Personnel Information

写真a

SHIMIZU Masaki


Job title

Junior Associate Professor

Homepage URL

http://www.tmd.ac.jp/med/ped/en/

Research Areas, Keywords

Pediatric Rheumatology, Pediatric Nephrology, Clinical Immunology

Graduating School 【 display / non-display

  • Kanazawa University, Faculty of Medicine, 1998.03, Graduated

Graduate School 【 display / non-display

  • Kanazawa University, Graduate School, Division of Medical Sciences, Doctor's Course, 2005.03, Completed

Campus Career 【 display / non-display

  • 2020.04
    -
    2022.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Child Health and Development, Junior Associate Professor
  • 2020.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Pediatrics and Developmental Biology, Junior Associate Professor
  • 2022.10
    -
    Now
    Tokyo Medical and Dental University, Tokyo Medical and Dental University, Division of Clinical Medicine, Department of Pediatrics, Perinatal, and Women's Medicine, Pediatrics, Junior Associate Professor

External Career 【 display / non-display

  • 2005.08
    -
    2007.06
    , postdoctoral fellow
  • 2007.09
    -
    2018.03
    , Assistant Professor
  • 2012.09
    -
    2012.11
    , JCR-EULAR young rheumatologist training program
  • 2018.04
    -
    2020.03
    , Junior Associate Professor

Research Areas 【 display / non-display

  • Embryonic medicine and pediatrics

 

Published Papers & Misc 【 display / non-display

  1. Saki Kanda, Asami Shimbo, Yoshitaka Nakamura, Ryosuke Matsuno, Shuya Kaneko, Hitoshi Irabu, Kazunari Kaneko, Masaki Shimizu. Anti-Ku antibody-positive systemic sclerosis and idiopathic inflammatory myopathies overlap syndrome in children: a report of two cases and a review of the literature. Clin Rheumatol. 2023.12; 42 (12): 3411-3417. ( PubMed, DOI )

  2. Shuya Kaneko, Yusuke Noguchi, Maho Hatano, Asami Shimbo, Hitoshi Irabu, Kenji Furuno, Naomi Iwata, Junya Fujimura, Keiji Akamine, Anna Kobayashi, Takuya Endo, Tomohiro Morio, Masaki Shimizu. Clinical Usefulness of T-Cell Receptor Vβ Repertoire Analysis for Differentiating Multisystem Inflammatory Syndrome in Japanese Children From Toxic Shock Syndrome and Kawasaki Disease. Pediatr Infect Dis J. 2023.12; ( PubMed, DOI )

  3. Takuji Itakura, Hirokazu Sasaki, Tadashi Hosoya, Taiki Yamaguchi, Erika Mimori, Yukino Saimon, Hideyuki Iwai, Natsuka Umezawa, Daisuke Kawata, Naoki Kimura, Morito Kurata, Masaki Shimizu, Shinsuke Yasuda. A novel gain-of-function missense variant in PLCG2 associated with autoinflammation and hypergammaglobulinaemia. Rheumatology (Oxford). 2023.11; 62 (11): e319-e321. ( PubMed, DOI )

  4. Shuya Kaneko, Masaki Shimizu, Asami Shimbo, Hitoshi Irabu, Koji Yokoyama, Kenji Furuno, Takayuki Tanaka, Kazuyuki Ueno, Shuhei Fujita, Naomi Iwata, Junya Fujimura, Keiji Akamine, Mao Mizuta, Yasuo Nakagishi, Toshinori Minato, Kenichi Watanabe, Anna Kobayashi, Takuya Endo, Katsuhiko Tabata, Masaaki Mori, Tomohiro Morio. Clinical significance of serum cytokine profiles for differentiating between Kawasaki disease and its mimickers. Cytokine. 2023.09; 169 156280. ( PubMed, DOI )

  5. Ramanan AV, Quartier P, Okamoto N, Foeldvari I, Spindler A, Fingerhutová Š, Antón J, Wang Z, Meszaros G, Araújo J, Liao R, Keller S, Brunner HI, Ruperto N; JUVE-BASIS investigators; Paediatric Rheumatology International Trials Organisation. Diego Viola, Alberto Spindler, Jonathan Akikusa, Jeffrey Chaitow, Christian Huemer, Joke Dehoorne, Carine Wouters, Bernard Lauwerys, Cecile Boulanger, Claudia Saad Magalhães, Maria Terreri, Caifeng Li, Xuemei Tang, Qihua Feng, Haiguo Yu, Zhixuan Zhou, Pavla Dolezalova, Rudolf Horvath, Troels Herlin, Mia Glerup, Pierre Quartier Dit Maire, Isabelle Kone Paut, Elisabeth Gervais, Alexandre Belot, Investigator Name, Gerd Horneff, Kirsten Minden, Ralf Trauzeddel, Ivan Foeldvari, Thomas Lutz, Astrid Helling-Bakki, Jürgen Grulich-Henn, Jasmin Kümmerle-Deschner, Sujata Sawhney, Sathish Kumar, Mahesh Janarthanan, Gil Amarilyo, Yonatan Butbul, Yosef Uziel, Irit Tirosh, Liora Harel, Roberta Caorsi, Serena Pastore, Alberto Tommasini, Maria Alessio, Luciana Breda, Marco Cattalini, Rolando Cimaz, Teresa Giani, Gabriele Simonini, Giovanni Filocamo, Hiroaki Umebayashi, Utako Kaneko, Yutaka Kawano, Satoshi Sato, Masaaki Mori, Masaki Shimizu, Kenichi Yamaguchi, Shuichi Ito, Tomoyuki Imagawa, Masaki Shimizu, Natsumi Inoue, Tadafumi Yokoyama, Kosuke Shabana, Yuka Ozeki, Yoshifumi Kawano, Yuichi Yamasaki, Takako Miyamae, Gabriel Vega Cornejo, Nadina Rubio Perez, Edgar Vargas, Cesar Pacheco-Tena, Favio Edmundo Enriquez Sosa, Elzbieta Smolewska, Zbigniew Zuber, Piotr Gietka, Ekaterina Alexeeva, Irina Nikishina, Sania Valieva, Jordi Antón López, Sara Murias Loza, Rosa Maria Alcobendas Rueda, Inmaculada Calvo Penades, Genaro Grana, Alina Lucica Boteanu, Ozgur Kasapcopur, Erbil Unsal, Athimalaipet Vaidyanathan Ramanan, Sandrine Lacassagne, Daniel Hawley, Kamran Mahmood, Beverley Almeida and thePaediatric Rheumatology International Trials Organisation. . Baricitinib in juvenile idiopathic arthritis: an international, phase 3, randomised, double-blind, placebo-controlled, withdrawal, efficacy, and safety trial. Lancet. 2023.08; 402 (10401): 555-570. ( PubMed, DOI )

  6. Yamamoto Keiko Shimojima, Tamura Takeaki, Okamoto Nobuhiko, Nishi Eriko, Noguchi Atsuko, Takahashi Ikuko, Sawaishi Yukio, Shimizu Masaki, Kanno Hitoshi, Minakuchi Yohei, Toyoda Atsushi, Yamamoto Toshiyuki. Identification of small-sized intrachromosomal segments at the ends of INV-DUP-DEL patterns JOURNAL OF HUMAN GENETICS. 2023.07; ( PubMed, DOI )

  7. Mariko Mouri, Toru Kanamori, Eriko Tanaka, Kanako Hiratoko, Mariko Okubo, Michio Inoue, Tomohiro Morio, Masaki Shimizu, Ichizo Nishino, Naoko Okiyama, Masaaki Mori. Hepatic veno-occlusive disease accompanied by thrombotic microangiopathy developed during treatment of juvenile dermatomyositis and macrophage activation syndrome: A case report. Mod Rheumatol Case Rep. 2023.06; 7 (2): 404-409. ( PubMed, DOI )

  8. Mao Mizuta, Natsumi Inoue, Masaki Shimizu, Naoto Sakumura, Tadafumi Yokoyama, Rie Kuroda, Yasuhiro Ikawa, Naotoshi Sugimoto, Kenichi Harada, Akihiro Yachie, Taizo Wada. Distinct roles of IL-18 and IL-1β in murine model of macrophage activation syndrome. J Allergy Clin Immunol. 2023.06; ( PubMed, DOI )

  9. Ryosuke Wakatsuki, Yoshiho Hatai, Kentaro Okamoto, Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Masaki Shimizu, Hirokazu Kanegane, Makoto Ono. An infant with A20 haploinsufficiency presenting with periodic fever syndrome: A case report. Int J Rheum Dis. 2023.05; 26 (5): 973-976. ( PubMed, DOI )

  10. Masaki Shimizu, Kenichi Nishimura, Naomi Iwata, Takahiro Yasumi, Hiroaki Umebayashi, Yasuo Nakagishi, Yuka Okura, Nami Okamoto, Noriko Kinjo, Mao Mizuta, Masato Yashiro, Junko Yasumura, Hiroyuki Wakiguchi, Tomohiro Kubota, Mariko Mouri, Utako Kaneko, Masaaki Mori. Treatment for macrophage activation syndrome associated with systemic juvenile idiopathic arthritis in Japan. Int J Rheum Dis. 2023.05; 26 (5): 938-945. ( PubMed, DOI )

  11. Shuya Kaneko, Masaki Shimizu, Futaba Miyaoka, Asami Shimbo, Hitoshi Irabu, Mao Mizuta, Yasuo Nakagishi, Naomi Iwata, Junya Fujimura, Masaaki Mori, Tomohiro Morio. The dynamics of laboratory markers reflecting cytokine overproduction in macrophage activation syndrome complicated with systemic juvenile idiopathic arthritis. Clin Immunol. 2023.03; 248 109270. ( PubMed, DOI )

  12. Kento Souma, Junya Fujimura, Atushi Nishiyama, Yoshinobu Oyazato, Shuya Kaneko, Masaki Shimizu, Takeshi Morisawa. Serum interleukin-18 level as a possible early diagnostic marker of systemic juvenile idiopathic arthritis. Int J Rheum Dis. 2023.03; 26 (3): 551-553. ( PubMed, DOI )

  13. Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Toshiyuki Yamamoto, Masaki Shimizu. Inverted-duplication-deletion of chromosome 10q identified in a patient with systemic lupus erythematosus. Pediatr Int. 2023.01; 65 (1): e15396. ( PubMed, DOI )

