Personnel Information

写真a

MIYAMOTO Takaaki


Job title

Junior Associate Professor
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Graduating School 【 display / non-display 】

  • Okayama University, 2012.03, Graduated

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Graduate School 【 display / non-display 】

  • Okayama University, Master's Course, 2014.03, Completed

  • Nara Institute of Science and Technology, Doctor's Course, 2017.03, Completed

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Campus Career 【 display / non-display 】

  • 2025.02
    -
    Now
    Institute of Science Tokyo， -， Institute of Integrated Research， Division of Biomedical Materials， Soft Matter and Biomedical Engineering， Junior Associate Professor
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External Career 【 display / non-display 】

  • 2017.04
    -
    2022.03
    RIKEN, RIKEN Center for Sustainable Resource Science, Biomacromolecules Research Team, Postdoctoral researcher
  • 2020.10
    -
    2023.03
    JST-ERATO Numata Organellar Reaction Cluster Project, Fusion Peptide Utilization Group, Group Leader
  • 2022.04
    -
    2025.01
    RIKEN, RIKEN Center for Sustainable Resource Science, Biomacromolecules Research Team, Research Scientist
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Research Areas 【 display / non-display 】

  • Polymer chemistry

  • Bio chemistry

  • Nanobioscience

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Research Theme 【 display / non-display 】

  • Micelle complexes displaying multiple functional peptides for efficient DNA delivery to plant mitochondria, 2019.04 - 2022.03

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Published Papers & Misc 【 display / non-display 】

  1. Dual-function nanographene-peptide conjugates enable super-resolution mitochondria imaging and targeted DNA delivery in plants 2026.02; 247 120994. ( DOI )

  2. Miyamoto, T; Morey-Yagi, SR; Numata, K. A Chimeric Peptide for Shielding Plant Photosynthetic Systems against Excess Light Stress via Chloroplast-Targeted ROS Quenching JACS AU. 2024.10; 4 (12): 4691-4699. ( PubMed, DOI )

  3. Yoshinaga, N; Miyamoto, T; Goto, M; Tanaka, A; Numata, K. Phenylboronic Acid-Functionalized Micelles Dual-Targeting Boronic Acid Transporter and Polysaccharides for siRNA Delivery into Brown Algae JACS AU. 2024.03; 4 (4): 1385-1395. ( PubMed, DOI )

  4. Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous Multiple Gene Expression 2023.11; ( DOI )

  5. Advancing Biomolecule Delivery in Plants: Harnessing Synthetic Nanocarriers to Overcome Multiscale Barriers for Cutting-Edge Plant Bioengineering 2023.09; 96 (9): 1026-1044. ( DOI )

  6. Abe, N; Fujita, S; Miyamoto, T; Tsuchiya, K; Numata, K. Plant Mitochondrial-Targeted Gene Delivery by Peptide/DNA Micelles Quantitatively Surface-Modified with Mitochondrial Targeting and Membrane-Penetrating Peptides. BIOMACROMOLECULES. 2023.06; 24 (8): 3657-3665. ( PubMed, DOI )

  7. Law, SSY; Miyamoto, T; Numata, K. Organelle-targeted gene delivery in plants by nanomaterials CHEMICAL COMMUNICATIONS. 2023; 59 (47): 7166-7181. ( PubMed, DOI )

  8. Miyamoto, T; Tsuchiya, K; Toyooka, K; Goto, Y; Tateishi, A; Numata, K. Relaxation of the Plant Cell Wall Barrier via Zwitterionic Liquid Pretreatment for Micelle-Complex-Mediated DNA Delivery to Specific Plant Organelles. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2022.08; 61 (32): e202204234. ( PubMed, DOI )

  9. Miyamoto, T; Toyooka, K; Chuah, JA; Odahara, M; Higchi-Takeuchi, M; Goto, Y; Motoda, Y; Kigawa, T; Kodama, Y; Numata, K. A Synthetic Multidomain Peptide That Drives a Macropinocytosis-Like Mechanism for Cytosolic Transport of Exogenous Proteins into Plants JACS AU. 2022.01; 2 (1): 223-233. ( PubMed, DOI )

  10. Watanabe, K; Odahara, M; Miyamoto, T; Numata, K. Fusion Peptide-Based Biomacromolecule Delivery System for Plant Cells. ACS BIOMATERIALS SCIENCE & ENGINEERING. 2021.06; 7 (6): 2246-2254. ( PubMed, DOI )

  11. Miyamoto, T; Tsuchiya, K; Numata, K. Endosome-escaping micelle complexes dually equipped with cell-penetrating and endosome-disrupting peptides for efficient DNA delivery into intact plants. NANOSCALE. 2021.03; 13 (11): 5679-5692. ( PubMed, DOI )

  12. Higuchi-Takeuchi, M; Miyamoto, T; Foong, CP; Goto, M; Morisaki, K; Numata, K. Peptide-Mediated Gene Transfer into Marine Purple Photosynthetic Bacteria. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020.11; 21 (22): ( PubMed, DOI )

  13. Miyamoto, T; Tsuchiya, K; Numata, K. Dual Peptide-Based Gene Delivery System for the Efficient Transfection of Plant Callus Cells BIOMACROMOLECULES. 2020.05; 21 (7): 2735-2744. ( PubMed, DOI )

  14. Tsuchiya, K; Yilmaz, N; Miyamoto, T; Masunaga, H; Numata, K. Zwitterionic Polypeptides: Chemoenzymatic Synthesis and Loosening Function for Cellulose Crystals. BIOMACROMOLECULES. 2020.05; 21 (5): 1785-1794. ( PubMed, DOI )

  15. Miyamoto, T; Hayashi, Y; Yoshida, K; Watanabe, H; Uchihashi, T; Yonezawa, K; Shimizu, N; Kamikubo, H; Hirota, S. Construction of a Quadrangular Tetramer and a Cage-Like Hexamer from Three-Helix Bundle-Linked Fusion Proteins. ACS SYNTHETIC BIOLOGY. 2019.05; 8 (5): 1112-1120. ( PubMed, DOI )

  16. Kousuke Tsuchiya, Yu Miyagi, Takaaki Miyamoto, Prashant G. Gudeangadi, Keiji Numata. Synthesis of Polypeptides (Chapter 8) Enzymatic Polymerization towards Green Polymer Chemistry. 2019; 233-265.

  17. Enhanced stability of Cu2+-ATCUN complexes under physiologically relevant conditions by insertion of structurally bulky and hydrophobic amino acid residues into the ATCUN motif 2016.06; 45 (23): 9436-9445. ( PubMed, DOI )

  18. Domain-swapped cytochrome cb(562) dimer and its nanocage encapsulating a Zn-SO4 cluster in the internal cavity 2015; 6 (12): 7336-7342. ( DOI )

  19. Basicity of N-Terminal Amine in ATCUN Peptide Regulates Stability Constant of Albumin-like Cu2+ Complex 2013.09; 42 (9): 1099-1101. ( DOI )

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Awards & Honors 【 display / non-display 】

  • RIKEN CSRS Incentive Award，RIKEN，2023.04

  • Protein Society Young Investigator Travel Award，The 30th Annual Symposium of the Protein Society，2016.07

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