アレルギー. 2000; 49 (9-10): 1005. ( 医中誌 )

  17. 佐藤英一郎, 平原一樹, 和田吉弘, 小林和彦, 安藤洋介, 松岡邦枝, 久保秀一, 烏山一, 白石明郎: IgEトランスジェニックマウスにおける抗原特異的な三相性耳浮腫反応 日本免疫学会総会・学術集会記録. 2000; 30 34. ( 医中誌 )

  18. 反町典子, 小安重夫, 烏山一: 生体防御と糖鎖シグナル　NK細胞の標的認識に関わるC型レクチンの機能と発現調節機構 生化学. 2000; 72 (8): 600. ( 医中誌 )

  19. 反町典子, 小安重夫, 烏山一: マウスNK細胞の標的認識及び分化におけるCD94の役割 日本癌学会総会記事. 2000; 59回 428-429. ( 医中誌 )

  1. 真木一茂, 永田喜三郎, 北村ふじ子, 生田宏一, 烏山一: 免疫グロブリン遺伝子の組換え制御におけるプレB細胞レセプターとIL-7レセプターの役割 日本免疫学会総会・学術集会記録. 1999; 29 102. ( 医中誌 )

  2. 遠藤順治, 反町典子, 宮川敏美, 永田喜三郎, 杭田慶介, 多屋長治, 米川博通, 烏山一: LOKノックアウトマウス由来のConA誘導リンパ芽球におけるLFA-1キャッピング形成の亢進 日本免疫学会総会・学術集会記録. 1999; 29 219. ( 医中誌 )

  3. 久保秀一, 松岡邦枝, 多屋長治, 北村ふじ子, 羅智靖, 米川博通, 烏山一: IgEトランスジェニックマウスにおけるFcεRIの高発現とIgEによるFcεRIの安定化 日本免疫学会総会・学術集会記録. 1999; 29 78. ( 医中誌 )

  4. 真木一茂, 永田喜三郎, 烏山一: 【臨床遺伝子学'99　免疫研究の最前線】　リンパ球の発生・分化　プレB細胞受容体による免疫グロブリン遺伝子再構成の制御 最新医学. 1999; 54 (増刊): 2136-2144. ( 医中誌 )

  5. 烏山一: リンパ球の分化と機能　B細胞初期分化 日本医学会総会会誌. 1999; 25回 (I): 208. ( 医中誌 )

  6. 松岡邦枝, 久保秀一, 多屋長治, 米川博通, 烏山一: 卵白アルブミン特異的IgEトランスジェニックマウスの樹立とアレルギー反応の誘発 日本免疫学会総会・学術集会記録. 1999; 29 85. ( 医中誌 )

  7. 野村恵子, 金兼弘和, 塚田聡, 烏山一, 上松一永, 小宮山淳, 宮脇利男: X連鎖無γグロブリン血症における骨髄B前駆細胞の解析 日本免疫学会総会・学術集会記録. 1999; 29 210. ( 医中誌 )

  8. 反町典子, 田口由利子, 小安重夫, 烏山一: 新規NKレセプターに対するモノクローナル抗体の性状解析 日本免疫学会総会・学術集会記録. 1999; 29 271. ( 医中誌 )

  9. 金山直樹, 疋田正喜, 烏山一, 大森斉: 胚中心B細胞におけるRAGと並行するλ5,VpreBの再発現とその調節 日本免疫学会総会・学術集会記録. 1999; 29 103. ( 医中誌 )

  10. 久保秀一, 烏山一: 【アレルギーの抑制機構　分子細胞生物学的観点から】　B細胞の抑制性シグナル アレルギー科. 1999; 7 (6): 478-484. ( 医中誌 )

  11. 真木一茂, 烏山一: 【疾患モデル動物】　B細胞免疫不全症　Xidマウス,IgH鎖遺伝子KOマウス 血液・免疫・腫瘍. 1999; 4 (3): 307-311. ( 医中誌 )