  14. Irabu H, Shimizu M. A Bone-on-Bone Appearance in Chronic Nonbacterial Osteomyelitis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2023.01; 29 (1): e5. ( PubMed, DOI )

  15. Masaki Shimizu, Hitoshi Irabu, Asami Shimbo, Shuya Kaneko, Masaaki Mori. Monthly intravenous immunoglobulin for refractory intestinal IgA vasculitis. Pediatr Int. 2023.01; e15470. ( PubMed, DOI )

  16. Ryosuke Wakatsuki, Masaki Shimizu, Asami Shimbo, Eriko Adachi, Toru Kanamori, Susumu Yamazaki, Tomohiro Udagawa, Kei Takasawa, Kenichi Kashimada, Tomohiro Morio, Masaaki Mori. Atrophic autoimmune thyroiditis complicated with systemic lupus erythematosus. Mod Rheumatol Case Rep. 2023.01; 7 (1): 65-67. ( PubMed, DOI )

  17. Kaneko Shuya, Shimizu Masaki, Shimbo Asami, Irabu Hitoshi, Yamazaki Susumu, Kanamori Toru, Udagawa Tomohiro, Morio Tomohiro, Mori Masaaki. A girl with hearing loss, dizziness, hypertension, and pyelonephritis with ureteral edema: Questions PEDIATRIC NEPHROLOGY. 2022.12; 37 (12): 3057-3058. ( PubMed, DOI )

  18. Shuya Kaneko, Masaki Shimizu, Asami Shimbo, Hitoshi Irabu, Susumu Yamazaki, Toru Kanamori, Tomohiro Udagawa, Tomohiro Morio, Masaaki Mori. A girl with hearing loss, dizziness, hypertension, and pyelonephritis with ureteral edema: Answers Pediatr Nephrol. 2022.12; 37 (12): 3059-3061. ( PubMed, DOI )

  19. Daiki Niizato, Takeshi Isoda, Noriko Mitsuiki, Shuya Kaneko, Dan Tomomasa, Takahiro Kamiya, Masatoshi Takagi, Kohsuke Imai, Michiko Kajiwara, Masaki Shimizu, Tomohiro Morio, Hirokazu Kanegane. Case report: Optimized ruxolitinib-based therapy in an infant with familial hemophagocytic lymphohistiocytosis type 3. Front Immunol. 2022.11; 13 977463. ( PubMed, DOI )

  20. Naomi Iwata, Kenichi Nishimura, Ryoki Hara, Tomoyuki Imagawa, Masaki Shimizu, Minako Tomiita, Hiroaki Umebayashi, Syuji Takei, Noriko Seko, Ryota Wakabayashi, Shumpei Yokota. Long-term Efficacy and Safety of Canakinumab in the Treatment of Systemic Juvenile Idiopathic Arthritis in Japanese Patients: Results from an Open-label Phase III Study. Mod Rheumatol. 2022.11; ( PubMed, DOI )

  21. Niwano Tomoko, Hosoya Tadashi, Kadowaki Saori, Toyofuku Etsushi, Naruto Takuya, Shimizu Masaki, Ohnishi Hidenori, Koike Ryuji, Morio Tomohiro, Imai Kohsuke, Yoshida Masayuki, Yasuda Shinsuke. An adult case of suspected A20 haploinsufficiency mimicking polyarteritis nodosa RHEUMATOLOGY. 2022.11; 61 (11): E337-E340. ( PubMed, DOI )

  22. Tanabe Y, Ota H, Kaneko S, Tsuno K, Watanabe M, Yamanishi S, Narazaki H, Fukazawa R, Shimizu M, Itoh Y. Clinical course and cytokine analysis of a systemic juvenile idiopathic arthritis patient with trisomy 21. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2022.10; ( PubMed, DOI )

  23. Asami Shimbo, Masaki Shimizu, Shuya Kaneko, Hitoshi Irabu, Tomohiro Morio. Clinical Significance of Vascular Ultrasonography in the Diagnosis of Early Childhood Takayasu Arteritis Presenting as Fever of Unknown Origin. J Paediatr Child Health. 2022.10; 58 (10): 1910-1911. ( PubMed, DOI )

  24. Miyamoto Takayuki, Honda Yoshitaka, Izawa Kazushi, Kanazawa Nobuo, Kadowaki Saori, Ohnishi Hidenori, Fujimoto Masakazu, Kambe Naotomo, Kase Naoya, Shiba Takeshi, Nakagishi Yasuo, Akizuki Shuji, Murakami Kosaku, Bamba Masahiro, Nishida Yutaka, Inui Ayano, Fujisawa Tomoo, Nishida Daisuke, Iwata Naomi, Otsubo Yoshikazu, Ishimori Shingo, Nishikori Momoko, Tanizawa Kiminobu, Nakamura Tomoyuki, Ueda Takeshi, Ohwada Yoko, Tsuyusaki Yu, Shimizu Masaki, Ebato Takasuke, Iwao Kousho, Kubo Akiharu, Kawai Toshinao, Matsubayashi Tadashi, Miyazaki Tatsuhiko, Kanayama Tomohiro, Nishitani-Isa Masahiko, Nihira Hiroshi, Abe Junya, Tanaka Takayuki, Hiejima Eitaro, Okada Satoshi, Ohara Osamu, Saito Megumu K., Takita Junko, Nishikomori Ryuta, Yasumi Takahiro. Assessment of type I interferon signatures in undifferentiated inflammatory diseases: A Japanese multicenter experience FRONTIERS IN IMMUNOLOGY. 2022.09; 13 905960. ( PubMed, DOI )

  25. Shimizu Masaki, Takei Syuji, Mori Masaaki, Yachie Akihiro. Pathogenic roles and diagnostic utility of interleukin-18 in autoinflammatory diseases FRONTIERS IN IMMUNOLOGY. 2022.09; 13 951535. ( PubMed, DOI )

  26. Higuchi Toru, Izawa Kazushi, Miyamoto Takayuki, Honda Yoshitaka, Nishiyama Atsuko, Shimizu Masaki, Takita Junko, Yasumi Takahiro. An efficient diagnosis: A patient with X-linked inhibitor of apoptosis protein (XIAP) deficiency in the setting of infantile hemophagocytic lymphohistiocytosis was diagnosed using high serum interleukin-18 combined with common laboratory parameters PEDIATRIC BLOOD & CANCER. 2022.08; 69 (8): e29606. ( PubMed, DOI )

  27. Susumu Yamazaki, Masaki Shimizu, Yuko Akutsu, Asami Shimbo, Masaaki Mori. Tacrolimus as an alternative treatment for patients with juvenile idiopathic arthritis. Mod Rheumatol. 2022.07; 32 (4): 783-791. ( PubMed, DOI )

  28. Shimizu Masaki, Shimbo Asami, Irabu Hitoshi, Inoue Natsumi, Kuroda Mondo. Hirayama disease JOINT BONE SPINE. 2022.07; 89 (4): 105354. ( PubMed, DOI )

  29. Kazumoto Iijima, Mayumi Sako, Mari Oba, Seiji Tanaka, Riku Hamada, Tomoyuki Sakai, Yoko Ohwada, Takeshi Ninchoji, Tomohiko Yamamura, Hiroyuki Machida, Yuko Shima, Ryojiro Tanaka, Hiroshi Kaito, Yoshinori Araki, Tamaki Morohashi, Naonori Kumagai, Yoshimitsu Gotoh, Yohei Ikezumi, Takuo Kubota, Koichi Kamei, Naoya Fujita, Yasufumi Ohtsuka, Takayuki Okamoto, Takeshi Yamada, Eriko Tanaka, Masaki Shimizu, Tomoko Horinouchi, Akihide Konishi, Takashi Omori, Koichi Nakanishi, Kenji Ishikura, Shuichi Ito, Hidefumi Nakamura, Kandai Nozu, . Mycophenolate Mofetil after Rituximab for Childhood-Onset Complicated Frequently-Relapsing or Steroid-Dependent Nephrotic Syndrome. J Am Soc Nephrol. 2022.02; 33 (2): 401-419. ( PubMed, DOI )

  30. Masaki Shimizu, Asami Shimbo, Susumu Yamazaki, Yuko Segawa, Masaaki Mori. Septic arthritis of the pubic symphysis in a patient with SLE. Pediatr Int. 2022.01; 64 (1): e14875. ( PubMed, DOI )

  31. Yamaguchi Y, Takasawa K, Irabu H, Hiratoko K, Ichigi Y, Hirata K, Tamura Y, Murakoshi M, Yamashita M, Nakatani H, Shimoda M, Ishii T, Udagawa T, Shimizu M, Kanegane H, Morio T. Infliximab treatment for refractory COVID-19-associated multisystem inflammatory syndrome in a Japanese child. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022.01; ( PubMed, DOI )

  32. Susumu Yamazaki, Asami Shimbo, Takahiro Kamiya, Masaki Shimizu, Masaaki Mori. Ankylosing spondylitis, Crohn's disease, and myelodysplasia in an adolescent. Pediatr Int. 2022.01; 64 (1): e15215. ( PubMed, DOI )

  33. Hatano Maho, Shimizu Masaki, Miyaoka Futaba, Kanai Hozumi, Nishioka Masato. Microgeodic disease with multiple skin ulcers PEDIATRICS INTERNATIONAL. 2022.01; 64 (1): e15013. ( PubMed, DOI )

  34. Hoshi Yurika, Shimizu Masaki, Shimbo Asami, Yamazaki Susumu, Mori Masaaki. Overt myositis in a girl with systemic lupus erythematosus PEDIATRICS INTERNATIONAL. 2022.01; 64 (1): e15338. ( PubMed, DOI )

  35. Shimizu Masaki. 全身性若年性特発性関節炎におけるマクロファージ活性化症候群(Macrophage activation syndrome in systemic juvenile idiopathic arthritis) Immunological Medicine. 2021.12; 44 (4): 237-245. ( ichushi )

  36. Shimizu Masaki, Shimbo Asami, Yamazaki Susumu, Mori Masaaki. Concurrent lupus enteritis and cystitis PEDIATRICS INTERNATIONAL. 2021.09; 63 (9): 1142-1143. ( PubMed, DOI )

