Personnel Information

写真a

IRABU Hitoshi


Job title

Assistant Professor
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Graduating School 【 display / non-display 】

  • Kanazawa University, Faculty of Medicine, 2013.03, Graduated

  • Kanazawa University, Graduate School of Medical Science, 2020.09, Graduated

  • Kanazawa University, 2020.09, Graduated

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Graduate School 【 display / non-display 】

  • Kanazawa University, Doctor's Course, 2020.09, Completed

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Campus Career 【 display / non-display 】

  • 2021.04
    -
    2022.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Endowed Departments， Department of Lifetime Clinical Immunology， Assistant Professor
  • 2022.04
    -
    2022.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Endowed Departments， Department of Pediatrics, Perinatal and Maternal Medicine， Assistant Professor
  • 2022.10
    -
    Now
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Medicine， Department of Pediatrics, Perinatal, and Women's Medicine， Pediatrics， Assistant Professor
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Research Areas 【 display / non-display 】

  • Connective tissue disease and allergy

  • Connective tissue disease and allergy

  • Nephrology

  • Embryonic medicine and pediatrics

  • Immunology

  • Connective tissue disease and allergy

  • Nephrology

  • Embryonic medicine and pediatrics

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Published Papers & Misc 【 display / non-display 】

  1. Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Maho Hatano, Kei Takasawa, Takahiro Kamiya, Keiji Akamine, Takayuki Tanaka, Toshinori Minato, Makoto Ono, Koji Yokoyama, Atsuko Arisaka, Takahiro Yasumi, Kazuyuki Ueno, Shuhei Fujita, Yumi Tanaka, Daisuke Hayashi, Hiroki Nishikawa, Yuji Fujita, Yuki Yuza, Masaaki Mori, Tomohiro Morio, Masaki Shimizu. Pathogenic role and diagnostic utility of interferon-α in histiocytic necrotizing lymphadenitis. Clin Immunol. 2024.07; 266 110324. ( PubMed, DOI )

  2. Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Mao Mizuta, Yasuo Nakagishi, Naomi Iwata, Koji Yokoyama, Junko Yasumura, Keiji Akamine, Kazuyuki Ueno, Shuhei Fujita, Kenichi Watanabe, Shojiro Watanabe, Hiroki Nishikawa, Junya Fujimura, Masaaki Mori, Masaki Shimizu. Serum interleukin-18 levels can improve the diagnostic performance of the PRINTO and ILAR criteria for systemic juvenile idiopathic arthritis. Cytokine. 2024.07; 182 156719. ( PubMed, DOI )

  3. Susumu Yamazaki, Masaki Shimizu, Ayane Yakabe, Eisuke Inage, Keisuke Jimbo, Mitsuyoshi Suzuki, Futaba Miyaoka, Shuya Kaneko, Hitoshi Irabu, Asami Shimbo, Yoshiyuki Ohtomo, Masaaki Mori, Tomohiro Morio, Toshiaki Shimizu. Successful treatment with tofacitinib for anti-melanoma differentiation-associated gene 5 antibody-positive juvenile dermatomyositis: case reports and review of the literature. Immunol Med. 2024.06; 47 (2): 110-117. ( PubMed, DOI )

  4. Saki Kanda, Asami Shimbo, Yoshitaka Nakamura, Ryosuke Matsuno, Shuya Kaneko, Hitoshi Irabu, Kazunari Kaneko, Masaki Shimizu. Anti-Ku antibody-positive systemic sclerosis and idiopathic inflammatory myopathies overlap syndrome in children: a report of two cases and a review of the literature. Clin Rheumatol. 2023.12; 42 (12): 3411-3417. ( PubMed, DOI )

  5. Ryosuke Wakatsuki, Yoshiho Hatai, Kentaro Okamoto, Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Masaki Shimizu, Hirokazu Kanegane, Makoto Ono. An infant with A20 haploinsufficiency presenting with periodic fever syndrome: A case report. Int J Rheum Dis. 2023.01; ( PubMed, DOI )

  6. Kaneko Shuya, Shimizu Masaki, Shimbo Asami, Irabu Hitoshi, Yamazaki Susumu, Kanamori Toru, Udagawa Tomohiro, Morio Tomohiro, Mori Masaaki. A girl with hearing loss, dizziness, hypertension, and pyelonephritis with ureteral edema: Questions PEDIATRIC NEPHROLOGY. 2022.12; 37 (12): 3057-3058. ( PubMed, DOI )