  12. 久保秀一, 松岡邦枝, 烏山一: 【環境応答・適応の分子機構】　動物における環境適応の分子機構　環境適応とその破綻と疾患　アトピー過敏症　アレルゲン特異的IgEトランスジェニックマウス 蛋白質・核酸・酵素. 1999; 44 (15): 2523-2528. ( 医中誌 )

  13. 西原政道, 石井武文, 烏山一, 浅野茂隆, 中畑龍俊, 前川平: ヒトBリンパ球前駆細胞の代替軽鎖発現動態の解析 日本免疫学会総会・学術集会記録. 1999; 29 101. ( 医中誌 )

  14. 松岡邦枝, 久保秀一, 多屋長治, 米川博通, 烏山一: 誘発型アレルギーモデル動物　抗卵白アルブミン-IgEトランスジェニックマウスの樹立と解析 アレルギー. 1999; 48 (8-9): 1014. ( 医中誌 )

  15. 久保秀一, 松岡邦枝, 多屋長治, 北村ふじ子, 羅智博, 米川博通, 烏山一: IgEトランスジェニックマウスにおけるFcεRIの発現増強とアレルギー反応性の亢進　IgEの積極的なアレルギー感受性への関与 アレルギー. 1999; 48 (8-9): 978. ( 医中誌 )

  16. 西原政道, 石井武文, 海老原康博, 辻浩一郎, 浅野茂隆, 烏山一, 中畑龍俊, 前川平: ヒトBリンパ球前駆細胞の初期分化過程における代替軽鎖発現動態の解析 Int J Hematol. 1999; 69 (Suppl.1): 139. ( 医中誌 )

  17. 烏山一: B細胞初期分化とプレB細胞レセプターの発現 医学のあゆみ. 1999; 188 (3): 202-203. ( 医中誌 )

  18. 田口智子, 清河信敬, 烏山一, 藤本純一郎: pro-B ALL細胞株においてLyn及びHckはpro-B細胞受容体と会合する Int J Hematol. 1999; 69 (Suppl.1): 119. ( 医中誌 )

  1. 烏山一: 【リンパ細胞分化と活性化】　B細胞分化におけるプレB細胞レセプターシグナルの役割 蛋白質・核酸・酵素. 1998; 43 (2): 111-118. ( 医中誌 )

  2. 永田喜三郎, 烏山一: 【B細胞レセプターシグナル】　プレB細胞レセプターの役割とシグナル伝達 臨床免疫. 1998; 30 (5): 593-600. ( 医中誌 )

  3. 烏山一: I型アレルギーモデルマウスの開発 免疫Immunology Frontier. 1998; 8 (4): 231-233. ( 医中誌 )

  4. 烏山一: 【免疫1998-99】　免疫系の分子発生生物学　プレB細胞レセプターのシグナル Mol Med. 1998; 35 (臨増 免疫1998-99号): 36-46. ( 医中誌 )

  5. 倉持敏美, 杭田慶介, 烏山一: セリン/スレオニンキナーゼLOKはCaspase-3で切断され,核に移行する 日本臨床免疫学会会誌. 1998; (26回抄録集): 295. ( 医中誌 )

  6. 清水一宏, 植村天受, 仲川嘉紀, 平尾佳彦, 佐賀信介, 烏山一, 吉川和宏: 免疫治療モデルとしてのMN/CA9遺伝子導入マウス由来腎細胞癌株の樹立 日本癌学会総会記事. 1998; 57回 699. ( 医中誌 )

  7. 永田喜三郎, 烏山一: B細胞・免疫グロブリン　B細胞の初期分化 Annual Review免疫. 1998; 1999 1-13. ( 医中誌 )

  8. 遠藤順治, 反町典子, 倉持敏美, 永田喜三郎, 杭田慶介, 多屋長治, 米川博通, 烏山一: LOKノックアウトマウスにおけるリンパ球接着性の亢進 日本臨床免疫学会会誌. 1998; (26回抄録集): 254. ( 医中誌 )

  9. 反町典子, 小安重夫, 烏山一: 新規NKレセプターに対するモノクローナル抗体の樹立及びその性状解析 日本臨床免疫学会会誌. 1998; (26回抄録集): 355. ( 医中誌 )