  37. Asami Shimbo, Yuko Akutsu, Susumu Yamazaki, Masaki Shimizu, Masaaki Mori. Giant Iliopsoas Bursitis in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2021.07; 73 (7): 1328. ( PubMed, DOI )

  38. Masaki Shimizu, Asami Shimbo, Masatoshi Takagi, Katsuhide Eguchi, Masataka Ishimura, Junichi Sugita, Tomohiro Morio, Hirokazu Kanegane. Successful treatment of joint and fascial chronic graft-versus-host disease with baricitinib. Rheumatology (Oxford). 2021.07; ( PubMed, DOI )

  39. Shimizu M. Macrophage activation syndrome in systemic juvenile idiopathic arthritis. Immunological medicine. 2021.05; 1-9. ( PubMed, DOI )

  40. Fujita Yuji, Sato Yuya, Takagi Yuhi, Nakazato Yoshimasa, Shimizu Masaki, Mori Masaaki, Yoshihara Shigemi. Hemophagocytic lymphohistiocytosis associated with primary cutaneous gamma-delta T-cell lymphoma presenting with subcutaneous panniculitis in a 12-year-old girl PEDIATRIC BLOOD & CANCER. 2021.03; e29035. ( PubMed, DOI )

  41. Tasaki Y, Inoue N, Shimizu M, Sugimoto N, Ishikawa S, Mizuta M, Yokoyama T, Kuroda M, Ohta K, Yachie A, Wada T. Serum insulin-like growth factor-binding protein 2 levels as an indicator for disease severity in enterohemorrhagic <i>Escherichia coli</i> induced hemolytic uremic syndrome. Renal failure. 2021.03; 43 (1): 382-387. ( PubMed, DOI )

  42. Hitoshi Irabu, Masaki Shimizu, Shuya Kaneko, Natsumi Inoue, Mao Mizuta, Yuko Tasaki, Kazuhide Ohta, Akihiro Yachie, Taizo Wada. Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis. Pediatr Res. 2021.02; 89 (3): 667-672. ( PubMed, DOI )

  43. Masaki Shimizu, Natsumi Inoue, Mao Mizuta, Hitoshi Irabu, Michiko Okajima, Yoshitaka Honda, Hiroshi Nihira, Kazushi Izawa, Akihiro Yachie, Taizo Wada. Successful treatment of spondyloenchondrodysplasia with baricitinib. Rheumatology (Oxford). 2021.02; 60 (2): e44-e46. ( PubMed, DOI )

  44. Hayashi H, Uda K, Akamine K, Kawata N, Akahoshi S, Shimizu M, Horikoshi Y, Hataya H. A 15-Month-old Boy With Kawasaki Disease-like Symptoms. The Pediatric infectious disease journal. 2021.02; 40 (2): 173-174. ( PubMed, DOI )

  45. Yamazaki S, Akutsu Y, Shimbo A, Shimizu M, Segawa Y, Mori M. Childhood-onset systemic lupus erythematosus with trisomy X and the increased risk for bone complications: a case report. Pediatric rheumatology online journal. 2021.02; 19 (1): 20. ( PubMed, DOI )

  46. Mao Mizuta, Masaki Shimizu, Hitoshi Irabu, Masaaki Usami, Natsumi Inoue, Yasuo Nakagishi, Taizo Wada, Akihiro Yachie. Comparison of serum cytokine profiles in macrophage activation syndrome complicating different background rheumatic diseases in children. Rheumatology (Oxford). 2021.01; 60 (1): 231-238. ( PubMed, DOI )

  47. Kenichi Nishimura, Ryoki Hara, Hiroaki Umebayashi, Syuji Takei, Naomi Iwata, Tomoyuki Imagawa, Masaki Shimizu, Minako Tomiita, Noriko Seko, Tetsuji Kitawaki, Shumpei Yokota. Efficacy and safety of canakinumab in systemic juvenile idiopathic arthritis: 48-week results from an open-label phase III study in Japanese patients. Mod Rheumatol. 2021.01; 31 (1): 226-234. ( PubMed, DOI )

  48. Yamanouchi S, Yamagishi M, Kaneko S, Shimizu M, Kaneko K. Dysregulation of angiopoietin-1 and angiopoietin-2 in an infant with fatal Clarkson disease. Pediatrics international : official journal of the Japan Pediatric Society. 2020.12; 62 (12): 1400-1401. ( PubMed, DOI )

  49. Jessica Tibaldi, Angela Pistorio, Elena Aldera, Laura Puzone, Yasser El Miedany, Priyankar Pal, Prabhas Prasun Giri, Hriday De, Raju Khubchandani, Pallavi Pimpale Chavan, Soamarat Vilaiyuk, Butsabong Lerkvaleekul, Jutamas Yamsuwan, Tapas K Sabui, Pragati Datta, Manuela Pardeo, Claudia Bracaglia, Sujata Sawhney, Sumidha Mittal, Waleed A Hassan, Ghada Farouk Elderiny, Mohammed Hassan Abu-Zaid, Mervat Eissa, Flavio Sztajnbok, Fernanda C das Neves Sztajnbok, Ricardo Russo, María Martha Katsicas, Rolando Cimaz, Edoardo Marrani, Ekaterina Alexeeva, Tatyana M Dvoryakovskaya, Motasem O Alsuweiti, Ra'ed M Alzyoud, Mikhail Kostik, Irina Chikova, Francesca Minoia, Giovanni Filocamo, Yomna Farag, Hala Lotfy, Samah Ismail Nasef, Sulaiman M Al-Mayouf, Maria Cristina Maggio, Claudia Saad Magalhaes, Romina Gallizzi, Giovanni Conti, Masaki Shimizu, Adele Civino, Enrico Felici, Gabriella Giancane, Nicolino Ruperto, Alessandro Consolaro, Angelo Ravelli. Development and initial validation of a composite disease activity score for systemic juvenile idiopathic arthritis. Rheumatology (Oxford). 2020.11; 59 (11): 3505-3514. ( PubMed, DOI )

  50. Mizuta M, Shimizu M, Inoue N, Ikawa Y, Nakagishi Y, Yasuoka R, Iwata N, Yachie A. Clinical significance of interleukin-18 for the diagnosis and prediction of disease course in systemic juvenile idiopathic arthritis. Rheumatology (Oxford, England). 2020.11; ( PubMed, DOI )

  51. Tsukasa Tanaka, Masaki Shimizu, Oshi Tokuda, Hiroko Yamamoto, Natsuki Matsunoshita, Kanae Takenaka, Keiichiro Kawasaki. Kawasaki Disease with an Initial Manifestation Mimicking Bacterial Inguinal Cellulitis Case Reports in Pediatrics. 2020.10;

  52. Inoue N, Shimizu M, Mizuta M, Yachie A. Successful treatment of tumor necrosis factor inhibitor-resistant cutaneous polyarteritis nodosa with tocilizumab. Pediatrics international : official journal of the Japan Pediatric Society. 2020.06; 62 (6): 753-755. ( PubMed, DOI )

  53. Inoue Natsumi, Shimizu Masaki, Mizuta Mao, Yachie Akihiro. TNF阻害薬抵抗性の皮膚型結節性多発動脈炎に対して奏効したトシリズマブ投与(Successful treatment of tumor necrosis factor inhibitor-resistant cutaneous polyarteritis nodosa with tocilizumab) Pediatrics International. 2020.06; 62 (6): 753-755. ( ichushi )

  54. Kaneko S, Shimizu M, Inoue N, Mizuta M, Yachie A. Chronic recurrent multifocal osteomyelitis with myositis: A case report and review of the literature. Pediatrics international : official journal of the Japan Pediatric Society. 2020.05; 62 (5): 644-645. ( PubMed, DOI )

  55. Kaneko Shuya, Shimizu Masaki, Inoue Natsumi, Mizuta Mao, Yachie Akihiro. 筋炎を伴う慢性再発性多発性骨髄炎 症例報告と文献レビュー(Chronic recurrent multifocal osteomyelitis with myositis: A case report and review of the literature) Pediatrics International. 2020.05; 62 (5): 644-645. ( ichushi )

  56. Shimizu M, Inoue N, Mizuta M, Sakakibara Y, Hamaguchi Y, Yachie A. Periorbital Edema as the Initial Sign of Juvenile Dermatomyositis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2020.04; 26 (3): e61. ( PubMed, DOI )

  57. Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis during tocilizumab therapy. Pediatric research. 2020.03; ( PubMed, DOI )

  58. Shimizu M. Pathogenic functions and diagnostic utility of cytokines/chemokines in EHEC-HUS. Pediatrics international : official journal of the Japan Pediatric Society. 2020.03; 62 (3): 308-315. ( PubMed, DOI )

  59. Shimizu Masaki. EHEC-HUSにおけるサイトカイン/ケモカインの病原性機能と診断的有用性(Pathogenic functions and diagnostic utility of cytokines/chemokines in EHEC-HUS) Pediatrics International. 2020.03; 62 (3): 308-315. ( ichushi )

  60. Shimizu M, Shimizu H, Jinkawa A, Yamamiya M, Shinozaki E, Yokoyama T, Ohta K, Sakumura N, Takakuwa M, Fujita S, Fusagawa S, Nakagishi Y, Nariai E, Yachie A. Cytokine Profiles in Human Parechovirus Type 3-induced Sepsis-like Syndrome. The Pediatric infectious disease journal. 2020.02; 39 (2): 137-139. ( PubMed, DOI )

  61. Sakumura N, Irabu H, Inoue N, Mizuta M, Shimizu M. Clinical usefulness of longitudinal IL-6 monitoring in a patient with Takayasu aortitis receiving tocilizumab. Rheumatology . 2020.01; 59 (1): 252-254. ( PubMed, DOI )

  62. Shimizu Masaki, Mizuta Mao, Okamoto Nami, Yasumi Takahiro, Iwata Naomi, Umebayashi Hiroaki, Okura Yuka, Kinjo Noriko, Kubota Tomohiro, Nakagishi Yasuo, Nishimura Kenichi, Mohri Mariko, Yashiro Masato, Yasumura Junko, Wakiguchi Hiroyuki, Mori Masaaki. Tocilizumab modifies clinical and laboratory features of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis PEDIATRIC RHEUMATOLOGY. 2020.01; 18 (1): 2. ( PubMed, DOI )

