Daisuke Kozai, Nobutaka Numoto, Kouki Nishikawa, Akiko Kamegawa, Shohei Kawasaki, Yoko Hiroaki, Katsumasa Irie, Atsunori Oshima, Hiroyuki Hanzawa, Kousei Shimada, Yutaka Kitano, Yoshinori Fujiyoshi. Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit J Mol Biol. 2023.03; 168049. ( PubMed, DOI )

Yukihiro Tanimura, Yoko Hiroaki, Masahiro Mori, Yoshinori Fujiyoshi. Cell-based flow cytometry assay for simultaneous detection of multiple autoantibodies in a single serum sample. Anal Biochem. 2022.08; 650 114721. ( PubMed, DOI )

Katerina Naydenova, Akiko Kamegawa, Mathew J Peet, Richard Henderson, Yoshinori Fujiyoshi, Christopher J Russo. On the reduction in the effects of radiation damage to two-dimensional crystals of organic and biological molecules at liquid-helium temperature. Ultramicroscopy. 2022.07; 237 113512. ( PubMed, DOI )

Maki Kuzuya, Hidemi Hirano, Kenichi Hayashida, Masakatsu Watanabe, Kazumi Kobayashi, Tohru Terada, Md Iqbal Mahmood, Florence Tama, Kazutoshi Tani, Yoshinori Fujiyoshi, Atsunori Oshima. Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci Signal. 2022.02; 15 (720): eabg6941. ( PubMed, DOI )

Yukako Oda, Chisato Takahashi, Shota Harada, Shun Nakamura, Daxiao Sun, Kazumi Kiso, Yuko Urata, Hitoshi Miyachi, Yoshinori Fujiyoshi, Alf Honigmann, Seiichi Uchida, Yasushi Ishihama, Fumiko Toyoshima. Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation. Sci Adv. 2021.11; 7 (47): eabj6895. ( PubMed, DOI )

Hanayo Nakanishi, Tomohiro Nishizawa, Katsumori Segawa, Osamu Nureki, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe. Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep. 2020.09; 32 (13): 108208. ( PubMed, DOI )

Shimada Atsuhiro, Kozai Daisuke, Nishikawa Kouki, Fujiyoshi Yoshinori, Sho Gyokucho, Mizutani Takumi, Tani Kazutoshi. クライオ電子顕微鏡を用いたシトクロム酸化酵素とシトクロムcの複合体構造解析(The structural analysis of cytochrome c oxidase complexed with cytochrome c using cryo-electron microscopy) 生物物理. 2020.08; 60 (Suppl.1-2): S158. ( 医中誌 )

Irie Katsumasa, Shimomura Takushi, Yonekawa Yoshiki, Nagura Hitoshi, Tateyama Michihiro, Fujiyoshi Yoshinori. 天然の原核生物由来カルシウムチャネルにおけるイオン透過選択性の進化とその決定残基の同定(The selectivity determinant and evolution of a native prokaryotic voltage-dependent calcium channel) 生物物理. 2020.08; 60 (Suppl.1-2): S248. ( 医中誌 )

Hanayo Nakanishi, Katsumasa Irie, Katsumori Segawa, Kazuya Hasegawa, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe. Crystal structure of a human plasma membrane phospholipid flippase. J Biol Chem. 2020.07; 295 (30): 10180-10194. ( PubMed, DOI )

B. Burendei, R. Shinozaki, M. Watanabe, T. Terada, K. Tani, Y. Fujiyoshi and A. Oshima. Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci. Adv.. 2020.02; 6 (7): ( DOI )

Takushi Shimomura, Yoshiki Yonekawa, Hitoshi Nagura, Michihiro Tateyama, Yoshinori Fujiyoshi, Katsumasa Irie. A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence. Elife. 2020.02; 9 ( PubMed, DOI )

K. Yamamoto, V. Dubey, K. Irie, H. Nakanishi, H. Khandelia, Y. Fujiyoshi and K. Abe. A single K+-binding site in the crystal structure of the gastric proton pump. eLife. 2019.08; 8 ( DOI )

