医化学分野

64  件  
※ 登録方法の違いにより重複して表示されている場合があります。

  1. Miyata Y, Segawa K: Protocol to analyze lipid asymmetry in the plasma membrane. STAR protocols. 2022.12; 3 (4): 101870. ( PubMed , DOI )

  2. Ochiai Y, Suzuki C, Segawa K, Uchiyama Y, Nagata S: Inefficient development of syncytiotrophoblasts in the Atp11a-deficient mouse placenta. Proceedings of the National Academy of Sciences of the United States of America. 2022.05; 119 (18): e2200582119. ( PubMed , DOI )

  3. Miyata Yugo, Tokumoto Shoko, Arai Tomohiko, Shaikhutdinov Nurislam, Deviatiiarov Ruslan, Fuse Hiroto, Gogoleva Natalia, Garushyants Sofya, Cherkasov Alexander, Ryabova Alina, Gazizova Guzel, Cornette Richard, Shagimardanova Elena, Gusev Oleg, Kikawada Takahiro: Identification of Genomic Safe Harbors in the Anhydrobiotic Cell Line, Pv11 GENES. 2022.03; 13 (3): ( PubMed , DOI )

  4. High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance 2022.03; 4 (2): ( DOI )

  1. Cas9-mediated genome editing reveals a significant contribution of calcium signaling pathways to anhydrobiosis in Pv11 cells 2021.12; 11 (1): ( DOI )

  2. Genome-Wide Role of HSF1 in Transcriptional Regulation of Desiccation Tolerance in the Anhydrobiotic Cell Line, Pv11. 2021.05; 22 (11): ( PubMed , DOI )

  1. Hanayo Nakanishi, Tomohiro Nishizawa, Katsumori Segawa, Osamu Nureki, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe: Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep. 2020.09; 32 (13): 108208. ( PubMed , DOI )

  2. Hanayo Nakanishi, Katsumasa Irie, Katsumori Segawa, Kazuya Hasegawa, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe: Crystal structure of a human plasma membrane phospholipid flippase. J Biol Chem. 2020.07; 295 (30): 10180-10194. ( PubMed , DOI )

  1. The Physiological Functions of a Model Peptide of G3LEA in Living Cells 2019; ( DOI )

  1. Establishment of gene transfer and gene silencing methods in a desiccation-tolerant cell line, Pv11 2017; 21 (1): 65-72. ( PubMed , DOI )

  1. Katsumori Segawa, Sachiko Kurata, Shigekazu Nagata: Human Type IV P-type ATPases That Work as Plasma Membrane Phospholipid Flippases and Their Regulation by Caspase and Calcium. J Biol Chem. 2016.01; 291 (2): 762-772. ( PubMed , DOI )

  1. Katsumori Segawa, Shigekazu Nagata: An Apoptotic 'Eat Me' Signal: Phosphatidylserine Exposure. Trends Cell Biol. 2015.11; 25 (11): 639-650. ( PubMed , DOI )

  2. Satoshi Toda, Chihiro Nishi, Yuichi Yanagihashi, Katsumori Segawa, Shigekazu Nagata: Clearance of Apoptotic Cells and Pyrenocytes. Curr Top Dev Biol. 2015; 114 267-295. ( PubMed , DOI )

  1. Hiroyuki Takatsu, Gaku Tanaka, Katsumori Segawa, Jun Suzuki, Shigekazu Nagata, Kazuhisa Nakayama, Hye-Won Shin: Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane. J Biol Chem. 2014.11; 289 (48): 33543-33556. ( PubMed , DOI )

  2. Katsumori Segawa, Sachiko Kurata, Yuichi Yanagihashi, Thijn R Brummelkamp, Fumihiko Matsuda, Shigekazu Nagata: Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure. Science. 2014.06; 344 (6188): 1164-1168. ( PubMed , DOI )

  3. Satoshi Toda, Katsumori Segawa, Shigekazu Nagata: MerTK-mediated engulfment of pyrenocytes by central macrophages in erythroblastic islands. Blood. 2014.06; 123 (25): 3963-3971. ( PubMed , DOI )

  4. Chihiro Nishi, Satoshi Toda, Katsumori Segawa, Shigekazu Nagata: Tim4- and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages. Mol Cell Biol. 2014.04; 34 (8): 1512-1520. ( PubMed , DOI )

  5. Katsumori Segawa, Jun Suzuki, Shigekazu Nagata: Flippases and scramblases in the plasma membrane. Cell Cycle. 2014; 13 (19): 2990-2991. ( PubMed , DOI )