  7. Kaneko Shuya, Shimizu Masaki, Shimbo Asami, Irabu Hitoshi, Yamazaki Susumu, Kanamori Toru, Udagawa Tomohiro, Morio Tomohiro, Mori Masaaki. A girl with hearing loss, dizziness, hypertension, and pyelonephritis with ureteral edema: Answers PEDIATRIC NEPHROLOGY. 2022.05; ( PubMed, DOI )

  8. Shimizu M, Shimbo A, Irabu H, Inoue N, Kuroda M. Hirayama disease. Joint bone spine. 2022.02; 89 (4): 105354. ( PubMed, DOI )

  9. Yamaguchi Y, Takasawa K, Irabu H, Hiratoko K, Ichigi Y, Hirata K, Tamura Y, Murakoshi M, Yamashita M, Nakatani H, Shimoda M, Ishii T, Udagawa T, Shimizu M, Kanegane H, Morio T. Infliximab treatment for refractory COVID-19-associated multisystem inflammatory syndrome in a Japanese child. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022.01; 28 (6): 814-818. ( PubMed, DOI )

  10. Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Tasaki Y, Ohta K, Yachie A, Wada T. Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis. Pediatric research. 2021.02; 89 (3): 667-672. ( PubMed, DOI )

  11. Shimizu M, Inoue N, Mizuta M, Irabu H, Okajima M, Honda Y, Nihira H, Izawa K, Yachie A, Wada T. Successful treatment of spondyloenchondrodysplasia with baricitinib. Rheumatology (Oxford, England). 2021.02; 60 (2): e44-e46. ( PubMed, DOI )

  12. Mizuta M, Shimizu M, Irabu H, Usami M, Inoue N, Nakagishi Y, Wada T, Yachie A. Comparison of serum cytokine profiles in macrophage activation syndrome complicating different background rheumatic diseases in children. Rheumatology (Oxford, England). 2021.01; 60 (1): 231-238. ( PubMed, DOI )

  13. Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis during tocilizumab therapy. Pediatric research. 2020.12; 88 (6): 934-939. ( PubMed, DOI )

  14. Yokoyama T, Takemura Y, Irabu H, Taniguchi C, Jinkawa A, Yamamiya M, Obata M, Miyashita K, Inoue M, Sakazume S, Ohta K. Clinical Characteristics of Pediatric Pyelonephritis Without Pyuria or Bacteriuria. The Pediatric infectious disease journal. 2020.05; 39 (5): 385-388. ( PubMed, DOI )

  15. Sakumura N, Irabu H, Inoue N, Mizuta M, Shimizu M. Clinical usefulness of longitudinal IL-6 monitoring in a patient with Takayasu aortitis receiving tocilizumab. Rheumatology (Oxford, England). 2020.01; 59 (1): 252-254. ( PubMed, DOI )

  16. Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Ohta K, Yachie A. Clinical Significance of Serum Galactose-Deficient IgA1 Level in Children with IgA Nephropathy. Journal of immunology research. 2020; 2020 4284379. ( PubMed, DOI )

  17. Takakura M, Shimizu M, Irabu H, Sakumura N, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Clinical immunology (Orlando, Fla.). 2019.11; 208 108252. ( PubMed, DOI )

  18. Usami M, Shimizu M, Mizuta M, Inoue N, Irabu H, Sakumura N, Nakagishi Y, Yachie A. Extensive serum biomarker analysis in patients with macrophage activation syndrome associated with systemic lupus erythematosus. Clinical immunology (Orlando, Fla.). 2019.11; 208 108255. ( PubMed, DOI )

  19. Kaneko S, Shimizu M, Irabu H, Yachie A. Acute generalized exanthematous pustulosis in a child with fasciitis. Pediatrics international : official journal of the Japan Pediatric Society. 2019.09; 61 (9): 938. ( PubMed, DOI )

  20. Kaneko Shuya, Shimizu Masaki, Irabu Hitoshi, Yachie Akihiro. 筋膜炎小児における急性汎発性発疹性膿疱症(Acute generalized exanthematous pustulosis in a child with fasciitis) Pediatrics International. 2019.09; 61 (9): 938. ( ichushi )