Shun Nakamura, Katsumasa Irie, Hiroo Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Yasunori Saitoh, Atsushi Tamura, Sachiko Tsukita & Yoshinori Fujiyoshi. Morphologic determinant of tight junctions revealed by claudin-3 structures Nature Communications. 2019.02; 10 816. ( DOI )

Hiroki Yamaguchi, Akiko Kamegawa, Kunio Nakata, Tatsuki Kashiwagi, Toshimi Mizukoshi, Yoshinori Fujiyoshi, Kazutoshi Tani. Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy Journal of Structural Biology. 2019.01; 205 (1): 11-21. ( DOI )

藤吉 好則. クライオ電子顕微鏡が激変させたタンパク質の立体構造解析技術 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 84. ( 医中誌 )

中西 華代, 入江 克雅, 瀬川 勝盛, 長田 重一, 長谷川 和也, 藤吉 好則, 阿部 一啓. ヒト細胞膜フリッパーゼATP11CのX線結晶構造解析 日本生化学会大会プログラム・講演要旨集. 2020.09; 93回 [P-132]. ( 医中誌 )

山口 浩輝, 亀川 亜希子, 中田 國夫, 柏木 立己, 高橋 一敏, 田上 宇乃, 巽 萌美, 水越 利巳, 宮野 博, 藤吉 好則, 谷 一寿. 酵素には世界と未来を変える力がある-今こそ酵素を見つめ直す2020-　クライオ電子顕微鏡によるロイシン脱水素酵素の耐熱化機構解明 日本生化学会大会プログラム・講演要旨集. 2020.09; 93回 [3S08m-04]. ( 医中誌 )

Abe K, Irie K, Nakanishi H, Suzuki H, Fujiyoshi Y. Crystal structures of the gastric proton pump. Nature. 2018.04; 556 (7700): 214-218. ( PubMed, DOI )

Nakamura S, Fujiyoshi Y, Irie K. Enhancement of the thermostability of mouse claudin-3 on complex formation with the carboxyl-terminal region of Clostridium perfringens enterotoxin improves crystal quality. Acta crystallographica. Section F, Structural biology communications. 2018.03; 74 (Pt 3): 150-155. ( PubMed, DOI )

Irie K, Haga Y, Shimomura T, Fujiyoshi Y. Optimized expression and purification of NavAb provide the structural insight into the voltage dependence. FEBS letters. 2018.01; 592 (2): 274-283. ( PubMed, DOI )

Shihoya W, Nishizawa T, Yamashita K, Inoue A, Hirata K, Kadji FMN, Okuta A, Tani K, Aoki J, Fujiyoshi Y, Doi T, Nureki O. X-ray structures of endothelin ET_B receptor bound to clinical antagonist bosentan and its analog. Nature structural & molecular biology. 2017.09; 24 (9): 758-764. ( PubMed, DOI )

Abe K, Shimokawa J, Naito M, Munson K, Vagin O, Sachs G, Suzuki H, Tani K, Fujiyoshi Y. The cryo-EM structure of gastric H⁺,K⁺-ATPase with bound BYK99, a high-affinity member of K⁺-competitive, imidazo[1,2-a]pyridine inhibitors. Scientific reports. 2017.07; 7 (1): 6632. ( PubMed, DOI )

Suzuki H, Tani K, Fujiyoshi Y. Crystal structures of claudins: insights into their intermolecular interactions. Annals of the New York Academy of Sciences. 2017.06; 1397 (1): 25-34. ( PubMed, DOI )

Oshima A, Tani K, Fujiyoshi Y. Atomic structure of the innexin-6 gap junction channel determined by cryo-EM. Nature communications. 2016.12; 7 13681. ( PubMed, DOI )

Shihoya W, Nishizawa T, Okuta A, Tani K, Dohmae N, Fujiyoshi Y, Nureki O, Doi T. Activation mechanism of endothelin ET_B receptor by endothelin-1. Nature. 2016.09; 537 (7620): 363-368. ( PubMed, DOI )

Shimomura T, Irie K, Fujiyoshi Y. Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics. The FEBS journal. 2016.08; 283 (15): 2881-2895. ( PubMed, DOI )

