Graduating School 【 display / non-display 】
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Nagoya University, Faculty of Science, 1971.03, Graduated
Graduate School 【 display / non-display 】
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Kyoto University, Graduate School, Division of Natural Science, Doctor's Course, 1979.03, Accomplished credits for doctoral program
Campus Career 【 display / non-display 】
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2019.04-NowTokyo Medical and Dental University, , , Distinguished Professor
Research Areas 【 display / non-display 】
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Structural biochemistry
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Cell biology
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Molecular biology
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Biophysics
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Drug development chemistry
Published Papers & Misc 【 display / non-display 】
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B. Burendei, R. Shinozaki, M. Watanabe, T. Terada, K. Tani, Y. Fujiyoshi and A. Oshima. Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci. Adv.. 2020.02; 6 (7): ( DOI )
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K. Yamamoto, V. Dubey, K. Irie, H. Nakanishi, H. Khandelia, Y. Fujiyoshi and K. Abe. A single K+-binding site in the crystal structure of the gastric proton pump. eLife. 2019.08; 8 ( DOI )
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Shun Nakamura, Katsumasa Irie, Hiroo Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Yasunori Saitoh, Atsushi Tamura, Sachiko Tsukita & Yoshinori Fujiyoshi. Morphologic determinant of tight junctions revealed by claudin-3 structures Nature Communications. 2019.02; 10 816. ( DOI )
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Hiroki Yamaguchi, Akiko Kamegawa, Kunio Nakata, Tatsuki Kashiwagi, Toshimi Mizukoshi, Yoshinori Fujiyoshi, Kazutoshi Tani. Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy Journal of Structural Biology. 2019.01; 205 (1): 11-21. ( DOI )
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Abe K, Irie K, Nakanishi H, Suzuki H, Fujiyoshi Y. Crystal structures of the gastric proton pump. Nature. 2018.04; 556 (7700): 214-218. ( PubMed, DOI )
Conference Activities & Talks 【 display / non-display 】
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藤吉好則. Cryo-EM changes structural biology [Tutorial Lecture]. ALC '19 2019.10.23
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藤吉好則. Structure-guided drug development by cryo-EM [Plenary Lecture]. International Symposium on Diffraction Structural Biology 2019 2019.10.18
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藤吉好則. Drug rescuing based on structure analyses by cryo-EM. インベスターR&D Day 2019.09.12
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Yoshinori Fujiyoshi. Structural physiology of membrane proteins. Special Seminar at MRC-LMB 2018.09.13 Cambridge (UK)
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Yoshinori Fujiyoshi. Structure-guided drug development by Cryo-EM [Keynote]. The official Opening of the electron Bio-Imaging Centre (eBIC) at Diamond Light Source 2018.09.12 Oxfordshire (UK)