  1. Masanori Miyanishi, Katsumori Segawa, Shigekazu Nagata: Synergistic effect of Tim4 and MFG-E8 null mutations on the development of autoimmunity. Int Immunol. 2012.09; 24 (9): 551-559. ( PubMed , DOI )

  1. Katsumori Segawa, Jun Suzuki, Shigekazu Nagata: Constitutive exposure of phosphatidylserine on viable cells. Proc Natl Acad Sci U S A. 2011.11; 108 (48): 19246-19251. ( PubMed , DOI )

  1. Katsumori Segawa, Morihiro Matsuda, Atsunori Fukuhara, Kentaro Morita, Yosuke Okuno, Ryutaro Komuro, Iichiro Shimomura: Identification of a novel distal enhancer in human adiponectin gene. J Endocrinol. 2009.01; 200 (1): 107-116. ( PubMed , DOI )

  1. Maiko Nozaki, Atsunori Fukuhara, Katsumori Segawa, Yosuke Okuno, Manabu Abe, Naomi Hosogai, Morihiro Matsuda, Ryutaro Komuro, Iichiro Shimomura: Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2007.12; 364 (1): 33-39. ( PubMed , DOI )

  2. Masaki Tanaka, Maiko Nozaki, Atsunori Fukuhara, Katsumori Segawa, Naohito Aoki, Morihiro Matsuda, Ryutaro Komuro, Iichiro Shimomura: Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway. Biochem Biophys Res Commun. 2007.07; 359 (2): 194-201. ( PubMed , DOI )

  3. Naomi Hosogai, Atsunori Fukuhara, Kazuya Oshima, Yugo Miyata, Sachiyo Tanaka, Katsumori Segawa, Shigetada Furukawa, Yoshihiro Tochino, Ryutaro Komuro, Morihiro Matsuda, Iichiro Shimomura: Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes. 2007.04; 56 (4): 901-911. ( PubMed , DOI )

  1. Katsumori Segawa, Atsunori Fukuhara, Naomi Hosogai, Kentaro Morita, Yosuke Okuno, Masaki Tanaka, Yasuhiko Nakagawa, Shinji Kihara, Tohru Funahashi, Ryutaro Komuro, Morihiro Matsuda, Iichiro Shimomura: Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism. Biochem Biophys Res Commun. 2006.10; 349 (3): 875-882. ( PubMed , DOI )

  1. 宮田 佑吾, 瀬川 勝盛: 細胞膜リン脂質の非対称性と脆弱性 Cytometry Research. 2023.04; 32 (2): 11-16. ( 医中誌 )

  1. Miyata Yugo, Yamada Kyoko, Nagata Shigekazu, Segawa Katsumori: Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes JOURNAL OF BIOLOGICAL CHEMISTRY. 2022.11; 298 (11): 102527. ( PubMed , DOI )

  2. 瀬川 勝盛, 宮田 佑吾: 【細胞死のすべて-そのメカニズムと,生命現象・疾患との関わり】アポトーシスと非アポトーシス細胞死　カスパーゼによるアポトーシスの実行 医学のあゆみ. 2022.10; 283 (5): 329-334. ( 医中誌 )

  3. 瀬川 勝盛: リン脂質フリッパーゼとヒト遺伝性疾患 臨床免疫・アレルギー科. 2022.08; 78 (2): 238-244. ( 医中誌 )

  4. 瀬川 勝盛: マクロファージ研究の新展開 細胞膜リン脂質の非対称性と脆弱性 Cytometry Research. 2022.05; 32 (Suppl.): 20. ( 医中誌 )

  5. Kondratyeva Sabina A., Voronina Taisiya A., Nesmelov Alexander A., Miyata Yugo, Tokumoto Shoko, Cornette Richard, Vorontsova Maria V., Kikawada Takahiro, Gusev Oleg A., Shagimardanova Elena I: Intracellular Localization and Gene Expression Analysis Provides New Insights on LEA Proteins' Diversity in Anhydrobiotic Cell Line BIOLOGY-BASEL. 2022.04; 11 (4): ( DOI )

  6. Ryoden Yuta, Segawa Katsumori, Nagata Shigekazu: Requirement of Xk and Vps13a for the P2X7-mediated phospholipid scrambling and cell lysis in mouse T cells PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022.02; 119 (7): ( PubMed , DOI )

