Personnel Information

写真a

CHENG LIHONG


Job title

Assistant Professor

Birth date

1993

Laboratory Phone number

+81-03-5803-5143

Mail Address

The inquiry by e-mail is 《here》

Homepage URL

https://researchmap.jp/clh1104?lang=ja

Research Areas, Keywords

Cell biology, molecular biology, food analysis, natural medicinal chemistry

Profile

2024.4-present, Tokyo Medical and Dental University, assistant professor;
2021.11-2023.11, Kyushu University, JSPS postdoctoral;
2019.7-2021.7, Zhejiang University, Postdoctoral;
2014.6-2019.6, Zhejiang University, Ph.D.;
2010.6-2014.6, Henan University, B.S.;

Field Introduction URL

Department of Cell Biology

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Graduating School 【 display / non-display 】

  • Henan University, School of Pharmacy, Phamacy, 2014.06, Graduated

  • Zhengjiang University, College of Pharmaceutical Sciences, Medicinal chemistry, 2019.06, Graduated

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Graduate School 【 display / non-display 】

  • Zhejiang University, College of Pharmaceutical Sciences, Medicinal chemistry, Doctor's Course, 2019.06, Completed

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Campus Career 【 display / non-display 】

  • 2024.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Biology， Assistant Professor
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External Career 【 display / non-display 】

  • 2019.07
    -
    2021.07
    Zhejiang Univeristy, College of Pharmacetical Sciences, Project Researcher
  • 2021.11
    -
    2023.11
    Kyushu University, School of Agriculture, Project Researcher
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Research Areas 【 display / non-display 】

  • Food sciences

  • Pharmaceutical chemistry and drug development sciences

  • Molecular biology

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Research Theme 【 display / non-display 】

  • Study on the mechanism of rapid change of mitochondrial shape and distributi on induced by C-RAF using optogenetics tools and live imaging, 2024.04 - Now

  • Study on food factors preventing dementia pathogenesis, 2021.11 - 2023.11

  • Chemical and biological studies of compounds with NGF-mimic activity from natural products, 2014.06 - 2021.06

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Published Papers & Misc 【 display / non-display 】

  1. Lihong Cheng, Caiyue Shi, Xixi Li, Toshiro Matsui. Impact of Peptide Transport and Memory Function in the Brain Nutrients. 2024.09; ( DOI )

  2. Cheng L, Shi C, Nakamura S, Esaki N, Ichiba Y, Tanaka M, Sakai K, Matsui T. Adiponectin-Receptor Agonistic Dipeptide Tyr-Pro Stimulates the Acetylcholine Nervous System in NE-4C Cells. Journal of agricultural and food chemistry. 2024.04; 72 (13): 7121-7129. ( PubMed, DOI )

  3. Cheng L, Tanaka M, Yoshino A, Nagasato Y, Takata F, Dohgu S, Matsui T. A memory-improving dipeptide, Tyr-Pro, can reach the mouse brain after oral administration. Scientific reports. 2023.10; 13 (1): 16908. ( PubMed, DOI )

  4. Xiang, L; Wu, QB; Cheng, LH; Sun, KY; Li, J; Yoshida, M; Qi, JH. Leptin and Adiponectin Signaling Pathways Are Involved in the Antiobesity Effects of Peanut Skin Extract OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019.10; 2019 1-14. ( PubMed, DOI )

  5. Bian, LL; Cao, SN; Cheng, LH; Nakazaki, A; Nishikawa, T; Qi, JH. Semi-synthesis and Structure-Activity Relationship of Neuritogenic Oleanene Derivatives CHEMMEDCHEM. 2018.09; 13 (18): 1972-1977. ( PubMed, DOI )

  6. Qi, JH; Cheng, LH; Sun, YJ; Hirata, Y; Ushida, N; Ma, ZH; Osada, H; Nishikawa, T; Xiang, L. Identification of an Asexual Reproduction Inducer of Phytopathogenic and Toxigenic <i>Fusarium</i> ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2018.07; 57 (27): 8100-8104. ( PubMed, DOI )

  7. Zhang, H; Farooq, U; Cheng, LH; Ye, Y; Wang, YC; Kawagishi, H; Ojika, M; Qi, JH. Specific Inhibitors of Sporangium Formation of <i>Phytophthora capsici</i> from <i>Kalimeris indica</i> CHEMISTRY OF NATURAL COMPOUNDS. 2018.05; 54 (3): 567-569. ( DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Lihong Cheng. Bioavailability and mechanism of action of blood brain barrier transportable dipeptide Tyr-Pro for its therapeutic potential on cognitive impairment. 日本食品科学工学会第71回大会 2024.08.30 名古屋

  2. Lihong Cheng, Atsuko Yoshino, Yuki Nagasato, Fuyuko Takata, Shinya Dohgu, Mitsuru Tanaka, Toshiro Matsui. Tyr-Pro, a dipeptide with anti-cognitive impairment effect, can enter into mouse brain after oral intake. 日本食品科学工学会第70回記念大会 2023.08.25

  3. Lihong Cheng, Atsuko Yoshino, Yuki Nagasato, Fuyuko Takata, Shinya Dohgu, Mitsuru Tanaka, Toshiro Matsui. Oral intake of anti-cognitive impairment dipeptide, Tyr-Pro, leads to its intact accumulation in mouse brain. 第77回日本栄養・食糧学会大会 2023.05.13

  4. Cheng Lihong, 芳野 温子, 永里 侑貴, 高田 芙友子, 道具 伸也, 田中 充, 松井 利郎. 抗認知障害ジペプチドTyr-Proの経口摂取によるマウス脳への蓄積(Oral intake of anti-cognitive impairment dipeptide, Tyr-Pro, leads to its intact accumulation in mouse brain). 日本栄養・食糧学会大会講演要旨集 2023.03.01

  5. Lihong Cheng, Atsuko Yoshino, Yuki Nagasato, Fuyuko Takata, Shinya Dohgu, Mitsuru Tanaka, Toshiro Matsui. Evidence on a brain transport of anti-cognitive dipeptide, Tyr-Pro, after oral administration to mice. 22nd IUNS-ICN International Congress of Nutrition 2022.12.08

  6. Lihong Cheng, Ying Ye, Lan Xiang, Hiroyuki Osada, Jianhua Qi. A neuritogenic triterpenoid from Lindernia crustacea and its mechanism of action. Joint Symposium on Integrated Biosciences between Zhejiang University and The University of Tokyo 2017.12.01

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Awards & Honors 【 display / non-display 】

  • Outstanding Poster Award，The Japanese Society for Food Science and Technology，2023.08

  • Postdoctoral Fellowships for Research in Japan，Japam Society for the promotion of Science，2021.11

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Campus class subject 【 display / non-display 】

  • Cell Biology，2024 - Now

  • Histology，2024 - Now

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