Personnel Information



Job title


Mail Address

Graduate School 【 display / non-display

  • Tokyo University of Science, Graduate School, Division of Engineering, Doctor's Course, Completed

Campus Career 【 display / non-display

  • 2019.05
    Tokyo Medical and Dental University, Institute of Research, Division for Research Innovation, -, Visiting Lecturer
  • 2020.04
    Tokyo Medical and Dental University, Medical Hospital, Central Clinical Facilities, Clinical Research Center, Professor
  • 2020.11
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Public Health, Department of Clinical Biostatistics, Professor

External Career 【 display / non-display

  • 2011.04
    , Assistant Professor
  • 2017.04
    , Project Associate Professor

Academic Activity 【 display / non-display

  • Japanese Journal of Clinical Oncology Reviewer Board Member

Research Areas 【 display / non-display

  • Other


Published Papers & Misc 【 display / non-display

  • Omori H, Hara M, Sobue Y, Kawase Y, Mizukami T, Tanigaki T, Hirata T, Ota H, Okubo M, Hirakawa A, Suzuki T, Kondo T, Leipsic J, NØrgaard B L, Matsuo H.. Determination of the Optimal Measurement Point for Fractional Flow Reserve Derived From CTA Using Pressure Wire Assessment as Reference American Journal of Roentgenology. 2021.06; 216 (6): 1492-1499.

  • Takahashi Y, Nitta J, Kobori A, Sakamoto Y, Nagata Y, Tanimoto K, Matsuo S, Yamane T, Morita N, Satomi K, Inaba O, Murata K, Sasaki Y, Yoshimoto D, Kaneko M, Tanimoto Y, Isogai R, Yamashita S, Sato H, Hanazawa R, Hirakawa A, Goya M, Sasano T.. Alcohol Consumption Reduction and Clinical Outcomes of Catheter Ablation for Atrial Fibrillation Circulation:Arrhythmia and electrophysiology. 2021.06; 14 (6):

  • Sugimoto T, Sakurai T, Akatsu H, Doi T, Fujiwara Y, Hirakara A, Kinoshita F, Kuzuya M, Lee S, Matsuo K, Michikawa M, Ogawa S, Otsuka R, Sato K, Shimada H, Suzuki H, Takechi H, Takeda S, Umegaki H, Wakayama S, Arai H, J-MINT investigators. The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial The Journal of Prevention of Alzheimer's Disease. 2021.06;

  • Ezaki A, Hirakawa A, Hanaoka H, Uyama Y. . Factors Influencing Classifications of Safety Specifications in a Risk Management Plan for Antineoplastic Agents Approved in Japan: A Review and Descriptive Analysis Therapeutic innovation & regulatory science. 2021.06;

  • Yamada S, Hashizume A, Hijikata Y, Ito D, Kishimoto Y, Iida M, Koike H, Hirakawa A, Katsuno M. Ratio of urinary N-terminal titin fragment to urinary creatinine is a novel biomarker for amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry. 2021.03; ( PubMed, DOI )

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Books etc 【 display / non-display

  • Daimon T, Hirakawa A, Matsui S. Dose-Finding Designs for Early Phase Cancer Clinical Trials. Springer, 2019

  • Hirakawa A, Sato H, Daimon T, Matsui S. Modern Dose-Finding Designs for Cancer Phase I Trials: Drug Combinations and Molecularly Targeted. Springer, 2018

  • Hirakawa A, Sato H. Frontiers of Biostatistical Methods and Applications in Clinical Oncology. Springer, 2017

  • Data Monitoring Committees in Clinical Trials: A Practical Perspective. 2017

  • Hirakawa A, Matsui S. Developments in Statistical Evaluation of Clinical Trials. Springer, 2014

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Conference Activities & Talks 【 display / non-display

  • Kojima Y, Shimizu T, Yonemori K, Koyama T, Matsui N, Kamikura M, Tomatsuri S, Sumiyoshi Okuma H, Shimoi T, Noguchi E, Sudo K, Hirakawa A, Sadachi S, Okita N, Nakamura K, Yamamoto N, Fujiwara Y.. A Phase 2 biomarker-driven study evaluating the clinical efficacy of an MDM2 inhibitor, milademetan, in patients with intimal sarcoma, an ultra- rare cancer with a highly life-threatening unmet needs(NCCH1806/MK004). ESMO Congress 2021 2021.09.16

  • Hasegawa K, Nishikawa T, Hirakawa A, Kawasaki M, Tomatsuri S, Nagasaka Y, Nakamura K, Matsumoto K, Mori M, Hirashima Y, Takehara K, Ariyoshi K, Kato T, Yagishita S, Hamada A, Yoshida H, Yonemori K. . Efficacy and safety of trastuzumab deruxtecan in HER2-expressing uterine carcinosarcoma (STATICE TRIAL, NCCH1615): A MULTICENTER, PHASE 2 CLINICAL TRIAL. . ESMO Congress 2021 2021.09.16

  • Kawai A, Nishikawa T, Kawasaki M, Tomatsuri S, Okamura N, Ogawa G, Hirakawa A, Shibata T, Nakamura K, Kakunaga S, Tamura K, Ando M, Ozaki T, Ueda T, Yonemori K. . Efficacy and Safety of Nivolumab Monotherapy in Patients with Unresectable Clear Cell Sarcoma and Alveolar Soft Part Sarcoma (OSCAR t rial, NCCH1510): A Multicenter, Phase 2 Clinical Trial OSCAR.. CTOS 2020 Annual Meeting 2020.11.18

  • Asano J, Hirakawa A.. An Empirical Bayesian Basket Trial Design Accounting for Uncertainties of Homogeneity and Heterogeneity of Treatment Effect among Subpopulations. . ENAR 2020 Spring Meeting 2020.03.22

  • Hirakawa A. An experience of data sharing utilization. 第16回DIA日本年会 2019.11.11

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