Abe K, Fujiyoshi Y. Cryo-electron microscopy for structure analyses of membrane proteins in the lipid bilayer. Current opinion in structural biology. 2016.08; 39 71-78. ( PubMed, DOI )

Okuta A, Tani K, Nishimura S, Fujiyoshi Y, Doi T. Thermostabilization of the Human Endothelin Type B Receptor. Journal of molecular biology. 2016.06; 428 (11): 2265-2274. ( PubMed, DOI )

Kamegawa A, Hiroaki Y, Tani K, Fujiyoshi Y. Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide. Microscopy (Oxford, England). 2016.04; 65 (2): 177-184. ( PubMed, DOI )

Nagura H, Doi T, Fujiyoshi Y. Characterization of physiological phenotypes of dentate gyrus synapses of PDZ1/2 domain-deficient PSD-95-knockin mice. The European journal of neuroscience. 2016.03; 43 (5): 618-625. ( PubMed, DOI )

Oshima A, Matsuzawa T, Murata K, Tani K, Fujiyoshi Y. Hexadecameric structure of an invertebrate gap junction channel. Journal of molecular biology. 2016.03; 428 (6): 1227-1236. ( PubMed, DOI )

Bando Y, Irie K, Shimomura T, Umeshima H, Kushida Y, Kengaku M, Fujiyoshi Y, Hirano T, Tagawa Y. Control of Spontaneous Ca2+ Transients Is Critical for Neuronal Maturation in the Developing Neocortex. Cerebral cortex (New York, N.Y. : 1991). 2016.01; 26 (1): 106-117. ( PubMed, DOI )

Tanaka H, Yamamoto Y, Kashihara H, Yamazaki Y, Tani K, Fujiyoshi Y, Mineta K, Takeuchi K, Tamura A, Tsukita S. Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Molecular and cellular biology. 2016.01; 36 (6): 954-964. ( PubMed, DOI )

Hauer F, Gerle C, Fischer N, Oshima A, Shinzawa-Itoh K, Shimada S, Yokoyama K, Fujiyoshi Y, Stark H. GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM. Structure (London, England : 1993). 2015.09; 23 (9): 1769-1775. ( PubMed, DOI )

Minatohara K, Murata Y, Fujiyoshi Y, Doi T. An intracellular domain with a novel sequence regulates cell surface expression and synaptic clustering of leucine-rich repeat transmembrane proteins in hippocampal neurons. Journal of neurochemistry. 2015.08; 134 (4): 618-628. ( PubMed, DOI )

Jiko C, Davies KM, Shinzawa-Itoh K, Tani K, Maeda S, Mills DJ, Tsukihara T, Fujiyoshi Y, Kühlbrandt W, Gerle C. Bovine F1Fo ATP synthase monomers bend the lipid bilayer in 2D membrane crystals. eLife. 2015.03; 4 e06119. ( PubMed, DOI )

Saitoh Y, Suzuki H, Tani K, Nishikawa K, Irie K, Ogura Y, Tamura A, Tsukita S, Fujiyoshi Y. Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin. Science (New York, N.Y.). 2015.02; 347 (6223): 775-778. ( PubMed, DOI )

Suzuki H, Tani K, Tamura A, Tsukita S, Fujiyoshi Y. Model for the architecture of claudin-based paracellular ion channels through tight junctions. Journal of molecular biology. 2015.01; 427 (2): 291-297. ( PubMed, DOI )

Fujiyoshi Y. Development of the field of structural physiology. Proceedings of the Japan Academy. Series B, Physical and biological sciences. 2015; 91 (9): 447-468. ( PubMed, DOI )

Abe K, Tani K, Fujiyoshi Y. Systematic comparison of molecular conformations of H+,K+-ATPase reveals an important contribution of the A-M2 linker for the luminal gating. The Journal of biological chemistry. 2014.10; 289 (44): 30590-30601. ( PubMed, DOI )

Tani K, Fujiyoshi Y. Water channel structures analysed by electron crystallography. Biochimica et biophysica acta. 2014.05; 1840 (5): 1605-1613. ( PubMed, DOI )

