論文・総説 - 辻　耕平

41. Hogan M, Bahta M, Tsuji K, Nguyen TX, Cherry S, Lountos GT, Tropea JE, Zhao BM, Zhao XZ, Waugh DS, Burke TR Jr, Ulrich RG. Targeting Protein-Protein Interactions of Tyrosine Phosphatases with Microarrayed Fragment Libraries Displayed on Phosphopeptide Substrate Scaffolds. ACS combinatorial science. 2019.03; 21 (3): 158-170. ( PubMed, DOI )

42. Hymel D, Grant RA, Tsuji K, Yaffe MB, Burke TR Jr. Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors. Bioorganic & medicinal chemistry letters. 2018.10; 28 (19): 3202-3205. ( PubMed, DOI )

43. Tanegashima Kosuke, Takahashi Rena, Nuriya Hideko, Iwase Rina, Naruse Naoto, Tsuji Kohei, Shigenaga Akira, Otaka Akira, Hara Takahiko. CXCL14 Acts as a Specific Carrier of CpG DNA into Dendritic Cells and Activates Toll-like Receptor 9-mediated Adaptive Immunity EBIOMEDICINE. 2017.10; 24 247-256. ( PubMed, DOI )

44. Mitsuhiro Eto, Naoto Naruse, Kyohei Morimoto, Kosuke Yamaoka, Kohei Sato, Kohei Tsuji, Tsubasa Inokuma, Akira Shigenaga, Akira Otaka. Development of an Anilide-Type Scaffold for the Thioester Precursor N-Sulfanylethylcoumarinyl Amide. Org. Lett.. 2016.08; 18 (17): 4416-4419. ( PubMed, DOI )

45. Kohei Tsuji, Kosuke Tanegashima, Kohei Sato, Ken Sakamoto, Akira Shigenaga, Tsubasa Inokuma, Takahiko Hara, Akira Otaka. Efficient one-pot synthesis of CXCL14 and its derivative using an N-sulfanylethylanilide peptide as a peptide thioester equivalent and their biological evaluation. Bioorg. Med. Chem.. 2015.09; 23 (17): 5909-5914. ( PubMed, DOI )

46. Chiharu Mizuguchi, Fuka Ogata, Shiho Mikawa, Kohei Tsuji, Teruhiko Baba, Akira Shigenaga, Toshinori Shimanouchi, Keiichiro Okuhira, Akira Otaka, Hiroyuki Saito. Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes. J. Biol. Chem.. 2015.08; 290 (34): 20947-20959. ( PubMed, DOI )

47. Yusuke Tsuda, Akira Shigenaga, Kohei Tsuji, Masaya Denda, Kohei Sato, Keisuke Kitakaze, Takahiro Nakamura, Tsubasa Inokuma, Kohji Itoh, Akira Otaka. Development of a Chemical Methodology for the Preparation of Peptide Thioesters Applicable to Naturally Occurring Peptides Using a Sequential Quadruple Acyl Transfer System. ChemistryOpen. 2015.08; 4 (4): 448-452. ( PubMed, DOI )

48. Yuki Takechi-Haraya, Kento Tanaka, Kohei Tsuji, Yasuo Asami, Hironori Izawa, Akira Shigenaga, Akira Otaka, Hiroyuki Saito, Kohsaku Kawakami. Molecular complex composed of β-cyclodextrin-grafted Chitosan and pH-sensitive amphipathic peptide for enhancing cellular cholesterol efflux under acidic pH. Bioconjug. Chem.. 2015.03; 26 (3): 572-581. ( PubMed, DOI )

49. Emi Adachi, Asako Kosaka, Kohei Tsuji, Chiharu Mizuguchi, Hiroyuki Kawashima, Akira Shigenaga, Kohjiro Nagao, Kenichi Akaji, Akira Otaka, Hiroyuki Saito. The extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrils. FEBS Lett.. 2014.01; 588 (3): 389-394. ( PubMed, DOI )

