Personnel Information

写真a

SASAKI Takehiko


Job title

Professor

Birth date

1969

Mail Address

The inquiry by e-mail is 《here

Homepage URL

http://www.tmd.ac.jp/mri/english/section/pat/index.html

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Pharmaceutical Science, 1992, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Pharmaceutical Sciences, Master's Course, 1994, Completed

  • The University of Tokyo, Graduate School, Division of Pharmaceutical Sciences, Doctor's Course, 1997, Completed

Campus Career 【 display / non-display

  • 2018.03
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Pathophysiology, -, Professor
  • 2018.04
    -
    2019.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, -, -, Lipid Biology, Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, -, -, Professor
  • 2019.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, -, -, Lipid Biology, Professor

External Career 【 display / non-display

  • 2003.05
    -
    2004.10
    , Project Associate Professor
  • 2004.11
    -
    2018.02
    , Professor
 

Published Papers & Misc 【 display / non-display

  • Junko Sasaki, Satoshi Kofuji, Reietsu Itoh, Toshihiko Momiyama, Kiyohiko Takayama, Haruka Murakami, Shinsuke Chida, Yuko Tsuya, Shunsuke Takasuga, Satoshi Eguchi, Ken Asanuma, Yasuo Horie, Kouichi Miura, Elizabeth Michele Davies, Christina Mitchell, Masakazu Yamazaki, Hirokazu Hirai, Tadaomi Takenawa, Akira Suzuki, Takehiko Sasaki. The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death. Nature. 2010.05; 465 (7297): 497-501. ( PubMed, DOI )

  • J Irie-Sasaki, T Sasaki, W Matsumoto, A Opavsky, M Cheng, G Welstead, E Griffiths, C Krawczyk, C D Richardson, K Aitken, N Iscove, G Koretzky, P Johnson, P Liu, D M Rothstein, J M Penninger. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature. 2001.01; 409 (6818): 349-354. ( PubMed, DOI )

  • T Sasaki, J Irie-Sasaki, R G Jones, A J Oliveira-dos-Santos, W L Stanford, B Bolon, A Wakeham, A Itie, D Bouchard, I Kozieradzki, N Joza, T W Mak, P S Ohashi, A Suzuki, J M Penninger. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science. 2000.02; 287 (5455): 1040-1046. ( PubMed )

  • Satoshi Kofuji, Hirotaka Kimura, Hiroki Nakanishi, Hiroshi Nanjo, Shunsuke Takasuga, Hui Liu, Satoshi Eguchi, Ryotaro Nakamura, Reietsu Itoh, Noriko Ueno, Ken Asanuma, Mingguo Huang, Atsushi Koizumi, Tomonori Habuchi, Masakazu Yamazaki, Akira Suzuki, Junko Sasaki, Takehiko Sasaki. INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor. Cancer Discov. 2015.07; 5 (7): 730-739. ( PubMed, DOI )

  • Miki Nishio, Ken-ichi Watanabe, Junko Sasaki, Choji Taya, Shunsuke Takasuga, Ryota Iizuka, Tamas Balla, Masakazu Yamazaki, Hiroshi Watanabe, Reietsu Itoh, Shoko Kuroda, Yasuo Horie, Irmgard Förster, Tak W Mak, Hiromichi Yonekawa, Josef M Penninger, Yasunori Kanaho, Akira Suzuki, Takehiko Sasaki. Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat. Cell Biol.. 2007.01; 9 (1): 36-44. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Junko Sasaki, Eiji Yamamoto, Toshiyoshi Yamamoto, Takehiko Sasaki. Molecular dissection of phosphoinositides. The 14th International Symposium of the Institute Network for Biomedical Sciences 2019 2019.10.03

  • 山本利義、阿部史人、田川博之、佐々木雄彦. リンパ腫細胞株ホスホイノシタイド脂肪酸組成の多変量解析を用いた抗がん剤感受性予測について. 第18回生命科学研究会 2019.06.28

  • 佐々木雄彦. 良い脂質、悪い脂質、普通の脂質. 文の京・最先端生命科学講座 第24回 2019.06.28

  • Junko Sasaki,Satoshi Eguchi,Hiroki Nakanishi,Takehiko Sasaki. Molecular mechanisms of phosphoinositide signaling. 9th Federation of the Asian and Oceanian Physiological Societies Congress 2019.03.27

  • Takehiko Sasaki, Satoshi Kofuji, Shunsuke Takasuga, Junko Sasaki. The lipid phosphatase INPP4B is a tumor suppressor in the context of PTEN insufficiency. Workshop on Frontiers in Phosphatase Research and Drug Discovery 2018.10.24

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