  63. Irabu H, Shimizu M, Kaneko S, Inoue N, Mizuta M, Ohta K, Yachie A. Clinical Significance of Serum Galactose-Deficient IgA1 Level in Children with IgA Nephropathy. Journal of immunology research. 2020; 2020 4284379. ( PubMed, DOI )

  64. Yasumura J, Shimizu M, Toma T, Yashiro M, Yachie A, Okada S. Clinical Significance of Serum Soluble TNF Receptor I/II Ratio for the Differential Diagnosis of Tumor Necrosis Factor Receptor-Associated Periodic Syndrome From Other Autoinflammatory Diseases. Frontiers in immunology. 2020; 11 576152. ( PubMed, DOI )

  65. Tanaka T, Shimizu M, Tokuda O, Yamamoto H, Matsunoshita N, Takenaka K, Kawasaki K. Kawasaki Disease with an Initial Manifestation Mimicking Bacterial Inguinal Cellulitis. Case reports in pediatrics. 2020; 2020 8889827. ( PubMed, DOI )

  66. Takakura M, Shimizu M, Irabu H, Sakumura N, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Clinical immunology (Orlando, Fla.). 2019.11; 208 108252. ( PubMed, DOI )

  67. Usami M, Shimizu M, Mizuta M, Inoue N, Irabu H, Sakumura N, Nakagishi Y, Yachie A. Extensive serum biomarker analysis in patients with macrophage activation syndrome associated with systemic lupus erythematosus. Clinical immunology (Orlando, Fla.). 2019.11; 208 108255. ( PubMed, DOI )

  68. Shimizu M, Kizawa T, Kato R, Suzuki T, Yachie A. Macrophage activation syndrome in neonates born to mothers with adult-onset Still's disease: Perinatal effect of maternal IL-18. Clinical immunology (Orlando, Fla.). 2019.10; 207 36-39. ( PubMed, DOI )

  69. Kaneko S, Shimizu M, Irabu H, Yachie A. Acute generalized exanthematous pustulosis in a child with fasciitis. Pediatrics international : official journal of the Japan Pediatric Society. 2019.09; 61 (9): 938. ( PubMed, DOI )

  70. Kaneko Shuya, Shimizu Masaki, Irabu Hitoshi, Yachie Akihiro. 筋膜炎小児における急性汎発性発疹性膿疱症(Acute generalized exanthematous pustulosis in a child with fasciitis) Pediatrics International. 2019.09; 61 (9): 938. ( ichushi )

  71. Mizuta M, Shimizu M, Inoue N, Nakagishi Y, Yachie A. Clinical significance of serum CXCL9 levels as a biomarker for systemic juvenile idiopathic arthritis associated macrophage activation syndrome. Cytokine. 2019.07; 119 182-187. ( PubMed, DOI )

  72. Jinkawa A, Shimizu M, Nishida K, Kaneko S, Usami M, Sakumura N, Irabu H, Takakuwa M, Inoue N, Mizuta M, Ikawa Y, Fujita S, Yachie A. Cytokine profile of macrophage activation syndrome associated with Kawasaki disease. Cytokine. 2019.07; 119 52-56. ( PubMed, DOI )

  73. Shimizu M, Irabu H, Kaneda H, Ohta K, Nozu K. Familial focal segmental glomerulosclerosis with PLCE1 mutation in siblings. Pediatrics international : official journal of the Japan Pediatric Society. 2019.07; 61 (7): 726-727. ( PubMed, DOI )

  74. Shimizu Masaki, Irabu Hitoshi, Kaneda Hisashi, Ohta Kazuhide, Nozu Kandai. 同胞で認められたPLCE1変異を伴う家族性巣状分節性糸球体硬化症(Familial focal segmental glomerulosclerosis with PLCE1 mutation in siblings) Pediatrics International. 2019.07; 61 (7): 726-727. ( ichushi )

  75. Ono R, Shimizu M, Yamamoto K, Umehara N, Manabe A. Kawasaki disease shock syndrome: Case report and cytokine profiling. Pediatrics international : official journal of the Japan Pediatric Society. 2019.06; 61 (6): 620-622. ( PubMed, DOI )

  76. Shimizu Masaki, Mizuta Mao, Yasumi Takahiro, Iwata Naomi, Okura Yuka, Kinjo Noriko, Umebayashi Hiroaki, Kubota Tomohiro, Nakagishi Yasuo, Nishimura Kenichi, Yashiro Masato, Yasumura Junko, Wakiguchi Hiroyuki, Okamoto Nami, Mori Masaaki. TOCILIZUMAB MODIFIES CLINICAL MANIFESTATIONS AND LABORATORY FEATURES OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS ASSOCIATED MACROPHAGE ACTIVATION SYNDROME ANNALS OF THE RHEUMATIC DISEASES. 2019.06; 78 1989. ( DOI )

  77. Ono Rintaro, Shimizu Masaki, Yamamoto Kaoru, Umehara Naoki, Manabe Atsushi. 川崎病ショック症候群 1症例報告およびサイトカインプロファイリング(Kawasaki disease shock syndrome: Case report and cytokine profiling) Pediatrics International. 2019.06; 61 (6): 620-622. ( ichushi )

  78. Yokoyama Tadafumi, Takemura Yuta, Taniguchi Chihiro, Jinkawa Asumi, Yamamiya Mari, Obata Misato, Miyashita Kengo, Inoue Mika, Sakazume Shinobu, Ohta Kazuhide, Irabu Hitoshi, Inoue Natsumi, Shimizu Masaki. 膿尿や細菌尿を伴わない急性腎盂腎炎の臨床的特徴(Clinical characteristics of the acute pyelonephritis without pyuria or bacteriuria) 日本小児腎臓病学会雑誌. 2019.05; 32 (1Suppl.): 187. ( ichushi )

  79. Yasumura Junko, Yashiro Masato, Okamoto Nami, Shabana Kosuke, Umebayashi Hiroaki, Iwata Naomi, Okura Yuka, Kubota Tomohiro, Shimizu Masaki, Tomiita Minako, Nakagishi Yasuo, Nishimura Kenichi, Hara Ryoki, Mizuta Mao, Yasumi Takahiro, Yamaide Fumiya, Wakiguchi Hiroyuki, Kobayashi Masao, Mori Masaaki. Clinical features and characteristics of uveitis associated with juvenile idiopathic arthritis in Japan: first report of the pediatric rheumatology association of Japan (PRAJ) PEDIATRIC RHEUMATOLOGY. 2019.04; 17 (1): 15. ( PubMed, DOI )

  80. Yamada S, Shimizu M, Kuroda M, Inoue N, Sugimoto N, Yachie A. Interleukin-33/ST2 signaling contributes to the severity of hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli. Clinical and experimental nephrology. 2019.04; 23 (4): 544-550. ( PubMed, DOI )

  81. Yamada Shimpei, Shimizu Masaki, Kuroda Mondo, Inoue Natsumi, Sugimoto Naotoshi, Yachie Akihiro. インターロイキン-33/ST2シグナル伝達は、腸管出血性大腸菌により誘発された溶血性尿毒症症候群の重症度に関係する(Interleukin-33/ST2 signaling contributes to the severity of hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli) Clinical and Experimental Nephrology. 2019.04; 23 (4): 544-550. ( ichushi )

  82. Yasuoka R, Iwata N, Abe N, Kohagura T, Nakaseko H, Shimizu M, Kawabe S. Risk factors for hypersensitivity reactions to tocilizumab introduction in systemic juvenile idiopathic arthritis. Modern rheumatology. 2019.03; 29 (2): 324-327. ( PubMed, DOI )

  83. Yasuoka Ryuhei, Iwata Naomi, Abe Naoki, Kohagura Toaki, Nakaseko Haruna, Shimizu Masaki, Kawabe Shinji. 全身型若年性特発性関節炎におけるトシリズマブ導入に対する過敏反応の危険因子(Risk factors for hypersensitivity reactions to tocilizumab introduction in systemic juvenile idiopathic arthritis) Modern Rheumatology. 2019.03; 29 (2): 324-327. ( ichushi )

  84. Sato A, Ikawa Y, Inoue N, Kuroda M, Shimizu M, Yachie A. Massive intestinal liquid retention in a case of severe heat stroke. Journal of paediatrics and child health. 2019.02; 55 (2): 248-249. ( PubMed, DOI )

  85. Okamoto Nami, Yokota Shumpei, Takei Syuji, Okura Yuka, Kubota Tomohiro, Shimizu Masaki, Nozawa Tomo, Iwata Naomi, Umebayashi Hiroaki, Kinjo Noriko, Kunishima Tomoko, Yasumura Junko, Mori Masaaki. Clinical practice guidance for juvenile idiopathic arthritis (JIA) 2018 MODERN RHEUMATOLOGY. 2019.01; 29 (1): 41-59. ( PubMed, DOI )

  86. Shimizu M, Nakase J, Yachie A. Infrapatellar Ganglion Cyst of the Knee Fat Pad in a Child with Juvenile Idiopathic Arthritis. The Journal of rheumatology. 2019.01; 46 (1): 112. ( PubMed, DOI )

  87. Okamoto Nami, Yokota Shumpei, Takei Syuji, Okura Yuka, Kubota Tomohiro, Shimizu Masaki, Nozawa Tomo, Iwata Naomi, Umebayashi Hiroaki, Kinjo Noriko, Kunishima Tomoko, Yasumura Junko, Mori Masaaki. 若年性特発性関節炎(JIA)診療ガイドライン2018(Clinical practice guidance for juvenile idiopathic arthritis(JIA) 2018) Modern Rheumatology. 2019.01; 29 (1): 41-59. ( ichushi )

  88. Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Serum Leucine-Rich <i>α</i>2-Glycoprotein as a Biomarker for Monitoring Disease Activity in Patients with Systemic Juvenile Idiopathic Arthritis. Journal of immunology research. 2019; 2019 3140204. ( PubMed, DOI )

  89. Shimizu M, Saikawa Y, Yachie A. Role of 18-fluoro-2-deoxyglucose positron emission tomography in detecting acute inflammatory lesions of non-bacterial osteitis in patients with a fever of unknown origin: A comparative study of 18-fluoro-2-deoxyglucose positron emission tomography, bone scan, and magnetic resonance imaging. Modern rheumatology. 2018.11; 28 (6): 1058-1062. ( PubMed, DOI )

