Nagahama K, Fujino S, Watanabe T, Uesaka N, Kano M. Combining electrophysiology and optogenetics for functional screening of pyramidal neurons in the mouse prefrontal cortex. STAR protocols. 2021.06; 2 (2): 100469. ( PubMed, DOI )

Fleck D, Kenzler L, Mundt N, Strauch M, Uesaka N, Moosmann R, Bruentgens F, Missel A, Mayerhofer A, Merhof D, Spehr J, Spehr M. ATP activation of peritubular cells drives testicular sperm transport. eLife. 2021.01; 10 ( PubMed, DOI )

Yamashiro K, Hori K, Lai ESK, Aoki R, Shimaoka K, Arimura N, Egusa SF, Sakamoto A, Abe M, Sakimura K, Watanabe T, Uesaka N, Kano M, Hoshino M. AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication. iScience. 2020.12; 23 (12): 101820. ( PubMed, DOI )

Sacai H, Sakoori K, Konno K, Nagahama K, Suzuki H, Watanabe T, Watanabe M, Uesaka N, Kano M. Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex. Nature communications. 2020.10; 11 (1): 5140. ( PubMed, DOI )

Nagumo Yasuyuki, Ueta Yoshifumi, Nakayama Hisako, Osaki Hironobu, Takeuchi Yuichi, Uesaka Naofumi, Kano Masanobu, Miyata Mariko. Tonic GABAergic Inhibition Is Essential for Nerve Injury-Induced Afferent Remodeling in the Somatosensory Thalamus and Ectopic Sensations CELL REPORTS. 2020.06; 31 (12): 107797. ( PubMed, DOI )

Rai Y, Watanabe T, Matsuyama K, Sakimura K, Uesaka N, Kano M. Phospholipase C β3 is Required for Climbing Fiber Synapse Elimination in Aldolase C-positive Compartments of the Developing Mouse Cerebellum. Neuroscience. 2020.04; ( PubMed, DOI )

Watanabe Takaki, Suzuki Honoka, Sakoori Kazuto, Inoue Shutaro, Akamatsu Tsubasa, Abe Manabu, Sakimura Kenji, Uesaka Naofumi, Kano Masanobu. Protocadherin 10 delays developmental climbing fiber synapse elimination in a subset of aldolase C-positive Purkinje cells in the cerebellum(和訳中) The Journal of Physiological Sciences. 2020.03; 70 (Suppl.1): S97. ( ichushi )

Saito R, Koebis M, Nagai T, Shimizu K, Liao J, Wulaer B, Sugaya Y, Nagahama K, Uesaka N, Kushima I, Mori D, Maruyama K, Nakao K, Kurihara H, Yamada K, Kano M, Fukada Y, Ozaki N, Aiba A. Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus. Translational psychiatry. 2020.02; 10 (1): 35. ( PubMed, DOI )

Kushibe Kyoko, Mercier Celine, Watanabe Takaki, Miyazaki Taisuke, Yamasaki Miwako, Watanabe Masahiko, Uesaka Naofumi, Kano Masanobu. Fndc3bは小脳のSTAT3を阻害することにより登上線維のシナプス刈り込みを部分的に促進する(Fndc3b promotes climbing fiber synapse elimination partly by inhibiting STAT3 in the cerebellum) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S127. ( ichushi )

Nagahama Kenichiro, Sakoori Kazuto, Watanabe Takaki, Uesaka Naofumi, Kano Masanobu. 精神障害関連エピジェネティック因子の欠如による前頭前野でのシナプス入力の減少(Reduced synaptic inputs in prefrontal cortex by lack of a mental disorder-related epigenetic factor) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S143. ( ichushi )

Uesaka Naofumi, Kao Tzu-Huei, Kano Masanobu. 健康および疾患におけるシナプスのリモデリングとその先　小脳発生における活動依存性シナプス刈り込み(Synaptic remodeling and beyond in health and disease　Activity-dependent synapse elimination in the developing cerebellum) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S35. ( ichushi )

