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Takahashi Kei, Yamada Tetsuya, Hosaka Shinichiro, Kaneko Keizo, Asai Yoichiro, Munakata Yuichiro, Seike Junro, Horiuchi Takahiro, Kodama Shinjiro, Izumi Tomohito, Sawada Shojiro, Hoshikawa Kyoko, Inoue Jun, Masamune Atsushi, Ueno Yoshiyuki, Imai Junta, Katagiri Hideki. Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages CELL REPORTS. 2023.05; 42 (5): 112415. ( PubMed, DOI )

Beppu Hiroko, Fukuda Tatsuya, Otsubo Naoya, Kawanishi Tomoko, Ogawa Toshie, Abe Yasutomo, Endo Mariko, Hanawa Tomohide, Sugita Chise, Kikkawa Yoshiaki, Hatakeyama Shuji, Yamada Tetsuya, Wakai Sachiko. Serum chemokine CC-motif ligand 17 is a predictive marker of severe COVID-19 in haemodialysis patients: A retrospective observational study NEPHROLOGY. 2023.04; 28 (4): 240-248. ( PubMed, DOI )

Otsubo Naoya, Fukuda Tatsuya, Beppu Hiroko, Maki Chisato, Yasui Fumihiko, Hanawa Tomohide, Sugita Chise, Murakami Masanori, Yamada Tetsuya, Kohara Michinori, Wakai Sachiko. Reduced antibody response to SARS-CoV-2 in COVID-19 patients with newly diagnosed diabetes: a retrospective observational study BMC ENDOCRINE DISORDERS. 2023.01; 23 (1): 5. ( PubMed, DOI )

Yoshihiro Niitsu, Chikara Komiya, Akira Takeuchi, Kazunari Hara, Masato Horino, Jun Aoki, Rei Okazaki, Masanori Murakami, Kazutaka Tsujimoto, Kenji Ikeda, Tetsuya Yamada. Increased serum extracellular vesicle miR-144-3p and miR-486a-3p in a mouse model of adipose tissue regeneration promote hepatocyte proliferation by targeting Txnip. PLoS One. 2023; 18 (5): e0284989. ( PubMed, DOI )

Otsubo N, Fukuda T, Genhin C, Ishibashi F, Yamada T, Monzen K. Utility of Indices Obtained During Medical Checkups for Predicting Fatty Liver Disease in Non-obese People. Internal medicine (Tokyo, Japan). 2022.12; 62 (16): 2307-2319. ( PubMed, DOI )

Yujiro Nakano, Masanori Murakami, Kazunari Hara, Tatsuya Fukuda, Masato Horino, Akira Takeuchi, Yoshihiro Niitsu, Kumiko Shiba, Kazutaka Tsujimoto, Chikara Komiya, Minato Yokoyama, Kenji Ikeda, Takanobu Yoshimoto, Yasuhisa Fujii, Tetsuya Yamada. Long-term effects of primary aldosteronism treatment on patients with primary aldosteronism and chronic kidney disease. Clin Endocrinol (Oxf). 2022.11; 98 (3): 323-331. ( PubMed, DOI )

Ikeda Kenji, Yamada Tetsuya. カルシウム無益サイクリングによる脂肪組織熱産生(Adipose tissue thermogenesis by calcium futile cycling) The Journal of Biochemistry. 2022.10; 172 (4): 197-203. ( ichushi )

Nomura Motoko, Kurihara Isao, Itoh Hiroshi, Ichijo Takamasa, Katabami Takuyuki, Tsuiki Mika, Wada Norio, Yoneda Takashi, Sone Masakatsu, Oki Kenji, Yamada Tetsuya, Kobayashi Hiroki, Tamura Kouichi, Ogawa Yoshihiro, Inagaki Nobuya, Yamamoto Koichi, Otsuki Michio, Yabe Daisuke, Izawa Shoichiro, Takahashi Yutaka, Suzuki Tomoko, Yasoda Akihiro, Tanabe Akiyo, Naruse Mitsuhide, JPAS/JRAS Study Group. 原発性アルドステロン症患者における心血管疾患リスクとミネラルコルチコイド受容体拮抗薬によるレニン値の変化との関連(Association of cardiovascular disease risk and changes in renin levels by mineralocorticoid receptor antagonists in patients with primary aldosteronism) Hypertension Research. 2022.09; 45 (9): 1476-1485. ( ichushi )

Takahiro Fukaishi, Yuko Nakagawa, Ayako Fukunaka, Takashi Sato, Akemi Hara, Keiko Nakao, Michiko Saito, Kenji Kohno, Takeshi Miyatsuka, Motoyuki Tamaki, Munehide Matsuhisa, Taka-Aki Matsuoka, Tetsuya Yamada, Hirotaka Watada, Yoshio Fujitani. Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice. Diabetologia. 2021.12; 64 (12): 2803-2816. ( PubMed, DOI )

Saito K, Kurihara I, Itoh H, Ichijo T, Katabami T, Tsuiki M, Wada N, Yoneda T, Sone M, Oki K, Yamada T, Kobayashi H, Tamura K, Ogawa Y, Kawashima J, Inagaki N, Yamamoto K, Yamada M, Kamemura K, Fujii Y, Suzuki T, Yasoda A, Tanabe A, Naruse M, Japan Primary Aldosteronism Study/Japan Rare Intractable Adrenal Diseases Study Group.. Subtype-specific trends in the clinical picture of primary aldosteronism over a 13-year period. Journal of hypertension. 2021.11; 39 (11): 2325-2332. ( PubMed, DOI )

Yuko Adachi, Kazuki Ota, Isao Minami, Tetsuya Yamada, Takayuki Watanabe. Lower insulin secretion is associated with hippocampal and parahippocampal gyrus atrophy in elderly patients with type 2 diabetes mellitus. J Diabetes Investig. 2021.10; 12 (10): 1908-1913. ( PubMed, DOI )

Adachi Yuko, Ota Kazuki, Minami Isao, Yamada Tetsuya, Watanabe Takayuki. 高齢2型糖尿病患者においてインスリン分泌能低下は海馬および海馬傍回萎縮と関連する(Lower insulin secretion is associated with hippocampal and parahippocampal gyrus atrophy in elderly patients with type 2 diabetes mellitus) Journal of Diabetes Investigation. 2021.10; 12 (10): 1908-1913. ( ichushi )

Hiroko Beppu, Tatsuya Fukuda, Tomoko Kawanishi, Fumihiko Yasui, Minami Toda, Hitomi Kimura, Yuki Nakamura, Yuka Nakamura, Kaori Kojima, Hina Ogawa, Ayumi Ishiwatari, Yuiko Kamei, Toshie Ogawa, Yasutomo Abe, Mariko Endo, Tomohide Hanawa, Rie Mizobuchi, Chise Sugita, Koh Okamoto, Shuji Hatakeyama, Tetsusya Yamada, Michinori Kohara, Sachiko Wakai. Hemodialysis patients with coronavirus disease 2019: reduced antibody response. Clin Exp Nephrol. 2021.09; 26 (2): 170-177. ( PubMed, DOI )