  90. Shimizu Masaki, Saikawa Yutaka, Yachie Akihiro. 原因不明熱を呈する非細菌性骨炎患者の急性炎症性病変検出における18-フルオロ-2-デオキシグルコース陽電子放出断層撮影の役割 18-フルオロ-2-デオキシグルコース陽電子放射型断層撮影法、骨スキャン、磁気共鳴画像法の比較研究(Role of 18-fluoro-2-deoxyglucose positron emission tomography in detecting acute inflammatory lesions of non-bacterial osteitis in patients with a fever of unknown origin: A comparative study of 18-fluoro-2-deoxyglucose positron emission tomography, bone scan, and magnetic resonance imaging) Modern Rheumatology. 2018.11; 28 (6): 1058-1062. ( ichushi )

  91. Sakumura N, Shimizu M, Mizuta M, Inoue N, Nakagishi Y, Yachie A. Soluble CD163, a unique biomarker to evaluate the disease activity, exhibits macrophage activation in systemic juvenile idiopathic arthritis. Cytokine. 2018.10; 110 459-465. ( PubMed, DOI )

  92. Takakura M, Shimizu M, Yakoyama T, Mizuta M, Yachie A. Transient natural killer cell dysfunction associated with interleukin-18 overproduction in systemic juvenile idiopathic arthritis. Pediatrics international : official journal of the Japan Pediatric Society. 2018.10; 60 (10): 984-985. ( PubMed, DOI )

  93. Takakura Maiko, Shimizu Masaki, Yakoyama Tadafumi, Mizuta Mao, Yachie Akihiro. 全身性若年性特発性関節炎において一過性ナチュラルキラー細胞機能不全はインターロイキン-18過剰産生と関連する(Transient natural killer cell dysfunction associated with interleukin-18 overproduction in systemic juvenile idiopathic arthritis) Pediatrics International. 2018.10; 60 (10): 984-985. ( ichushi )

  94. Kubota T, Takei S, Shimizu M, Yasumura J, Nakagishi Y, Kizawa T, Yashiro M, Wakiguchi H, Yamasaki Y, Kawano Y. Early prediction for over two years efficacy of the first biologic agent for polyarticular juvenile idiopathic arthritis: A multi-institutional study in Japan. Modern rheumatology. 2018.09; 28 (5): 826-831. ( PubMed, DOI )

  95. Okamoto Nami, Shabana Kosuke, Nakagishi Yasuo, Nishimura Kenichi, Mizuta Mao, Okura Yuka, Shimizu Masaki, Wakiguchi Hiroyuki, Yasumura Junko, Mori Masaaki. Methotrexate Polyglutamates As an Evaluation Tool for Appropriate Dosage of Oral Methotrexate Administration in Pediatric Patients ARTHRITIS & RHEUMATOLOGY. 2018.09; 70

  96. Shimizu Masaki, Mizuta Mao, Yasumi Takahiro, Iwata Naomi, Okura Yuka, Kinjo Noriko, Umebayashi Hiroaki, Kubota Tomohiro, Nakagishi Yasuo, Nishimura Kenichi, Yashiro Masato, Yasumura Junko, Yamazaki Kazuko, Wakiguchi Hiroyuki, Okamoto Name, Mori Masaaki. Validation of Classification Criteria of Macrophage Activation Syndrome in Japanese Patients With Systemic Juvenile Idiopathic Arthritis ARTHRITIS CARE & RESEARCH. 2018.09; 70 (9): 1412-1415. ( PubMed, DOI )

  97. Kubota Tomohiro, Takei Syuji, Shimizu Masaki, Yasumura Junko, Nakagishi Yasuo, Kizawa Toshitaka, Yashiro Masato, Wakiguchi Hiroyuki, Yamasaki Yuichi, Kawano Yoshifumi. 多関節型若年性特発性関節炎に対して初回導入した生物学的製剤の2年以上の有効性に関する早期予測 日本における多施設共同研究(Early prediction for over two years efficacy of the first biologic agent for polyarticular juvenile idiopathic arthritis: A multi-institutional study in Japan) Modern Rheumatology. 2018.09; 28 (5): 826-831. ( ichushi )

  98. Shimizu M, Mizuta M, Usami M, Inoue N, Sakakibara Y, Yamada K, Konishi M, Ohta K, Yachie A. Clinical significance of serum soluble TNF receptor II level and soluble TNF receptor II/I ratio as indicators of coronary artery lesion development in Kawasaki disease. Cytokine. 2018.08; 108 168-172. ( PubMed, DOI )

  99. Takakura M, Shimizu M, Mizuta M, Inoue N, Tasaki Y, Ohta K, Furuichi K, Wada T, Yachie A. Successful treatment of rituximab- and steroid-resistant nephrotic syndrome with leukocytapheresis. Journal of clinical apheresis. 2018.06; 33 (3): 409-411. ( PubMed, DOI )

  100. Schulert GS, Minoia F, Bohnsack J, Cron RQ, Hashad S, KonÉ-Paut I, Kostik M, Lovell D, Maritsi D, Nigrovic PA, Pal P, Ravelli A, Shimizu M, Stanevicha V, Vastert S, Woerner A, de Benedetti F, Grom AA. Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis. Arthritis care & research. 2018.03; 70 (3): 409-419. ( PubMed, DOI )

  101. Kinjo N, Hamada K, Hirayama C, Shimizu M. Role of plasma exchange, leukocytapheresis, and plasma diafiltration in management of refractory macrophage activation syndrome. Journal of clinical apheresis. 2018.02; 33 (1): 117-120. ( PubMed, DOI )

  102. Tasaki Y, Shimizu M, Takarkura M, Ohta K, Yachie A. Urinary aquaporin-2 as a possible objective biomarker of nocturnal polyuria. Pediatrics international : official journal of the Japan Pediatric Society. 2018.02; 60 (2): 192-194. ( PubMed, DOI )

  103. Tasaki Yuko, Shimizu Masaki, Takarkura Maiko, Ohta Kazuhide, Yachie Akihiro. 夜間多尿の客観的バイオマーカーになり得る尿中aquaporin-2(Urinary aquaporin-2 as a possible objective biomarker of nocturnal polyuria) Pediatrics International. 2018.02; 60 (2): 192-194. ( ichushi )

  104. Niida Y, Ozaki M, Shimizu M, Ueno K, Tanaka T. Classification of Uniparental Isodisomy Patterns That Cause Autosomal Recessive Disorders: Proposed Mechanisms of Different Proportions and Parental Origin in Each Pattern. Cytogenetic and genome research. 2018; 154 (3): 137-146. ( PubMed, DOI )

  105. Mizuta M, Shimizu M, Nakagishi Y, Kasai K, Yachie A. Bicipital synovial cyst associated with systemic juvenile idiopathic arthritis: new insights obtained from unique pathological findings. International journal of rheumatic diseases. 2017.12; 20 (12): 2242-2244. ( PubMed, DOI )

  106. Shimizu Masaki, Inoue Natsumi, Kuroda Mondo, Irabu Hitoshi, Takakura Maiko, Kaneda Hisashi, Sugimoto Naotoshi, Ohta Kazuhide, Yachie Akihiro. 腸管出血性大腸菌誘発性の溶血性尿毒症症候群における脳障害発症の指標としての血清フェリチン(Serum ferritin as an indicator of the development of encephalopathy in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome) Clinical and Experimental Nephrology. 2017.12; 21 (6): 1083-1087. ( ichushi )

  107. Shimizu M, Inoue N, Kuroda M, Irabu H, Takakura M, Kaneda H, Sugimoto N, Ohta K, Yachie A. Serum ferritin as an indicator of the development of encephalopathy in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome. Clinical and experimental nephrology. 2017.12; 21 (6): 1083-1087. ( PubMed, DOI )

  108. Yasumura Junko, Yashiro Masato, Okamoto Nami, Shabana Kosuke, Umebayashi Hiroaki, Iwata Naomi, Kubota Tomohiro, Mizuta Mao, Nishimura Kenichi, Okura Yuka, Shimizu Masaki, Tomiita Minako, Takei Syuji, Mori Masaaki. Clinical Features and Characteristics of Juvenile Idiopathic Arthritis-Associated Uveitis in Japan: the First Report from the Pediatric Rheumatology Association of Japan (PRAJ) ARTHRITIS & RHEUMATOLOGY. 2017.10; 69

  109. Nagai T, Uemura O, Kaneda H, Ushijima K, Ohta K, Gotoh Y, Satomura K, Shimizu M, Fujieda M, Morooka M, Yamada T, Yamada M, Wada N, Hashimoto Y. The true distribution volume and bioavailability of mizoribine in children with chronic kidney disease. Clinical and experimental nephrology. 2017.10; 21 (5): 884-888. ( PubMed, DOI )

  110. Shimizu Masaki, Mizuta Mao, Yasumi Takahiro, Iwata Naomi, Okura Yuka, Kinjo Noriko, Umebayashi Hiroaki, Kubota Tomohiro, Nakagishi Yasuo, Nishimura Kenichi, Yashiro Masato, Yasumura Junko, Yamazaki Kazuko, Wakiguchi Hiroyuki, Okamoto Nami, Mori Masaaki. Validation of 2016 ACR/EULAR Classification Criteria of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis in Japanese Patients ARTHRITIS & RHEUMATOLOGY. 2017.10; 69

  111. Nagai Takuhito, Uemura Osamu, Kaneda Hisashi, Ushijima Katsumi, Ohta Kazuhide, Gotoh Yoshimitsu, Satomura Kenichi, Shimizu Masaki, Fujieda Mikiya, Morooka Masashi, Yamada Takuji, Yamada Masayoshi, Wada Naohiro, Hashimoto Yukiya. 慢性腎臓病を有する小児におけるミゾリビンの真の分布容積およびバイオアベイラビリティ(The true distribution volume and bioavailability of mizoribine in children with chronic kidney disease) Clinical and Experimental Nephrology. 2017.10; 21 (5): 884-888. ( ichushi )

  112. Shimizu M, Nakagishi Y, Inoue N, Mizuta M, Yachie A. Leucine-rich α2-glycoprotein as the acute-phase reactant to detect systemic juvenile idiopathic arthritis disease activity during anti-interleukin-6 blockade therapy: A case series. Modern rheumatology. 2017.09; 27 (5): 833-837. ( PubMed, DOI )