Watanabe Takaki, Inoue Shutaro, Akamatsu Tsubasa, Suzuki Honoka, Abe Manabu, Sakimura Kenji, Uesaka Naofumi, Kano Masanobu. Protocadherin 10を欠く小脳プルキンエ細胞における登上線維のシナプス刈り込みの促進(Accelerated climbing fiber synapse elimination in cerebellar Purkinje cells lacking protocadherin 10) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S221. ( ichushi )

Kano M, Watanabe T, Uesaka N, Watanabe M. Multiple Phases of Climbing Fiber Synapse Elimination in the Developing Cerebellum. Cerebellum (London, England). 2018.12; 17 (6): 722-734. ( PubMed, DOI )

Nagahama Kenichiro, Sakoori Kazuto, Watanabe Takaki, Uesaka Naofumi, Kano Masanobu. 生後発達期のマウス内側前頭前野のニューロンにおいて統合失調症関連分子Setd1aをノックダウンした場合のシナプス伝達の減弱(Reduced synaptic transmission in neurons of mouse medial prefrontal cortex by knockdown of a schizophrenia-related molecule, Setd1a, during postnatal development) The Journal of Physiological Sciences. 2018.03; 68 (Suppl.1): S131. ( ichushi )

Uesaka N, Kano M. Presynaptic Mechanisms Mediating Retrograde Semaphorin Signals for Climbing Fiber Synapse Elimination During Postnatal Cerebellar Development. Cerebellum (London, England). 2018.02; 17 (1): 17-22. ( PubMed, DOI )

Uesaka N, Abe M, Konno K, Yamazaki M, Sakoori K, Watanabe T, Kao TH, Mikuni T, Watanabe M, Sakimura K, Kano M. Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum. Neuron. 2018.02; 97 (4): 796-805.e5. ( PubMed, DOI )

Choo M, Miyazaki T, Yamazaki M, Kawamura M, Nakazawa T, Zhang J, Tanimura A, Uesaka N, Watanabe M, Sakimura K, Kano M. Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum. Nature communications. 2017.08; 8 (1): 195. ( PubMed, DOI )

Leto Ketty, Arancillo Marife, Becker Esther B. E., Buffo Annalisa, Chiang Chin, Ding Baojin, Dobyns William B., Dusart Isabelle, Haldipur Parthiv, Hatten Mary E., Hoshino Mikio, Joyner Alexandra L., Kano Masanobu, Kilpatrick Daniel L., Koibuchi Noriyuki, Marino Silvia, Martinez Salvador, Millen Kathleen J., Millner Thomas O., Miyata Takaki, Parmigiani Elena, Schilling Karl, Sekerkova Gabriella, Sillitoe Roy V., Sotelo Constantino, Uesaka Naofumi, Wefers Annika, Wingate Richard J. T., Hawkes Richard. Consensus Paper: Cerebellar Development CEREBELLUM. 2016.12; 15 (6): 789-828. ( DOI )

Narushima Madoka, Uchigashima Motokazu, Yagasaki Yuki, Harada Takeshi, Nagumo Yasuyuki, Uesaka Naofumi, Hashimoto Kouichi, Aiba Atsu, Watanabe Masahiko, Miyata Mariko, Kano Masanobu. The Metabotropic Glutamate Receptor Subtype 1 Mediates Experience-Dependent Maintenance of Mature Synaptic Connectivity in the Visual Thalamus NEURON. 2016.09; 91 (5): 1097-1109. ( DOI )

Uesaka Naofumi, Uchigashima Motokazu, Mikuni Takayasu, Hirai Hirokazu, Watanabe Masahiko, Kano Masanobu. Retrograde Signaling for Climbing Fiber Synapse Elimination CEREBELLUM. 2015.02; 14 (1): 4-7. ( DOI )