Suzuki H, Nishizawa T, Tani K, Yamazaki Y, Tamura A, Ishitani R, Dohmae N, Tsukita S, Nureki O, Fujiyoshi Y. Crystal structure of a claudin provides insight into the architecture of tight junctions. Science (New York, N.Y.). 2014.04; 344 (6181): 304-307. ( PubMed, DOI )

Morito D, Nishikawa K, Hoseki J, Kitamura A, Kotani Y, Kiso K, Kinjo M, Fujiyoshi Y, Nagata K. Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state. Scientific reports. 2014.03; 4 4442. ( PubMed, DOI )

Yang F, Abe K, Tani K, Fujiyoshi Y. Carbon sandwich preparation preserves quality of two-dimensional crystals for cryo-electron microscopy. Microscopy (Oxford, England). 2013.12; 62 (6): 597-606. ( PubMed, DOI )

Tsai CJ, Tani K, Irie K, Hiroaki Y, Shimomura T, McMillan DG, Cook GM, Schertler GF, Fujiyoshi Y, Li XD. Two alternative conformations of a voltage-gated sodium channel. Journal of molecular biology. 2013.11; 425 (22): 4074-4088. ( PubMed, DOI )

Tani K, Arthur CP, Tamakoshi M, Yokoyama K, Mitsuoka K, Fujiyoshi Y, Gerle C. Visualization of two distinct states of disassembly in the bacterial V-ATPase from Thermus thermophilus. Microscopy (Oxford, England). 2013.08; 62 (4): 467-474. ( PubMed, DOI )

Fujiyoshi Y, Tanji T, Osakabe N, Hirayama T. Special Issue: "Tribute to Akira Tonomura". Foreword. Microscopy (Oxford, England). 2013.06; 62 Suppl 1 S1. ( PubMed, DOI )

Oshima A, Matsuzawa T, Nishikawa K, Fujiyoshi Y. Oligomeric structure and functional characterization of Caenorhabditis elegans Innexin-6 gap junction protein. The Journal of biological chemistry. 2013.04; 288 (15): 10513-10521. ( PubMed, DOI )

Mori H, Fujiyoshi Y. Preface on the occasion of the inauguration issue of Microscopy. Microscopy (Oxford, England). 2013.02; 62 (1): 1-2. ( PubMed, DOI )

Goda M, Fujiyoshi Y, Sugimoto M, Fujii R. Novel dichromatic chromatophores in the integument of the mandarin fish Synchiropus splendidus. The Biological bulletin. 2013.02; 224 (1): 14-17. ( PubMed, DOI )

Minatohara K, Ichikawa SH, Seki T, Fujiyoshi Y, Doi T. Ligand binding of PDZ domains has various roles in the synaptic clustering of SAP102 and PSD-95. Neuroscience letters. 2013.01; 533 44-49. ( PubMed, DOI )

Fujiyoshi Y. Low dose techniques and cryo-electron microscopy. Methods in molecular biology (Clifton, N.J.). 2013; 955 103-118. ( PubMed, DOI )

Suzuki H, Ito Y, Yamazaki Y, Mineta K, Uji M, Abe K, Tani K, Fujiyoshi Y, Tsukita S. The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat. Nature communications. 2013; 4 1766. ( PubMed, DOI )

Fujiyoshi Y. Future directions of electron crystallography. Methods in molecular biology (Clifton, N.J.). 2013; 955 551-568. ( PubMed, DOI )

Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, Tamura H, Shiosaka S, Suzuki H, Miyakawa T, Fujiyoshi Y, Doi T. Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. Molecular brain. 2012.12; 5 43. ( PubMed, DOI )

Abe K, Tani K, Friedrich T, Fujiyoshi Y. Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site. Proceedings of the National Academy of Sciences of the United States of America. 2012.11; 109 (45): 18401-18406. ( PubMed, DOI )

Unwin N, Fujiyoshi Y. Gating movement of acetylcholine receptor caught by plunge-freezing. Journal of molecular biology. 2012.10; 422 (5): 617-634. ( PubMed, DOI )

Irie K, Shimomura T, Fujiyoshi Y. The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate. Nature communications. 2012.04; 3 793. ( PubMed, DOI )

