Miyamoto, S; Koizumi, M; Hiroki, H; Nishimura, A; Ota, S; Imai, K; Kanegane, H; Morio, T; Honda, H; Takagi, M. A PAX5 GERMLINE VARIANT IN A PATIENT WITH COMMON VARIABLE IMMUNODEFICIENCY COMPLICATED WITH B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA PEDIATRIC BLOOD & CANCER. 2022.11; 69

Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Chika Yamagishi, Moe Tamura, Yosuke Tanaka, Shuhei Asada, Reina Takeda, Akiho Tsuchiya, Xiaonan Wang, Kenichi Yoshida, Yasuhito Nannya, Hiroo Ueno, Ryo Akazawa, Itaru Kato, Takashi Mikami, Kentaro Watanabe, Masahiro Sekiguchi, Masafumi Seki, Shunsuke Kimura, Mitsuteru Hiwatari, Motohiro Kato, Shiro Fukuda, Kenji Tatsuno, Shuichi Tsutsumi, Akinori Kanai, Toshiya Inaba, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Rishi S Kotecha, Mark N Cruickshank, Fumihiko Ishikawa, Tomohiro Morio, Mariko Eguchi, Takao Deguchi, Nobutaka Kiyokawa, Yuki Arakawa, Katsuyoshi Koh, Yuki Aoki, Takashi Ishihara, Daisuke Tomizawa, Takako Miyamura, Eiichi Ishii, Shuki Mizutani, Nicola K Wilson, Berthold Göttgens, Satoru Miyano, Toshio Kitamura, Susumu Goyama, Akihiko Yokoyama, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic. Nat Commun. 2022.08; ( DOI )

Nishimura Akira, Miyamoto Satoshi, Imai Kohsuke, Morio Tomohiro. 先天性免疫異常に対する移植前処置　現在の観点と将来の戦略(Current status and future perspectives of allogeneic hematopoietic cell transplantation for non-malignant diseases: Conditioning regimens for inborn errors of immunity: current perspectives and future strategies) International Journal of Hematology. 2022.07; 116 (1): 7-15. ( ichushi )

Ohkawa Teppei, Nishimura Akira, Kosaki Kenjiro, Aoki-Nogami Yuki, Tomizawa Daisuke, Kashimada Kenichi, Morio Tomohiro, Kato Motohiro, Mizutani Shuki, Takagi Masatoshi. Schuurs-Hoeijmakers症候群におけるPAX3/7-FOXO1融合遺伝子陰性の胞巣型横紋筋肉腫(PAX3/7-FOXO1 fusion-negative alveolar rhabdomyosarcoma in Schuurs-Hoeijmakers syndrome) Journal of Human Genetics. 2022.01; 67 (1): 51-54. ( ichushi )

Miyamoto S, Umeda K, Kurata M, Nishimura A, Yanagimachi M, Ishimura M, Sato M, Shigemura T, Kato M, Sasahara Y, Iguchi A, Koike T, Takahashi Y, Kajiwara M, Inoue M, Hashii Y, Yabe H, Kato K, Atsuta Y, Imai K, Morio T. Hematopoietic Cell Transplantation for Severe Combined Immunodeficiency Patients: a Japanese Retrospective Study. Journal of clinical immunology. 2021.11; 41 (8): 1865-1877. ( PubMed, DOI )

Okano T, Nishimura A, Inoue K, Naruto T, Tokoro S, Tomoda T, Kamiya T, Simbo A, Akutsu Y, Okamoto K, Yeh T, Isoda T, Yanagimachi M, Kajiwara M, Imai K, Kanegane H, Mori M, Morio T, Takagi M. Somatic mutation in RUNX1 underlies mucocutaneus inflammatory manifestations Rheumatology (Oxford). 2021.09; 60 (12): E429-E431. ( PubMed, DOI )

Teppei Ohkawa, Akira Nishimura, Kenjiro Kosaki, Yuki Aoki-Nogami, Daisuke Tomizawa, Kenichi Kashimada, Tomohiro Morio, Motohiro Kato, Shuki Mizutani, Masatoshi Takagi. PAX3/7-FOXO1 fusion-negative alveolar rhabdomyosarcoma in Schuurs-Hoeijmakers syndrome. J Hum Genet. 2021.08; 67 (1): 51-54. ( PubMed, DOI )

