Personnel Information

写真a

HANAZONO Yuya


Job title

Associate Professor
To the head of this page.▲

Graduating School 【 display / non-display 】

  • Kyoto University, Faculty of Science, 2009.03, Graduated

To the head of this page.▲

Graduate School 【 display / non-display 】

  • Kyoto University, Graduate School, Division of Natural Science, Master's Course, 2011.03, Completed

  • Kyoto University, Graduate School, Division of Natural Science, Doctor's Course, 2014.03, Completed

To the head of this page.▲

Campus Career 【 display / non-display 】

  • 2021.07
    -
    2022.04
    Tokyo Medical and Dental University， Medical Research Institute， Advanced Molecular Medicine， Structural Biology， Assistant Professor
  • 2021.07
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Life Science and Technology， Life Science and Technology， Structural Biology， Assistant Professor
  • 2022.05
    -
    2024.01
    Tokyo Medical and Dental University， Medical Research Institute， Division of Biological Data Science， Department of Structural Biology， Assistant Professor
  • 2024.02
    -
    Now
    Tokyo Medical and Dental University， Medical Research Institute， Division of Biological Data Science， Department of Structural Biology， Associate Professor
To the head of this page.▲

Research Areas 【 display / non-display 】

  • Structural biochemistry

To the head of this page.▲
 

Published Papers & Misc 【 display / non-display 】

  1. Yoshida M, Hanazono Y, Numoto N, Nagao S, Yabuno S, Kitagawa Y, Sekiguchi H, Ito N, Azuma T, Oda M. Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Archives of biochemistry and biophysics. 2024.06; 758 110068. ( PubMed, DOI )

  2. Omori S, Hanazono Y, Nishi H, Kinoshita K. The role of the STAS domain in SLC26A9 for chloride ion transporter function. Biophysical journal. 2024.05; 123 (12): 1751-1762. ( PubMed, DOI )

  3. Yuya Hanazono, Yu Hirano, Taro Tamada, Kunio Miki. Description of peptide bond planarity from high-resolution neutron crystallography Biophysics and Physicobiology. 2023.09; 20 (3): e200035.

  4. Hanazono Yuya, Hirano Yu, Takeda Kazuki, Kusaka Katsuhiro, Tamada Taro, Miki Kunio. Revisiting the concept of peptide bond planarity in an iron-sulfur protein by neutron structure analysis SCIENCE ADVANCES. 2022.05; 8 (20): eabn2276. ( PubMed, DOI )

  5. Lensink MF, Brysbaert G, Mauri T, Nadzirin N, Velankar S, Chaleil RAG, Clarence T, Bates PA, Kong R, Liu B, Yang G, Liu M, Shi H, Lu X, Chang S, Roy RS, Quadir F, Liu J, Cheng J, Antoniak A, Czaplewski C, GiełdoŃ A, Kogut M, Lipska AG, Liwo A, Lubecka EA, Maszota-Zieleniak M, Sieradzan AK, Ślusarz R, Wesołowski PA, ZiĘba K, Del Carpio Muñoz CA, Ichiishi E, Harmalkar A, Gray JJ, Bonvin AMJJ, Ambrosetti F, Honorato RV, Jandova Z, Jiménez-García B, Koukos PI, Van Keulen S, Van Noort CW, Réau M, Roel-Touris J, Kotelnikov S, Padhorny D, Porter KA, Alekseenko A, Ignatov M, Desta I, Ashizawa R, Sun Z, Ghani U, Hashemi N, Vajda S, Kozakov D, Rosell M, Rodríguez-Lumbreras LA, Fernandez-Recio J, Karczynska A, Grudinin S, Yan Y, Li H, Lin P, Huang SY, Christoffer C, Terashi G, Verburgt J, Sarkar D, Aderinwale T, Wang X, Kihara D, Nakamura T, Hanazono Y, Gowthaman R, Guest JD, Yin R, Taherzadeh G, Pierce BG, Barradas-Bautista D, Cao Z, Cavallo L, Oliva R, Sun Y, Zhu S, Shen Y, Park T, Woo H, Yang J, Kwon S, Won J, Seok C, Kiyota Y, Kobayashi S, Harada Y, Takeda-Shitaka M, Kundrotas PJ, Singh A, Vakser IA, DapkŪnas J, Olechnovič K, Venclovas Č, Duan R, Qiu L, Zhang S, Zou X, Wodak SJ. Prediction of protein assemblies, the next frontier: The CASP14-CAPRI experiment. Proteins. 2021.12; 89 (12): 1800-1823. ( PubMed, DOI )

  6. Yosuke Inoue, Yuya Hanazono, Kentaro Noi, Akihiro Kawamoto, Masato Kimatsuka, Ryuhei Harada, Kazuki Takeda, Ryoichi Kita, Natsuki Iwamasa, Kyoka Shibata, Keiichi Noguchi, Yasuteru Shigeta, Keiichi Namba, Teru Ogura, Kunio Miki, Kyosuke Shinohara, Masafumi Yohda. Split conformation of Chaetomium thermophilum Hsp104 disaggregase. Structure. 2021.07; 29 (7): 721-730. ( PubMed, DOI )

  7. Yuya Hanazono, Kazuki Takeda, Kunio Miki. Characterization of perdeuterated high-potential iron-sulfur protein with high-resolution X-ray crystallography. Proteins. 2020.02; 88 (2): 251-259. ( PubMed, DOI )