  10. 真木一茂, 永田喜三郎, 北村ふじ子, 中村哲也, 烏山一: プレB細胞レセプターによる免疫グロブリン遺伝子組み換え制御機構の解析 日本臨床免疫学会会誌. 1998; (26回抄録集): 218. ( 医中誌 )

  11. 宮崎宇広, 烏山一, 須藤哲央, 竹下淳, 工藤明: 免疫グロブリン遺伝子再構成におけるSL鎖の役割 日本臨床免疫学会会誌. 1998; (26回抄録集): 219. ( 医中誌 )

  12. 永田喜三郎, 真木一茂, 北村ふじ子, 中村哲也, 烏山一: 胎児肝臓組織培養を用いたプレB細胞レセプターシグナルによるB細胞初期分化の誘導 日本臨床免疫学会会誌. 1998; (26回抄録集): 222. ( 医中誌 )

  13. 津金沢恵子, 北村ふじ子, 松尾良信, 清河信敬, 藤本純一郎, 烏山一: プロB細胞・プレB細胞に特異的に反応する新規モノクローナル抗体を用いたヒト白血病細胞の解析と診断への応用 日本癌学会総会記事. 1998; 57回 617. ( 医中誌 )

  14. 久保秀一, 松岡邦枝, 多屋長治, 北村ふじ子, 羅智靖, 米川博通, 烏山一: 抗原特異的IgEトランスジェニックマウスの樹立　新しいアレルギー誘発モデルマウス アレルギー. 1998; 47 (9-10): 1017. ( 医中誌 )

  15. 梶原道子, 大川洋二, 津金沢恵子, 烏山一: 急性リンパ性白血病細胞でのプレB細胞レセプター発現の検討 臨床血液. 1998; 39 (10): 1065. ( 医中誌 )

  1. 倉持敏美, 烏山一: B細胞の分化とプレB細胞レセプター 臨床免疫. 1997; 29 (8): 961-967. ( 医中誌 )

  2. 永田喜三郎, 烏山一: B細胞の分化 アレルギー科. 1997; 4 (5): 485-492. ( 医中誌 )

  3. 烏山一: 免疫制御機構に関する研究(老化,免疫低下等を含む)　プレB細胞レセプターを介するシグナル伝達経路の解明 持田記念財団研究成果報告集. 1997; 13 102-107. ( 医中誌 )

  4. 烏山一: 免疫系の発生と分化　B細胞の発生と分化　B細胞初期分化の分子機構 実験医学. 1997; 15 (11): 1273-1280. ( 医中誌 )

  5. 烏山一: B細胞の分化 日本臨床免疫学会会誌. 1997; 20 (4): 245. ( 医中誌 )

  6. 烏山一: 造血幹細胞からのBリンパ球の分化 Mebio. 1997; 14 (4): 66-73. ( 医中誌 )

  7. 烏山一: リンパ球初期分化におけるシグナル伝達 最新医学. 1997; 52 (4): 744-749. ( 医中誌 )

  8. 烏山一: B細胞分化の分子制御機構 Mebio. 1997; 14 (7): 70-75. ( 医中誌 )

  1. 烏山一: B細胞分化におけるプレB細胞レセプターの役割 臨床免疫. 1996; 28 (7): 815-821. ( 医中誌 )

  2. 烏山一: 抗体遺伝子とB細胞分化 日本医事新報ジュニア版. 1996; (356): 13-15. ( 医中誌 )

  3. 烏山一, 他: B細胞分化の分子制御機構 生化学. 1996; 68 (7): 554. ( 医中誌 )

  4. 烏山一: 新免疫学講座　B細胞分化の制御と異常 日本医事新報ジュニア版. 1996; (357): 15-17. ( 医中誌 )

  5. 烏山一: B細胞・免疫グロブリンと疾患　B細胞初期分化の分子機構 Mol Med. 1996; 34 (1): 25-34. ( 医中誌 )

  6. 烏山一: B細胞分化とシグナル伝達 実験医学. 1996; 14 (6): 714-720. ( 医中誌 )

