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CHENG LIHONG(チェン リーホン) CHENG LIHONG
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出身学校 【 表示 / 非表示 】
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河南大学(Henan University) 薬学部(School of Pharmacy) 薬学(Phamacy) 2014年06月 卒業
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浙江大学(Zhengjiang University) 薬学部(College of Pharmaceutical Sciences) 薬物化学(Medicinal chemistry) 2019年06月 卒業
出身大学院 【 表示 / 非表示 】
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浙江大学(Zhejiang University) 薬学院(College of Pharmaceutical Sciences) 薬物化学(Medicinal chemistry) 博士課程 2019年06月 修了
経歴(学外) 【 表示 / 非表示 】
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2019年07月-2021年07月浙江大学 薬学部(College of Pharmacetical Sciences) 特任研究員
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2021年11月-2023年11月九州大学 農学部 特任研究員
研究テーマ 【 表示 / 非表示 】
競争的資金等の研究課題 【 表示 / 非表示 】
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Study on the mechanism of rapid change of mitochondrial shape and distribution induced by C-RAF using optogenetics tools and live imaging
文部科学省/日本学術振興会 : 2024年 - 2025年
論文・総説 【 表示 / 非表示 】
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Lihong Cheng, Caiyue Shi, Xixi Li, Toshiro Matsui. Impact of Peptide Transport and Memory Function in the Brain Nutrients. 2024.09; ( DOI )
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Cheng L, Shi C, Nakamura S, Esaki N, Ichiba Y, Tanaka M, Sakai K, Matsui T. Adiponectin-Receptor Agonistic Dipeptide Tyr-Pro Stimulates the Acetylcholine Nervous System in NE-4C Cells. Journal of agricultural and food chemistry. 2024.04; 72 (13): 7121-7129. ( PubMed, DOI )
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Cheng L, Tanaka M, Yoshino A, Nagasato Y, Takata F, Dohgu S, Matsui T. A memory-improving dipeptide, Tyr-Pro, can reach the mouse brain after oral administration. Scientific reports. 2023.10; 13 (1): 16908. ( PubMed, DOI )
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Xiang, L; Wu, QB; Cheng, LH; Sun, KY; Li, J; Yoshida, M; Qi, JH. Leptin and Adiponectin Signaling Pathways Are Involved in the Antiobesity Effects of Peanut Skin Extract OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019.10; 2019 1-14. ( PubMed, DOI )
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Bian, LL; Cao, SN; Cheng, LH; Nakazaki, A; Nishikawa, T; Qi, JH. Semi-synthesis and Structure-Activity Relationship of Neuritogenic Oleanene Derivatives CHEMMEDCHEM. 2018.09; 13 (18): 1972-1977. ( PubMed, DOI )
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Qi, JH; Cheng, LH; Sun, YJ; Hirata, Y; Ushida, N; Ma, ZH; Osada, H; Nishikawa, T; Xiang, L. Identification of an Asexual Reproduction Inducer of Phytopathogenic and Toxigenic <i>Fusarium</i> ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2018.07; 57 (27): 8100-8104. ( PubMed, DOI )
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Zhang, H; Farooq, U; Cheng, LH; Ye, Y; Wang, YC; Kawagishi, H; Ojika, M; Qi, JH. Specific Inhibitors of Sporangium Formation of <i>Phytophthora capsici</i> from <i>Kalimeris indica</i> CHEMISTRY OF NATURAL COMPOUNDS. 2018.05; 54 (3): 567-569. ( DOI )
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Cheng, LH; Wang, YH; Xiang, L; Qi, JH. Heat Shock Cognate 70 kDa Protein Is the Target of Tetradecyl 2,3-Dihydroxybenzoate for Neuritogenic Effect in PC12 Cells BIOMEDICINES. 2021.10; 9 (10): 1483. ( PubMed, DOI )
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Cheng, LH; Osada, H; Xing, TY; Yoshida, M; Xiang, L; Qi, JH. The Insulin Receptor: A Potential Target of Amarogentin Isolated from <i>Gentiana rigescens</i> Franch That Induces Neurogenesis in PC12 Cells BIOMEDICINES. 2021.05; 9 (5): ( PubMed, DOI )
