基本情報

写真a

金山 敬子(カナヤマ ケイコ)

KANAYAMA Keiko


職名

助教

出身学校 【 表示 / 非表示

  • 北海道大学  水産学部  生物生産科学科  2007年03月  卒業

出身大学院 【 表示 / 非表示

  • 北海道大学  医科学研究科  遺伝子病制御研究所 分子免疫分野  修士課程  2009年03月  修了

  • 北海道大学  医学研究科  遺伝子病制御研究所 分子免疫分野  博士課程  2013年03月  修了

取得学位 【 表示 / 非表示

  • 博士(医学)  北海道大学

経歴(学内) 【 表示 / 非表示

  • 2021年12月
    -
    2022年03月
    東京医科歯科大学 難治疾患研究所 難治病態研究部門 発生再生生物学分野 特任助教
  • 2022年04月
     
     
    東京医科歯科大学 難治疾患研究所 難治病態研究部門 発生再生生物学分野 助教
  • 2022年05月
    -
    現在
    東京医科歯科大学 難治疾患研究所 未来生命科学研究部門 発生再生生物学分野 助教

経歴(学外) 【 表示 / 非表示

  • 2013年04月
    -
    2015年10月
    デューク大学 ポスドク
  • 2015年11月
    -
    2017年05月
    デューク大学 ポスドク
  • 2018年10月
    -
    2021年06月
    学校法人順天堂 順天堂大学 医学部耳鼻咽喉科学講座 内耳再生医療・遺伝子治療研究グループ 研究補助員
 

論文・総説 【 表示 / 非表示

  1. Yazan Alwarawrah, Keiko Danzaki, Amanda G Nichols, Brian E Fee, Cheryl Bock, Gary Kucera, Laura P Hale, Gregory A Taylor, Nancie J MacIver. Irgm1 regulates metabolism and function in T cell subsets. Scientific Reports. 2022.01; 12 (1): 850. ( PubMed, DOI )

  2. Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Kyoko Shirai, Atsushi Kawano, Katsuhisa Ikeda, Kazusaku Kamiya. Modeling gap junction beta 2 gene-related deafness with human iPSC. Human Molecular Genetics. 2021.07; 30 (15): 1429-1442. ( PubMed, DOI )

  3. Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Madoka Iizumi, Takahiro Shiga, Rina Matsuoka, Takashi Anzai, Remi Hibiya-Motegi, Shori Tajima, Katsuhisa Ikeda, Wado Akamatsu, Kazusaku Kamiya. Generation of two iPSC lines from siblings of a homozygous patient with hearing loss and a heterozygous carrier with normal hearing carrying p.G45E/Y136X mutation in GJB2. Stem Cell Research. 2021.05; 53 102290. ( PubMed, DOI )

  4. Ichiro Fukunaga, Yoko Oe, Cheng Chen, Keiko Danzaki, Sayaka Ohta, Akito Koike, Katsuhisa Ikeda, Kazusaku Kamiya. Differentiation of Embryonic Stem Cells. Frontiers in Cell and Developmental Biology. 2021.04; 9 602197. ( PubMed, DOI )

  5. M Elizabeth Deerhake, Keiko Danzaki, Makoto Inoue, Emre D Cardakli, Toshiaki Nonaka, Nupur Aggarwal, William E Barclay, Ru-Rong Ji, Mari L Shinohara. Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M. Immunity. 2021.03; 54 (3): 484-498.e8. ( PubMed, DOI )

  6. Ichiro Fukunaga, Kyoko Shirai, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Takahiro Shiga, Cheng Chen, Katsuhisa Ikeda, Wado Akamatsu, Atsushi Kawano, Kazusaku Kamiya. Generation of two induced pluripotent stem cell lines from PBMCs of siblings carrying c.235delC mutation in the GJB2 gene associated with sensorineural hearing loss. Stem Cell Research. 2020.07; 47 101910. ( PubMed, DOI )

  7. Shori Tajima, Keiko Danzaki, Katsuhisa Ikeda, Kazusaku Kamiya. Degradation and modification of cochlear gap junction proteins in the early development of age-related hearing loss. Experimental & Molecular Medicine. 2020.01; 52 (1): 166-175. ( PubMed, DOI )