Rico F, Oshima A, Hinterdorfer P, Fujiyoshi Y, Scheuring S. Two-dimensional kinetics of inter-connexin interactions from single-molecule force spectroscopy. Journal of molecular biology. 2011.09; 412 (1): 72-79. ( PubMed, DOI )

Goda M, Ohata M, Ikoma H, Fujiyoshi Y, Sugimoto M, Fujii R. Integumental reddish-violet coloration owing to novel dichromatic chromatophores in the teleost fish, Pseudochromis diadema. Pigment cell & melanoma research. 2011.08; 24 (4): 614-617. ( PubMed, DOI )

Ohta Y, Nishikawa K, Hiroaki Y, Fujiyoshi Y. Electron tomographic analysis of gap junctions in lateral giant fibers of crayfish. Journal of structural biology. 2011.07; 175 (1): 49-61. ( PubMed, DOI )

Wakao S, Kitada M, Kuroda Y, Shigemoto T, Matsuse D, Akashi H, Tanimura Y, Tsuchiyama K, Kikuchi T, Goda M, Nakahata T, Fujiyoshi Y, Dezawa M. Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 2011.06; 108 (24): 9875-9880. ( PubMed, DOI )

Yakata K, Tani K, Fujiyoshi Y. Water permeability and characterization of aquaporin-11. Journal of structural biology. 2011.05; 174 (2): 315-320. ( PubMed, DOI )

Fujiyoshi Y. Structural physiology based on electron crystallography. Protein science : a publication of the Protein Society. 2011.05; 20 (5): 806-817. ( PubMed, DOI )

Shimomura T, Irie K, Nagura H, Imai T, Fujiyoshi Y. Arrangement and mobility of the voltage sensor domain in prokaryotic voltage-gated sodium channels. The Journal of biological chemistry. 2011.03; 286 (9): 7409-7417. ( PubMed, DOI )

Oshima A, Tani K, Toloue MM, Hiroaki Y, Smock A, Inukai S, Cone A, Nicholson BJ, Sosinsky GE, Fujiyoshi Y. Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels. Journal of molecular biology. 2011.01; 405 (3): 724-735. ( PubMed, DOI )

Abe K, Tani K, Fujiyoshi Y. Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant. Nature communications. 2011.01; 2 155. ( PubMed, DOI )

Fujiyoshi Y. Electron crystallography for structural and functional studies of membrane proteins. Journal of electron microscopy. 2011; 60 Suppl 1 S149-59. ( PubMed, DOI )

Mitsuma T, Tani K, Hiroaki Y, Kamegawa A, Suzuki H, Hibino H, Kurachi Y, Fujiyoshi Y. Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation. Journal of molecular biology. 2010.10; 402 (4): 669-681. ( PubMed, DOI )

Matsuse D, Kitada M, Kohama M, Nishikawa K, Makinoshima H, Wakao S, Fujiyoshi Y, Heike T, Nakahata T, Akutsu H, Umezawa A, Harigae H, Kira J, Dezawa M. Human umbilical cord-derived mesenchymal stromal cells differentiate into functional Schwann cells that sustain peripheral nerve regeneration. Journal of neuropathology and experimental neurology. 2010.09; 69 (9): 973-985. ( PubMed, DOI )

Nagura H, Irie K, Imai T, Shimomura T, Hige T, Fujiyoshi Y. Evidence for lateral mobility of voltage sensors in prokaryotic voltage-gated sodium channels. Biochemical and biophysical research communications. 2010.08; 399 (3): 341-346. ( PubMed, DOI )

Kuroda Y, Kitada M, Wakao S, Nishikawa K, Tanimura Y, Makinoshima H, Goda M, Akashi H, Inutsuka A, Niwa A, Shigemoto T, Nabeshima Y, Nakahata T, Nabeshima Y, Fujiyoshi Y, Dezawa M. Unique multipotent cells in adult human mesenchymal cell populations. Proceedings of the National Academy of Sciences of the United States of America. 2010.05; 107 (19): 8639-8643. ( PubMed, DOI )