  7. 烏山一: 免疫学講座　B細胞の分化 細胞工学. 1996; 15 (5): 689-697. ( 医中誌 )

  1. 烏山一: リンパ球の発生分化　B細胞初期分化におけるSL鎖の役割 Mol Med. 1995; 32 (臨増): 158-168. ( 医中誌 )

  2. 烏山一: B細胞分化制御分子surrogate light chain 免疫Immunology Frontier. 1995; 5 (2): 95-101. ( 医中誌 )

  3. 烏山一: B細胞初期分化と代替軽鎖(surrogate light chain) Annual Review免疫. 1995; 1996 31-38. ( 医中誌 )

  1. 烏山一: リンパ球の腫瘍化とサイトカイン 臨床医. 1992; 18 (2): 154-157. ( 医中誌 )

  1. 烏山一: 免疫応答の機構 プレB細胞表面レセプター 代謝. 1991; 28 (増刊): 29-36. ( 医中誌 )

  2. 烏山一: リンフォカイン産生とリンパ球の腫瘍化 免疫Immunology Frontier. 1991; 1 (3): 9-14. ( 医中誌 )

  3. 烏山一, 工藤明: プレB細胞特異的Vpre B,λ5タンパクの解析 Medical Immunology. 1991; 22 (1): 47-55. ( 医中誌 )

  1. 烏山一, 他: プレB細胞特異的に発現するVpreBおよびλ5の遺伝子産物はμ鎖とIg様複合体を形成する 日本免疫学会総会・学術集会記録. 1990; 20 379. ( 医中誌 )

  1. 烏山一, 他: c-mycアンチセンスRNAによる形質細胞腫の増殖抑制 日本免疫学会総会・学術集会記録. 1989; 19 360. ( 医中誌 )

  2. 烏山一: 分子生物学・バイオテクノロジー研究の素材として ウシパピローマウイルスベクター 実験医学. 1989; 7 (17): 2059-2061. ( 医中誌 )

  1. 烏山一, 他: 遺伝子導入によりIL-2autocrine機序が成立したT細胞株の自己増殖能および造腫瘍性の検討 日本癌学会総会記事. 1988; 47回 87. ( 医中誌 )

  2. 烏山一, 遠山典子: IL-2オートクリン機序とT細胞の悪性腫瘍化 代謝. 1988; 25 (12臨増): 33-39. ( 医中誌 )

  3. 烏山一: 高率cDNA発現用ベクターによるインターロイキンの大量生産 蛋白質・核酸・酵素. 1988; 33 (14): 2527-2532. ( 医中誌 )

  1. 烏山一, 他: 高率発現用ベクターを用いた単一リコンビナント・インターロイキン(IL-2,IL-3,IL-4,IL-5)大量分泌細胞株の樹立 日本免疫学会総会・学術集会記録. 1987; 17 455. ( 医中誌 )

  2. 烏山一: 高率cDNA発現用ベクターの作製とその応用 単一インターロイキン(IL-2,IL-3,IL-4,IL-5)大量分泌細胞株の樹立 代謝. 1987; 24 (臨増): 179-188. ( 医中誌 )

  1. 烏山一, 奥村康: モノクローナル抗体で検出されるIgh遺伝子に連鎖したT細胞アロ抗原の多様性 代謝. 1983; 20 (11臨増): 1405-1412. ( 医中誌 )

  1. 烏山一: 機能的T細胞サブセットに表現されたIgアロタイプ連鎖遺伝子産物(CT)と反応する単一クローン性抗体 日本免疫学会総会記録. 1982; 12 616-617. ( 医中誌 )

  1. Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes 2020.12; ( DOI )

  1. Abe K, Irie K, Nakanishi H, Suzuki H, Fujiyoshi Y: Crystal structures of the gastric proton pump. Nature. 2018.04; 556 (7700): 214-218. ( PubMed , DOI )

  2. Nakamura S, Fujiyoshi Y, Irie K: Enhancement of the thermostability of mouse claudin-3 on complex formation with the carboxyl-terminal region of Clostridium perfringens enterotoxin improves crystal quality. Acta crystallographica. Section F, Structural biology communications. 2018.03; 74 (Pt 3): 150-155. ( PubMed , DOI )

