Personnel Information

写真a

KOFUJI Satoshi


Job title

Junior Associate Professor

Homepage URL

http://www.tmd.ac.jp/mri/dbio/indexE.html

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Pharmaceutical Science, 2003.03, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Pharmaceutical Sciences, Master's Course, 2005.03, Completed

  • The University of Tokyo, Graduate School, Division of Pharmaceutical Sciences, Doctor's Course, 2008.03, Accomplished credits for doctoral program

Campus Career 【 display / non-display

  • 2019.12
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Pathophysiology, Developmental and Regenerative Biology, Junior Associate Professor

External Career 【 display / non-display

  • 2008.04
    -
    2008.07
    , Project Researcher
  • 2008.08
    -
    2009.03
    , Project Assistant Professor
  • 2009.04
    -
    2012.03
    , Project Assistant Professor
  • 2013.12
    -
    2014.03
    , Project Assistant Professor
  • 2017.06
    -
    2019.03
    , Assistant Professor

display all >>

Research Areas 【 display / non-display

  • Pathological medical chemistry

Qualification Acquired 【 display / non-display

  • Pharmacist

 

Published Papers & Misc 【 display / non-display

  • Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT. IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma. Nature cell biology. 2019.08; 21 (8): 1003-1014. ( PubMed, DOI )

  • Naffouje R, Grover P, Yu H, Sendilnathan A, Wolfe K, Majd N, Smith EP, Takeuchi K, Senda T, Kofuji S, Sasaki AT. Anti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story. Cancers. 2019.09; 11 (9): ( PubMed, DOI )

  • Wolfe K, Kofuji S, Yoshino H, Sasaki M, Okumura K, Sasaki AT. Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma. Biochemical and biophysical research communications. 2019.08; 516 (1): 50-56. ( PubMed, DOI )

  • Takemasu S, Nigorikawa K, Yamada M, Tsurumi G, Kofuji S, Takasuga S, Hazeki K. Phosphorylation of TMEM55B by Erk/MAPK regulates lysosomal positioning. Journal of biochemistry. 2019.08; 166 (2): 175-185. ( PubMed, DOI )

  • Takemasu S, Ito M, Morioka S, Nigorikawa K, Kofuji S, Takasuga S, Eguchi S, Nakanishi H, Matsuoka I, Sasaki J, Sasaki T, Hazeki K. Lysophosphatidylinositol-acyltransferase-1 is involved in cytosolic Ca<sup>2+</sup> oscillations in macrophages. Genes to cells : devoted to molecular & cellular mechanisms. 2019.05; 24 (5): 366-376. ( PubMed, DOI )

display all >>

Conference Activities & Talks 【 display / non-display

  • Satoshi Kofuji, Atsuo T Sasaki. A chemical-induced catastrophic vacuolization: potential anti-tumor effect . 第43回日本分子生物学会 2020.12.04

  • 小藤智史, 佐々木敦朗. GTP-metabolic reprograming that regulates the nucleolar activity and tumorigenesis . 第42回日本分子生物学会年会 2019.12.04

  • 小藤智史. GTP metabolic switch drives cellular mass anabolism for glioblastomagenesis. Jensen Symposium on Breast Cancer 2016.11

  • 小藤智史. Dynamic role of GTP metabolism in cancers. Cancer Metabolism Symposium 2016.05

  • 小藤智史. GTP metabolic switch promotes malignant growth of brain tumors. American Society for Cell Biology (ASCB) Annual Meeting 2015.12

display all >>

Awards & Honors 【 display / non-display

  • UJA Midwest Conference 2016, Presentation Award,2016.11