  1. 瀬川 勝盛: 【新規細胞死機構が制御する生体応答】ホスファチジルセリンと死細胞の認識 細胞. 2021.10; 53 (12): 755-758. ( 医中誌 )

  2. Segawa Katsumori, Kikuchi Atsuo, Noji Tomoyasu, Sugiura Yuki, Hiraga Keita, Suzuki Chigure, Haginoya Kazuhiro, Kobayashi Yasuko, Matsunaga Mitsuhiro, Ochiai Yuki, Yamada Kyoko, Nishimura Takuo, Iwasawa Shinya, Shoji Wataru, Sugihara Fuminori, Nishino Kohei, Kosako Hidetaka, Ikawa Masahito, Uchiyama Yasuo, Suematsu Makoto, Ishikita Hiroshi, Kure Shigeo, Nagata Shigekazu: A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes JOURNAL OF CLINICAL INVESTIGATION. 2021.09; 131 (18): ( PubMed , DOI )

  3. Nagata Shigekazu, Segawa Katsumori: Sensing and clearance of apoptotic cells. CURRENT OPINION IN IMMUNOLOGY. 2021.02; 68 1-8. ( PubMed , DOI )

  1. 中西 華代, 入江 克雅, 瀬川 勝盛, 長田 重一, 長谷川 和也, 藤吉 好則, 阿部 一啓: ヒト細胞膜フリッパーゼATP11CのX線結晶構造解析 日本生化学会大会プログラム・講演要旨集. 2020.09; 93回 [P-132]. ( 医中誌 )

  2. Ryoden Yuta, Fujii Toshihiro, Segawa Katsumori, Nagata Shigekazu: Functional Expression of the P2X7 ATP Receptor Requires Eros JOURNAL OF IMMUNOLOGY. 2020.02; 204 (3): 559-568. ( PubMed , DOI )

  3. Nagata Shigekazu, Sakuragi Takaharu, Segawa Katsumori: Flippase and scramblase for phosphatidylserine exposure CURRENT OPINION IN IMMUNOLOGY. 2020.02; 62 31-38. ( PubMed , DOI )

  4. 徳本 翔子, 宮田 佑吾, 黄川田 隆洋: 乾眠できる昆虫ネムリユスリカの放射線耐性 放射線生物研究. 2020.01; 54 (4): 225-236. ( 医中誌 )

  1. 瀬川 勝盛: ホスファチジルセリンの移層と死細胞の認識機構 生化学. 2019.12; 91 (6): 743-752. ( 医中誌 )

  2. 瀬川 勝盛: ホスファチジルセリンの移層と死細胞の認識機構 生化学. 2019.12; 91 (6): 743-752. ( 医中誌 )

  3. 瀬川 勝盛, 長田 重一: リン脂質フリッパーゼとB細胞分化 臨床免疫・アレルギー科. 2019.07; 72 (1): 80-86. ( 医中誌 )

  4. Tsuji Takuma, Cheng Jinglei, Tatematsu Tsuyako, Ebata Aoi, Kamikawa Hiroki, Fujita Akikazu, Gyobu Sayuri, Segawa Katsumori, Arai Hiroyuki, Taguchi Tomohiko, Nagata Shigekazu, Fujimoto Toyoshi: Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019.07; 116 (27): 13368-13373. ( PubMed , DOI )

  5. 瀬川 勝盛, 長田 重一: リン脂質フリッパーゼとB細胞分化 臨床免疫・アレルギー科. 2019.07; 72 (1): 80-86. ( 医中誌 )

  6. Nishi Chihiro, Yanagihashi Yuichi, Segawa Katsumori, Nagata Shigekazu: MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation JOURNAL OF BIOLOGICAL CHEMISTRY. 2019.05; 294 (18): 7221-7230. ( PubMed , DOI )

  1. Segawa Katsumori, Yanagihashi Yuichi, Yamada Kyoko, Suzuki Chigure, Uchiyama Yasuo, Nagata Shigekazu: Phospholipid flippases enable precursor B cells to flee engulfment by macrophages PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018.11; 115 (48): 12212-12217. ( PubMed , DOI )

  2. 瀬川 勝盛, 長田 重一: 細胞膜リン脂質動態の生理と病態 細胞膜リン脂質の非対称性とリン脂質フリッパーゼ 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [2S02m-02]. ( 医中誌 )