  3. Irie K, Haga Y, Shimomura T, Fujiyoshi Y: Optimized expression and purification of NavAb provide the structural insight into the voltage dependence. FEBS letters. 2018.01; 592 (2): 274-283. ( PubMed , DOI )

  1. Shihoya W, Nishizawa T, Yamashita K, Inoue A, Hirata K, Kadji FMN, Okuta A, Tani K, Aoki J, Fujiyoshi Y, Doi T, Nureki O: X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog. Nature structural & molecular biology. 2017.09; 24 (9): 758-764. ( PubMed , DOI )

  2. Abe K, Shimokawa J, Naito M, Munson K, Vagin O, Sachs G, Suzuki H, Tani K, Fujiyoshi Y: The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors. Scientific reports. 2017.07; 7 (1): 6632. ( PubMed , DOI )

  3. Suzuki H, Tani K, Fujiyoshi Y: Crystal structures of claudins: insights into their intermolecular interactions. Annals of the New York Academy of Sciences. 2017.06; 1397 (1): 25-34. ( PubMed , DOI )

  1. Oshima A, Tani K, Fujiyoshi Y: Atomic structure of the innexin-6 gap junction channel determined by cryo-EM. Nature communications. 2016.12; 7 13681. ( PubMed , DOI )

  2. Shihoya W, Nishizawa T, Okuta A, Tani K, Dohmae N, Fujiyoshi Y, Nureki O, Doi T: Activation mechanism of endothelin ETB receptor by endothelin-1. Nature. 2016.09; 537 (7620): 363-368. ( PubMed , DOI )

  3. Shimomura T, Irie K, Fujiyoshi Y: Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics. The FEBS journal. 2016.08; 283 (15): 2881-2895. ( PubMed , DOI )

  4. Abe K, Fujiyoshi Y: Cryo-electron microscopy for structure analyses of membrane proteins in the lipid bilayer. Current opinion in structural biology. 2016.08; 39 71-78. ( PubMed , DOI )

  5. Okuta A, Tani K, Nishimura S, Fujiyoshi Y, Doi T: Thermostabilization of the Human Endothelin Type B Receptor. Journal of molecular biology. 2016.06; 428 (11): 2265-2274. ( PubMed , DOI )

  6. Kamegawa A, Hiroaki Y, Tani K, Fujiyoshi Y: Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide. Microscopy (Oxford, England). 2016.04; 65 (2): 177-184. ( PubMed , DOI )

  7. Nagura H, Doi T, Fujiyoshi Y: Characterization of physiological phenotypes of dentate gyrus synapses of PDZ1/2 domain-deficient PSD-95-knockin mice. The European journal of neuroscience. 2016.03; 43 (5): 618-625. ( PubMed , DOI )

  8. Oshima A, Matsuzawa T, Murata K, Tani K, Fujiyoshi Y: Hexadecameric structure of an invertebrate gap junction channel. Journal of molecular biology. 2016.03; 428 (6): 1227-1236. ( PubMed , DOI )

  9. Tanaka H, Yamamoto Y, Kashihara H, Yamazaki Y, Tani K, Fujiyoshi Y, Mineta K, Takeuchi K, Tamura A, Tsukita S: Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Molecular and cellular biology. 2016.01; 36 (6): 954-964. ( PubMed , DOI )

  10. Bando Y, Irie K, Shimomura T, Umeshima H, Kushida Y, Kengaku M, Fujiyoshi Y, Hirano T, Tagawa Y: Control of Spontaneous Ca2+ Transients Is Critical for Neuronal Maturation in the Developing Neocortex. Cerebral cortex (New York, N.Y. : 1991). 2016.01; 26 (1): 106-117. ( PubMed , DOI )

  1. Hauer F, Gerle C, Fischer N, Oshima A, Shinzawa-Itoh K, Shimada S, Yokoyama K, Fujiyoshi Y, Stark H: GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM. Structure (London, England : 1993). 2015.09; 23 (9): 1769-1775. ( PubMed , DOI )