Uesaka Naofumi, Uchigashima Motokazu, Mikuni Takayasu, Nakazawa Takanobu, Nakao Harumi, Hirai Hirokazu, Aiba Atsu, Watanabe Masahiko, Kano Masanobu. Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain SCIENCE. 2014.05; 344 (6187): 1020-1023. ( DOI )

Mikuni Takayasu, Uesaka Naofumi, Okuno Hiroyuki, Hirai Hirokazu, Deisseroth Karl, Bito Haruhiko, Kano Masanobu. Arc/Arg3.1 Is a Postsynaptic Mediator of Activity-Dependent Synapse Elimination in the Developing Cerebellum NEURON. 2013.06; 78 (6): 1024-1035. ( DOI )

Uesaka Naofumi, Mikuni Takayasu, Hirai Hirokazu, Kano Masanobu. Cell-type specific gene transfer in olivo-cerebellar coculture preparation for the study of developmental synapse elimination JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013; 63 (1): S40.

Uesaka Naofumi, Mikuni Takayasu, Hashimoto Kouichi, Hirai Hirokazu, Sakimura Kenji, Kano Masanobu. Organotypic Coculture Preparation for the Study of Developmental Synapse Elimination in Mammalian Brain JOURNAL OF NEUROSCIENCE. 2012.08; 32 (34): 11657-11670. ( DOI )

Tanimura Asami, Uchigashima Motokazu, Yamazaki Maya, Uesaka Naofumi, Mikuni Takayasu, Abe Manabu, Hashimoto Kouichi, Watanabe Masahiko, Sakimura Kenji, Kano Masanobu. Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012.07; 109 (30): 12195-12200. ( DOI )

Mikuni Takayasu, Uesaka Naofumi, Kano Masanobu. Roles of Purkinje cell activity in climbing fiber synapse elimination in an organotypic coculture preparation of the cerebellum and medulla oblongata NEUROSCIENCE RESEARCH. 2011; 71 (S): E93. ( DOI )

Tanimura Asami, Yamazaki Maya, Uchigashima Motokazu, Uesaka Naofumi, Mikuni Takayasu, Hashimoto Kouichi, Watanabe Masahiko, Sakimura Kenji, Kano Masanobu. Synapse "non-specific" degradation of the endocannabinoid 2-arachidonoylglycerol mediating depolarization-induced retrograde synaptic suppression in cerebellar Purkinje cells NEUROSCIENCE RESEARCH. 2011; 71 (S): E56. ( DOI )

Sugo Noriyuki, Oshiro Hiroaki, Takemura Mitsuhiro, Kobayashi Toshiaki, Kohno Yusuke, Uesaka Naofumi, Song Wen-Jie, Yamamoto Nobuhiko. Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons EUROPEAN JOURNAL OF NEUROSCIENCE. 2010.05; 31 (9): 1521-1532. ( DOI )

Yamada Akito, Uesaka Naofumi, Hayano Yasufumi, Tabata Toshihide, Kano Masanobu, Yamamoto Nobuhiko. Role of pre- and postsynaptic activity in thalamocortical axon branching PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010.04; 107 (16): 7562-7567. ( DOI )

Mikuni Takayasu, Uesaka Naofumi, Kano Masanobu. Applications of gene transfer techniques to CNS organotypic cultures JOURNAL OF PHYSIOLOGICAL SCIENCES. 2010; 60 (1): S135.

Uesaka Naofumi, Mikuni Takayasu, Kano Masanobu. An in vitro coculture preparation suitable for investigating the mechanisms of synapse development in rodent cerebellum NEUROSCIENCE RESEARCH. 2010; 68 (1): E61. ( DOI )

Mikuni Takayasu, Uesaka Naofumi, Kano Masanobu. Effective modification of neural activity in CNS organotypic cultures NEUROSCIENCE RESEARCH. 2010; 68 (1): E135. ( DOI )

Uesaka Naofumi, Mikuni Takayasu, Kano Masanobu. Gene transfer techniques for CNS organotypic cultures NEUROSCIENCE RESEARCH. 2009; 65 (1): S132-S133. ( DOI )