Nishimura A, Aoki Y, Ishiwata Y, Ichimura T, Ueyama J, Kawahara Y, Tomoda T, Inoue M, Matsumoto K, Inoue K, Hiroki H, Ono S, Yamashita M, Okano T, Tanaka-Kubota M, Ashiarai M, Miyamoto S, Miyawaki R, Yamagishi C, Tezuka M, Okawa T, Hoshino A, Endo A, Yasuhara M, Kamiya T, Mitsuiki N, Ono T, Isoda T, Yanagimachi M, Tomizawa D, Nagasawa M, Mizutani S, Kajiwara M, Takagi M, Kanegane H, Imai K, Morio T. Hematopoietic Cell Transplantation with Reduced Intensity Conditioning Using Fludarabine/Busulfan or Fludarabine/Melphalan for Primary Immunodeficiency Diseases Journal of Clinical Immunology. 2021.07; 41 (5): 944-957. ( PubMed, DOI )

Nishimura A, Naruto T, Miyamoto S, Grigg A, Bosco JJ, Hoshino A, Amano K, Iwamoto S, Hirayama M, Migita M, Ohara O, Takagi M, Morio T, van Zelm MC, Kanegane H. Genomics analysis of leukaemia predisposition in X-linked agammaglobulinaemia British Journal of Haematology. 2021.06; 193 (6): 1277-1281. ( PubMed, DOI )

Matsumoto K, Hoshino A, Nishimura A, Kato T, Mori Y, Shimomura M, Naito C, Watanabe K, Hamazaki M, Mitsuiki N, Takagi M, Imai K, Nonoyama S, Kanegane H, Morio T. DNA Ligase IV Deficiency Identified by Chance Following Vaccine-Derived Rubella Virus Infection Journal of Clinical Immunology. 2020.11; 40 (8): 1187-1190.

Matsumoto, K; Hoshino, A; Nishimura, A; Kato, T; Mori, Y; Shimomura, M; Naito, C; Watanabe, K; Hamazaki, M; Mitsuiki, N; Takagi, M; Imai, K; Nonoyama, S; Kanegane, H; Morio, T. DNA Ligase IV Deficiency Identified by Chance Following Vaccine-Derived Rubella Virus Infection JOURNAL OF CLINICAL IMMUNOLOGY. 2020.11; 40 (8): 1187-1190. ( PubMed, DOI )

Hoshino A, Nishimura A, Naruto T, Okano T, Matsumoto K, Okamoto K, Shintaku H, Tokoro S, Okamoto H, Wada T, Takagi M, Imai K, Kanegane H, Morio T. High-throughput analysis revealed the unique immunoglobulin gene rearrangements in plasmacytoma-like post-transplant lymphoproliferative disorder British Journal of Haematology. 2020; 189 (4): E162-E166. ( PubMed, DOI )

Nishimura A, Hirabayashi S, Hasegawa D, Yoshida K, Shiraishi Y, Ashiarai M, Hosoya Y, Fujiwara T, Harigae H, Miyano S, Ogawa S, Manabe A. Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome Pediatric Blood and Cancer. 2020; 68 (2): e28799. ( PubMed, DOI )

Tomoda, T; Nishimura, A; Ono, R; Isoda, T; Inoue, M; Kamiya, T; Yanagimachi, M; Imai, K; Kanegane, H; Hasegawa, D; Morio, T; Manabe, A; Takagi, M. Clonal Evolution of Leukemia With MLL-AF9 from Myeloid to T-Lineage PEDIATRIC BLOOD & CANCER. 2019.12; 66 S111.

Nishimura A, Hasegawa D, Hirabayashi S, Kanabuchi S, Yamamoto K, Aiga S, Nishitani M, Hosoya Y, Noguchi Y, Ohki K, Kiyokawa N, Mori S, Manabe A. Very late relapse cases of TCF3-ZNF384-positive acute lymphoblastic leukemia Pediatric Blood and Cancer. 2019; ( PubMed )

Hirabayashi S, Hasegawa D, Yamamoto K, Nishimura A, Hosoya Y, Shuo T, Kiyokawa N, Miura M, Takahashi N, Manabe A. Dasatinib and low-intensity chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia in a child with Down syndrome Pediatric Blood and Cancer. 2019; ( PubMed )

Kubota-Tanaka M, Osumi T, Miura S, Tsujimoto H, Imamura T, Nishimura A, Oki K, Nakamura K, Miyamoto S, Inoue K, Inoue M, Kamiya T, Yanagimachi M, Okano T, Mitsuiki N, Isoda T, Imai K, Kanegane H, Morio T, Kounami S, Endo M, Kato M, Takagi M. B-lymphoblastic lymphoma with TCF3-PBX1 fusion gene Haematologica. 2019; ( PubMed )

Isoda T, Nishimura A, Miyamoto S, Morio T, Takagi M, Murre C. Non-Coding RNA ThymoD Transcription Modulates Nuclear Architecture to Orchestrate T-Cell Fate and Block T-Cell Malignancies. Cancer Sci. 2018.12; 109 346.