  113. Shimizu Masaki, Nakagishi Yasuo, Inoue Natsumi, Mizuta Mao, Yachie Akihiro. 抗インターロイキン-6遮断療法中の全身性若年性特発性関節炎疾患活動性を検出するための急性相反応物質としてのleucine-rich α2-glycoprotein 症例シリーズ(Leucine-rich α2-glycoprotein as the acute-phase reactant to detect systemic juvenile idiopathic arthritis disease activity during anti-interleukin-6 blockade therapy: A case series) Modern Rheumatology. 2017.09; 27 (5): 833-837. ( ichushi )

  114. Shimizu M, Shirahashi T, Mizuta M, Ikawa Y, Yachie A. Extracranial Carotid Aneurysm in Takayasu Arteritis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2017.08; 23 (5): 289. ( PubMed, DOI )

  115. Kaneda H, Shimizu M, Yachie A. Successful Treatment of Enterohemorrhagic Escherichia coli-Induced Acute Encephalopathy and Hemolytic-Uremic Syndrome With Polymyxin-B Direct Hemoperfusion. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 2017.08; 21 (4): 419-421. ( PubMed, DOI )

  116. Kaneda Hisashi, Shimizu Masaki, Yachie Akihiro. ポリミキシンB直接血液灌流による、腸管出血性大腸菌に誘発された急性脳症と溶血性尿毒症症候群に対する治療の成功(Successful Treatment of Enterohemorrhagic Escherichia coli-Induced Acute Encephalopathy and Hemolytic-Uremic Syndrome With Polymyxin-B Direct Hemoperfusion) Therapeutic Apheresis and Dialysis. 2017.08; 21 (4): 419-421. ( ichushi )

  117. Ishikawa S, Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Yachie A. Interleukin-33 as a marker of disease activity in rheumatoid factor positive polyarticular juvenile idiopathic arthritis. Modern rheumatology. 2017.07; 27 (4): 609-613. ( PubMed, DOI )

  118. Shimizu Masaki, Takakura Maiko, Inoue Natsumi, Ohta Kazuhide, Yachie Akihiro. 脾機能低下症患者における血小板増加症関連の腎糸球体症(Thrombocytosis-related glomerulopathy in a patient with hyposplenia) Pediatrics International. 2017.07; 59 (7): 842-843. ( ichushi )

  119. Shimizu M, Takakura M, Inoue N, Ohta K, Yachie A. Thrombocytosis-related glomerulopathy in a patient with hyposplenia. Pediatrics international : official journal of the Japan Pediatric Society. 2017.07; 59 (7): 842-843. ( PubMed, DOI )

  120. Ishikawa Sayaka, Shimizu Masaki, Inoue Natsumi, Mizuta Mao, Nakagishi Yasuo, Yachie Akihiro. リウマチ因子陽性の多関節型若年性特発性関節炎における疾患活動性マーカーとしてのインターロイキン-33(Interleukin-33 as a marker of disease activity in rheumatoid factor positive polyarticular juvenile idiopathic arthritis) Modern Rheumatology. 2017.07; 27 (4): 609-613. ( ichushi )

  121. Inoue Natsumi, Shimizu Masaki, Mizuta Mao, Ikawa Yasuhiro, Yachie Akihiro. 難治性の皮膚型結節性多発動脈炎 etanerceptによる治療の奏効(Refractory cutaneous polyarteritis nodosa: Successful treatment with etanercept) Pediatrics International. 2017.06; 59 (6): 751-752. ( ichushi )

  122. Inoue N, Shimizu M, Mizuta M, Ikawa Y, Yachie A. Refractory cutaneous polyarteritis nodosa: Successful treatment with etanercept. Pediatrics international : official journal of the Japan Pediatric Society. 2017.06; 59 (6): 751-752. ( PubMed, DOI )

  123. Shimizu M, Ikawa Y, Mizuta M, Takakura M, Inoue N, Nishimura R, Yachie A. FDG-PET in macrophage activation syndrome associated with systemic juvenile idiopathic arthritis. Pediatrics international : official journal of the Japan Pediatric Society. 2017.04; 59 (4): 509-511. ( PubMed, DOI )

  124. Shimizu Masaki, Ikawa Yasuhiro, Mizuta Mao, Takakura Maiko, Inoue Natsumi, Nishimura Ryosei, Yachie Akihiro. 若年性全身性特発性関節炎に関連したマクロファージ活性化症候群におけるFDG-PET(FDG-PET in macrophage activation syndrome associated with systemic juvenile idiopathic arthritis) Pediatrics International. 2017.04; 59 (4): 509-511. ( ichushi )

  125. Senda Y, Ohta K, Yokoyama T, Shimizu M, Furuichi K, Wada T, Yachie A. Microangiopathic antiphospholipid antibody syndrome due to anti-phosphatidylserine/prothrombin complex IgM antibody. Pediatrics international : official journal of the Japan Pediatric Society. 2017.03; 59 (3): 378-380. ( PubMed, DOI )

  126. Senda Yumi, Ohta Kazuhide, Yokoyama Tadafumi, Shimizu Masaki, Furuichi Kengo, Wada Takashi, Yachie Akihiro. 抗ホスファチジルセリン/プロトロンビン複合体IgM抗体に起因した微小血管障害性の抗リン脂質抗体症候群(Microangiopathic antiphospholipid antibody syndrome due to anti-phosphatidylserine/prothrombin complex IgM antibody) Pediatrics International. 2017.03; 59 (3): 378-380. ( ichushi )

  127. Shimizu M, Inoue N, Kuroda M, Mizuta M, Sugimoto N, Kaneda H, Ohta K, Yachie A. Angiopoietin-1 and -2 as markers for disease severity in hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli. Clinical and experimental nephrology. 2017.02; 21 (1): 76-82. ( PubMed, DOI )

  128. Shimizu Masaki, Inoue Natsumi, Kuroda Mondo, Mizuta Mao, Sugimoto Naotoshi, Kaneda Hisashi, Ohta Kazuhide, Yachie Akihiro. 腸管出血性大腸菌によって誘発された溶血性尿毒症症候群における疾患重症度マーカーとしてのアンジオポエチン-1および2(Angiopoietin-1 and -2 as markers for disease severity in hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli) Clinical and Experimental Nephrology. 2017.02; 21 (1): 76-82. ( ichushi )

  129. Ueno K, Shimizu M, Uchiyama A, Hatasaki K. Fulminant respiratory failure due to progressive metastatic pulmonary calcification with no predisposing factors after successful renal transplantation: A case report. Pediatric transplantation. 2016.12; 20 (8): 1152-1156. ( PubMed, DOI )

  130. Mizuta M, Shimizu M, Inoue N, Kasai K, Nakagishi Y, Takahara T, Hamahira K, Yachie A. Serum ferritin levels as a useful diagnostic marker for the distinction of systemic juvenile idiopathic arthritis and Kawasaki disease. Modern rheumatology. 2016.11; 26 (6): 929-932. ( PubMed, DOI )

  131. Kaneda H, Shimizu M, Ohta K, Ushijima K, Gotoh Y, Satomura K, Nagai T, Fujieda M, Morooka M, Yamada T, Yamada M, Wada N, Takaai M, Hashimoto Y, Uemura O. Population pharmacokinetics of mizoribine in pediatric patients with kidney disease. Clinical and experimental nephrology. 2016.10; 20 (5): 757-763. ( PubMed, DOI )

  132. Inoue N, Sato A, Ikawa Y, Shimizu M, Okajima M, Taniguchi T, Yachie A. Successful treatment of exertional heat stroke using continuous plasma diafiltration. Journal of clinical apheresis. 2016.10; 31 (5): 490-2. ( PubMed, DOI )

  133. Leu H, Sugimoto N, Shimizu M, Toma T, Wada T, Ohta K, Yachie A. Tumor necrosis factor-α modifies the effects of Shiga toxin on glial cells. International immunopharmacology. 2016.09; 38 139-43. ( PubMed, DOI )

  134. Inoue N, Shimizu M, Tsunoda S, Kawano M, Matsumura M, Yachie A. Cytokine profile in adult-onset Still's disease: Comparison with systemic juvenile idiopathic arthritis. Clinical immunology (Orlando, Fla.). 2016.08; 169 8-13. ( PubMed, DOI )

  135. Ueno K, Shimizu M, Kubo T, Igarashi N, Hatasaki K. An infant with nephrolithiasis and renal failure: Answers. Pediatric nephrology (Berlin, Germany). 2016.07; 31 (7): 1083-4. ( PubMed, DOI )

  136. Inoue N, Mizuta M, Shimizu M. Clinical Usefulness of 18F-fluorodeoxyglucose Positron Emission Tomography for Enthesitis-related Arthritis Diagnosis. The Journal of rheumatology. 2016.07; 43 (7): 1434-5. ( PubMed, DOI )

  137. Ueno K, Shimizu M, Kubo T, Igarashi N, Hatasaki K. An infant with nephrolithiasis and renal failure: Questions. Pediatric nephrology (Berlin, Germany). 2016.07; 31 (7): 1081-2. ( PubMed, DOI )

  138. Nakagishi Y, Shimizu M, Kasai K, Miyoshi M, Yachie A. Successful therapy of macrophage activation syndrome with dexamethasone palmitate. Modern rheumatology. 2016.07; 26 (4): 617-20. ( PubMed, DOI )

  139. Shimizu M, Inoue N, Mizuta M, Ikawa Y, Yachie A. Leopard skin appearance of cutaneous polyarteritis nodosa on 18Ffluorodeoxyglucose positron emission tomography. Rheumatology (Oxford, England). 2016.06; 55 (6): 1090. ( PubMed, DOI )

  140. Sawai T, Shimizu M, Sakai T, Yachie A. Tubulointerstitial Nephritis and Uveitis Syndrome Associated With Human Papillomavirus Vaccine. Journal of pediatric ophthalmology and strabismus. 2016.05; 53 (3): 190-1. ( PubMed, DOI )

  141. Tasaki Y, Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Wada T, Yachie A. Disruption of vascular endothelial homeostasis in systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: The dynamic roles of angiopoietin-1 and -2. Cytokine. 2016.04; 80 1-6. ( PubMed, DOI )

  142. Yokoyama K, Shimizu M, Yoshida A. Femoral Agminated Petechiae Associated with Acute Parvovirus B19 Infection. The Pediatric infectious disease journal. 2016.02; 35 (2): 228-9. ( PubMed, DOI )