Ohnami Soichiro, Endo Mitsuharu, Hirai Satoshi, Uesaka Naofumi, Hatanaka Yumiko, Yamashita Toshihide, Yamamoto Nobuhiko. Role of RhoA in activity-dependent cortical axon branching JOURNAL OF NEUROSCIENCE. 2008.09; 28 (37): 9117-9121. ( DOI )

Uesaka Naofumi, Nishiwaki Maki, Yamamoto Nobuhiko. Single cell electroporation method for axon tracing in cultured slices DEVELOPMENT GROWTH & DIFFERENTIATION. 2008.08; 50 (6): 475-477. ( DOI )

Ohnami Soichiro, Endo Mitsuharu, Hirai Satoshi, Uesaka Naofumi, Hatanaka Yumiko, Yamashita Toshihide, Yamamoto Nobuhiko. RhoA is involved in activity-dependent cortical axon branching NEUROSCIENCE RESEARCH. 2008; 61 S233.

Uesaka Naofumi, Kano Masanobu. Formation of functional synapses in organotypic cocultures of the medulla and cerebellum NEUROSCIENCE RESEARCH. 2008; 61 S88.

Uesaka Naofumi, Hayano Yasufumi, Yamada Akito, Yamamoto Nobuhiko. Interplay between laminar specificity and activity-dependent mechanisms of thalamocortical axon branching JOURNAL OF NEUROSCIENCE. 2007.05; 27 (19): 5215-5223. ( DOI )

Yamada Akito, Uesaka Naofumi, Hayano Yasufumi, Tabata Toshihide, Kano Masanobu, Yamamoto Nobuhiko. The role of neural activities of thalamic and cortical neurons in thalamocortical axon branching NEUROSCIENCE RESEARCH. 2007; 58 (1): S89. ( DOI )

Uesaka N, Ruthazer ES, Yamamoto N. The role of neural activity in cortical axon branching NEUROSCIENTIST. 2006.04; 12 (2): 102-106. ( DOI )

Sugo Noriyuki, Takemura Mitsuhiro, Kobayashi Toshiald, Uesaka Naofumi, Yamamoto Nobuhiko. Activity-dependent nucleocytoplasmic translocation of HDAC9 in cortical neurons NEUROSCIENCE RESEARCH. 2006; 55 (1): S53.

Uesaka Naofumi, Hayano Yasufumi, Yamada Akito, Yamamoto Nobuhiko. The role of neuronal activity in lamina-specific thalamocortical axon branching NEUROSCIENCE RESEARCH. 2006; 55 (1): S63.

Uesaka N, Hirai S, Maruyama T, Ruthazer ES, Yamamoto N. Activity dependence of cortical axon branch formation: A morphological and electrophysiological study using organotypic slice cultures JOURNAL OF NEUROSCIENCE. 2005.01; 25 (1): 1-9. ( DOI )

Naofumi Uesaka, Daisuke Kawauchi. Neuronal and Synaptic Influences on Brain Tumors. シナプス研究会2023 2023.10.19

上阪 直史. 発達期小脳オリゴデンドロサイトはシナプス刈り込みと脳機能を制御する. 第46回日本神経科学大会 2023.08.04

Naofumi Uesaka, Daisuke Kawauchi. Conditional expression and activation of DREADDs reveals novel impact of neuron-tumor communications on brain tumor progression. 1st Heidelberg Conference on Cancer Neuroscience 2023.07.18 Germany

Uesaka Naofumi, Masumura Ryo, Sekiguchi Mariko. Development of cell-type specific AAV vectors in the mouse brain(タイトル和訳中). The Journal of Physiological Sciences 2023.05.01

Masumura Ryo, Uesaka Naofumi. Developmental oligodendrocytes contribute to cerebellar maturation(タイトル和訳中). The Journal of Physiological Sciences 2023.05.01