Ryo Nakamaru, Koichi Yamamoto, Hiroshi Akasaka, Hiromi Rakugi, Isao Kurihara, Takashi Yoneda, Takamasa Ichijo, Takuyuki Katabami, Mika Tsuiki, Norio Wada, Tetsuya Yamada, Hiroki Kobayashi, Kouichi Tamura, Yoshihiro Ogawa, Junji Kawashima, Nobuya Inagaki, Megumi Fujita, Minemori Watanabe, Kohei Kamemura, Shintaro Okamura, Akiyo Tanabe, Mitsuhide Naruse, . Age-stratified comparison of clinical outcomes between medical and surgical treatments in patients with unilateral primary aldosteronism. Scientific Reports. 2021.05; 11 (1): 6925. ( PubMed, DOI )

Tatsuya Fukuda, Ryotaro Bouchi, Takato Takeuchi, Kikuko Amo-Shiinoki, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Kazuhiro Hirayama, Toshitaka Odamaki, Miki Igarashi, Ikuo Kimura, Katsuya Tanabe, Yukio Tanizawa, Tetsuya Yamada, Yoshihiro Ogawa. Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes. Diabetes Care. 2021.04; 44 (4): 1002-1011. ( PubMed, DOI )

Ryotaro Bouchi, Noriyuki Sonoda, Jun Itoh, Yasuhiro Ono, Tatsuya Fukuda, Takato Takeuchi, Junji Kishimoto, Tetsuya Yamada, Yoshihiro Ogawa. Effects of intensive exercise combined with dapagliflozin on body composition in patients with type 2 diabetes: a randomized controlled trial. Endocrine Journal. 2021.03; 68 (3): 329-343. ( PubMed, DOI )

Ryo Nakamaru, Koichi Yamamoto, Hiroshi Akasaka, Hiromi Rakugi, Isao Kurihara, Takashi Yoneda, Takamasa Ichijo, Takuyuki Katabami, Mika Tsuiki, Norio Wada, Tetsuya Yamada, Hiroki Kobayashi, Kouichi Tamura, Yoshihiro Ogawa, Junji Kawashima, Nobuya Inagaki, Megumi Fujita, Kenji Oki, Kohei Kamemura, Akiyo Tanabe, Mitsuhide Naruse, . Sex Differences in Renal Outcomes After Medical Treatment for Bilateral Primary Aldosteronism. Hypertension. 2021.02; 77 (2): 537-545. ( PubMed, DOI )

Kikuko Amo-Shiinoki, Katsuya Tanabe, Yoshinobu Hoshii, Hiroto Matsui, Risa Harano, Tatsuya Fukuda, Takato Takeuchi, Ryotaro Bouchi, Tokiyo Takagi, Masayuki Hatanaka, Komei Takeda, Shigeru Okuya, Wataru Nishimura, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Tetsuya Yamada, Yoshihiro Ogawa, Eiji Ikeda, Hiroaki Nagano, Yukio Tanizawa. Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes. JCI Insight. 2021.01; 6 (1): ( PubMed, DOI )

Kawahori K, Kondo Y, Yuan X, Kawasaki Y, Hanzawa N, Tsujimoto K, Wada F, Kohda T, Ishigami A, Yamada T, Ogawa Y, Hashimoto K. Ascorbic acid during the suckling period is required for proper DNA demethylation in the liver. Scientific reports. 2020.12; 10 (1): 21228. ( PubMed, DOI )

Nakano Yujiro, Komiya Chikara, Shimizu Hitomi, Mishima Hiroyuki, Shiba Kumiko, Tsujimoto Kazutaka, Ikeda Kenji, Kashimada Kenichi, Dateki Sumito, Yoshiura Koh-ichiro, Ogawa Yoshihiro, Yamada Tetsuya. ABCG5遺伝子に新規ヘテロ接合性バリアントを認めるエゼチミブ奏効の高コレステロール血症の1例(A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5) Endocrine Journal. 2020.11; 67 (11): 1099-1105. ( ichushi )

Kaneko Keizo, Sawada Shojiro, Satake Chihiro, Kondo Keiichi, Izumi Tomohito, Tanaka Mamiko, Imai Junta, Yamada Tetsuya, Katsushima Hiroki, Fujishima Fumiyoshi, Katagiri Hideki. Extraordinarily long-inactive solitary fibrous tumor transformed to produce big insulin-like growth factor-2, leading to hypoglycemia and rapid liposarcoma growth: a case report BMC Endocrine Disorders. 2020.09; 20 (1): 148. ( PubMed, DOI )

Kobayashi, Y; Haze, T; Yano, Y; Tamura, K; Kurihara, I; Ichijo, T; Yoneda, T; Katabami, T; Tsuiki, M; Wada, N; Ogawa, Y; Kawashima, J; Sone, M; Inagaki, N; Yamada, T; Okamoto, R; Fujita, M; Kamemura, K; Yamamoto, K; Izawa, S; Tanabe, A; Naruse, M. Associations Between Changes in Plasma Renin Activity and Aldosterone Concentrations and Changes in Kidney Function After Treatment for Primary Aldosteronism KIDNEY INTERNATIONAL REPORTS. 2020.08; 5 (8): 1291-1297. ( PubMed, DOI )

Nakano Y, Komiya C, Shimizu H, Mishima H, Shiba K, Tsujimoto K, Ikeda K, Kashimada K, Dateki S, Yoshiura KI, Ogawa Y, Yamada T. A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5. Endocrine Journal. 2020.07; 67 (11): 1099-1105. ( PubMed, DOI )

Ikeda K, Yamada T.. UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes Frontiers in Endocrinology. 2020.07; 11 498. ( PubMed, DOI )

Hosaka Shinichiro, Yamada Tetsuya, Takahashi Kei, Dan Takashi, Kaneko Keizo, Kodama Shinjiro, Asai Yoichiro, Munakata Yuichiro, Endo Akira, Sugawara Hiroto, Kawana Yohei, Yamamoto Junpei, Izumi Tomohito, Sawada Shojiro, Imai Junta, Miyata Toshio, Katagiri Hideki. Inhibition of Plasminogen Activator Inhibitor-1 Activation Suppresses High Fat Diet-Induced Weight GainviaAlleviation of Hypothalamic Leptin Resistance Frontiers in Pharmacology. 2020.06; 11 943. ( PubMed, DOI )

Ohno Y, Sone M, Inagaki N, Kawashima A, Takeda Y, Yoneda T, Kurihara I, Itoh H, Tsuiki M, Ichijo T, Katabami T, Wada N, Sakamoto R, Ogawa Y, Yoshimoto T, Yamada T, Kawashima J, Matsuda Y, Kobayashi H, Kamemura K, Yamamoto K, Otsuki M, Okamura S, Izawa S, Okamoto R, Tamura K, Tanabe A, Naruse M.. Nadir Aldosterone Levels After Confirmatory Tests Are Correlated With Left Ventricular Hypertrophy in Primary Aldosteronism. Hypertension. 2020.06; 75 (6): 1475-1482. ( PubMed, DOI )

Kobayashi Y, Haze T, Yano Y, Tamura K, Kurihara I, Ichijo T, Yoneda T, Katabami T, Tsuiki M, Wada N, Ogawa Y, Kawashima J, Sone M, Inagaki N, Yamada T, Okamoto R, Fujita M, Kamemura K, Yamamoto K, Izawa S, Tanabe A, Naruse M.. Associations Between Changes in Plasma Renin Activity and Aldosterone Concentrations and Changes in Kidney Function After Treatment for Primary Aldosteronism. Kidney International Reports. 2020.06; 5 (8): 1291-1297. ( DOI )