  143. Tajiri H, Nishi J, Ushijima K, Shimizu T, Ishige T, Shimizu M, Tanaka H, Brooks S. A role for fosfomycin treatment in children for prevention of haemolytic-uraemic syndrome accompanying Shiga toxin-producing Escherichia coli infection. International journal of antimicrobial agents. 2015.11; 46 (5): 586-9. ( PubMed, DOI )

  144. Shimizu M, Nakagishi Y, Inoue N, Mizuta M, Ko G, Saikawa Y, Kubota T, Yamasaki Y, Takei S, Yachie A. Interleukin-18 for predicting the development of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Clinical immunology (Orlando, Fla.). 2015.10; 160 (2): 277-81. ( PubMed, DOI )

  145. Takakura M, Shimizu M, Inoue N, Tasaki Y, Ishikawa S, Ohta K, Yachie A. Iodine-induced non-autoimmune hypothyroidism in a patient with steroid-resistant nephrotic syndrome. Pediatrics international : official journal of the Japan Pediatric Society. 2015.10; 57 (5): 1055-6. ( PubMed, DOI )

  146. Sugimoto N, Leu H, Inoue N, Shimizu M, Toma T, Kuroda M, Saito T, Wada T, Yachie A. The critical role of lipopolysaccharide in the upregulation of aquaporin 4 in glial cells treated with Shiga toxin. Journal of biomedical science. 2015.09; 22 78. ( PubMed, DOI )

  147. Kuroda M, Shimizu M, Inoue N, Ikeno I, Nakagawa H, Yokoi A, Niida Y, Konishi M, Kaneda H, Igarashi N, Yamahana J, Taneichi H, Kanegane H, Ito M, Saito S, Furuichi K, Wada T, Nakagawa M, Yokoyama H, Yachie A. Serum tau protein as a marker of disease activity in enterohemorrhagic Escherichia coli O111-induced hemolytic uremic syndrome. Neurochemistry international. 2015.06; 85-86 24-30. ( PubMed, DOI )

  148. Shimizu M, Sakai S, Ohta K, Miyamoto M, Yachie A. Uterus didelphys with obstructed hemivagina and contralateral multicystic dysplastic kidney. CEN case reports. 2015.05; 4 (1): 61-64. ( PubMed, DOI )

  149. Ueno K, Shimizu M, Yokoyama T, Ishikawa S, Tasaki Y, Inoue N, Sugimoto N, Ohta K, Yachie A. Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. Clinical and experimental nephrology. 2015.04; 19 (2): 264-70. ( PubMed, DOI )

  150. Takahara T, Shimizu M, Nakagishi Y, Kinjo N, Yachie A. Serum IL-18 as a potential specific marker for differentiating systemic juvenile idiopathic arthritis from incomplete Kawasaki disease. Rheumatology international. 2015.01; 35 (1): 81-4. ( PubMed, DOI )

  151. Yokoyama T, Sugimoto N, Kato E, Ohta K, Ishikawa S, Ueno K, Shimizu M, Yachie A. Rotavirus gastroenteritis-associated urinary ammonium acid urate crystals. Pediatrics international : official journal of the Japan Pediatric Society. 2015; 57 (1): 158-60. ( PubMed, DOI )

  152. Shimizu M, Hamaguchi Y, Ishikawa S, Ueno K, Yachie A. Successful treatment with tocilizumab of a psoriasiform skin lesion induced by etanercept in a patient with juvenile idiopathic arthritis. Modern rheumatology. 2015; 25 (6): 972-3. ( PubMed, DOI )

  153. Shimizu M, Nakagishi Y, Yoshida A, Yachie A. Serum interleukin 18 as a diagnostic remission criterion in systemic juvenile idiopathic arthritis. The Journal of rheumatology. 2014.11; 41 (11): 2328-30. ( PubMed, DOI )

  154. Shimizu M, Ueno K, Ishikawa S, Tokuhisa Y, Inoue N, Yachie A. Treatment of refractory polyarticular juvenile idiopathic arthritis with tacrolimus. Rheumatology (Oxford, England). 2014.11; 53 (11): 2120-2. ( PubMed, DOI )

  155. Shimizu M, Niida Y, Koizumi S, Yachie A. An infant with recurrent convulsive seizures of 3 weeks duration: questions. Pediatric nephrology (Berlin, Germany). 2014.10; 29 (10): 1951, 1953-5. ( PubMed, DOI )

  156. Sugimoto N, Toma T, Shimizu M, Kuroda M, Wada T, Yachie A. Shiga toxin-2 enhances heat-shock-induced apoptotic cell death in cultured and primary glial cells. Cell biology and toxicology. 2014.10; 30 (5): 289-99. ( PubMed, DOI )

  157. Shimizu M, Nakayama Y, Taniguchi T. Successful treatment of enterohemorrhagic Escherichia coli O111-induced acute encephalopathy and hemolytic-uremic syndrome with plasma diafiltration. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 2014.10; 18 (5): 516-8. ( PubMed, DOI )

  158. Shimizu M, Sakai S, Tatekawa Y, Ishikawa S, Miyamoto M, Yachie A. An infant with PELVIS (perineal hemangioma, external genital malformations, lipomyelomeningocele, vesicorenal abnormalities, imperforate anus, and skin tag) syndrome misdiagnosed as diaper rash. The Journal of pediatrics. 2014.09; 165 (3): 634. ( PubMed, DOI )

  159. Shimizu M, Ueno K, Ishikawa S, Tokuhisa Y, Inoue N, Yachie A. Successful multitarget therapy using mizoribine and tacrolimus for refractory Takayasu arteritis. Rheumatology (Oxford, England). 2014.08; 53 (8): 1530-2. ( PubMed, DOI )

  160. Shimizu M, Ishikawa S, Yachi Y, Muraoka M, Tasaki Y, Iwasaki H, Kuroda M, Ohta K, Yachie A. Tolvaptan therapy for massive edema in a patient with nephrotic syndrome. Pediatric nephrology (Berlin, Germany). 2014.05; 29 (5): 915-7. ( PubMed, DOI )

  161. Shimizu M, Ueno K, Ishikawa S, Kasahara Y, Yachie A. Role of activated macrophage and inflammatory cytokines in the development of calcinosis in juvenile dermatomyositis. Rheumatology (Oxford, England). 2014.04; 53 (4): 766-7. ( PubMed, DOI )

  162. Shimizu M, Kuroda M, Inoue N, Konishi M, Igarashi N, Taneichi H, Kanegane H, Ito M, Saito S, Yachie A. Extensive serum biomarker analysis in patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome. Cytokine. 2014.03; 66 (1): 1-6. ( PubMed, DOI )

  163. Hoshino A, Shimizu M, Matsukura H, Sakaki-Nakatsubo H, Nomura K, Miyawaki T, Kanegane H. Allogeneic bone marrow transplantation appears to ameliorate IgA nephropathy in a patient with X-linked thrombocytopenia. Journal of clinical immunology. 2014.01; 34 (1): 53-7. ( PubMed, DOI )

  164. Shimizu M, Imai T. Vaginal cyst in a newborn. The Journal of pediatrics. 2013.12; 163 (6): 1790. ( PubMed, DOI )

  165. Shimizu M, Ueno K, Ishikawa S, Yokoyama T, Kasahara Y, Yachie A. Cutaneous calcinosis in juvenile dermatomyositis. The Journal of pediatrics. 2013.09; 163 (3): 921. ( PubMed, DOI )

  166. Shimizu M, Yokoyama T, Ishikawa S, Ueno K, Ohta K, Yachie A. A distinct lymphocyte distribution in relapse after rituximab for steroid-dependent nephrotic syndrome. CEN case reports. 2013.05; 2 (1): 1-5. ( PubMed, DOI )

  167. Ishikawa S, Shimizu M, Ueno K, Sugimoto N, Yachie A. Soluble ST2 as a marker of disease activity in systemic juvenile idiopathic arthritis. Cytokine. 2013.05; 62 (2): 272-7. ( PubMed, DOI )

  168. Shimizu M, Tokuhisa Y, Ishikawa S, Ueno K, Yokoyama T, Yachie A. Multiple osteonecrosis in a patient with juvenile systemic lupus erythematosus. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2013.04; 19 (3): 160. ( PubMed, DOI )

  169. Shimizu M, Ishikawa S, Ueno K, Yachie A. Moth-eaten appearance of tubulointerstitial nephritis and uveitis syndrome on (99m)technetium dimercaptosuccinic acid scintigraphy. The Journal of pediatrics. 2013.03; 162 (3): 647. ( PubMed, DOI )

  170. Shimizu Masaki, Kanegane Hirokazu, Wada Taizo, Motoyoshi Yaeko, Morio Tomohiro, Candotti Fabio, Yachie Akihiro. Aberrant glycosylation of IgA in Wiskott-Aldrich syndrome and X-linked thrombocytopenia JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013.02; 131 (2): 587-590. ( PubMed, DOI )

  171. Shimizu M, Yokoyama T, Tokuhisa Y, Ishikawa S, Sakakibara Y, Ueno K, Yachie A. Distinct cytokine profile in juvenile systemic lupus erythematosus-associated macrophage activation syndrome. Clinical immunology (Orlando, Fla.). 2013.02; 146 (2): 73-6. ( PubMed, DOI )

  172. Shimizu M, Nakagishi Y, Yachie A. Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles. Cytokine. 2013.02; 61 (2): 345-8. ( PubMed, DOI )

  173. Yokoyama T, Shimizu M, Ishikawa S, Ueno K, Hamaguchi Y, Takehara K, Yachie A. Accumulation of mature B cells in the inflamed muscle tissue of a patient with anti-155/140 antibody-positive juvenile dermatomyositis. Modern rheumatology. 2013.01; 23 (1): 167-71. ( PubMed, DOI )

  174. Shimizu M, Kuroda M, Sakashita N, Konishi M, Kaneda H, Igarashi N, Yamahana J, Taneichi H, Kanegane H, Ito M, Saito S, Ohta K, Taniguchi T, Furuichi K, Wada T, Nakagawa M, Yokoyama H, Yachie A. Cytokine profiles of patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome. Cytokine. 2012.12; 60 (3): 694-700. ( PubMed, DOI )

