Personnel Information


BABA Minami

Job title

Assistant Professor

Research Areas, Keywords

Plasmodium, Parasitology, Toxoplasma, sporozoite, Liver infection

Field Introduction URL

東京医科歯科大学 医歯学総合研究科 寄生虫学・熱帯医学

Graduating School 【 display / non-display

  • Gifu University, 2013.03, Graduated

Graduate School 【 display / non-display

  • Gifu University, United Graduate School, Division of Veterinary Medicine, Veterinary Science, Doctor's Course, 2017.03, Completed

Campus Career 【 display / non-display

  • 2023.06
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Public Health, Department of Parasitology & Tropical Medicine, Assistant Professor

External Career 【 display / non-display

  • 2017.04
    Ehime University Proteo-Science Center, Department of Molecular Parasitology, Postdoctral researcher
  • 2021.06
    Nagasaki University, Institute of Tropical Medicine, Research Field of Microbiology, Department of Protozoology, Assistant Professor
  • 2023.06
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences Department of Parasitology and Tropical Medicine, Assistant Professor

Academic Society Affiliations 【 display / non-display



  • The Japanese Society of Veterinary Parasitologists (JSVP)

Research Areas 【 display / non-display

  • Parasitology

  • Molecular biology

  • Veterinary medical science


Research Theme 【 display / non-display

  • Investigation of the molecular mechanism of RON4 in Plasmodium berghei sporozoite infection of mammalian hosts, 2020.04 - 2024.03

  • Investigation of the mechanisms of RAMA on secretory protein trafficking in sporozoites, 2019.04 - 2022.03

  • Elucidation of the rule of Plasmodium parasite specific rhoptry protein in liver infection, 2018.04 - 2020.03

  • Elucidation of the mechanisms of RON3 during sporozoites invasion of hepatocytes, 2016.04 - 2019.03

Published Papers & Misc 【 display / non-display

  1. Baba Minami, Nozaki Mamoru, Tachibana Mayumi, Tsuboi Takafumi, Torii Motomi, Ishino Tomoko. Rhoptry neck protein 4 plays important roles during Plasmodium sporozoite infection of the mammalian liver MSPHERE. 2023.06; 8 (4): e0058722. ( PubMed, DOI )

  2. Huang Wei-Chiao, Mabrouk Moustafa T., Zhou Luwen, Baba Minami, Tachibana Mayumi, Torii Motomi, Takashima Eizo, Locke Emily, Plieskatt Jordan, King C. Richter, Coelho Camila H., Duffy Patrick E., Long Carole, Tsuboi Takafumi, Miura Kazutoyo, Wu Yimin, Ishino Tomoko, Lovell Jonathan F.. Vaccine co-display of CSP and Pfs230 on liposomes targeting two Plasmodium falciparum differentiation stages COMMUNICATIONS BIOLOGY. 2022.08; 5 (1): 773. ( PubMed, DOI )

  3. Tachibana Mayumi, Iriko Hideyuki, Baba Minami, Torii Motomi, Ishino Tomoko. PSOP1(Putative Secreted Ookinete Protein 1)はネズミマラリア原虫Plasmodium yoeliiとP.bergheiオーキネートのマイクロネームに局在化する(PSOP1, putative secreted ookinete protein 1, is localized to the micronemes of Plasmodium yoelii and P. berghei ookinetes) Parasitology International. 2021.10; 84 1-4. ( ichushi )

  4. PSOP1, putative secreted ookinete protein 1, is localized to the micronemes of Plasmodium yoelii and P. berghei ookinetes 2021.10; 84 102407. ( PubMed, DOI )

  5. Detection of the Rhoptry Neck Protein Complex in Plasmodium Sporozoites and Its Contribution to Sporozoite Invasion of Salivary Glands 2020.08; 5 (4): ( PubMed, DOI )

  6. The C-terminal region of the Plasmodium yoelii microgamete surface antigen PyMiGS induces potent anti-malarial transmission-blocking immunity in mice. 2020.03; ( PubMed, DOI )

  7. Observation of morphological changes of female osmiophilic bodies prior to Plasmodium gametocyte egress from erythrocytes. 2020.01; 236 111261. ( PubMed, DOI )

  8. Miura K, Tachibana M, Takashima E, Morita M, Kanoi BN, Nagaoka H, Baba M, Torii M, Ishino T, Tsuboi T. Malaria transmission-blocking vaccines: wheat germ cell-free technology can accelerate vaccine development. Expert review of vaccines. 2019.10; 18 (10): 1017-1027. ( PubMed, DOI )