Nakamura Yuki, Yokoyama Minato, Yoshida Soichiro, Tanaka Hajime, Kijima Toshiki, Ishioka Junichiro, Matsuoka Yoh, Saito Kazutaka, Minami Isao, Yoshimoto Takanobu, Naito Shotaro, Ogawa Yoshihiro, Yamada Tetsuya, Uchida Shinichi, Fujii Yasuhisa. Postoperative renal impairment and longitudinal change in renal function after adrenalectomy in patients with Cushing's syndrome International Journal of Urology. 2020.05; 27 (5): 395-400. ( ichushi )

Nakamura Y, Yokoyama M, Yoshida S, Tanaka H, Kijima T, Ishioka J, Matsuoka Y, Saito K, Minami I, Yoshimoto T, Naito S, Ogawa Y, Yamada T, Uchida S, Fujii Y. Postoperative renal impairment and longitudinal change in renal function after adrenalectomy in patients with Cushing's syndrome. International journal of urology : official journal of the Japanese Urological Association. 2020.05; 27 (5): 395-400. ( PubMed, DOI )

Hayashi Ruriko, Minami Isao, Sasahara Yuriko, Izumiyama Hajime, Yoshimoto Takanobu, Kishino Mitsuhiro, Kudo Atsushi, Tateishi Ukihide, Tanabe Minoru, Yamada Tetsuya. Diagnostic accuracy of selective arterial calcium injection test for localization of gastrinoma Endocrine Journal. 2020.03; 67 (3): 305-315. ( ichushi )

Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y. Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing. Scientific reports. 2020.03; 10 (1): 5181. ( PubMed, DOI )

Kobayashi Hiroki, Nakamura Yoshihiro, Abe Masanori, Kurihara Isao, Itoh Hiroshi, Ichijo Takamasa, Takeda Yoshiyu, Yoneda Takashi, Katabami Takuyuki, Tsuiki Mika, Wada Norio, Ogawa Yoshihiro, Sakamoto Ryuichi, Kawashima Junji, Sone Masakatsu, Inagaki Nobuya, Yoshimoto Takanobu, Yamada Tetsuya, Okamoto Ryuji, Matsuda Yuichi, Fujita Megumi, Watanabe Minemori, Tamura Kouichi, Tanabe Akiyo, Naruse Mitsuhide. Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: analysis of surgical outcome European Journal of Endocrinology. 2020.03; 182 (3): 265-273. ( PubMed, DOI )

Fukaishi Takahiro, Minami Isao, Masuda Seizaburo, Miyachi Yasutaka, Tsujimoto Kazutaka, Izumiyama Hajime, Hashimoto Koshi, Yoshida Masayuki, Takahashi Sayako, Kashimada Kenichi, Morio Tomohiro, Kosaki Kenjiro, Maezawa Yoshiro, Yokote Koutaro, Yoshimoto Takanobu, Yamada Tetsuya. レプチン補充療法および代謝・内分泌プロファイルの短期・長期モニタリングを施行された全身性脂肪萎縮症関連早老症の1例(A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles) Endocrine Journal. 2020.02; 67 (2): 211-218. ( ichushi )

Fukuda T., Bouchi R., Asakawa M., Takeuchi T., Shiba K., Tsujimoto K., Komiya C., Yoshimoto T., Ogawa Y., Yamada T.. Sarcopenic obesity is associated with a faster decline in renal function in people with type 2 diabetes Diabetic Medicine. 2020.01; 37 (1): 105-113. ( PubMed, DOI )

Hayashi R, Minami I, Sasahara Y, Izumiyama H, Yoshimoto T, Kishino M, Kudo A, Tateishi U, Tanabe M, Yamada T. Diagnostic accuracy of selective arterial calcium injection test for localization of gastrinoma. Endocrine journal. 2019.12; ( PubMed, DOI )

Asakawa M, Itoh M, Suganami T, Sakai T, Kanai S, Shirakawa I, Yuan X, Hatayama T, Shimada S, Akiyama Y, Fujiu K, Inagaki Y, Manabe I, Yamaoka S, Yamada T, Tanaka S, Ogawa Y. Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis. Scientific reports. 2019.12; 9 (1): 19601. ( PubMed, DOI )

Fukaishi T, Minami I, Masuda S, Miyachi Y, Tsujimoto K, Izumiyama H, Hashimoto K, Yoshida M, Takahashi S, Kashimada K, Morio T, Kosaki K, Maezawa Y, Yokote K, Yoshimoto T, Yamada T. A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles. Endocrine journal. 2019.11; ( PubMed, DOI )

Nakano Yujiro, Yoshimoto Takanobu, Watanabe Ryo, Murakami Masanori, Fukuda Tatsuya, Saito Kazutaka, Fujii Yasuhisa, Akashi Takumi, Tanaka Toshihiro, Yamada Tetsuya, Naruse Mitsuhide, Ogawa Yoshihiro. miRNA299 involvement in CYP11B2 expression in aldosterone-producing adenoma EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2019.07; 181 (1): 69-78. ( PubMed, DOI )

Nakatsu Yusuke, Matsunaga Yasuka, Yamamotoya Takeshi, Ueda Koji, Inoue Masa-ki, Mizuno Yu, Nakanishi Mikako, Sano Tomomi, Yamawaki Yosuke, Kushiyama Akifumi, Sakoda Hideyuki, Fujishiro Midori, Ryo Akihide, Ono Hiraku, Minamino Tohru, Takahashi Shin-ichiro, Ohno Haruya, Yoneda Masayasu, Takahashi Kei, Ishihara Hisamitsu, Katagiri Hideki, Nishimura Fusanori, Kanematsu Takashi, Yamada Tetsuya, Asano Tomoichiro. Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16 CELL REPORTS. 2019.03; 26 (12): 3221-3230. ( PubMed, DOI )

Niitsu Y, Minami I, Izumiyama H, Hashimoto K, Yoshimoto T, Satou F, Tsujino M, Ota K, Kudo A, Tanabe M, Yamada T, Ogawa Y. Clinical outcomes of 20 Japanese patients with insulinoma treated with diazoxide. Endocrine journal. 2019.02; 66 (2): 149-155. ( PubMed, DOI )

Kaneko Keizo, Satake Chihiro, Izumi Tomohito, Tanaka Mamiko, Yamamoto Junpei, Asai Yoichiro, Sawada Shojiro, Imai Junta, Yamada Tetsuya, Katagiri Hideki. Enhancement of postprandial endogenous insulin secretion rather than exogenous insulin injection ameliorated insulin antibody-induced unstable diabetes: a case report BMC ENDOCRINE DISORDERS. 2019.01; 19 (1): 5. ( PubMed, DOI )

Nakano Y, Hashimoto K, Ohkiba N, Okuma H, Minami I, Takahashi H, Tanaka Y, Yoshimoto T, Yamada T. A Case of Refractory Hypothyroidism due to Poor Compliance Treated with the Weekly Intravenous and Oral Levothyroxine Administration. Case reports in endocrinology. 2019; 2019 5986014. ( PubMed, DOI )