  21. Jinkawa A, Shimizu M, Nishida K, Kaneko S, Usami M, Sakumura N, Irabu H, Takakuwa M, Inoue N, Mizuta M, Ikawa Y, Fujita S, Yachie A. Cytokine profile of macrophage activation syndrome associated with Kawasaki disease. Cytokine. 2019.07; 119 52-56. ( PubMed, DOI )

  22. Shimizu Masaki, Irabu Hitoshi, Kaneda Hisashi, Ohta Kazuhide, Nozu Kandai. 同胞で認められたPLCE1変異を伴う家族性巣状分節性糸球体硬化症(Familial focal segmental glomerulosclerosis with PLCE1 mutation in siblings) Pediatrics International. 2019.07; 61 (7): 726-727. ( ichushi )

  23. Shimizu M, Irabu H, Kaneda H, Ohta K, Nozu K. Familial focal segmental glomerulosclerosis with PLCE1 mutation in siblings. Pediatrics international : official journal of the Japan Pediatric Society. 2019.07; 61 (7): 726-727. ( PubMed, DOI )

  24. Yokoyama Tadafumi, Takemura Yuta, Taniguchi Chihiro, Jinkawa Asumi, Yamamiya Mari, Obata Misato, Miyashita Kengo, Inoue Mika, Sakazume Shinobu, Ohta Kazuhide, Irabu Hitoshi, Inoue Natsumi, Shimizu Masaki. 膿尿や細菌尿を伴わない急性腎盂腎炎の臨床的特徴(Clinical characteristics of the acute pyelonephritis without pyuria or bacteriuria) 日本小児腎臓病学会雑誌. 2019.05; 32 (1Suppl.): 187. ( ichushi )

  25. Fujita Shuhei, Nishida Keigo, Irabu Hitoshi, Nakagawa Ryo, Futatani Takeshi, Igarashi Noboru, Usuda Kazuo, Nagata Yoshiki, Ohno Seiko, Horie Minoru, Hatasaki Kiyoshi. 11歳と15歳の姉妹において起立性調節障害およびてんかんとして管理されたカテコラミン誘発多形性心室頻拍(Catecholaminergic polymorphic ventricular tachycardia managed as orthostatic dysregulation and epilepsy in 11- and 15-year-old sisters) Pediatrics International. 2018.11; 60 (11): 998-1001. ( ichushi )

  26. Fujita S, Nishida K, Irabu H, Nakagawa R, Futatani T, Igarashi N, Usuda K, Nagata Y, Ohno S, Horie M, Hatasaki K. Catecholaminergic polymorphic ventricular tachycardia managed as orthostatic dysregulation and epilepsy in 11- and 15-year-old sisters. Pediatrics international : official journal of the Japan Pediatric Society. 2018.11; 60 (11): 998-1001. ( PubMed, DOI )

  27. Shimizu M, Inoue N, Kuroda M, Irabu H, Takakura M, Kaneda H, Sugimoto N, Ohta K, Yachie A. Serum ferritin as an indicator of the development of encephalopathy in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome. Clinical and experimental nephrology. 2017.12; 21 (6): 1083-1087. ( PubMed, DOI )

  28. Shimizu Masaki, Inoue Natsumi, Kuroda Mondo, Irabu Hitoshi, Takakura Maiko, Kaneda Hisashi, Sugimoto Naotoshi, Ohta Kazuhide, Yachie Akihiro. 腸管出血性大腸菌誘発性の溶血性尿毒症症候群における脳障害発症の指標としての血清フェリチン(Serum ferritin as an indicator of the development of encephalopathy in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome) Clinical and Experimental Nephrology. 2017.12; 21 (6): 1083-1087. ( ichushi )

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Conference Activities & Talks 【 display / non-display 】

  1. Irabu H, Shimizu M, Takakuwa M, Sakumura N, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.. Annual European Congress of Rheumatology: EULAR 2019, 2019.06.14

  2. Irabu H, Shimizu M, Takakuwa M, Sakumura N, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.. Annual European Congress of Rheumatology: EULAR 2019, 2019.06.14

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