論文・総説 - 辻　耕平

分割表示  63 件中 21 - 40 件目  ／  全件表示 >>

  1. Kaho Matsumoto, Takeo Kuwata, William D Tolbert , Jonathan Richard, Shilei Ding, Jérémie Prévost, Shokichi Takahama, George P Judicate, Takamasa Ueno, Hirotomo Nakata, Takuya Kobayakawa, Kohei Tsuji , Hirokazu Tamamura, Amos B Smith 3rd, Marzena Pazgier, Andrés Finzi, Shuzo Matsushita. Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates. Journal of virology. 2022.12; 97 (1): e0163822. ( PubMed, DOI )

  2. Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nobuyo Higashi-Kuwata, Chika Azuma, Miyuki Nakayama, Takato Onishi, Hiroki Nakano, Naoya Wada, Miki Hori, Kouki Shinohara, Yutaro Miura, Takuma Kawada, Hironori Hayashi, Shin-Ichiro Hattori, Haydar Bulut, Debananda Das, Nobutoki Takamune, Naoki Kishimoto, Junji Saruwatari, Tadashi Okamura, Kenta Nakano, Shogo Misumi, Hiroaki Mitsuya, Hirokazu Tamamura. Potent and biostable inhibitors of the main protease of SARS-CoV-2. iScience. 2022.11; 105365. ( PubMed, DOI )

  3. Kohei Tsuji, David Hymel, Buyong Ma, Hirokazu Tamamura, Ruth Nussinov, Terrence R Burke Jr. Development of ultra-high affinity bivalent ligands targeting the polo-like kinase 1. RSC chemical biology. 2022.08; 3 (9): 1111-1120. ( PubMed, DOI )

  4. Kohei Tsuji, Takuya Kobayakawa, Kiju Konno, Ami Masuda, Kohei Takahashi, Nami Ohashi, Kazuhisa Yoshimura, Takeo Kuwata, Shuzo Matsushita, Shigeyoshi Harada, Hirokazu Tamamura. Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors. Bioorganic & Medicinal Chemistry. 2022.02; 56 116616. ( PubMed, DOI )

  5. Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nami Ohashi, Wataru Nomura & Hirokazu Tamamura. Fluorescence resonance energy transfer-based screening for protein kinase C ligands using 6-methoxynaphthalene-labeled 1,2-diacylglycerol-lactones. Organic & Biomolecular Chemistry. 2021.10; 19 (38): 8264-8271. ( PubMed, DOI )

  6. David Hymel, Kohei Tsuji, Robert A Grant, Ramesh M Chingle, Dominique L Kunciw, Michael B Yaffe, Terrence R Burke Jr. Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles. Organic & Biomolecular Chemistry. 2021.09; 19 (36): 7843-7854. ( PubMed, DOI )

  7. Takuya Kobayakawa, Chika Azuma, Yuki Watanabe, Shunsuke Sawamura, Atsuhiko Taniguchi, Yoshio Hayashi, Kohei Tsuji & Hirokazu Tamamura. Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application. The Journal of Organic Chemistry. 2021.03; 86 (7): 5091-5101. ( PubMed, DOI )

  8. Matsuda Kouki, Kobayakawa Takuya, Kariya Ryusho, Tsuchiya Kiyoto, Ryu Shoraku, Tsuji Kohei, Ishii Takahiro, Gatanaga Hiroyuki, Yoshimura Kazuhisa, Okada Seiji, Hamada Akinobu, Mitsuya Hiroaki, Tamamura Hirokazu, Maeda Kenji. A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators FRONTIERS IN MICROBIOLOGY. 2021.03; 12 636276. ( PubMed, DOI )

  9. Takuya Kobayakawa, Masaru Yokoyama, Kohei Tsuji, Masayuki Fujino, Masaki Kurakami, Sayaka Boku, Miyuki Nakayama, Moemi Kaneko, Nami Ohashi, Osamu Kotani, Tsutomu Murakami, Hironori Sato & Hirokazu Tamamura. Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins. Biomolecules. 2021.02; 11 (2): 208. ( PubMed, DOI )