Izumi Tomohito, Imai Junta, Yamamoto Junpei, Kawana Yohei, Endo Akira, Sugawara Hiroto, Kohata Masato, Asai Yoichiro, Takahashi Kei, Kodama Shinjiro, Kaneko Keizo, Gao Junhong, Uno Kenji, Sawada Shojiro, Kalinichenko Vladimir V., Ishigaki Yasushi, Yamada Tetsuya, Katagiri Hideki. Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation NATURE COMMUNICATIONS. 2018.12; 9 (1): 5300. ( PubMed, DOI )

Yuki Yasumoto, Hirofumi Miyazaki, Masaki Ogata, Yoshiteru Kagawa, Yui Yamamoto, Ariful Islam, Tetsuya Yamada, Hideki Katagiri, Yuji Owada. Glial Fatty Acid-Binding Protein 7 (FABP7) Regulates Neuronal Leptin Sensitivity in the Hypothalamic Arcuate Nucleus. Mol. Neurobiol.. 2018.12; 55 (12): 9016-9028. ( PubMed, DOI )

Inamori KI, Ito H, Tamura Y, Nitta T, Yang X, Nihei W, Shishido F, Imazu S, Tsukita S, Yamada T, Katagiri H, Inokuchi JI. Deficient ganglioside synthesis restores responsiveness to leptin and melanocortin signaling in obese KKAy mice. Journal of lipid research. 2018.08; 59 (8): 1472-1481. ( PubMed, DOI )

Honma M, Sawada S, Ueno Y, Murakami K, Yamada T, Gao J, Kodama S, Izumi T, Takahashi K, Tsukita S, Uno K, Imai J, Kakazu E, Kondo Y, Mizuno K, Kawagishi N, Shimosegawa T, Katagiri H. Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers. International journal of obesity (2005). 2018.05; ( PubMed, DOI )

Kaneko R, Sawada S, Tokita A, Honkura R, Tamura N, Kodama S, Izumi T, Takahashi K, Uno K, Imai J, Yamada T, Miyachi Y, Hasegawa H, Kanai H, Ishigaki Y, Katagiri H. Serum cystatin C level is associated with carotid arterial wall elasticity in subjects with type 2 diabetes mellitus: A potential marker of early-stage atherosclerosis. Diabetes research and clinical practice. 2018.05; 139 43-51. ( PubMed, DOI )

Yasumoto Y, Miyazaki H, Ogata M, Kagawa Y, Yamamoto Y, Islam A, Yamada T, Katagiri H, Owada Y.. Glial Fatty Acid-Binding Protein 7 (FABP7) Regulates Neuronal Leptin Sensitivity in the Hypothalamic Arcuate Nucleus. Mol Neurobiol. . 2018.04; ( DOI )

Munakata Yuichiro, Yamada Tetsuya, Imai Junta, Takahashi Kei, Tsukita Sohei, Shirai Yuta, Kodama Shinjiro, Asai Yoichiro, Sugisawa Takashi, Chiba Yumiko, Kaneko Keizo, Uno Kenji, Sawada Shojiro, Hatakeyama Hiroyasu, Kanzaki Makoto, Miyazaki Jun-ichi, Oka Yoshitomo, Katagiri Hideki. Olfactory receptors are expressed in pancreatic beta-cells and promote glucose-stimulated insulin secretion SCIENTIFIC REPORTS. 2018.01; 8 (1): 1499. ( PubMed, DOI )

Yamamoto Junpei, Imai Junta, Izumi Tomohito, Takahashi Hironori, Kawana Yohei, Takahashi Kei, Kodama Shinjiro, Kaneko Keizo, Gao Junhong, Uno Kenji, Sawada Shojiro, Asano Tomoichiro, Kalinichenko Vladimir V., Susaki Etsuo A., Kanzaki Makoto, Ueda Hiroki R., Ishigaki Yasushi, Yamada Tetsuya, Katagiri Hideki. Neuronal signals regulate obesity induced beta-cell proliferation by FoxM1 dependent mechanism NATURE COMMUNICATIONS. 2017.12; 8 (1): 1930. ( PubMed, DOI )

Gota Sakai, Ikuo Inoue, Tokuko Suzuki, Takashi Sumita, Kouichi Inukai, Shigehiro Katayama, Takuya Awata, Tetsuya Yamada, Tomoichiro Asano, Hideki Katagiri, Mitsuhiko Noda, Akira Shimada, Hiraku Ono. Effects of the Activation of Three Major Hepatic Akt Substrates on Glucose Metabolism in Male Mice. Endocrinology. 2017.08; 158 (8): 2659-2671. ( PubMed, DOI )

Yamada Daisuke, Koppensteiner Peter, Odagiri Saori, Eguchi Megumi, Yamaguchi Shun, Yamada Tetsuya, Katagiri Hideki, Wada Keiji, Sekiguchi Masayuki. Common Hepatic Branch of Vagus Nerve-Dependent Expression of Immediate Early Genes in the Mouse Brain by Intraportal L-Arginine: Comparison with Cholecystokinin-8 FRONTIERS IN NEUROSCIENCE. 2017.06; 11 366. ( PubMed, DOI )

Asai Yoichiro, Yamada Tetsuya, Tsukita Sohei, Takahashi Kei, Maekawa Masamitsu, Honma Midori, Ikeda Masanori, Murakami Keigo, Munakata Yuichiro, Shirai Yuta, Kodama Shinjiro, Sugisawa Takashi, Chiba Yumiko, Kondo Yasuteru, Kaneko Keizo, Uno Kenji, Sawada Shojiro, Imai Junta, Nakamura Yasuhiro, Yamaguchi Hiroaki, Tanaka Kozo, Sasano Hironobu, Mano Nariyasu, Ueno Yoshiyuki, Shimosegawa Tooru, Katagiri Hideki. Activation of the Hypoxia Inducible Factor 1 alpha Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones GASTROENTEROLOGY. 2017.05; 152 (6): 1521-+. ( PubMed, DOI )

Horiuchi Takahiro, Sakata Natsumi, Narumi Yoshihiro, Kimura Tomohiro, Hayashi Takashi, Nagano Keisuke, Liu Keyue, Nishibori Masahiro, Tsukita Sohei, Yamada Tetsuya, Katagiri Hideki, Shirakawa Ryutaro, Horiuchi Hisanori. Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity JOURNAL OF BIOLOGICAL CHEMISTRY. 2017.05; 292 (20): 8436-8446. ( PubMed, DOI )

Kaneko Keizo, Satake Chihiro, Yamamoto Junpei, Takahashi Hironori, Sawada Shojiro, Imai Junta, Yamada Tetsuya, Katagiri Hideki. 劇症1型糖尿病と診断されながら内因性インスリン分泌の回復が得られた特発性1型糖尿病の1例(A case of idiopathic type 1 diabetes with subsequent recovery of endogenous insulin secretion despite initial diagnosis of fulminant type 1 diabetes) Endocrine Journal. 2017.03; 64 (3): 369-374. ( ichushi )

Kawana Yohei, Imai Junta, Sawada Shojiro, Yamada Tetsuya, Katagiri Hideki. Sodium-Glucose Cotransporter 2 Inhibitor Improves Complications of Lipodystrophy: A Case Report ANNALS OF INTERNAL MEDICINE. 2017.03; 166 (6): 450-451. ( PubMed, DOI )

