Personnel Information

写真a

OTA Yusuke


Job title

Assistant Professor

Mail Address

y-ota.micr@tmd.ac.jp

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Graduating School 【 display / non-display 】

  • Shinshu University, Faculty of Medicine, 2013.03, Graduated

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Graduate School 【 display / non-display 】

  • Shinshu University, Graduate School, Division of Medical Sciences, Master's Course, 2015.03, Completed

  • Hamamatsu University School of Medicine, Graduate School, Division of Medical Sciences, Doctor's Course, 2021.03, Completed

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Campus Career 【 display / non-display 】

  • 2021.03
    -
    2023.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Biomedical Sciences and Engineering， Division of Biomedical Laboratory Sciences， Department of Molecular Microbiology， Assistant Professor
  • 2023.05
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Biomedical Sciences and Engineering， Division of Biomedical Laboratory Sciences， Department of Molecular Microbiology and Immunology， Assistant Professor
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External Career 【 display / non-display 】

  • 2015.04
    -
    2021.02
    , Medical Technologist
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Research Areas 【 display / non-display 】

  • Environmental impact assessment

  • General internal medicine

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Qualification Acquired 【 display / non-display 】

  • Medical Technologist

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Published Papers & Misc 【 display / non-display 】

  1. Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Masato Suzuki, Mitsunori Yoshida, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Samuel Ablordey, Ryoichi Saito. Colistin Resistance Mediated by Mcr-3-Related Phosphoethanolamine Transferase Genes in Aeromonas Species Isolated from Aquatic Environments in Avaga and Pakro Communities in the Eastern Region of Ghana Infection and Drug Resistance. 2024.07; 17 3011-3023. ( PubMed, DOI )

  2. 1. Yusuke Ota, Kei Yasunaga, Samiratu Mahazu, Isaac Prah, Satoshi Nagai, Takaya Hayashi, Masato Suzuki, Mitsunori Yoshida, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Yoshiaki Gu, Ryoichi Saito. Comparative evaluation of analytical pipelines for Illumina short- and Nanopore long-read 16S rRNA gene amplicon sequencing with mock microbial communities Journal of Microbiological Methods. 2024.04; 221 106929. ( PubMed, DOI )

  3. Yusuke Kanno, Shuzo Masui, Yusuke Ota, Ryoichi Saito, Takasi Nisisako. Electrochemical sensing strategies for on-site testing ofpathogenic nucleic acids Electrochemical Science Advances. 2024.04; 1-10. ( DOI )

  4. Yusuke Ota, Isaac Prah, Samiratu Mahazu, Yoshiaki Gu, Yoko Nukui, Ryuji Koike, Ryoichi Saito. Novel insights into genetic characteristics of blaGES-encoding plasmids from hospital sewage Frontiers in Microbiology. 2023.08; 14 1209195. ( PubMed, DOI )

  5. Yusuke Ota, Kazuki Furuhashi, Nachi Hirai, Yuki Nagao, Jinko Ishikawa, Osanori Nagura, Keita Yamashita, Masato Maekawa. Utility of the MBT STAR-Cepha kit in detecting extended-spectrum β-lactamase producers in clinical urine samples and positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Journal of Microbiological Methods. 2023.06; 211 106756. ( PubMed, DOI )

  6. Yusuke Ota, Reina Okada, Hideyuki Takahashi, Ryoichi Saito. A mismatch amplification mutation assay for specific detection of ciprofloxacin-resistant Neisseria meningitidis Journal of Infection and Chemotherapy. 2023.05; 29 (5): 562-564. ( PubMed, DOI )

  7. Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito. Klebsiella Species and Enterobacter cloacae Isolates Harboring blaOXA-181 and blaOXA-48: Resistome, Fitness Cost, and Plasmid Stability Microbiology Spectrum . 2022.12; 10 (6): e0332022. ( PubMed, DOI )

  8. Yusuke Ota, Chihiro Tani Sassa, Masayo Kashiwagi, Chikako Okawara, Shuji Tohda, Ryoichi Saito. Complete genome sequence of an Enterobacter roggenkampii strain with reduced carbapenem susceptibility isolated from a home-visit nursing agency Microbiology Resource Announcements. 2022.08; e0035322. ( PubMed, DOI )

  9. Yusuke Ota, Reina Okada, Hideyuki Takahashi, Ryoichi Saito. Molecular detection of fluoroquinolone-resistant Neisseria meningitidis by using Mismatched PCR-restriction fragment length polymorphism technique Frontiers in Cellular and Infection Microbiology . 2022.07; 12 911911. ( PubMed, DOI )