Isoda T, Nishimura A, Miyamoto S, Morio T, Takagi M, Murre C. Non-Coding RNA ThymoD Transcription Modulates Nuclear Architecture to Orchestrate T-Cell Fate and Block T-Cell Malignancies. PEDIATRIC BLOOD & CANCER. 2018.11; 65 S4.

Miyamoto Satoshi, Takagi Masatoshi, Nishimura Akira, Tanaka Mari, Ono Shintaro, Ashiarai Miho, Mitsuiki Noriko, Hoshino Akihiro, Yanagimachi Masakatsu, Aoki Yuki, Tomizawa Daisuke, Imai Kohsuke, Kajiwara Michiko, Kanegane Hirokazu, Morio Tomohiro. A 7-year-old Girl who Maintains Complete Remission after Multiple Hematopoietic Cell Transplantation for Frequent Relapse of Infant Leukemia PEDIATRIC BLOOD & CANCER. 2017.11; 64 S92-S93.

Takagi Masatoshi, Ishiwata Yasuyoshi, Aoki Yuki, Miyamoto Satoshi, Hoshino Akihiro, Matsumoto Kazuaki, Nishimura Akira, Tanaka Mari, Yanagimachi Masakatsu, Mitsuiki Noriko, Imai Kohsuke, Kanegane Hirokazu, Kajiwara Michiko, Takikawa Kanako, Mae Tsukasa, Tomita Osamu, Fujimura Junya, Yasuhara Masato, Tomizawa Daisuke, Mizutani Shuki, Morio Tomohiro. 小児の難治性血液悪性疾患に対するクロファラビンとブスルファンを用いたHLAハプロタイプ一致造血幹細胞移植(HLA haploidentical hematopoietic cell transplantation using clofarabine and busulfan for refractory pediatric hematological malignancy) International Journal of Hematology. 2017.05; 105 (5): 686-691. ( ichushi )

Takagi M, Ishiwata Y, Aoki Y, Miyamoto S, Hoshino A, Matsumoto K, Nishimura A, Tanaka M, Yanagimachi M, Mitsuiki N, Imai K, Kanegane H, Kajiwara M, Takikawa K, Mae T, Tomita O, Fujimura J, Yasuhara M, Tomizawa D, Mizutani S, Morio T.. HLA haploidentical hematopoietic cell transplantation using clofarabine and busulfan for refractory pediatric hematological malignancy. Int J Hematol.. 2017;

Dan Tomomasa, Mitsuki Noriko, Isoda Takeshi, Nishimura Akira, Endo Akifumi, Takagi Masatoshi, Kajiwara Michiko, Imai Kohsuke, Morio Tomohiro, Kanegane Hirokazu. Artemis欠損症に対するTCRαβCD19除去移植(Successful TCRABCD19-depleted hematopoietic cell transplantation for a patient with Artemis deficiency). 日本小児血液・がん学会雑誌 2021.10.01

西村 聡, 横山 和明, 成戸 卓也, 中園 博仁, 木村 俊介, 今村 俊彦, 森尾 友宏, 金井 昭教, 松井 啓隆, 梅田 雄嗣, 佐野 秀樹, 小池 隆志, 頼 晋也, 關中 悠仁, 小川 淳, 木下 明俊, 柴 徳生, 三木 瑞香, 木村 文彦, 中山 秀樹, 中沢 洋三, 多賀 崇, 滝 智彦, 足立 壯一, 真部 淳, 康 勝好, 石田 也寸志, 滝田 順子, 東條 有伸, 高木 正稔. 新規の白血病特性を有するmyeloid/natural killer cell precursor acute leukemia(Myeloid/natural killer(NK) cell precursor acute leukemia as a novel distinctive leukemia entity). 日本血液学会学術集会 2021.09.01

足洗 美穂, 西村 聡, 水城 和義, 出口 隆生, 真部 淳, 長谷川 大輔. 芽球性形質細胞様樹状細胞腫瘍の小児に対する造血細胞移植を回避した治療(Treatment in pediatric blastic plasmacytoid dendritic cell neoplasm(BPDCN) without transplantation). 日本血液学会学術集会 2021.09.01

Nishimura Akira, Yokoyama Kazuaki, Naruto Takuya, Morio Tomohiro, Kanai Akinori, Imamura Toshihiko, Koh Katsuyoshi, Ishida Yasushi, Tojo Arinobu, Takagi Masatoshi. Myeloid/Natural killer cell precursor acute leukemiaにおける臨床像とゲノム異常(Clinical feature and genetic alteration of Myeloid/Natural killer cell precursor acute leukemia(MNKPL)). 日本小児血液・がん学会雑誌 2020.10.01