Abe K, Tani K, Fujiyoshi Y. Structural and functional characterization of H+, K+-ATPase with bound fluorinated phosphate analogs. Journal of structural biology. 2010.04; 170 (1): 60-68. ( PubMed, DOI )

Irie K, Kitagawa K, Nagura H, Imai T, Shimomura T, Fujiyoshi Y. Comparative study of the gating motif and C-type inactivation in prokaryotic voltage-gated sodium channels. The Journal of biological chemistry. 2010.02; 285 (6): 3685-3694. ( PubMed, DOI )

Abe K, Tani K, Nishizawa T, Fujiyoshi Y. [Novel ratchet mechanism of gastric H(+), K(+)-ATPase revealed by electron crystallography of two-dimensional crystals]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2010.02; 130 (2): 205-210. ( PubMed, DOI )

Schenk AD, Hite RK, Engel A, Fujiyoshi Y, Walz T. Electron crystallography and aquaporins. Methods in enzymology. 2010; 483 91-119. ( PubMed, DOI )

Inutsuka A, Goda M, Fujiyoshi Y. Calyculin A-induced neurite retraction is critically dependent on actomyosin activation but not on polymerization state of microtubules. Biochemical and biophysical research communications. 2009.12; 390 (4): 1160-1166. ( PubMed, DOI )

Noma K, Kimura K, Minatohara K, Nakashima H, Nagao Y, Mizoguchi A, Fujiyoshi Y. Triple N-glycosylation in the long S5-P loop regulates the activation and trafficking of the Kv12.2 potassium channel. The Journal of biological chemistry. 2009.11; 284 (48): 33139-33150. ( PubMed, DOI )

Kuwahara Y, Unzai S, Nagata T, Hiroaki Y, Yokoyama H, Matsui I, Ikegami T, Fujiyoshi Y, Hiroaki H. Unusual thermal disassembly of the SPFH domain oligomer from Pyrococcus horikoshii. Biophysical journal. 2009.10; 97 (7): 2034-2043. ( PubMed, DOI )

Fujiyoshi Y. [Observation of molecular structure of membrane proteins]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009.08; 54 (10): 1300-1306. ( PubMed )

Abe K, Tani K, Nishizawa T, Fujiyoshi Y. Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle. The EMBO journal. 2009.06; 28 (11): 1637-1643. ( PubMed, DOI )

Tani K, Mitsuma T, Hiroaki Y, Kamegawa A, Nishikawa K, Tanimura Y, Fujiyoshi Y. Mechanism of aquaporin-4's fast and highly selective water conduction and proton exclusion. Journal of molecular biology. 2009.06; 389 (4): 694-706. ( PubMed, DOI )

Tanimura Y, Hiroaki Y, Fujiyoshi Y. Acetazolamide reversibly inhibits water conduction by aquaporin-4. Journal of structural biology. 2009.04; 166 (1): 16-21. ( PubMed, DOI )

Maeda S, Nakagawa S, Suga M, Yamashita E, Oshima A, Fujiyoshi Y, Tsukihara T. Structure of the connexin 26 gap junction channel at 3.5 A resolution. Nature. 2009.04; 458 (7238): 597-602. ( PubMed, DOI )

Mio K, Ogura T, Yamamoto T, Hiroaki Y, Fujiyoshi Y, Kubo Y, Sato C. Reconstruction of the P2X(2) receptor reveals a vase-shaped structure with lateral tunnels above the membrane. Structure (London, England : 1993). 2009.02; 17 (2): 266-275. ( PubMed, DOI )

Walz T, Fujiyoshi Y, Engel A. The AQP structure and functional implications. Handbook of experimental pharmacology. 2009; (190): 31-56. ( PubMed, DOI )

Tani K, Hiroaki Y, Fujiyoshi Y. [Aquaporin-4]. Rinsho shinkeigaku = Clinical neurology. 2008.11; 48 (11): 941-944. ( PubMed )

Fujiyoshi Y, Unwin N. Electron crystallography of proteins in membranes. Current opinion in structural biology. 2008.10; 18 (5): 587-592. ( PubMed, DOI )