  8. Yang Tai, Kiyofumi Takaba, Yuya Hanazono, Hoang Anh Dao, Kunio Miki, Kazuki Takeda. X-ray crystallographic studies on the hydrogen isotope effects of green fluorescent protein at sub-ångström resolutions. Acta Crystallogr D Struct Biol. 2019.12; 75 (12): 1096-1106. ( PubMed, DOI )

  9. Kiyofumi Takaba, Yang Tai, Haruhiko Eki, Hoang-Anh Dao, Yuya Hanazono, Kazuya Hasegawa, Kunio Miki, Kazuki Takeda. Subatomic resolution X-ray structures of green fluorescent protein. IUCrJ. 2019.05; 6 (3): 387-400. ( PubMed, DOI )

  10. Yuya Hanazono, Kazuki Takeda, Kunio Miki. Co-translational folding of α-helical proteins: structural studies of intermediate-length variants of the λ repressor. FEBS Open Bio. 2018.08; 8 (8): 1312-1321. ( PubMed, DOI )

  11. Hiraku Ohno, Kazuki Takeda, Satomi Niwa, Tomotaka Tsujinaka, Yuya Hanazono, Yu Hirano, Kunio Miki. Crystallographic characterization of the high-potential iron-sulfur protein in the oxidized state at 0.8 Å resolution. PLoS One. 2017.05; 12 (5): e0178183. ( PubMed, DOI )

  12. Yuya Hanazono, Kazuki Takeda, Kunio Miki. Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein. Sci Rep. 2016.10; 6 34654. ( PubMed, DOI )

  13. Yuya Hanazono, Kazuki Takeda, Kunio Miki. Characterization of the Nqo5 subunit of bacterial complex I in the isolated state. FEBS Open Bio. 2016.06; 6 (7): 687-695. ( PubMed, DOI )

  14. Yuya Hanazono, Kazuki Takeda, Satomi Niwa, Masahito Hibi, Naoya Takahashi, Tamotsu Kanai, Haruyuki Atomi, Kunio Miki. Crystal structures of chitin binding domains of chitinase from Thermococcus kodakarensis KOD1. FEBS Lett. 2016.01; 590 (2): 298-304. ( PubMed, DOI )

  15. Yuya Hanazono, Kazuki Takeda, Toshihiko Oka, Tetsuya Abe, Taichi Tomonari, Nobuhiko Akiyama, Yoshiki Aikawa, Masafumi Yohda, Kunio Miki. Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe. Structure. 2013.02; 21 (2): 220-228. ( PubMed, DOI )

  16. Yuya Hanazono, Kazuki Takeda, Masafumi Yohda, Kunio Miki. Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0. J Mol Biol. 2012.09; 422 (1): 100-108. ( PubMed, DOI )

  17. Kazuki Takeda, Takuro Hayashi, Tetsuya Abe, Yu Hirano, Yuya Hanazono, Masafumi Yohda, Kunio Miki. Dimer structure and conformational variability in the N-terminal region of an archaeal small heat shock protein, StHsp14.0. J Struct Biol. 2011.04; 174 (1): 92-99. ( PubMed, DOI )

▼display all

To the head of this page.▲

Conference Activities & Talks 【 display / non-display 】

  1. Hansaka N. Thilakarathne N. M., Takashi Misawa, Yosuke Demizu, Yuya Hanazono, Nobutoshi Ito, Hiroyuki Kagechika, Shinya Fujii. Structure-activity relationship (SAR) study of non-secosteroidal diphenyl-carborane based VDR ligands. 4th Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS2024) 2024.11.07

  2. Yuya Hanazono. Structural analysis of amide protons using high-resolution neutron crystallography. Japan-Taiwan Bilateral Seminar on Crystallography: “Frontier of Crystallography” 2024.11.07

  3. Hansaka N. Thilakarathne N. M., Takashi Misawa, Yosuke Demizu, Yuya Hanazono, Nobutoshi Ito, Hiroyuki Kagechika, Shinya Fujii. Structure-activity relationship (SAR) study of hydrophobic moiety of nonsecosteroidal VDR ligands using diphenylsilane scaffold. 21st IUPAB Congress 2024 2024.06.25

  4. Yuya Hanazono, Yu Hirano, Nobutoshi Ito, Taro Tamada, Kunio Miki. Fine structure analysis of protein: Unraveling molecular details through ultra-high-resolution X-ray and neutron crystallography. The 18th International Symposium of the Institute Network for Biomedical Sciences 2023.10.06

  5. Yuya Hanazono, Yu Hirano, Kazuki Takeda, Katsuhiro Kusaka, Taro Tamada, Kunio Miki. High-resolution structure of an electron-transfer protein by neutron crystallography. The 4th International Forum on Quantum Metrology and Sensing 2021.12.08 on-line

  6. Hafumi Nishi, Yuya Hanazono, Kengo Kinoshita. Comprehensive analysis of genetic variations on human SLC transporters. The 29th Conference on Intelligent Systems for Molecular Biology and the 20th European Conference on Computational Biology (ISMB/ECCB2021) 2021.07.25 on-line

▼display all

To the head of this page.▲

Awards & Honors 【 display / non-display 】

  • Travel Fellowship Awards (Yuya Hanazono)，IUPAB/NanoLSI Workshop on Computational Biophysics of Atomic Force Microscopy，2022.09

  • Early Career Presentation Award (Yuya Hanazono)，Biophysical Society of Japan，2022.09

To the head of this page.▲
 

Campus class subject 【 display / non-display 】

  • Advanced Chemical Biology，2024 - Now

  • Special Lecture on Molecular Structures，2022 - Now

To the head of this page.▲

External class subject 【 display / non-display 】

  • Biophysical Chemistry，Ochanomizu University

To the head of this page.▲