  10. Ryoichi Saito, Jun Nakajima, Isaac Prah, Masatomo Morita, Samiratu Mahazu, Yusuke Ota, Ayuka Kobayashi, Shuji Tohda, Hajime Kamiya, Hideyuki Takahashi, Makoto Ohnishi. Penicillin- and ciprofloxacin-resistant invasive Neisseria meningitidis isolates from Japan. Microbiol Spectr. 2022.06; 10 (3): e0062722. ( PubMed, DOI )

  11. Yusuke Ota, Isaac Prah, Yoko Nukui, Ryuji Koike, Ryoichi Saito. blaKPC-2-encoding IncP-6 plasmids in Citrobacter freundii and Klebsiella variicola strains from hospital sewage in Japan Appl Environ Microbiol. 2022.04; 88 (8): e0001922. ( PubMed, DOI )

  12. Yusuke Ota, Natsune Hongou, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito. Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates. Anaerobe. 2021.12; 72 102462. ( PubMed, DOI )

  13. Yusuke Ota, Kazuki Furuhashi, Nachi Hirai, Jinko Ishikawa, Osanori Nagura, Katsumasa Yamanaka, Masato Maekawa. Evaluation of MBT STAR-Cepha and MBT STAR-Carba kits for the detection of extended-spectrum β-lactamases and carbapenemase producing microorganisms using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Journal of Microbiological Methods. 2021.04; 183 (106166 ): ( PubMed, DOI )

  14. Yusuke Ota, Kazuki Furuhashi, Wataru Hayashi, Nachi Hirai, Jinko Ishikawa, Osanori Nagura, Katsumasa Yamanaka, Kazuto Katahashi, Kotaro Aoki, Noriyuki Nagano, Masato Maekawa. Daptomycin resistant Enterococcus faecalis has a mutation in liaX, which encodes a surface protein that inhibits the LiaFSR systems and cell membrane remodeling Journal of infection and chemotherapy. 2021.01; 27 90-93. ( PubMed, DOI )

  15. Takehisa Matsumoto, Masayuki Hashimoto, Ching-Hao Teng, Po-Chuen Hsu, Yusuke Ota, Masaru Takamizawa, Ryosuke Kato, Tatsuya Negishi. Molecular characterization of a carbon dioxide-dependent Escherichia coli small-colony variant isolated from blood cultures International journal of medical microbiology. 2020.07; 310 (5): 151431. ( PubMed, DOI )

  16. Yusuke Ota, Kazuki Furuhashi, Yuki Nagao, Takamasa Nanba, Katsumasa Yamanaka, Jinko Ishikawa, Osanori Natura, Moriya Iwaizumi, Etsuko Hamada, Masato Maekawa. Detection of extended-spectrum β-lactamases producing Enterobacteriaceae using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry based MBT STAR-BL software module with β-lactamase inhibition assay depends on the bacterial strain J Microbiological Methods. 2019.12; 167 105734. ( PubMed, DOI )

  17. 太田悠介, 古橋一樹, 長尾侑紀, 山中勝正, 濵田悦子, 前川真人. 全自動尿中有形成分分析装置UF-5000による Escherichia coli を対象とした迅速な薬剤感受性検査法の構築. 臨床病理. 2019.06; 67 (6): 569-576.

  18. Yusuke Ota, Kazuki Furuhashi, Takamasa Nanba, Katsumasa Yamanaka, Jinko Ishikawa, Osanori Nagura, Etsuko Hamada, Masato Maekawa. A rapid and simple detection method for phenotypic antimicrobial resistance in Escherichia coli by loop-mediated isothermal amplification. Journal of Medical Microbiology. 2019.02; 68 (2): 169-177. ( PubMed, DOI )

  19. Kazuki Horiuchi, Takehisa Matsumoto, Yusuke Ota, Eriko Kasuga, Tatsuya Negishi, Tomomi Yaguchi, Mitsutoshi Sugano, Takayuki Honda. Addition of thymidine to culture media for accurate examination of thymidine-dependent small-colony variants of methicillin-resistant Staphylococcus aureus: A pilot study Journal of Microbiological Methods. 2015.03; 110 40-44. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Y Nukui, C Yamamoto, T Inaba, Y Aiso, J Nakajima, S Kanehira, K Sonobe, S Tohda, Y Ota, R Saito. . Genetic Analysis of Antimicrobial Resistant Enterobacteriaceae in Travelers and Patients Who Were Treated Overseas. ASM microbe 2023.06.05 Houston