Kaneko K, Satake C, Yamamoto J, Takahashi H, Sawada S, Imai J, Yamada T, Katagiri H. A case of idiopathic type 1 diabetes with subsequent recovery of endogenous insulin secretion despite initial diagnosis of fulminant type 1 diabetes. Endocrine journal. 2017.03; 64 (3): 369-374. ( PubMed, DOI )

Takeda E, Suzuki Y, Yamada T, Katagiri H, Sato Y.. Knockout of Vasohibin-1 Gene in Mice Results in Healthy Longevity with Reduced Expression of Insulin Receptor, Insulin Receptor Substrate 1, and Insulin Receptor Substrate 2 in Their White Adipose Tissue. J Aging Res.. 2017.03; 2017:9851380. ( DOI )

Suzuki Toru, Gao Junhong, Ishigaki Yasushi, Kondo Keiichi, Sawada Shojiro, Izumi Tomohito, Uno Kenji, Kaneko Keizo, Tsukita Sohei, Takahashi Kei, Asao Atsuko, Ishii Naoto, Imai Junta, Yamada Tetsuya, Oyadomari Seiichi, Katagiri Hideki. ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity CELL REPORTS. 2017.02; 18 (8): 2045-2057. ( PubMed, DOI )

Tsukita Sohei, Yamada Tetsuya, Takahashi Kei, Munakata Yuichiro, Hosaka Shinichiro, Takahashi Hironobu, Gao Junhong, Shirai Yuta, Kodama Shinjiro, Asai Yoichiro, Sugisawa Takashi, Chiba Yumiko, Kaneko Keizo, Uno Kenji, Sawada Shojiro, Imai Junta, Katagiri Hideki. MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic beta-Cell Proliferation EBIOMEDICINE. 2017.02; 15 163-172. ( PubMed, DOI )

Eichi Takeda, Yasuhiro Suzuki, Tetsuya Yamada, Hideki Katagiri, Yasufumi Sato. Knockout of Vasohibin-1 Gene in Mice Results in Healthy Longevity with Reduced Expression of Insulin Receptor, Insulin Receptor Substrate 1, and Insulin Receptor Substrate 2 in Their White Adipose Tissue. J Aging Res. 2017; 2017 9851380. ( PubMed, DOI )

Nobuyuki Sakayori, Takako Kikkawa, Hisanori Tokuda, Emiko Kiryu, Kaichi Yoshizaki, Hiroshi Kawashima, Tetsuya Yamada, Hiroyuki Arai, Jing X Kang, Hideki Katagiri, Hiroshi Shibata, Sheila M Innis, Makoto Arita, Noriko Osumi. Maternal dietary imbalance between omega-6 and omega-3 polyunsaturated fatty acids impairs neocortical development via epoxy metabolites. Stem Cells. 2016.02; 34 (2): 470-482. ( PubMed, DOI )

Toru Suzuki, Shojiro Sawada, Yasushi Ishigaki, Sohei Tsukita, Shinjiro Kodama, Takashi Sugisawa, Junta Imai, Tetsuya Yamada, Takashi Yamaguchi, Takeyoshi Murano, Hideki Katagiri. Lipoprotein Lipase Deficiency (R243H) in a Type 2 Diabetes Patient with Multiple Arterial Aneurysms. Intern. Med.. 2016; 55 (9): 1131-1136. ( PubMed, DOI )

Yumiko Chiba, Tetsuya Yamada, Sohei Tsukita, Kei Takahashi, Yuichiro Munakata, Yuta Shirai, Shinjiro Kodama, Yoichiro Asai, Takashi Sugisawa, Kenji Uno, Shojiro Sawada, Junta Imai, Kazuhiro Nakamura, Hideki Katagiri. Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, Acutely Reduces Energy Expenditure in BAT via Neural Signals in Mice. PLoS ONE. 2016; 11 (3): e0150756. ( PubMed, DOI )

Mamiko Tanaka, Junta Imai, Michihiro Satoh, Takanao Hashimoto, Tomohito Izumi, Shojiro Sawada, Kenji Uno, Yutaka Hasegawa, Keizo Kaneko, Tetsuya Yamada, Yasushi Ishigaki, Yutaka Imai, Hideki Katagiri. Impacts of the Great East Japan Earthquake on diabetic patients. J Diabetes Investig. 2015.09; 6 (5): 577-586. ( PubMed, DOI )

Kenji Uno, Tetsuya Yamada, Yasushi Ishigaki, Junta Imai, Yutaka Hasegawa, Shojiro Sawada, Keizo Kaneko, Hiraku Ono, Tomoichiro Asano, Yoshitomo Oka, Hideki Katagiri. A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals. Nat Commun. 2015.08; 6 7940. ( PubMed, DOI )

Mamiko Tanaka, Junta Imai, Michihiro Satoh, Takanao Hashimoto, Tomohito Izumi, Shojiro Sawada, Kenji Uno, Yutaka Hasegawa, Keizo Kaneko, Tetsuya Yamada, Yasushi Ishigaki, Yutaka Imai, Hideki Katagiri. Glycemic control in diabetic patients with impaired endogenous insulin secretory capacity is vulnerable after a natural disaster: study of Great East Japan Earthquake. Diabetes Care. 2014.10; 37 (10): e212-e213. ( PubMed, DOI )

Shinjiro Kodama, Tetsuya Yamada, Junta Imai, Shojiro Sawada, Kei Takahashi, Sohei Tsukita, Keizo Kaneko, Kenji Uno, Yasushi Ishigaki, Yoshitomo Oka, Hideki Katagiri. Simultaneous copy number losses within multiple subtelomeric regions in early-onset type 2 diabetes mellitus. PLoS ONE. 2014; 9 (4): e88602. ( PubMed, DOI )

Kazuki Noda, Sota Nakajima, Shigeo Godo, Hiroki Saito, Shohei Ikeda, Toru Shimizu, Budbazar Enkhjargal, Yoshihiro Fukumoto, Sohei Tsukita, Tetsuya Yamada, Hideki Katagiri, Hiroaki Shimokawa. Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice. PLoS ONE. 2014; 9 (11): e110446. ( PubMed, DOI )

Tetsuya Yamada, Sohei Tsukita, Hideki Katagiri. Identification of a novel interorgan mechanism favoring energy storage in overnutrition. Adipocyte. 2013.10; 2 (4): 281-284. ( PubMed, DOI )

Keiichi Kondo, Yasushi Ishigaki, Junhong Gao, Tetsuya Yamada, Junta Imai, Shojiro Sawada, Akihiko Muto, Yoshitomo Oka, Kazuhiko Igarashi, Hideki Katagiri. Bach1 deficiency protects pancreatic β-cells from oxidative stress injury. Am. J. Physiol. Endocrinol. Metab.. 2013.09; 305 (5): E641-E648. ( PubMed, DOI )