  2. Minatohara K, Murata Y, Fujiyoshi Y, Doi T: An intracellular domain with a novel sequence regulates cell surface expression and synaptic clustering of leucine-rich repeat transmembrane proteins in hippocampal neurons. Journal of neurochemistry. 2015.08; 134 (4): 618-628. ( PubMed , DOI )

  3. Jiko C, Davies KM, Shinzawa-Itoh K, Tani K, Maeda S, Mills DJ, Tsukihara T, Fujiyoshi Y, Kühlbrandt W, Gerle C: Bovine F1Fo ATP synthase monomers bend the lipid bilayer in 2D membrane crystals. eLife. 2015.03; 4 e06119. ( PubMed , DOI )

  4. Saitoh Y, Suzuki H, Tani K, Nishikawa K, Irie K, Ogura Y, Tamura A, Tsukita S, Fujiyoshi Y: Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin. Science (New York, N.Y.). 2015.02; 347 (6223): 775-778. ( PubMed , DOI )

  5. Suzuki H, Tani K, Tamura A, Tsukita S, Fujiyoshi Y: Model for the architecture of claudin-based paracellular ion channels through tight junctions. Journal of molecular biology. 2015.01; 427 (2): 291-297. ( PubMed , DOI )

  6. Fujiyoshi Y: Development of the field of structural physiology. Proceedings of the Japan Academy. Series B, Physical and biological sciences. 2015; 91 (9): 447-468. ( PubMed , DOI )

  1. Abe K, Tani K, Fujiyoshi Y: Systematic comparison of molecular conformations of H+,K+-ATPase reveals an important contribution of the A-M2 linker for the luminal gating. The Journal of biological chemistry. 2014.10; 289 (44): 30590-30601. ( PubMed , DOI )

  2. Tani K, Fujiyoshi Y: Water channel structures analysed by electron crystallography. Biochimica et biophysica acta. 2014.05; 1840 (5): 1605-1613. ( PubMed , DOI )

  3. Suzuki H, Nishizawa T, Tani K, Yamazaki Y, Tamura A, Ishitani R, Dohmae N, Tsukita S, Nureki O, Fujiyoshi Y: Crystal structure of a claudin provides insight into the architecture of tight junctions. Science (New York, N.Y.). 2014.04; 344 (6181): 304-307. ( PubMed , DOI )

  4. Morito D, Nishikawa K, Hoseki J, Kitamura A, Kotani Y, Kiso K, Kinjo M, Fujiyoshi Y, Nagata K: Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state. Scientific reports. 2014.03; 4 4442. ( PubMed , DOI )

  1. Yang F, Abe K, Tani K, Fujiyoshi Y: Carbon sandwich preparation preserves quality of two-dimensional crystals for cryo-electron microscopy. Microscopy (Oxford, England). 2013.12; 62 (6): 597-606. ( PubMed , DOI )

  2. Tsai CJ, Tani K, Irie K, Hiroaki Y, Shimomura T, McMillan DG, Cook GM, Schertler GF, Fujiyoshi Y, Li XD: Two alternative conformations of a voltage-gated sodium channel. Journal of molecular biology. 2013.11; 425 (22): 4074-4088. ( PubMed , DOI )

  3. Tani K, Arthur CP, Tamakoshi M, Yokoyama K, Mitsuoka K, Fujiyoshi Y, Gerle C: Visualization of two distinct states of disassembly in the bacterial V-ATPase from Thermus thermophilus. Microscopy (Oxford, England). 2013.08; 62 (4): 467-474. ( PubMed , DOI )

  4. Fujiyoshi Y, Tanji T, Osakabe N, Hirayama T: Special Issue: "Tribute to Akira Tonomura". Foreword. Microscopy (Oxford, England). 2013.06; 62 Suppl 1 S1. ( PubMed , DOI )

  5. Oshima A, Matsuzawa T, Nishikawa K, Fujiyoshi Y: Oligomeric structure and functional characterization of Caenorhabditis elegans Innexin-6 gap junction protein. The Journal of biological chemistry. 2013.04; 288 (15): 10513-10521. ( PubMed , DOI )