  8. Ichiro Fukunaga, Takahiro Shiga, Cheng Chen, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Rina Matsuoka, Takashi Anzai, Remi Hibiya-Motegi, Shori Tajima, Katsuhisa Ikeda, Wado Akamatsu, Kazusaku Kamiya. Generation of the induced pluripotent stem cell (hiPSC) line (JUFMDOi004-A) from a patient with hearing loss carrying GJB2 (p.V37I) mutation. Stem Cell Research. 2019.12; 43 101674. ( PubMed, DOI )

  9. Jennifer Rebeles, William D Green, Yazan Alwarawrah, Amanda G Nichols, William Eisner, Keiko Danzaki, Nancie J MacIver, Melinda A Beck. Obesity-Induced Changes in T-Cell Metabolism Are Associated With Impaired Memory T-Cell Response to Influenza and Are Not Reversed With Weight Loss. The Journal of Infectious Diseases. 2019.04; 219 (10): 1652-1661. ( PubMed, DOI )

  10. Masashi Kanayama, Shengjie Xu, Keiko Danzaki, Jason R Gibson, Makoto Inoue, Simon G Gregory, Mari L Shinohara. Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin. Nature Immunology. 2017.09; 18 (9): 973-984. ( PubMed, DOI )

  11. Sivan Cohen, Keiko Danzaki, Nancie J MacIver. Nutritional effects on T-cell immunometabolism. European Journal of Immunology. 2017.02; 47 (2): 225-235. ( PubMed, DOI )

  12. Keiko Danzaki, Masashi Kanayama, Oscar Alcazar, Mari L Shinohara. Osteopontin has a protective role in prostate tumor development in mice. European Journal of Immunology. 2016.11; 46 (11): 2669-2678. ( PubMed, DOI )

  13. Masashi Kanayama, Keiko Danzaki, You-Wen He, Mari L Shinohara. Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis. International Immunology. 2016.09; 28 (9): 463-469. ( PubMed, DOI )

  14. Valerie A Gerriets, Keiko Danzaki, Rigel J Kishton, William Eisner, Amanda G Nichols, Donte C Saucillo, Mari L Shinohara, Nancie J MacIver. Leptin directly promotes T-cell glycolytic metabolism to drive effector T-cell differentiation in a mouse model of autoimmunity. European Journal of Immunology. 2016.05; 46 (8): 1970-1983. ( PubMed, DOI )

  15. Masashi Kanayama, Makoto Inoue, Keiko Danzaki, Gianna Hammer, You-Wen He, Mari L Shinohara. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nature Communications. 2015.01; 6 5779. ( PubMed, DOI )

  16. Keiko Danzaki, Yutaka Matsui, Masahiro Ikesue, Daichi Ohta, Koyu Ito, Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Yoichiro Iwakura, Hideo Yagita, Hiroyuki Tsutsui, Toshimitsu Uede. Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2012.02; 32 (2): 273-280. ( PubMed, DOI )

  17. Masashi Kanayama, Junko Morimoto, Yutaka Matsui, Masahiro Ikesue, Keiko Danzaki, Daisuke Kurotaki, Koyu Ito, Toshimichi Yoshida, Toshimitsu Uede. α9β1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation. The Journal of Immunology. 2011.12; 187 (11): 5851-5864. ( PubMed, DOI )

  18. Masahiro Ikesue, Yutaka Matsui, Daichi Ohta, Keiko Danzaki, Koyu Ito, Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Tetsuhito Kojima, Hiroyuki Tsutsui, Toshimitsu Uede. Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization. Arteriosclerosis, Thrombosis, and Vascular Biology. 2011.05; 31 (5): 1066-1074. ( PubMed, DOI )

  19. Yutaka Matsui, Masahiro Ikesue, Keiko Danzaki, Junko Morimoto, Mami Sato, Shinya Tanaka, Tetsuhito Kojima, Hiroyuki Tsutsui, Toshimitsu Uede. Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction. Circulation Research. 2011.05; 108 (11): 1328-1339. ( PubMed, DOI )

▼全件表示

受賞学術賞 【 表示 / 非表示

  • Award for Outstanding Abstract, Department of Pediatrics Research Retreat,2017年04月

  • 第38回分子生物学会年会 海外若手研究者招聘企画,日本分子生物学会,2015年12月

  • 第8回 音羽博次奨学基金,北海道大学大学院 医学研究科,2012年09月