50. Kosuke Tanegashima#, Kohei Tsuji#, Kenji Suzuki, Akira Shigenaga, Akira Otaka, Takahiko Hara (#Equally contributed). Dimeric peptides of the C-terminal region of CXCL14 function as CXCL12 inhibitors. FEBS Lett.. 2013.11; 587 (23): 3770-3775. ( PubMed, DOI )

51. Kosuke Tanegashima, Kenji Suzuki, Yuki Nakayama, Kohei Tsuji, Akira Shigenaga, Akira Otaka, Takahiko Hara. CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis. FEBS Lett.. 2013.06; 587 (12): 1731-1735. ( PubMed, DOI )

52. Ken Sakamoto, Kohei Sato, Akira Shigenaga, Kohei Tsuji, Shugo Tsuda, Hajime Hibino, Yuji Nishiuchi, Akira Otaka. Synthetic procedure for N-Fmoc amino acyl-N-sulfanylethylaniline linker as crypto-peptide thioester precursor with application to native chemical ligation. J. Org. Chem.. 2012.08; 77 (16): 6948-6958. ( PubMed, DOI )

53. Kohei Sato, Akira Shigenaga, Kohei Tsuji, Shugo Tsuda, Yoshitake Sumikawa, Ken Sakamoto, Akira Otaka. N-sulfanylethylanilide peptide as a crypto-thioester peptide. Chembiochem. 2011.08; 12 (12): 1840-1844. ( PubMed, DOI )

54. Kohei Tsuji, Akira Shigenaga, Yoshitake Sumikawa, Kosuke Tanegashima, Kohei Sato, Keisuke Aihara, Takahiko Hara, Akira Otaka. Application of N-C- or C-N-directed sequential native chemical ligation to the preparation of CXCL14 analogs and their biological evaluation. Bioorg. Med. Chem.. 2011.07; 19 (13): 4014-4020. ( PubMed, DOI )

55. Takuya Kobayakawa, Masaru Yokoyama, Kohei Tsuji, Masayuki Fujino, Masaki Kurakami, Takato Onishi, Sayaka Boku, Takahiro Ishii, Yutaro Miura, Kouki Shinohara, Yuki Kishihara, Nami Ohashi, Osamu Kotani, Tsutomu Murakami, Hironori Sato, Hirokazu Tamamura. Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins RSC ADVANCES. 2023.01; 13 (3): 2156-2167. ( PubMed, DOI )

56. Tsuji Kohei, Wang Rongyi, Owusu B. -A. Kofi, Kobayakawa Takuya, Murakami Tsutomu, Tamamura Hirokazu. Exploration of novel class anti-HIV-1 agents derived from a viral capsid protein JOURNAL OF PEPTIDE SCIENCE. 2022.08; 28

57. 辻 耕平. 医薬化学　SARS-CoV-2メインプロテアーゼ(Mpro)を標的とした阻害薬開発の動向 ファルマシア（日本薬学会 東京）. 2021.12; 57 (12): 1133. ( 医中誌 )

58. 石井 貴大, 小早川 拓也, 松田 幸樹, 辻 耕平, 吉村 和久, 満屋 裕明, 前田 賢次, 玉村 啓和. HIV感染症の根治へ向けたDAG-ラクトン誘導体の構造活性相関研究 日本薬学会年会要旨集. 2021.03; 141年会 29V03-pm04S. ( 医中誌 )

59. 村上 努, 小早川 拓也, 倉上 真樹, 横山 勝, 小谷 治, 辻 耕平, 佐藤 裕徳, 玉村 啓和. カプシド二量体化を標的とした新規抗HIV-1低分子化合物の解析 日本エイズ学会誌. 2020.11; 22 (4): 461. ( 医中誌 )

60. 玉村啓和, 小早川拓也, 辻耕平. 環状ペプチドで標的細胞へターゲティングする 「Drug Delivery System」特集“中分子創薬とDDS”. 2020.07; 35 (3): 170-180.