  6. Mori H, Fujiyoshi Y: Preface on the occasion of the inauguration issue of Microscopy. Microscopy (Oxford, England). 2013.02; 62 (1): 1-2. ( PubMed , DOI )

  7. Goda M, Fujiyoshi Y, Sugimoto M, Fujii R: Novel dichromatic chromatophores in the integument of the mandarin fish Synchiropus splendidus. The Biological bulletin. 2013.02; 224 (1): 14-17. ( PubMed , DOI )

  8. Minatohara K, Ichikawa SH, Seki T, Fujiyoshi Y, Doi T: Ligand binding of PDZ domains has various roles in the synaptic clustering of SAP102 and PSD-95. Neuroscience letters. 2013.01; 533 44-49. ( PubMed , DOI )

  9. Fujiyoshi Y: Low dose techniques and cryo-electron microscopy. Methods in molecular biology (Clifton, N.J.). 2013; 955 103-118. ( PubMed , DOI )

  10. Fujiyoshi Y: Future directions of electron crystallography. Methods in molecular biology (Clifton, N.J.). 2013; 955 551-568. ( PubMed , DOI )

  11. Suzuki H, Ito Y, Yamazaki Y, Mineta K, Uji M, Abe K, Tani K, Fujiyoshi Y, Tsukita S: The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat. Nature communications. 2013; 4 1766. ( PubMed , DOI )

  1. Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, Tamura H, Shiosaka S, Suzuki H, Miyakawa T, Fujiyoshi Y, Doi T: Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. Molecular brain. 2012.12; 5 43. ( PubMed , DOI )

  2. Abe K, Tani K, Friedrich T, Fujiyoshi Y: Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site. Proceedings of the National Academy of Sciences of the United States of America. 2012.11; 109 (45): 18401-18406. ( PubMed , DOI )

  3. Unwin N, Fujiyoshi Y: Gating movement of acetylcholine receptor caught by plunge-freezing. Journal of molecular biology. 2012.10; 422 (5): 617-634. ( PubMed , DOI )

  4. Irie K, Shimomura T, Fujiyoshi Y: The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate. Nature communications. 2012.04; 3 793. ( PubMed , DOI )

  1. Rico F, Oshima A, Hinterdorfer P, Fujiyoshi Y, Scheuring S: Two-dimensional kinetics of inter-connexin interactions from single-molecule force spectroscopy. Journal of molecular biology. 2011.09; 412 (1): 72-79. ( PubMed , DOI )

  2. Goda M, Ohata M, Ikoma H, Fujiyoshi Y, Sugimoto M, Fujii R: Integumental reddish-violet coloration owing to novel dichromatic chromatophores in the teleost fish, Pseudochromis diadema. Pigment cell & melanoma research. 2011.08; 24 (4): 614-617. ( PubMed , DOI )

  3. Ohta Y, Nishikawa K, Hiroaki Y, Fujiyoshi Y: Electron tomographic analysis of gap junctions in lateral giant fibers of crayfish. Journal of structural biology. 2011.07; 175 (1): 49-61. ( PubMed , DOI )

  4. Wakao S, Kitada M, Kuroda Y, Shigemoto T, Matsuse D, Akashi H, Tanimura Y, Tsuchiyama K, Kikuchi T, Goda M, Nakahata T, Fujiyoshi Y, Dezawa M: Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 2011.06; 108 (24): 9875-9880. ( PubMed , DOI )

  5. Yakata K, Tani K, Fujiyoshi Y: Water permeability and characterization of aquaporin-11. Journal of structural biology. 2011.05; 174 (2): 315-320. ( PubMed , DOI )

  6. Fujiyoshi Y: Structural physiology based on electron crystallography. Protein science : a publication of the Protein Society. 2011.05; 20 (5): 806-817. ( PubMed , DOI )

  7. Shimomura T, Irie K, Nagura H, Imai T, Fujiyoshi Y: Arrangement and mobility of the voltage sensor domain in prokaryotic voltage-gated sodium channels. The Journal of biological chemistry. 2011.03; 286 (9): 7409-7417. ( PubMed , DOI )