Masahito Takagi, Yasushi Ishigaki, Kenji Uno, Shojiro Sawada, Junta Imai, Keizo Kaneko, Yutaka Hasegawa, Tetsuya Yamada, Ai Tokita, Kazumi Iseki, Shigenori Kanno, Yoshiyuki Nishio, Hideki Katagiri, Etsuro Mori. Cognitive dysfunction associated with anti-glutamic acid decarboxylase autoimmunity: a case-control study. BMC Neurol. 2013.07; 13 76. ( PubMed, DOI )

Kei Takahashi, Tetsuya Yamada, Sohei Tsukita, Keizo Kaneko, Yuta Shirai, Yuichiro Munakata, Yasushi Ishigaki, Junta Imai, Kenji Uno, Yutaka Hasegawa, Shojiro Sawada, Yoshitomo Oka, Hideki Katagiri. Chronic mild stress alters circadian expressions of molecular clock genes in the liver. Am. J. Physiol. Endocrinol. Metab.. 2013.02; 304 (3): E301-E309. ( PubMed, DOI )

Tokuo Saito, Yutaka Hasegawa, Yasushi Ishigaki, Tetsuya Yamada, Junhong Gao, Junta Imai, Kenji Uno, Keizo Kaneko, Takehide Ogihara, Tatsuo Shimosawa, Tomoichiro Asano, Toshiro Fujita, Yoshitomo Oka, Hideki Katagiri. Importance of endothelial NF-κB signalling in vascular remodelling and aortic aneurysm formation. Cardiovasc. Res.. 2013.01; 97 (1): 106-114. ( PubMed, DOI )

Yoshihiko Izumida, Naoya Yahagi, Yoshinori Takeuchi, Makiko Nishi, Akito Shikama, Ayako Takarada, Yukari Masuda, Midori Kubota, Takashi Matsuzaka, Yoshimi Nakagawa, Yoko Iizuka, Keiji Itaka, Kazunori Kataoka, Seiji Shioda, Akira Niijima, Tetsuya Yamada, Hideki Katagiri, Ryozo Nagai, Nobuhiro Yamada, Takashi Kadowaki, Hitoshi Shimano. Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization. Nat Commun. 2013; 4 2316. ( PubMed, DOI )

Sohei Tsukita, Tetsuya Yamada, Kenji Uno, Kei Takahashi, Keizo Kaneko, Yasushi Ishigaki, Junta Imai, Yutaka Hasegawa, Shojiro Sawada, Hisamitsu Ishihara, Yoshitomo Oka, Hideki Katagiri. Hepatic glucokinase modulates obesity predisposition by regulating BAT thermogenesis via neural signals. Cell Metab.. 2012.12; 16 (6): 825-832. ( PubMed, DOI )

Kenji Uno, Tetsuya Yamada, Yasushi Ishigaki, Junta Imai, Yutaka Hasegawa, Junhong Gao, Keizo Kaneko, Kimihiko Matsusue, Tomomi Yamazaki, Yoshitomo Oka, Hideki Katagiri. Hepatic peroxisome proliferator-activated receptor-γ-fat-specific protein 27 pathway contributes to obesity-related hypertension via afferent vagal signals. Eur. Heart J.. 2012.05; 33 (10): 1279-1289. ( PubMed, DOI )

Yutaka Hasegawa, Tokuo Saito, Takehide Ogihara, Yasushi Ishigaki, Tetsuya Yamada, Junta Imai, Kenji Uno, Junhong Gao, Keizo Kaneko, Tatsuo Shimosawa, Tomoichiro Asano, Toshiro Fujita, Yoshitomo Oka, Hideki Katagiri. Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs life spans. Circulation. 2012.03; 125 (9): 1122-1133. ( PubMed, DOI )

Yuichiro Munakata, Tetsuya Yamada, Kazuma Takahashi, Sohei Tsukita, Kei Takahashi, Shojiro Sawada, Junta Imai, Yasushi Ishigaki, Yoshitomo Oka, Hideki Katagiri. A case of slowly progressive type 1 diabetes with insulin independence maintained for 10 years with α-glucosidase inhibitor monotherapy. Intern. Med.. 2012; 51 (24): 3391-3394. ( PubMed )

Junhong Gao, Yasushi Ishigaki, Tetsuya Yamada, Keiichi Kondo, Suguru Yamaguchi, Junta Imai, Kenji Uno, Yutaka Hasegawa, Shojiro Sawada, Hisamitsu Ishihara, Seiichi Oyadomari, Masataka Mori, Yoshitomo Oka, Hideki Katagiri. Involvement of endoplasmic stress protein C/EBP homologous protein in arteriosclerosis acceleration with augmented biological stress responses. Circulation. 2011.08; 124 (7): 830-839. ( PubMed, DOI )

Toshinobu Suzuki, Junta Imai, Tetsuya Yamada, Yasushi Ishigaki, Keizo Kaneko, Kenji Uno, Yutaka Hasegawa, Hisamitsu Ishihara, Yoshitomo Oka, Hideki Katagiri. Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway. Diabetes. 2011.02; 60 (2): 537-547. ( PubMed, DOI )

Satoshi Sugita, Yasutomi Kamei, Fumiko Akaike, Takayoshi Suganami, Sayaka Kanai, Maki Hattori, Yasuko Manabe, Nobuharu Fujii, Takako Takai-Igarashi, Miki Tadaishi, Jun-ichiro Oka, Hiroyuki Aburatani, Tetsuya Yamada, Hideki Katagiri, Saori Kakehi, Yoshifumi Tamura, Hideo Kubo, Kenichi Nishida, Shinji Miura, Osamu Ezaki, Yoshihiro Ogawa. Increased systemic glucose tolerance with increased muscle glucose uptake in transgenic mice overexpressing RXRγ in skeletal muscle. PLoS ONE. 2011; 6 (5): e20467. ( PubMed, DOI )

Hirohito Kudo, Mitsuru Emi, Yasushi Ishigaki, Uiko Tsunoda, Yoshinori Hinokio, Miho Ishii, Hidenori Sato, Tetsuya Yamada, Hideki Katagiri, Yoshitomo Oka. Frequent loss of genome gap region in 4p16.3 subtelomere in early-onset type 2 diabetes mellitus. Exp Diabetes Res. 2011; 2011 498460. ( PubMed, DOI )

Etsuo Susaki, Chie Kaneko-Oshikawa, Keishi Miyata, Mitsuhisa Tabata, Tetsuya Yamada, Yuichi Oike, Hideki Katagiri, Keiichi I Nakayama. Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity. J. Biol. Chem.. 2010.05; 285 (20): 15538-15547. ( PubMed, DOI )

Chen Chen, Kazuma Takahashi, Ayumi Yoshida, Yumiko Takizawa, Yan Lee, Masaki Nakui, Hideyuki Doi, Yuji Takebayashi, Manabu Fukumoto, Testuya Yamada, Hideki Katagiri, Yoshitomo Oka, Jo Satoh. Characterization of a novel murine preadipocyte line, AP-18, isolated from subcutaneous tissue: analysis of adipocyte-related gene expressions. Cell Biol. Int.. 2010.02; 34 (3): 293-299. ( PubMed, DOI )

