Personnel Information

写真a

HARAZONO Yosuke


Job title

Assistant Professor
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Campus Career 【 display / non-display 】

  • 2019.04
    -
    2019.12
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Maxillofacial and Neck Reconstruction， Maxillofacial Surgery， Project Assistant Professor
  • 2019.04
    -
    2020.03
    Tokyo Medical and Dental University， (Old Organization)Dental Hospital， Hospital Departments， Clinics for Oral and Maxillofacial Rehabilitation， Oral Surgery， Project Assistant Professor
  • 2020.04
    -
    2021.03
    Tokyo Medical and Dental University， (Old Organization)Dental Hospital， Hospital Departments， Clinics for Oral and Maxillofacial Rehabilitation， Oral Surgery， Project Assistant Professor
  • 2021.04
    -
    2021.09
    Tokyo Medical and Dental University， (Old Organization)Dental Hospital， Hospital Departments， Clinics for Oral and Maxillofacial Rehabilitation， Oral Surgery， Assistant Professor
  • 2021.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Maxillofacial and Neck Reconstruction， Maxillofacial Surgery， Assistant Professor
  • 2021.10
    -
    Now
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Dentistry， Department of Oral and Maxillofacial Surgery， Oral and Maxillofacial Surgery， Assistant Professor

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Qualification Acquired 【 display / non-display 】

  • International Board for Certification of Specialists in Oral and Maxillofacial Surgery

  • Dentist

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Research Theme 【 display / non-display 】

  • Retrospective analysis of schwannoma in the oral and maxillofacial region clinicopathological characteristics and specific pathology of ancient change, 2020 - 2021

  • miR-655 is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2, 2010.04 - 2013.03

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Published Papers & Misc 【 display / non-display 】

  1. TONOUCHI Erina, MORITA Kei‒ichi, HARAZONO Yosuke, ANZAI Eri, TAKAHARA Namiaki and YODA Tetsuya. Double level fixation of premaxilla during alveolar bone grafting with premaxillary osteotomy in patients with bilateral cleft lip and palate The Journal of the Stomatological Society, Japan. 2024.03;

  2. Yosuke Harazono, Hiroyuki Yoshitake, Yuki Fukawa, Tohru Ikeda, Tetsuya Yoda. Osteoblastoma in the mandible of an older adult patient without FOS gene rearrangement: A case report and literature review Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2024.01;

  3. Noboru Maruta,Kei-ichi Morita,Yosuke Harazono,Eri Anzai,Yu Akaike,Kotaro Yamazaki,Erina Tonouchi,Tetsuya Yoda. Automatic machine learning-based classification of mandibular third molar impaction status Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2023.07; 35 (4): 327-334.

  4. Otsuru M, Yanamoto S, Yamada SI, Nakashiro K, Harazono Y, Kohgo T, Nakamura M, Nomura T, Kasamatsu A, Tanaka S, Kirita T, Kioi M, Ogawa M, Sasaki M, Ota Y, Umeda M. Radiotherapy Plus Cetuximab for Squamous Cell Carcinoma of the Oral Cavity: A Multicenter Retrospective Study of 79 Patients in Japan. International journal of environmental research and public health. 2023.03; 20 (5): ( PubMed, DOI )

  5. Y Harazono, K Morita, E Tonouchi, E Anzai, N Takahara, T Kohmoto, I Imoto, T Yoda. TP63 mutation mapping information in TP63 mutation-associated syndromes Advances in Oral and Maxillofacial Surgery. 2022.01; 5

  6. Shibata Eri, Morita Kei-ichi, Kayamori Kou, Tange Shoichiro, Shibata Hiroki, Harazono Yosuke, Michi Yasuyuki, Ikeda Tohru, Harada Hiroyuki, Imoto Issei, Yoda Tetsuya. Detection of novel fusion genes by next-generation sequencing-based targeted RNA sequencing analysis in adenoid cystic carcinoma of head and neck ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2021.10; 132 (4): 426-433. ( DOI )

  7. Iwanaga J, Kim HJ, Wysiadecki G, Obata K, Harazono Y, Ibaragi S, Tubbs SR.. Localizing the nerve to the mylohyoid using the mylohyoid triangle. Anat Cell Biol. 2021.09; 54 (3): 304-307. ( PubMed, DOI )

  8. Harazono Y, Kayamori K, Sakamoto J, Akaike Y, Kurasawa Y, Tsushima F, Sasaki Y, Harada H, Yoda T. A retrospective analysis of schwannoma in the oral maxillofacial region: the clinicopathological characteristics and the specific pathology of ancient change British Journal of Oral & Maxillofacial Surgery. 2021.07; ( PubMed, DOI )