  175. Shimizu M, Hamaguchi Y, Matsushita T, Sakakibara Y, Yachie A. Sequentially appearing erythema nodosum, erythema multiforme and Henoch-Schönlein purpura in a patient with Mycoplasma pneumoniae infection: a case report. Journal of medical case reports. 2012.11; 6 398. ( PubMed, DOI )

  176. Shimizu M, Yachie A. Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages. Cytokine. 2012.10; 60 (1): 226-32. ( PubMed, DOI )

  177. Shimizu M, Ueno K, Yachie A. Relapse of systemic juvenile idiopathic arthritis after influenza vaccination in a patient receiving tocilizumab. Clinical and vaccine immunology : CVI. 2012.10; 19 (10): 1700-2. ( PubMed, DOI )

  178. Shimizu M, Yokoyama T, Sakashita N, Sato A, Ueno K, Akita C, Ohta K, Kitano E, Hatanaka M, Kitamura H, Saikawa Y, Yachie A. Thomsen-Friedenreich antigen exposure as a cause of Streptococcus pyogenes-associated hemolytic-uremic syndrome. Clinical nephrology. 2012.10; 78 (4): 328-31. ( PubMed, DOI )

  179. Shimizu M, Sakakibara Y, Kawano M, Yachie A. Transient impairment of NK cell function in an infant born to a mother with adult-onset Still's disease: perinatal effect of maternal IL-18. Clinical immunology (Orlando, Fla.). 2012.06; 143 (3): 273-4. ( PubMed, DOI )

  180. Shimizu M, Iwasaki H, Mase S, Yachie A. Successful treatment of primary sclerosing cholangitis with a steroid and a probiotic. Case reports in gastroenterology. 2012.05; 6 (2): 249-53. ( PubMed, DOI )

  181. Shimizu M, Nakagishi Y, Kasai K, Yamasaki Y, Miyoshi M, Takei S, Yachie A. Tocilizumab masks the clinical symptoms of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: the diagnostic significance of interleukin-18 and interleukin-6. Cytokine. 2012.05; 58 (2): 287-94. ( PubMed, DOI )

  182. Ohta K, Shimizu M, Yokoyama T, Nishio S, Ueno K, Seno A, Yachie A. Evaluation of T-Cell receptor diversity in pediatric patients with minimal change nephrotic syndrome. Clinical nephrology. 2012.04; 77 (4): 296-304. ( PubMed, DOI )

  183. Tokuhisa Y, Shimizu M, Yachie A. Honeycomb appearance of the liver in Wilson's disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2012.03; 10 (3): A25. ( PubMed, DOI )

  184. Shimizu M, Nishio S, Ueno K, Yokoyama T, Sakai S, Nagaoki S, Sugimoto N, Ohta K, Miyamoto M, Yachie A. Isolated congenital megacystis without intestinal obstruction: a mild variant of chronic intestinal pseudoobstruction syndrome? Journal of pediatric surgery. 2011.11; 46 (11): e29-32. ( PubMed, DOI )

  185. Shimizu M, Hashida Y, Ueno K, Yokoyama T, Nakayama Y, Saito T, Ohta K, Takehara K, Yachie A. Successful treatment with bosentan for pulmonary hypertension and reduced peripheral circulation in juvenile systemic sclerosis. Pediatric cardiology. 2011.10; 32 (7): 1040-2. ( PubMed, DOI )

  186. Ohta K, Yokoyama T, Shimizu M, Mizuno K, Sakazume S, Fujiki T, Saikawa Y, Yachie A. Diffusion-weighted MRI of exercise-induced acute renal failure (ALPE). Pediatric nephrology (Berlin, Germany). 2011.08; 26 (8): 1321-4. ( PubMed, DOI )

  187. Yokoyama T, Shimizu M, Ikeno I, Hashida Y, Fujita S, Shimura S, Hatasaki K, Shintani N, Yachie A. [Case of systemic-onset juvenile idiopathic arthritis complicated with sepsis --usefulness of cytokine profile for the differentiation between macrophage activation syndrome and sepsis]. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. 2011; 34 (2): 105-11. ( PubMed, DOI )

  188. Yokoyama T, Shimizu M, Ohta K, Yuno T, Okajima M, Wada T, Toma T, Koizumi S, Yachie A. Urinary heme oxygenase-1 as a sensitive indicator of tubulointerstitial inflammatory damage in various renal diseases. American journal of nephrology. 2011; 33 (5): 414-20. ( PubMed, DOI )

  189. Shimizu M, Tone Y, Toga A, Yokoyama T, Wada T, Toma T, Yachie A. Colchicine-responsive chronic recurrent multifocal osteomyelitis with MEFV mutations: a variant of familial Mediterranean fever? Rheumatology (Oxford, England). 2010.11; 49 (11): 2221-3. ( PubMed, DOI )

  190. Wada T, Mase S, Shibata F, Shimizu M, Toma T, Yachie A. Differential resistance to antiviral drugs in an immunocompromised patient with cytomegalovirus encephalitis. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 2010.11; 49 (3): 223-4. ( PubMed, DOI )

  191. Shimizu M, Yokoyama T, Yamada K, Kaneda H, Wada H, Wada T, Toma T, Ohta K, Kasahara Y, Yachie A. Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis. Rheumatology (Oxford, England). 2010.09; 49 (9): 1645-53. ( PubMed, DOI )

  192. Shimizu M, Kitagawa K, Nishio S, Yokoyama T, Furuichi K, Ohta K, Wada T, Yachie A. Successful treatment of recurrent focal segmental glomerulosclerosis after renal transplantation by lymphocytapheresis and rituximab. Transplant international : official journal of the European Society for Organ Transplantation. 2010.09; 23 (9): e53-5. ( PubMed, DOI )

  193. Nikolov NP, Shimizu M, Cleland S, Bailey D, Aoki J, Strom T, Schwartzberg PL, Candotti F, Siegel RM. Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein. Blood. 2010.08; 116 (5): 740-7. ( PubMed, DOI )

  194. Shimizu M, Yokoyama T, Wada T, Yachie A. Bicipital synovial cyst in systemic-onset juvenile idiopathic arthritis. The Journal of pediatrics. 2010.07; 157 (1): 168. ( PubMed, DOI )

  195. Masaki Shimizu, Tamejiro Hiyama. Organic fluorophores exhibiting highly efficient photoluminescence in the solid state. Chem Asian J. 2010.07; 5 (7): 1516-1531. ( PubMed, DOI )

  196. Wada T, Yokoyama T, Nakagawa H, Asai E, Toga A, Sakakibara Y, Shibata F, Tone Y, Shimizu M, Toma T, Yachie A. Flow cytometric analysis of skin blister fluid induced by mosquito bites in a patient with chronic active Epstein-Barr virus infection. International journal of hematology. 2009.12; 90 (5): 611-615. ( PubMed, DOI )

  197. Shimizu M, Araki R, Niida Y, Nakada M, Yachie A, Kamide T, Yokoyama T, Iwasa T, Kubo T. Mollaret meningitis associated with occipital dermal sinus. The Journal of pediatrics. 2009.11; 155 (5): 757.e1. ( PubMed, DOI )

  198. Shimizu M, Yamazaki M, Horisawa T, Seno A, Ohta K, Furuichi K, Yachie A. Catastrophic anti-phospholipid syndrome associated with Escherichia coli O157 infection. Rheumatology (Oxford, England). 2009.09; 48 (9): 1168-9. ( PubMed, DOI )

  199. Wada T, Yasui M, Toma T, Nakayama Y, Nishida M, Shimizu M, Okajima M, Kasahara Y, Koizumi S, Inoue M, Kawa K, Yachie A. Detection of T lymphocytes with a second-site mutation in skin lesions of atypical X-linked severe combined immunodeficiency mimicking Omenn syndrome. Blood. 2008.09; 112 (5): 1872-5. ( PubMed, DOI )

  200. Ohta K, Shimizu M, Nakai A, Toma T, Kasahara Y, Arii C, Yachie A, Kawamura T, Aikawa A, Hasegawa A, Sato K, Yokoyama H, Ishikawa I, Koizumi S. Rituximab therapy for Epstein-Barr virus-related chronic hepatitis following living donor kidney transplantation. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2006.12; 48 (6): 986-9. ( PubMed, DOI )

  201. Shimizu M, Ohta K, Wada H, Sumita R, Yachie A, Koizumi S. Cytomegalovirus-associated protracted diarrhoea in an immunocompetent boy. Journal of paediatrics and child health. 2006.05; 42 (5): 259-62. ( PubMed, DOI )

  202. Shimizu M, Ohta K, Yang Y, Nakai A, Toma T, Saikawa Y, Kasahara Y, Yachie A, Yokoyama H, Seki H, Koizumi S. Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells. Pediatric research. 2005.10; 58 (4): 666-71. ( PubMed, DOI )

  203. Shimizu M, Katayama K, Kato E, Miyayama S, Sugata T, Ohta K. Evolution of acute focal bacterial nephritis into a renal abscess. Pediatric nephrology (Berlin, Germany). 2005.01; 20 (1): 93-5. ( PubMed, DOI )

  204. Yang Y, Ohta K, Shimizu M, Morimoto K, Goto C, Nakai A, Toma T, Kasahara Y, Yachie A, Seki H, Koizumi S. Selective protection of renal tubular epithelial cells by heme oxygenase (HO)-1 during stress-induced injury. Kidney international. 2003.10; 64 (4): 1302-9. ( PubMed, DOI )

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Books etc 【 display / non-display

  1. Masaki Shimizu. Cytokine Storm Syndrome. Springer, 2019.09 Clinical Features of Cytokine Storm Syndrome (ISBN : 978-3-030-22094-5)

Conference Activities & Talks 【 display / non-display

  1. Kaneko S, Shimbo A,Irabu H, Shimizu M, Mori M, Morio T.. Clinical significance of serum cytokine profiling for the differentiation of underlying diseases in cytokine storm syndrome. The 2nd International Symposium of Clinical Immunology 2023.05.19 Kanagawa

  2. Masaki Shimizu. Macrophage Activation Syndrome: Analysis of various Cytokines. 22nd Asia-Pacific League of Associations for Rheumatology Congress 2020.10.24 Kyoto

Others 【 display / non-display

  • 2022.02

    Macrophage activation syndrome -Pathogenesis and treatment strategy(SHIMIZU Masaki)