  8. Abe K, Tani K, Fujiyoshi Y: Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant. Nature communications. 2011.01; 2 155. ( PubMed , DOI )

  9. Oshima A, Tani K, Toloue MM, Hiroaki Y, Smock A, Inukai S, Cone A, Nicholson BJ, Sosinsky GE, Fujiyoshi Y: Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels. Journal of molecular biology. 2011.01; 405 (3): 724-735. ( PubMed , DOI )

  10. Fujiyoshi Y: Electron crystallography for structural and functional studies of membrane proteins. Journal of electron microscopy. 2011; 60 Suppl 1 S149-59. ( PubMed , DOI )

  1. Mitsuma T, Tani K, Hiroaki Y, Kamegawa A, Suzuki H, Hibino H, Kurachi Y, Fujiyoshi Y: Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation. Journal of molecular biology. 2010.10; 402 (4): 669-681. ( PubMed , DOI )

  2. Matsuse D, Kitada M, Kohama M, Nishikawa K, Makinoshima H, Wakao S, Fujiyoshi Y, Heike T, Nakahata T, Akutsu H, Umezawa A, Harigae H, Kira J, Dezawa M: Human umbilical cord-derived mesenchymal stromal cells differentiate into functional Schwann cells that sustain peripheral nerve regeneration. Journal of neuropathology and experimental neurology. 2010.09; 69 (9): 973-985. ( PubMed , DOI )

  3. Nagura H, Irie K, Imai T, Shimomura T, Hige T, Fujiyoshi Y: Evidence for lateral mobility of voltage sensors in prokaryotic voltage-gated sodium channels. Biochemical and biophysical research communications. 2010.08; 399 (3): 341-346. ( PubMed , DOI )

  4. Kuroda Y, Kitada M, Wakao S, Nishikawa K, Tanimura Y, Makinoshima H, Goda M, Akashi H, Inutsuka A, Niwa A, Shigemoto T, Nabeshima Y, Nakahata T, Nabeshima Y, Fujiyoshi Y, Dezawa M: Unique multipotent cells in adult human mesenchymal cell populations. Proceedings of the National Academy of Sciences of the United States of America. 2010.05; 107 (19): 8639-8643. ( PubMed , DOI )

  5. Abe K, Tani K, Fujiyoshi Y: Structural and functional characterization of H+, K+-ATPase with bound fluorinated phosphate analogs. Journal of structural biology. 2010.04; 170 (1): 60-68. ( PubMed , DOI )

  6. Irie K, Kitagawa K, Nagura H, Imai T, Shimomura T, Fujiyoshi Y: Comparative study of the gating motif and C-type inactivation in prokaryotic voltage-gated sodium channels. The Journal of biological chemistry. 2010.02; 285 (6): 3685-3694. ( PubMed , DOI )

  7. Abe K, Tani K, Nishizawa T, Fujiyoshi Y: [Novel ratchet mechanism of gastric H(+), K(+)-ATPase revealed by electron crystallography of two-dimensional crystals]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2010.02; 130 (2): 205-210. ( PubMed , DOI )

  8. Schenk AD, Hite RK, Engel A, Fujiyoshi Y, Walz T: Electron crystallography and aquaporins. Methods in enzymology. 2010; 483 91-119. ( PubMed , DOI )

  1. Inutsuka A, Goda M, Fujiyoshi Y: Calyculin A-induced neurite retraction is critically dependent on actomyosin activation but not on polymerization state of microtubules. Biochemical and biophysical research communications. 2009.12; 390 (4): 1160-1166. ( PubMed , DOI )

  2. Noma K, Kimura K, Minatohara K, Nakashima H, Nagao Y, Mizoguchi A, Fujiyoshi Y: Triple N-glycosylation in the long S5-P loop regulates the activation and trafficking of the Kv12.2 potassium channel. The Journal of biological chemistry. 2009.11; 284 (48): 33139-33150. ( PubMed , DOI )

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