Personnel Information

写真a

UESAKA Naofumi


Job title

Professor

Homepage URL

https://uesaka0808.wixsite.com/website

Research Areas, Keywords

Neuron, Glia, Cerebellum, Cortex, Molecular mechanisms, Activity-dependent, Neural circuit formation, Cell-cell interaction

Graduate School 【 display / non-display

  • Osaka University, Graduate School, Division of Engineering Science, Doctor's Course, 2006.03, Completed

Campus Career 【 display / non-display

  • 2020.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Maxillofacial and Neck Reconstruction, Cognitive Neurobiology, Professor

External Career 【 display / non-display

  • 2010.09
    -
    2017.03
    The University of Tokyo, Graduate School of Medicine, Assistant Professor
  • 2015.11
    -
    2017.03
    RWTH Aachen Germany, Research fellow
  • 2018.04
    -
    2020.03
    The University of Tokyo, Graduate School of Medicine, Junior Associate Professor

Research Areas 【 display / non-display

  • Cell biology

  • General physiology

  • Molecular biology

  • Neurophysiology / General neuroscience

 

Published Papers & Misc 【 display / non-display

  • Nagahama K, Fujino S, Watanabe T, Uesaka N, Kano M. Combining electrophysiology and optogenetics for functional screening of pyramidal neurons in the mouse prefrontal cortex. STAR protocols. 2021.06; 2 (2): 100469. ( PubMed, DOI )

  • Fleck D, Kenzler L, Mundt N, Strauch M, Uesaka N, Moosmann R, Bruentgens F, Missel A, Mayerhofer A, Merhof D, Spehr J, Spehr M. ATP activation of peritubular cells drives testicular sperm transport. eLife. 2021.01; 10 ( PubMed, DOI )

  • Yamashiro K, Hori K, Lai ESK, Aoki R, Shimaoka K, Arimura N, Egusa SF, Sakamoto A, Abe M, Sakimura K, Watanabe T, Uesaka N, Kano M, Hoshino M. AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication. iScience. 2020.12; 23 (12): 101820. ( PubMed, DOI )

  • Sacai H, Sakoori K, Konno K, Nagahama K, Suzuki H, Watanabe T, Watanabe M, Uesaka N, Kano M. Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex. Nature communications. 2020.10; 11 (1): 5140. ( PubMed, DOI )

  • Nagumo Yasuyuki, Ueta Yoshifumi, Nakayama Hisako, Osaki Hironobu, Takeuchi Yuichi, Uesaka Naofumi, Kano Masanobu, Miyata Mariko. Tonic GABAergic Inhibition Is Essential for Nerve Injury-Induced Afferent Remodeling in the Somatosensory Thalamus and Ectopic Sensations CELL REPORTS. 2020.06; 31 (12): 107797. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • 上阪直史. Astrocytes regulate synapse elimination in the developing cerebellum.. 第64回日本神経化学会大会 2021.10.01

  • 上阪 直史,赤松 翼,鈴木 穂香,狩野 方伸. アストロサイトは2型イノシトール3リン酸受容体を介して発達期小脳のシナプス刈り込みを制御する. 第98回 日本生理学会大会 2021.03.29 日本(Webシンポジウム)

  • 上阪直史. Astrocytes regulate synapse elimination in the developing cerebellum. 遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム」 2020.12.11 日本(Webシンポジウム)

  • 上阪直史. 運動機能を司る小脳の発達:咀嚼嚥下の機能発達の理解を目指して. 第62回 歯科基礎医学会学術大会 2020.09.22 日本(Webシンポジウム)

  • 渡邉 貴樹1,2, 佐郡 和人1, 鈴木 穂香1, 赤松 翼1, 松山 恭子1, 井上 秀太郎1, 阿部 学3, 﨑村 建司3, 上阪 直史1,2, 狩野 方伸1,2. Protocadherin 10は一部のアルドラーゼC陽性の小脳プルキンエ細胞において発達期の登上線維シナプスの刈り込みを遅延させる. 2020.07.29

 

Performance of duties 【 display / non-display

  • ,2021.08 - Now

  • ,2021.04 - Now

  • ,2021.04 - Now

  • ,2021.04 - Now

  • ,2021.04 - Now

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