Tanigawa Moe, Kato Chiho, Ono Takashi, Uesaka Naofumi. Effects of unilateral nasal obstruction during the growth period on cerebellar neural circuit and function(タイトル和訳中). The Journal of Physiological Sciences 2023.05.01

谷川 萌1、加藤 千帆1、小野 卓史1、上阪 直史. 成長期の鼻呼吸障害が小脳の神経回路と機能に及ぼす影響. 日本生理学会　第１００回記念大会 2023.03.15

上阪　直史、増村　嶺、関口　真理子. 脳における細胞タイプ特異的なAAVベクターの開発. 日本生理学会第100回記念大会 2023.03.15

増村　嶺、上阪　直史. 発達期オリゴデンドロサイトが小脳の成熟に貢献する. 日本生理学会第100回記念大会 2023.03.15

Uesaka Naofumi, Kano Masanobu. Recent advances in synapse remodeling　Astrocyte-Neuron signaling in developmental synapse remodeling(タイトル和訳中). The Journal of Physiological Sciences 2022.12.01

Itami Chiaki, Uesaka Naofumi, Huang Jui-Yen, Lu Hui-Chen, Sakimura Kenji, Kano Masanobu, Kimura Fumitaka. Endocannabinoid-dependent formation of columnar axonal projection of layer 4 neurons in the mouse cerebral cortex(タイトル和訳中). The Journal of Physiological Sciences 2022.12.01

Uesaka Naofumi, Kano Masanobu. シナプスリモデリング機構の最近の進歩　発達期のシナプスリモデリングにおけるアストロサイトとニューロンのシグナル伝達(Recent advances in synapse remodeling　Astrocyte-Neuron signaling in developmental synapse remodeling). The Journal of Physiological Sciences 2022.12.01

Itami Chiaki, Uesaka Naofumi, Huang Jui-Yen, Lu Hui-Chen, Sakimura Kenji, Kano Masanobu, Kimura Fumitaka. マウス大脳皮質における内在性カンナビノイド依存的な第4層ニューロンの柱状軸索投射の形成(Endocannabinoid-dependent formation of columnar axonal projection of layer 4 neurons in the mouse cerebral cortex). The Journal of Physiological Sciences 2022.12.01

増村嶺、上阪直史. Cerebellar oligodendrocytes during development shape cerebellar circuit and behaviors. 第４５回日本分子生物学会 2022.11.30

上阪　直史. From Astrocyte to Neuron signaling in developmental synapse remodeling. 第3回先端脳科学国際シンポジウム 2022.03.30 山梨県甲府市

上阪　直史、狩野　方伸. Astrocyte-Neuron signaling in developmental synapse remodeling. 第99回日本生理学会大会 2022.03.17 東北大学、宮城

上阪直史. Astrocytes regulate synapse elimination in the developing cerebellum.. 第64回日本神経化学会大会 2021.10.01

上阪 直史,赤松 翼,鈴木 穂香,狩野 方伸. アストロサイトは2型イノシトール3リン酸受容体を介して発達期小脳のシナプス刈り込みを制御する. 第９８回　日本生理学会大会 2021.03.29 日本（Webシンポジウム）

上阪直史. Astrocytes regulate synapse elimination in the developing cerebellum. 遺伝研研究会「哺乳類脳の機能的神経回路の構築メカニズム」 2020.12.11 日本（Webシンポジウム）

上阪直史. 運動機能を司る小脳の発達：咀嚼嚥下の機能発達の理解を目指して. 第62回 歯科基礎医学会学術大会 2020.09.22 日本（Webシンポジウム）

渡邉 貴樹1,2, 佐郡 和人1, 鈴木 穂香1, 赤松 翼1, 松山 恭子1, 井上 秀太郎1, 阿部 学3, 﨑村 建司3, 上阪 直史1,2, 狩野 方伸1,2. Protocadherin 10は一部のアルドラーゼＣ陽性の小脳プルキンエ細胞において発達期の登上線維シナプスの刈り込みを遅延させる. 2020.07.29