  9. Expression and Localization Profiles of Rhoptry Proteins in Plasmodium berghei Sporozoites 2019.09; 9 ( PubMed, DOI )

  10. Rhoptry neck protein 11 has crucial roles during malaria parasite sporozoite invasion of salivary glands and hepatocytes. 2019.08; 49 (9): 725-735. ( PubMed, DOI )

  11. Rhoptry neck protein 2 expressed in Plasmodium sporozoites plays a crucial role during invasion of mosquito salivary glands 2019.01; 21 (1): e12964. ( PubMed, DOI )

  12. Aye KM, Nagayasu E, Baba M, Yoshida A, Takashima Y, Maruyama H. Evaluation of LIPS (luciferase immunoprecipitation system) for serodiagnosis of Toxoplasmosis. Journal of immunological methods. 2018.09; 462 91-100. ( PubMed, DOI )

  13. Baba Minami, Batanova Tatiana, Kitoh Katsuya, Takashima Yasuhiro. Adhesion of Toxoplasma gondii tachyzoite-infected vehicle leukocytes to capillary endothelial cells triggers timely parasite egression SCIENTIFIC REPORTS. 2017.07; 7 (1): 5675. ( PubMed, DOI )

  14. Baba Minami, Kitoh Katsuya, Takashima Yasuhiro. Removal of extracellular Toxoplasma gondii tachyzoites from suspended cell culture PARASITOLOGY INTERNATIONAL. 2016.10; 65 (5): 536-538. ( DOI )

  15. Ali Md. Wajed, Alauddin Md., Azad Md. Thoufic Anam, Hasan Md. Ariful, Appiah-Kwarteng Cornelia, Takasu Masaki, Baba Minami, Kitoh Katsuya, Rahman Moizur, Takashima Yasuhiro. Theileria annulata seroprevalence among different cattle breeds in Rajshahi Division, Bangladesh JOURNAL OF VETERINARY MEDICAL SCIENCE. 2016.10; 78 (10): 1577-1582. ( DOI )

  16. Baba Minami, Sato Masanao, Kitoh Katsuya, Takashima Yasuhiro. The distribution pattern of alpha 2,3-and alpha 2,6-linked sialic acids affects host cell preference in Toxoplasma gondii EXPERIMENTAL PARASITOLOGY. 2015.08; 155 74-81. ( DOI )

  17. Rahman Moizur, Azad Md. Thoufic Anam, Nahar Lovely, Rouf Shah Md. Abdur, Ohya Kenji, Chiou Shih-Pin, Baba Minami, Kitoh Katsuya, Takashima Yasuhiro. Age-Specificity of Toxoplasma gondii Seroprevalence in Sheep, Goats and Cattle on Subsistence Farms in Bangladesh JOURNAL OF VETERINARY MEDICAL SCIENCE. 2014.09; 76 (9): 1257-1259. ( DOI )

  18. Takeshi Hayashi, Akihiro Unno, Minami Baba, Tamio Ohno, Katsuya Kitoh, Yasuhiro Takashima. CD44 mediated Hyaluronan adhesion of Toxoplasma gondii-infected leukocytes PARASITOLOGY INTERNATIONAL. 2014.04; 63 (2): 479-484. ( DOI )

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Conference Activities & Talks 【 display / non-display

  1. RON4 is involved in attachment ability and motility of Plasmodium sporozoites necessary for invasion of hepatocyte and cell traversal. 2022.09.08

  2. RON4 is required for the efficient hepatocyte invasion and gliding motility by Plasmodium sporozoites. 2021.09.29

  3. RON4 is involved in sporozoite motility and liver invasion. 2020.02.24 Lorne Victoria Australia

  4. The role of RON4 in Plasmodium sporozoite infection of the liver. 2019.11.22 National Harbor MD USA

  5. RALP1 is localized to rhoptries in sporozoites and involved in infection of the mammalian liver. 2018.10.29 New Orleans LA USA

  6. RALP1 is involved in Plasmodium sporozoite transmission to mammalian hosts. 2018.09.12 愛媛県松山市

  7. 馬場 みなみ, 鬼頭 克也, 高島 康弘. Toxoplasma gondii感染白血球の血流内および標的臓器内での挙動. 第158回日本獣医学会学術集会 2015.09.07 青森県十和田市

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Awards & Honors 【 display / non-display

  • Best Presentation Award,The 86th Annual Meeting of the Japanese Society of Parasitology,2017.05

  • BPA,2016.08