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Pan, YJ; Liu, YN; Fujii, R; Farooq, U; Cheng, LH; Matsuura, A; Qi, JH; Xiang, L. Ehretiquinone from <i>Onosma bracteatum</i> Wall Exhibits Antiaging Effect on Yeasts and Mammals through Antioxidative Stress and Autophagy Induction OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2021.01; 2021 1-15. ( PubMed, DOI )
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Disasa, D; Cheng, LH; Manzoor, M; Liu, Q; Wang, Y; Xiang, L; Qi, JH. Amarogentin from <i>Gentiana rigescens</i> Franch Exhibits Antiaging and Neuroprotective Effects through Antioxidative Stress OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020.08; 2020 1-15. ( PubMed, DOI )
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Liu, Q; Cheng, LH; Matsuura, A; Xiang, L; Qi, JH. Gentiopicroside, a Secoiridoid Glycoside from <i>Gentiana rigescens</i> Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020.08; 2020 1-12. ( PubMed, DOI )
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Cheng, LH; Muroi, M; Cao, SN; Bian, LL; Osada, H; Xiang, L; Qi, JH. 3β,23,28-Trihydroxy-12-oleanene 3β-Caffeate from <i>Desmodium sambuense</i>-Induced Neurogenesis in PC12 Cells Mediated by ER Stress and BDNF-TrkB Signaling Pathways MOLECULAR PHARMACEUTICS. 2019.04; 16 (4): 1423-1432. ( PubMed, DOI )
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Cheng, LH; Ye, Y; Xiang, L; Osada, H; Qi, JH. Lindersin B from <i>Lindernia crustacea</i> induces neuritogenesis by activation of tyrosine kinase A/phosphatidylinositol 3 kinase/extracellular signal-regulated kinase signaling pathway PHYTOMEDICINE. 2017.01; 24 31-38. ( PubMed, DOI )
講演・口頭発表等 【 表示 / 非表示 】
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Lihong Cheng. Bioavailability and mechanism of action of blood brain barrier transportable dipeptide Tyr-Pro for its therapeutic potential on cognitive impairment. 日本食品科学工学会第71回大会 2024.08.30 名古屋
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Lihong Cheng, Atsuko Yoshino, Yuki Nagasato, Fuyuko Takata, Shinya Dohgu, Mitsuru Tanaka, Toshiro Matsui. Tyr-Pro, a dipeptide with anti-cognitive impairment effect, can enter into mouse brain after oral intake. 日本食品科学工学会第70回記念大会 2023.08.25
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Lihong Cheng, Atsuko Yoshino, Yuki Nagasato, Fuyuko Takata, Shinya Dohgu, Mitsuru Tanaka, Toshiro Matsui. Oral intake of anti-cognitive impairment dipeptide, Tyr-Pro, leads to its intact accumulation in mouse brain. 第77回日本栄養・食糧学会大会 2023.05.13
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Cheng Lihong, 芳野 温子, 永里 侑貴, 高田 芙友子, 道具 伸也, 田中 充, 松井 利郎. 抗認知障害ジペプチドTyr-Proの経口摂取によるマウス脳への蓄積(Oral intake of anti-cognitive impairment dipeptide, Tyr-Pro, leads to its intact accumulation in mouse brain). 日本栄養・食糧学会大会講演要旨集 2023.03.01
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Lihong Cheng, Atsuko Yoshino, Yuki Nagasato, Fuyuko Takata, Shinya Dohgu, Mitsuru Tanaka, Toshiro Matsui. Evidence on a brain transport of anti-cognitive dipeptide, Tyr-Pro, after oral administration to mice. 22nd IUNS-ICN International Congress of Nutrition 2022.12.08
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Lihong Cheng, Ying Ye, Lan Xiang, Hiroyuki Osada, Jianhua Qi. A neuritogenic triterpenoid from Lindernia crustacea and its mechanism of action. Joint Symposium on Integrated Biosciences between Zhejiang University and The University of Tokyo 2017.12.01
受賞学術賞 【 表示 / 非表示 】
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優秀ポスター賞(国際ポスタープレゼンテーショングループ),日本食品科学工学会,2023年08月
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JSPS外国人特別研究員(スタンダード),日本学術振興会,2021年11月