Mitsuhisa Tabata, Tsuyoshi Kadomatsu, Shigetomo Fukuhara, Keishi Miyata, Yasuhiro Ito, Motoyoshi Endo, Takashi Urano, Hui Juan Zhu, Hiroto Tsukano, Hirokazu Tazume, Koichi Kaikita, Kazuya Miyashita, Takao Iwawaki, Michio Shimabukuro, Kazuhiko Sakaguchi, Takaaki Ito, Naomi Nakagata, Tetsuya Yamada, Hideki Katagiri, Masato Kasuga, Yukio Ando, Hisao Ogawa, Naoki Mochizuki, Hiroshi Itoh, Toshio Suda, Yuichi Oike. Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab.. 2009.09; 10 (3): 178-188. ( PubMed, DOI )

Junta Imai, Tetsuya Yamada, Tokuo Saito, Yasushi Ishigaki, Yoshinori Hinokio, Hidetoshi Kotake, Yoshitomo Oka, Hideki Katagiri. Eradication of insulin resistance. Lancet. 2009.07; 374 (9685): 264. ( PubMed, DOI )

Keizo Kaneko, Tetsuya Yamada, Sohei Tsukita, Kei Takahashi, Yasushi Ishigaki, Yoshitomo Oka, Hideki Katagiri. Obesity alters circadian expressions of molecular clock genes in the brainstem. Brain Res.. 2009.03; 1263 58-68. ( PubMed, DOI )

Takehide Ogihara, Hideki Katagiri, Tetsuya Yamada, Hirohito Kudo, Junta Imai, Yasushi Ishigaki, Yoshinori Hinokio, Yoko Yamagiwa, Yoshiyuki Ueno, Tooru Shimosegawa, Yoshitomo Oka. Peginterferon (PEG-IFN) plus ribavirin combination therapy, but neither interferon nor PGE-IFN alone, induced type 1 diabetes in a patient with chronic hepatitis C. Intern. Med.. 2009; 48 (16): 1387-1390. ( PubMed )

Junta Imai, Hideki Katagiri, Tetsuya Yamada, Yasushi Ishigaki, Toshinobu Suzuki, Hirohito Kudo, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Keizo Kaneko, Hisamitsu Ishihara, Akira Niijima, Masamitsu Nakazato, Tomoichiro Asano, Yasuhiko Minokoshi, Yoshitomo Oka. Regulation of pancreatic beta cell mass by neuronal signals from the liver. Science. 2008.11; 322 (5905): 1250-1254. ( PubMed, DOI )

Yasushi Ishigaki, Hideki Katagiri, Junhong Gao, Tetsuya Yamada, Junta Imai, Kenji Uno, Yutaka Hasegawa, Keizo Kaneko, Takehide Ogihara, Hisamitsu Ishihara, Yuko Sato, Kenji Takikawa, Norihisa Nishimichi, Haruo Matsuda, Tatsuya Sawamura, Yoshitomo Oka. Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis. Circulation. 2008.07; 118 (1): 75-83. ( PubMed, DOI )

Tetsuya Yamada, Yoshitomo Oka, Hideki Katagiri. Inter-organ metabolic communication involved in energy homeostasis: potential therapeutic targets for obesity and metabolic syndrome. Pharmacol. Ther.. 2008.01; 117 (1): 188-198. ( PubMed, DOI )

Tetsuya Yamada, Junta Imai, Yasushi Ishigaki, Yoshinori Hinokio, Yoshitomo Oka, Hideki Katagiri. Possible relevance of HLA-DRB1*0403 haplotype in insulin autoimmune syndrome induced by alpha-lipoic acid, used as a dietary supplement. Diabetes Care. 2007.12; 30 (12): e131. ( PubMed, DOI )

Tetsuya Yamada, Hideki Katagiri. Avenues of communication between the brain and tissues/organs involved in energy homeostasis. Endocr. J.. 2007.08; 54 (4): 497-505. ( PubMed )

Hideki Katagiri, Tetsuya Yamada, Yoshitomo Oka. Adiposity and cardiovascular disorders: disturbance of the regulatory system consisting of humoral and neuronal signals. Circ. Res.. 2007.07; 101 (1): 27-39. ( PubMed, DOI )

Yutaka Hasegawa, Takehide Ogihara, Tetsuya Yamada, Yasushi Ishigaki, Junta Imai, Kenji Uno, Junhong Gao, Keizo Kaneko, Hisamitsu Ishihara, Hironobu Sasano, Hiromitsu Nakauchi, Yoshitomo Oka, Hideki Katagiri. Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization. Endocrinology. 2007.05; 148 (5): 2006-2015. ( PubMed, DOI )

Junhong Gao, Hideki Katagiri, Yasushi Ishigaki, Tetsuya Yamada, Takehide Ogihara, Junta Imai, Kenji Uno, Yutaka Hasegawa, Makoto Kanzaki, Tokuo T Yamamoto, Shun Ishibashi, Yoshitomo Oka. Involvement of apolipoprotein E in excess fat accumulation and insulin resistance. Diabetes. 2007.01; 56 (1): 24-33. ( PubMed, DOI )

Junta Imai, Hideki Katagiri, Tetsuya Yamada, Yasushi Ishigaki, Takehide Ogihara, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Hisamitsu Ishihara, Hironobu Sasano, Yoshitomo Oka. Cold exposure suppresses serum adiponectin levels through sympathetic nerve activation in mice. Obesity (Silver Spring). 2006.07; 14 (7): 1132-1141. ( PubMed, DOI )

Kenji Uno, Hideki Katagiri, Tetsuya Yamada, Yasushi Ishigaki, Takehide Ogihara, Junta Imai, Yutaka Hasegawa, Junhong Gao, Keizo Kaneko, Hiroko Iwasaki, Hisamitsu Ishihara, Hironobu Sasano, Kouichi Inukai, Hiroyuki Mizuguchi, Tomoichiro Asano, Masakazu Shiota, Masamitsu Nakazato, Yoshitomo Oka. Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity. Science. 2006.06; 312 (5780): 1656-1659. ( PubMed, DOI )

Tetsuya Yamada, Hideki Katagiri, Yasushi Ishigaki, Takehide Ogihara, Junta Imai, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Hisamitsu Ishihara, Akira Niijima, Hiroyuki Mano, Hiroyuki Aburatani, Tomoichiro Asano, Yoshitomo Oka. Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: neuronal involvement in food-intake regulation. Cell Metab.. 2006.03; 3 (3): 223-229. ( PubMed, DOI )

Yasushi Ishigaki, Hideki Katagiri, Tetsuya Yamada, Takehide Ogihara, Junta Imai, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Hisamitsu Ishihara, Tooru Shimosegawa, Hideyuki Sakoda, Tomoichiro Asano, Yoshitomo Oka. Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity. Diabetes. 2005.02; 54 (2): 322-332. ( PubMed )

Junta Imai, Hideki Katagiri, Tetsuya Yamada, Yasushi Ishigaki, Takehide Ogihara, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Hisamitsu Ishihara, Hironobu Sasano, Hiroyuki Mizuguchi, Tomoichiro Asano, Yoshitomo Oka. Constitutively active PDX1 induced efficient insulin production in adult murine liver. Biochem. Biophys. Res. Commun.. 2005.01; 326 (2): 402-409. ( PubMed, DOI )

Masatoshi Tsuru, Hideki Katagiri, Tomoichiro Asano, Tetsuya Yamada, Shigeo Ohno, Takehide Ogihara, Yoshitomo Oka. Role of PKC isoforms in glucose transport in 3T3-L1 adipocytes: insignificance of atypical PKC. Am. J. Physiol. Endocrinol. Metab.. 2002.08; 283 (2): E338-E345. ( PubMed, DOI )