  2. Yusuke Ota, Isaac Prah, Samiratu Mahazu, Yoshiaki Gu, Ryuji Koike, Ryoichi Saito. Molecular characterization of blaGES-encoding plasmids from hospital sewage in Japan. 33rd European Congress of Clinical. Microbiology and Infectious Diseases 2023.04 Copenhagen, Denmark

  3. Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito. Chromosomal mcr-3-related lipid A phosphoethanolamine transferases conferring colistin resistance in Aeromonas species from river water samples. The 33rd European Congress of Clinical Microbiology & Infectious Diseases 2023.04

  4. Taira Kawamura, Akari Samejima, Yukino Usui, Isaac Prah, Samiratu Mahazu, Yusuke Ota, Ryoichi Saito. Loss of GdpP function leads to reduced vancomycin susceptibility in Clostridioides difficile. The 33rd European Congress of Clinical Microbiology & Infectious Diseases 2023.04 Copenhagen, Denmark

  5. Miho Matsuba, Yusuke Ota, Samiratu Mahazu, Isaac Prah, Hideyuki Takahashi, Ryoichi Saito. Development of a rapid and simple assay for identification and serotyping of Neisseria meningitidis. The 33rd European Congress of Clinical Microbiology & Infectious Diseases 2023.04 Copenhagen, Denmark

  6. Yikeshan Yalikun, Isaac Prah, Samiratu Mahazu, Yusuke Ota, Ryoichi Saito. Genomic and population insight of ESBL-producing Klebsiella pneumoniae from Ghana. 第34回日本臨床微生物学会総会・学術集会 2023.02.03

  7. Yusuke Ota, Reina Okada, Hideyuki Takahashi, Ryoichi Saito. Rapid and simple PCR-RFLP assay for detecting a mutation at codon 91 of gyrA in Neisseria meningitidis. The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine（ASCPaLM） 2022.10.09

  8. Yikeshan Yalikun, Isaac Prah, Samiratu Mahazu, Yusuke Ota, Anthony Ablordey, Ryoichi Saito. Characterization of extended-spectrum β-lactamase producing Klebsiella pneumoniae from Ghana. The 17th Congress of Asian Society for Clinical Pathology and Laboratory Medicine 2022.10.09

  9. Taira Kawamura, Akari Samejima, Yukino Usui, Issac Prah, Samiratu Mahazu, Yusuke Ota, Ryoichi Saito. Role of cyclic-di-AMP phosphodiesterase on vancomycin susceptibility and growth in Clostridioides difficile. The 17th Congress of Asian Society for Clinical Pathology and Laboratory Medicine 2022.10.09

  10. Kayo Yamada, Alafate Ayibieke, Samiratu Mahazu, Isaac Prah, Yusuke Ota, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito. Genetic and phenotypic features of Staphylococcus epidermidis ST2 bloodstream isolates from Tokyo. The 17th Congress of Asian Society for Clinical Pathology and Laboratory Medicine 2022.10.09

  11. Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito. Klebsiella species and Enterobacter cloacae isolates harbouring blaOXA-181 and blaOXA-48: resistome, fitness cost, and plasmid stability. The 17th Congress of Asian Society for Clinical Pathology and Laboratory Medicine 2022.10.09

  12. Y Nukui, Y Ota, I Prah, R Saito, Y Aiso, M Sugii, S Kanehira, J Nakajima, K Sonobe, S Tohda, R Koike, Y Gu. Molecular Epidemiological Analysis of Third Generation Cephalosporin and Piperacillin/Tazobactam-Resistant Klebsiella oxytoca, Which Caused an Outbreak in a COVID-19 Intensive Care Unit. ASM Microbe 2022.06.10 Washington, DC

  13. Kayo Yamada, Alafate Ayibieke, Samiratu Mahazu, Isaac Prah, Yusuke Ota, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito. Novel insights and genetic features of Staphylococcus epidermidis bloodstream isolates from Tokyo. ASM Microbe 2022.06.10

  14. Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito. Molecular characterization of Klebsiella pneumoniae and Enterobacter cloacae isolates harboring blaOXA-181 and blaOXA-48. ASM Microbe 2022.06.10

  15. Ota Y, Furuhashi K, Nanba T, Yamanaka K, Ishikawa J, Nagura O, Hamada E, Maekawa M. Loop-mediated Isothermal Amplification-based Antimicrobial Susceptibility Testing in Escherichia coli. The 57th Congress of the Korean Association of Medical Technologists International Conference 2019

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