Personnel Information

写真a

SASAGAWA Youhei


Job title

Associate Professor

Homepage URL

https://www.nikaidolab.org/

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Campus Career 【 display / non-display 】

  • 2021.04
    -
    2022.04
    Tokyo Medical and Dental University， Medical Research Institute， Medical Genomics， Department of Functional Genome Informatics， Associate Professor
  • 2022.05
    -
    Now
    Tokyo Medical and Dental University， Medical Research Institute， Division of Biological Data Science， Department of Functional Genome Informatics， Associate Professor
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External Career 【 display / non-display 】

  • 2010.04
    -
    2013.03
    RIKEN Center for Developmental Biology, Functional Genomics Unit, Special Postdoctoral Researcher
  • 2013.04
    -
    2018.03
    Advanced Center for Computing and Communication, RIKEN, Bioinformatic research unit, Senior Scientist
  • 2018.04
    -
    2019.03
    RIKEN Center for Biosystems Dynamics Research: Wako, Saitama, Japan, Laboratory for Bioinformatics Research, Senior Scientist
  • 2019.04
    -
    2021.03
    RIKEN Center for Biosystems Dynamics Research: Wako, Saitama, Japan, Laboratory for Bioinformatics Research, Senior Scientist
  • 2019.06
    -
    Now
    Knowledge Palette, Inc., Adviser
  • 2021.04
    -
    Now
    Division of Medical Genomics, Medical Research Institute Tokyo Medical and Dental University, Department of Functional Genome Informatics,, Associate Professor
  • 2021.05
    -
    Now
    RIKEN, Laboratory for Bioinformatics ResearchRIKEN Center for Biosystems Dynamics Research, Visiting Scientist

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Research Areas 【 display / non-display 】

  • Molecular biology

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Published Papers & Misc 【 display / non-display 】

  1. Yasuyuki Shima, Henrik Skibbe, Yohei Sasagawa, Noriko Fujimori, Yoshimi Iwayama, Ayako Isomura-Matoba, Minoru Yano, Takumi Ichikawa, Itoshi Nikaido, Nobutaka Hattori, Tadafumi Kato. Distinctiveness and continuity in transcriptome and connectivity in the anterior-posterior axis of the paraventricular nucleus of the thalamus Cell Reports. 2023.10; 42 (10): ( DOI )

  2. Ogura Nao, Sasagawa Yohei, Ito Tasuku, Tameshige Toshiaki, Kawai Satomi, Sano Masaki, Doll Yuki, Iwase Akira, Kawamura Ayako, Suzuki Takamasa, Nikaido Itoshi, Sugimoto Keiko, Ikeuchi Momoko. WUSCHEL-RELATED HOMEOBOX 13 suppresses de novo shoot regeneration via cell fate control of pluripotent callus SCIENCE ADVANCES. 2023.07; 9 (27): eadg6983. ( PubMed, DOI )

  3. Takada Hitomi, Sasagawa Yohei, Yoshimura Mika, Tanaka Kaori, Iwayama Yoshimi, Hayashi Tetsutaro, Isomura-Matoba Ayako, Nikaido Itoshi, Kurisaki Akira. Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis NATURE COMMUNICATIONS. 2023.06; 14 (1): 3750. ( PubMed, DOI )

  4. Lin Chia-Wen, Septyaningtrias Dian E., Chao Hsu-Wen, Konda Mikiko, Atarashi Koji, Takeshita Kozue, Tamada Kota, Nomura Jun, Sasagawa Yohei, Tanaka Kaori, Nikaido Itoshi, Honda Kenya, McHugh Thomas J., Takumi Toru. A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model MOLECULAR PSYCHIATRY. 2022.05; 27 (8): 3343-3354. ( PubMed, DOI )

  5. Satoru Ishihara, Yohei Sasagawa, Takeru Kameda, Hayato Yamashita, Mana Umeda, Naoe Kotomura, Masayuki Abe, Yohei Shimono, Itoshi Nikaido. Local states of chromatin compaction at transcription start sites control transcription levels Nuclei Acids Research. 2021.07; gkab587 (14): 8007-8023. ( PubMed, DOI )