Tetsuya Yamada, Hideki Katagiri, Tomoichiro Asano, Masatoshi Tsuru, Kouichi Inukai, Hiraku Ono, Tatsuhiko Kodama, Masatoshi Kikuchi, Yoshitomo Oka. Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes. Am. J. Physiol. Endocrinol. Metab.. 2002.06; 282 (6): E1385-E1394. ( PubMed, DOI )

Hideki Katagiri, Tomoichiro Asano, Tetsuya Yamada, Toshifumi Aoyama, Yasushi Fukushima, Masatoshi Kikuchi, Tatsuhiko Kodama, Yoshitomo Oka. Acyl-coenzyme A dehydrogenases are localized on GLUT4-containing vesicles via association with insulin-regulated aminopeptidase in a manner dependent on its dileucine motif. Mol. Endocrinol.. 2002.05; 16 (5): 1049-1059. ( PubMed, DOI )

T Yamada, H Katagiri, T Asano, K Inukai, M Tsuru, T Kodama, M Kikuchi, Y Oka. 3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells. J. Biol. Chem.. 2001.02; 276 (7): 5339-5345. ( PubMed, DOI )

K Katsuki, K Shinohara, K Takeda, K Ariyoshi, T Yamada, N Kameda, T Takahashi, R Nawata, S Shibata, Y Asano, S Okamura. Chronic neutrophilic leukemia with acute myeloblastic transformation. Jpn. J. Clin. Oncol.. 2000.08; 30 (8): 362-365. ( PubMed )

R Nawata, K Shinohara, T Yamada, T Takahashi, K Katsuki, K Takeda, N Kameda, K Ariyoshi, I Ota, K Muraki. Morphological and cytogenetic changes in therapy-related leukemia developed in a t(8;21)-acute myeloid leukemia (M2) patient: sequential cytogenetic and molecular analyses. Int. J. Hematol.. 2000.06; 71 (4): 353-358. ( PubMed )

T Yamada, K Shinohara, K Takeda, N Kameda, K Katsuki, K Ariyoshi, T Kamei. Second lung adenocarcinoma after combination chemotherapy in two patients with primary non-Hodgkin's lymphoma. Jpn. J. Clin. Oncol.. 1999.04; 29 (4): 226-228. ( PubMed )

K Katsuki, K Shinohara, N Kameda, T Yamada, K Takeda, T Kamei. Two cases of myelodysplastic syndrome with extramedullary polyclonal plasma cell proliferation and autoantibody production: possible role of soluble Fas antigen for production of excessive self-reactive B cells. Intern. Med.. 1998.11; 37 (11): 973-977. ( PubMed )

T Yamada, K Shinohara, K Katsuki. A case of idiopathic hypereosinophilic syndrome complicated with disseminated intravascular coagulation. Am. J. Hematol.. 1998.09; 59 (1): 100-101. ( PubMed )

M Nishimura, T Yamada, T Andoh, T Tao, M Emoto, T Ohji, K Matsuda, N Kameda, Y Satoh, A Matsutani, Y Azuno, Y Oka. Granulocyte colony-stimulating factor (G-CSF) dependent hematopoiesis with monosomy 7 in a patient with severe aplastic anemia after ATG/CsA/G-CSF combined therapy. Int. J. Hematol.. 1998.08; 68 (2): 203-211. ( PubMed )

K Katsuki, K Shinohara, T Yamada. A case of fatal seizure and unconsciousness caused by panipenem/betamipron. Kansenshogaku Zasshi. 1998.06; 72 (6): 651-653. ( PubMed )

T Yamada, K Shinohara, K Katsuki. Severe Thrombocytopenia Caused by Simvastatin in which Thrombocyte Recovery was Initiated after Severe Bacterial Infection. Clin Drug Investig. 1998; 16 (2): 172-174. ( PubMed, DOI )

Yamada Tetsuya, Katagiri Hideki. 全身性エネルギー代謝における肝臓からの臓器間神経ネットワークの役割(Role of the inter-organ neural network from the liver in systemic energy metabolism). Experimental Animals 2018.07.01

Yamada Tetsuya, Katagiri Hideki. 全身性エネルギー代謝における肝臓からの臓器間神経ネットワークの役割(Role of the inter-organ neural network from the liver in systemic energy metabolism). Experimental Animals 2018.07.01

Yamada Tetsuya, Katagiri Hideki. 全身性エネルギー代謝における肝臓からの臓器間神経ネットワークの役割(Role of the inter-organ neural network from the liver in systemic energy metabolism). Experimental Animals 2018.07.01

Yamada Tetsuya, Katagiri Hideki. 全身性エネルギー代謝における肝臓からの臓器間神経ネットワークの役割(Role of the inter-organ neural network from the liver in systemic energy metabolism). Experimental Animals 2018.07.01

Yamada Tetsuya, Katagiri Hideki. 全身性エネルギー代謝における肝臓からの臓器間神経ネットワークの役割(Role of the inter-organ neural network from the liver in systemic energy metabolism). Experimental Animals 2018.07.01

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート(Recent progress of research toward pancreatic islet regeneration MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 第61回日本糖尿病学会年次学術集会 2018.05.24

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート　インスリン欠乏性糖尿病マウスモデルにおいてmicroRNAは膵β細胞増殖を介して高血糖を改善する(Recent progress of research toward pancreatic islet regeneration　MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 糖尿病 2018.04.01

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート　インスリン欠乏性糖尿病マウスモデルにおいてmicroRNAは膵β細胞増殖を介して高血糖を改善する(Recent progress of research toward pancreatic islet regeneration　MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 糖尿病 2018.04.01

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート　インスリン欠乏性糖尿病マウスモデルにおいてmicroRNAは膵β細胞増殖を介して高血糖を改善する(Recent progress of research toward pancreatic islet regeneration　MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 糖尿病 2018.04.01

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート　インスリン欠乏性糖尿病マウスモデルにおいてmicroRNAは膵β細胞増殖を介して高血糖を改善する(Recent progress of research toward pancreatic islet regeneration　MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 糖尿病 2018.04.01

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート　インスリン欠乏性糖尿病マウスモデルにおいてmicroRNAは膵β細胞増殖を介して高血糖を改善する(Recent progress of research toward pancreatic islet regeneration　MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 糖尿病 2018.04.01

山田 哲也, 片桐 秀樹. 膵島再生研究のアップデート　インスリン欠乏性糖尿病マウスモデルにおいてmicroRNAは膵β細胞増殖を介して高血糖を改善する(Recent progress of research toward pancreatic islet regeneration　MicroRNAs improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation). 糖尿病 2018.04.01

坂田 菜摘, 堀内 崇弘, 鳴海 善洋, 木村 朋寛, 林 隆史, 長野 圭介, 劉 克約, 西堀 正洋, 突田 壮平, 山田 哲也, 片桐 秀樹, 白川 龍太郎, 堀内 久徳. メトホルミンはHMGB1に直接結合しその炎症促進作用を抑制する. 生命科学系学会合同年次大会 2017.12.01