  3. 瀬川 勝盛, 鈴木 淳: 【脂質クオリティ　生命機能と健康を支える脂質の多様性】(第2章)リポクオリティの違いを生み出し識別する機構　フリッパーゼとスクランブラーゼによる細胞膜リン脂質の分布制御 実験医学. 2018.06; 36 (10): 1645-1651. ( 医中誌 )

  4. 瀬川 勝盛, 鈴木 淳: 【脂質クオリティ 生命機能と健康を支える脂質の多様性】(第2章)リポクオリティの違いを生み出し識別する機構 フリッパーゼとスクランブラーゼによる細胞膜リン脂質の分布制御 実験医学. 2018.06; 36 (10): 1645-1651. ( 医中誌 )

  5. Segawa Katsumori, Kurata Sachiko, Nagata Shigekazu: The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane JOURNAL OF BIOLOGICAL CHEMISTRY. 2018.02; 293 (6): 2172-2182. ( PubMed , DOI )

  1. 柳橋 祐一, 瀬川 勝盛, 長田 重一: 細胞死の多様性と死細胞からはじまる生体応答の解明 ホスファチジルセリン受容体Tim4によるTAMレセプター依存的貪食の促進 生命科学系学会合同年次大会. 2017.12; 2017年度 [3AW15-6]. ( 医中誌 )

  2. Yanagihashi Yuichi, Segawa Katsumori, Maeda Ryota, Nabeshima Yo-ichi, Nagata Shigekazu: Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017.08; 114 (33): 8800-8805. ( PubMed , DOI )

  3. Gyobu Sayuri, Ishihara Kenji, Suzuki Jun, Segawa Katsumori, Nagata Shigekazu: Characterization of the scrambling domain of the TMEM16 family PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017.06; 114 (24): 6274-6279. ( PubMed , DOI )

  1. 中西瑛太, CORNETTE Richard, 吉田祐貴, 新井智彦, 徳本翔子, 宮田佑吾, GUSEV Oleg, GUSEV Oleg, GUSEV Oleg, 黄川田隆洋, 黄川田隆洋: ゲノムから読み解く強酸耐性昆虫Polypedilum sp.cf.tamanigrumの強酸性環境への適応機構 日本分子生物学会年会プログラム・要旨集(Web). 2021; 44th

  1. Development of a Tet-On Inducible Expression System for the Anhydrobiotic Cell Line, Pv11 2020.11; 11 (11): 781. ( DOI )

  2. 布施寛人, 宮田佑吾, CORNETTE Richard, 黄川田隆洋, 黄川田隆洋: 灌流システムを用いたPv11細胞におけるリアルタイムCa2+イメージング手法の開発 低温生物工学会誌. 2020; 66 (2):

  3. 布施寛人, 宮田佑吾, コルネット リシャー, 黄川田隆洋, 黄川田隆洋: 灌流システムを用いたPv11細胞におけるリアルタイムCa2+イメージング手法の開発 低温生物工学会セミナー及び年会講演要旨集. 2020; 65th

  4. New group of transmembrane proteins associated with desiccation tolerance in the anhydrobiotic midge Polypedilum vanderplanki 2020; 10 (1): ( PubMed , DOI )

  1. Intracellular localization and gene expression analysis provide new insights on LEA proteins’ diversity in anhydrobiotic midge 2019.10; ( DOI )

  2. 布施寛人, 宮田佑吾, CORNETTE Richard, 黄川田隆洋, 黄川田隆洋: Pv11細胞の乾燥耐性誘導時におけるカルシウム濃度変化の検出 日本分子生物学会年会プログラム・要旨集(Web). 2019; 42nd

  3. 布施寛人, 宮田佑吾, CORNETTE Richard, 黄川田隆洋: Sf9細胞を用いた昆虫嗅覚受容体のリガンド探索手法の開発 日本農芸化学会大会講演要旨集(Web). 2019; 2019

  4. 布施寛人, 宮田佑吾, コルネット リシャー, 黄川田隆洋, 黄川田隆洋: カルシウムセンサータンパク質GCaMPを用いたPv11細胞の乾燥過程におけるカルシウム濃度変化検出系の構築 低温生物工学会セミナー及び年会講演要旨集. 2019; 64th

  5. Identification of a novel strong promoter from the anhydrobiotic midge, Polypedilum vanderplanki, with conserved function in various insect cell lines 2019; 9 (1): ( PubMed , DOI )

  1. Cooption of heat shock regulatory system for anhydrobiosis in the sleeping chironomid Polypedilum vanderplanki 2018; 115 (10): E2477-E2486. ( PubMed , DOI )

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