  10. Takuya Kobayakawa, Kohei Tsuji, Kiju Konno, Ai Himeno, Ami Masuda, Tingting Yang, Kohei Takahashi, Yusuke Ishida, Nami Ohashi, Takeo Kuwata, Kaho Matsumoto, Kazuhisa Yoshimura, Hiromi Sakawaki, Tomoyuki Miura, Shigeyoshi Harada, Shuzo Matsushita & Hirokazu Tamamura. Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors. Journal of Medicinal Chemistry. 2021.01; 64 (3): 1481-1496. ( PubMed, DOI )

  11. Kohei Tsuji, Rongyi Wang, Takuya Kobayakawa, Kofi Baffour-Awuah Owusu, Masayuki Fujino, Moemi Kaneko, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura. Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment. Bioorganic & Medicinal Chemistry. 2021.01; 30 115923. ( PubMed, DOI )

  12. Takuya Kobayakawa, Kento Ebihara, Kohei Tsuji, Takuma Kawada, Masayuki Fujino, Yuzuna Honda, Nami Ohashi, Tsutomu Murakami, Hirokazu Tamamura. Bivalent HIV-1 fusion inhibitors based on peptidomimetics. Bioorg. Med. Chem. 2020.12; 28 (24): 115812. ( PubMed, DOI )

  13. Stephen E. Miller, Kohei Tsuji, Rachel P.M. Abrams, Terrence R. Burke, Jr., Joel P. Schneider. Uncoupling the Folding-Function Paradigm of Lytic Peptides to Deliver Impermeable Inhibitors of Intracellular Protein-Protein Interactions. J. Am. Chem. Soc. 2020.11; 142 (47): 19950-19955. ( PubMed, DOI )

  14. Kohei Tsuji, David Hymel, Terrence R. Burke, Jr.. A new genre of fluorescence recovery assay to evaluate polo-like kinase 1 ATP-competitive inhibitors. Anal. Methods: advancing methods and applications. 2020.09; 12 (36): 4418-4421. ( PubMed, DOI )

  15. Junpeng Qi, Kohei Tsuji, David Hymel, Terrence R. Burke, Jr., Michael Hudecek, Christoph Rader, Haiyong Peng. Chemically Programmable and Switchable CAR-T Therapy Angew. Chem., Int. Ed. 2020.07; 59 (29): 12178-12185 . ( PubMed, DOI )

  16. Kobayakawa T, Takano H, Ishii T, Tsuji K, Ohashi N, Nomura W, Furuta T, Tamamura H. Synthesis of hydrophilic caged DAG-lactones for chemical biology applications. Organic & biomolecular chemistry. 2020.06; 18 (22): 4217-4223. ( PubMed, DOI )

  17. Tsuji Kohei, Owusu Kofi Baffour-Awuah, Kobayakawa Takuya, Wang Rongyi, Fujino Masayuki, Kaneko Moemi, Yamamoto Naoki, Murakami Tsutomu, Tamamura Hirokazu. Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment BIOORGANIC & MEDICINAL CHEMISTRY. 2020.06; 28 (11): 115488. ( PubMed, DOI )

  18. Hwang D, Tsuji K, Park H, Burke TR Jr, Rader C. Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates. Bioconjugate chemistry. 2019.11; 30 (11): 2889-2896. ( PubMed, DOI )

  19. Kawahara Haruka, Miyashita Naoki, Tachibana Koki, Tsuda Yusuke, Morimoto Kyohei, Tsuji Kohei, Shigenaga Akira, Otaka Akira, Ishida Tatsuhiro, Okuhira Keiichiro. A Photo-Activatable Peptide Mimicking Functions of Apolipoprotein A-I BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2019.06; 42 (6): 1019-1024.

  20. Zhao XZ, Tsuji K, Hymel D, Burke TR Jr. Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors. Molecules (Basel, Switzerland). 2019.04; 24 (8): 1488. ( PubMed, DOI )

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