  9. Samira Bernardino Ramos do Prado, Tânia Misuzu Shiga, Yosuke Harazono, Victor A Hogan, Avraham Raz, Nicholas C Carpita, João Paulo Fabi. Migration and proliferation of cancer cells in culture are differentially affected by molecular size of modified citrus pectin. Carbohydr Polym. 2019.05; 211 141-151. ( PubMed, DOI )

  10. Samira Bernardino Ramos do Prado, Gabrielle Fernandez Ferreira, Yosuke Harazono, Tânia Misuzu Shiga, Avraham Raz, Nicholas C Carpita, João Paulo Fabi. Ripening-induced chemical modifications of papaya pectin inhibit cancer cell proliferation. Sci Rep. 2017.11; 7 (1): 16564. ( PubMed, DOI )

  11. Kosei Nakajima, Dhong Hyo Kho, Takashi Yanagawa, Yosuke Harazono, Victor Hogan, Wei Chen, Rouba Ali-Fehmi, Rohit Mehra, Avraham Raz. Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis. Cancer Res.. 2016.03; 76 (6): 1391-1402. ( PubMed, DOI )

  12. Yosuke Harazono, Dhong Hyo Kho, Vitaly Balan, Kosei Nakajima, Victor Hogan, Avraham Raz. Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling. Oncotarget. 2015.08; 6 (23): 19592-19604. ( PubMed, DOI )

  13. Tianpeng Zhang, Dhong Hyo Kho, Ying Wang, Yosuke Harazono, Kosei Nakajima, Youming Xie, Avraham Raz. Gp78, an E3 ubiquitin ligase acts as a gatekeeper suppressing nonalcoholic steatohepatitis (NASH) and liver cancer. PLoS ONE. 2015.03; 10 (3): e0118448. ( PubMed, DOI )

  14. Yosuke Harazono, Masashi Yamashiro, Hiroyuki Yoshitake, Kou Kayamori, Toshiyuki Izumo, Kiyoshi Harada. A case of highly suspected small cell osteosarcoma in the mandible Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2015.01;

  15. Kosei Nakajima, Dhong Hyo Kho, Takashi Yanagawa, Yosuke Harazono, Xiaoge Gao, Victor Hogan, Avraham Raz. Galectin-3 inhibits osteoblast differentiation through notch signaling. Neoplasia. 2014.11; 16 (11): 939-949. ( PubMed, DOI )

  16. Yosuke Harazono, Dhong Hyo Kho, Vitaly Balan, Kosei Nakajima, Tianpeng Zhang, Victor Hogan, Avraham Raz. Galectin-3 leads to attenuation of apoptosis through Bax heterodimerization in human thyroid carcinoma cells. Oncotarget. 2014.10; 5 (20): 9992-10001. ( PubMed, DOI )

  17. Y Harazono, K Nakajima, A Raz. Why anti-Bcl-2 clinical trials fail: a solution. Cancer Metastasis Rev.. 2014.03; 33 (1): 285-294. ( PubMed, DOI )

  18. Harazono Y, Muramatsu T, Endo H, Uzawa N, Kawano T, Harada K, Inazawa J, Kozaki K. miR-655 is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2 PLoS One. 2013.05;

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Books etc 【 display / non-display 】

  1. Joe Iwanaga, R.Shane Tubbs, Jingo Kusukawa, Shin, Daniel E., Solomon, Charles S., Tomaszewska, Iwona M., He, Puhan, Soichiro Ibaragi, Katsuichiro Maruo, Tomaszewska, Iwona M., Tatsuo Okui, Yosuke Harazono, Norie Yoshioka, Shogo Kikuta, Koichi Watanabe, Ramdhan, Rebecca C., Tsuyoshi Tanaka, Yasuhiko Kamura, Masayoshi Uezono. Anatomical Variations in Clinical Dentistry . 2019 Anatomy and Variations of the Submandibular Fossa (ISBN : 978-3-319-97961-8)

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Conference Activities & Talks 【 display / non-display 】

  1. Harazono Y, Kozaki K, Muramatsu T, Endo H, Uzawa N, Kawano T, Harada K, Inazawa J. miR-655 is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2.. 9th Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association 2013.02

  2. Harazono Y, Kozaki K, Muramatsu T, Kurasawa Y, Teruo A, Inazawa J. Exploration of EMT-related microRNAs using function-based screening with expression analysis of E-cadherin in Panc1 line. American Association for Cancer Research, 103th Annual Meeting 2012.04

  3. Harazono Y, Kozaki K, Muramatsu T, Kurasawa Y, Yamashiro M, Inazawa J. Exploration of MET-induced microRNA using function-based screening with expression analysis of E-cadherin. 平成23年度難治疾患研究所研究発表会 2012.03.08

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Performance of duties 【 display / non-display 】

  • ，2024.04 - 2025.03

  • ，2023.07 - Now

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