Sakisaka T, Yamamoto Y, Mochida S, Nakamura M, Nishikawa K, Ishizaki H, Okamoto-Tanaka M, Miyoshi J, Fujiyoshi Y, Manabe T, Takai Y. Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release. The Journal of cell biology. 2008.10; 183 (2): 323-337. ( PubMed, DOI )

Iwasaki K, Miyazaki N, Hammar L, Zhu Y, Omura T, Wu B, Sjöborg F, Yonekura K, Murata K, Namba K, Caspar DL, Fujiyoshi Y, Cheng RH. Pleomorphic configuration of the trimeric capsid proteins of Rice dwarf virus that allows formation of both the outer capsid and tubular crystals. Journal of molecular biology. 2008.10; 383 (1): 252-265. ( PubMed, DOI )

Nishizawa T, Abe K, Tani K, Fujiyoshi Y. Structural analysis of 2D crystals of gastric H+,K+-ATPase in different states of the transport cycle. Journal of structural biology. 2008.05; 162 (2): 219-228. ( PubMed, DOI )

Oshima A, Tani K, Hiroaki Y, Fujiyoshi Y, Sosinsky GE. Projection structure of a N-terminal deletion mutant of connexin 26 channel with decreased central pore density. Cell communication & adhesion. 2008.05; 15 (1): 85-93. ( PubMed, DOI )

Hayakawa S, Mori M, Okuta A, Kamegawa A, Fujiyoshi Y, Yoshiyama Y, Mitsuoka K, Ishibashi K, Sasaki S, Hattori T, Kuwabara S. Neuromyelitis optica and anti-aquaporin-4 antibodies measured by an enzyme-linked immunosorbent assay. Journal of neuroimmunology. 2008.05; 196 (1-2): 181-187. ( PubMed, DOI )

Suzuki H, Nishikawa K, Hiroaki Y, Fujiyoshi Y. Formation of aquaporin-4 arrays is inhibited by palmitoylation of N-terminal cysteine residues. Biochimica et biophysica acta. 2008.04; 1778 (4): 1181-1189. ( PubMed, DOI )

Suzuki H, Kurooka M, Hiroaki Y, Fujiyoshi Y, Kaneda Y. Sendai virus F glycoprotein induces IL-6 production in dendritic cells in a fusion-independent manner. FEBS letters. 2008.04; 582 (9): 1325-1329. ( PubMed, DOI )

Engel A, Fujiyoshi Y, Gonen T, Walz T. Junction-forming aquaporins. Current opinion in structural biology. 2008.04; 18 (2): 229-235. ( PubMed, DOI )

Toei M, Gerle C, Nakano M, Tani K, Gyobu N, Tamakoshi M, Sone N, Yoshida M, Fujiyoshi Y, Mitsuoka K, Yokoyama K. Dodecamer rotor ring defines H+/ATP ratio for ATP synthesis of prokaryotic V-ATPase from Thermus thermophilus. Proceedings of the National Academy of Sciences of the United States of America. 2007.12; 104 (51): 20256-20261. ( PubMed, DOI )

Hirai T, Mitsuoka K, Kidera A, Fujiyoshi Y. Simulation of charge effects on density maps obtained by high-resolution electron crystallography. Journal of electron microscopy. 2007.08; 56 (4): 131-140. ( PubMed, DOI )

Oshima A, Tani K, Hiroaki Y, Fujiyoshi Y, Sosinsky GE. Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule. Proceedings of the National Academy of Sciences of the United States of America. 2007.06; 104 (24): 10034-10039. ( PubMed, DOI )

Yakata K, Hiroaki Y, Ishibashi K, Sohara E, Sasaki S, Mitsuoka K, Fujiyoshi Y. Aquaporin-11 containing a divergent NPA motif has normal water channel activity. Biochimica et biophysica acta. 2007.03; 1768 (3): 688-693. ( PubMed, DOI )

Mio K, Ogura T, Kiyonaka S, Hiroaki Y, Tanimura Y, Fujiyoshi Y, Mori Y, Sato C. The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas. Journal of molecular biology. 2007.03; 367 (2): 373-383. ( PubMed, DOI )

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