  6. Tomoyo Sawada, Thomas E. Chater, Yohei Sasagawa, Mika Yoshimura, Noriko Fujimori-Tonou, Kaori Tanaka, Kynon J. M. Benjamin, Apuã C. M. Paquola, Jennifer A. Erwin, Yukiko Goda, Itoshi Nikaido, Tadafumi Kato. Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids Molecular Psychiatry. 2020.08; 25 (11): 2695-2711. ( PubMed, DOI )

  7. Seiji Shiozawa, Mayutaka Nakajima, Junko Okahara, Yoko Kuortaki, Fumihiko Kisa, Sho Yoshimatsu, Mari Nakamura, Ikuko Koya, Mika Yoshimura, Yohei Sasagawa, Itoshi Nikaido, Erika Sasaki, Hideyuki Okano. Primed to naïve-like conversion of the common marmoset embryonic stem cells. Stem cells and development. 2020.03; 29 (12): 761-773. ( PubMed, DOI )

  8. Yohei SASAGAWA, Tetsutaro HAYASHI, Itoshi NIKAIDO. Strategies for Converting RNA to Amplifiable cDNA for Single-Cell RNA Sequencing Methods In: Suzuki Y. (eds) Single Molecule and Single Cell Sequencing. Advances in Experimental Medicine and Biology. 2019.04; 1129 1-17. ( PubMed, DOI )

  9. Tetsutaro Hayashi, Haruka Ozaki, Yohei Sasagawa, Mana Umeda, Hiroki Danno, Itoshi Nikaido. Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs Nature Communications. 2018.12; 9 (1): 619. ( PubMed, DOI )

  10. Hideki Kobayashi, Takahiko Nagahama, Wataru Arai, Yohei Sasagawa, Mana Umeda, Tetsutaro Hayashi, Itoshi Nikaido, Hiromi Watanabe, Kazumasa Oguri, Hiroshi Kitazato, Kantaro Fujioka, Yukari Kido, Hideto Takami. Polysaccharide hydrolase of the hadal zone amphipods Hirondellea gigas Bioscience, Biotechnology, and Biochemistry. 2018.04; 82 (7): 1123-1133. ( PubMed, DOI )

  11. Yohei Sasagawa, Hiroki Danno, Hitomi Takada, Masashi Ebisawa, Kaori Tanaka, Tetsutaro Hayashi, Akira Kurisaki, Itoshi Nikaido. Quartz-Seq2: A high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads Genome Biology. 2018.03; 19 (1): 29. ( PubMed, DOI )

  12. Muhchyi Chai, Tsukasa Sanosaka, Hironobu Okuno, Zhi Zhou, Ikuko Koya, Satoe Banno, Tomoko Andoh-Noda, Yoshikuni Tabata, Rieko Shimamura, Tetsutaro Hayashi, Masashi Ebisawa, Yohei Sasagawa, Itoshi Nikaido, Hideyuki Okano, Jun Kohyama. Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors Genes and Development. 2018.01; 32 (2): 165-180. ( PubMed, DOI )

  13. Haiyang Hu, Masahiro Uesaka, Song Guo, Kotaro Shimai, Tsai-Ming Lu, Fang Li, Satoko Fujimoto, Masato Ishikawa, Shiping Liu, Yohei Sasagawa, Guojie Zhang, Shigeru Kuratani, Jr-Kai Yu, Takehiro G. Kusakabe, Philipp Khaitovich, Naoki Irie. Constrained vertebrate evolution by pleiotropic genes NATURE ECOLOGY & EVOLUTION. 2017.11; 1 (11): 1722-1730. ( DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Yohei SASAGAWA. Single-cell RNA sequencing methods ~Quartz-Seq and next technology~. Expanding Frontiers of Genome Science II 2015.01.21

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