Isoda Takeshi, Nishimura Akira, Morio Tomohiro, Takagi Masatoshi. 血液基礎・核ダイナミクスからnon-coding RNAによる細胞制御　非コードRNA転写による核内局在転換はT細胞への系列決定を誘導しT細胞系腫瘍の抑制に関与する(Non-coding RNA ThymoD transcription specifies T-cell fate and inhibits T-cell malignancies). 日本小児血液・がん学会雑誌 2020.10.01

Nishimura Akira, Miyakawa Yuichi, Murakoshi Miki, Shimbo Asami, Ishiguro Rika, Kajiwara Michiko, Shibuya Atsushi, Ogura Hiromi, Kanno Hitoshi, Koh Katsuyoshi, Minosaki Yoshihiro, Nishioka Masato, Shimohira Masayuki. ANK1変異とSLC4A1バリアントを有する重症貧血が遷延する遺伝性球状赤血球症の1例(A case of hereditary spherocytosis with ANK1 mutation and SLC4A1 variant with persistent severe anemia). 日本小児血液・がん学会雑誌 2019.10.01

Tomoda Takahiro, Nishimura Akira, Ono Rintaro, Isoda Takeshi, Inoue Maiko, Kamiya Takahiro, Yanagimachi Masakatsu, Imai Kohsuke, Kanegane Hirokazu, Hasegawa Daisuke, Morio Tomohiro, Manabe Atsushi, Takagi Masatoshi. 急性骨髄性白血病からT細胞型急性リンパ性白血病へclonal evolutionを起こしたMLL-AF9陽性乳児白血病の一例(Clonal evolution of leukemia with MLL-AF9 from myeloid to T-lineage). 日本小児血液・がん学会雑誌 2019.10.01

Ashiarai Miho, Hasegawa Daisuke, Nishimura Akira, Mizuki Kazuyoshi, Yamamoto Kaoru, Yamamoto Shunsuke, Ono Rintaro, Hirabayashi Shinsuke, Hosoya Yosuke, Manabe Atsushi. 肝脾T細胞リンパ腫に対するハプロ末梢血幹細胞移植(Haploidentical hematopoietic stem cell transplantation for hepatosplenic T-cell lymphoma). 日本小児血液・がん学会雑誌 2019.10.01

Nishimura Akira, Aoki Yuki, Ishiwata Yasuyoshi, Inoue Maiko, Ichimura Takuya, Ueyama Junichi, Matsumoto Kazuaki, Inoue Kento, Hiroki Haruka, Ono Shintaro, Okano Tsubasa, Tanaka Mari, Miyamoto Satoshi, Ashiarai Miho, Miyawaki Reiji, Yamagishi Chika, Tezuka Mari, Okawa Teppei, Hoshino Akihiro, Endo Akifumi, Yasuhara Masato, Kamiya Takahiro, Mitsuiki Noriko, Ono Toshiaki, Yanagimachi Masakatsu, Isoda Takeshi, Tomizawa Daisuke, Nagasawa Masayuki, Kajiwara Michiko, Takagi Masatoshi, Mizutani Shuki, Kanegane Hirokazu, Imai Kohsuke, Morio Tomohiro. Hematopoietic cell transplantation with reduced intensity conditioning regimen using fludarabine/busulfan and fludarabine/melphalan for primary immunodeficiency diseases . The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation 2019.03.24 Frankfurt

Nishimura A, Yokoyama K, Yamagishi C, Naruto T, Morio T, Kanai A, Matsui H, Higuchi N, Takada A, Okuno H, Saito S, Karakawa S, Kobayashi S, Sano H, Koike T, Hasegawa D, Fujisaki H, Hasegawa D, Koike K, Ogawa A, Kinoshita A, Shiba N, Miki M, Nakayama H, Nakazawa Y, Imamura T, Taga T, Adachi S, Koh K, Manabe A, Taki T, Ishida Y, Tojo A, Takagi M. Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia. 60st American society of Hematology Annual Meeting & Exposition 2018.12.02 San Diego

Isoda T, Nishimura A, Miyamoto S, Morio T, Takagi M, Murre C. Non-Coding RNA thymod transcription modulates nuclear architecture to Orchestratet-Cell fate and block T-Cell malignancies. SIOP2018 2018.11.17 Kyoto

Nishimura Akira, Hirabayashi Shinsuke, Yamamoto Shunsuke, Aiga Saori, Nishitani Misa, Hosoya Yosuke, Mori Shinichiro, Hasegawa Daisuke, Manabe Atsushi. Diamond-Blackfan貧血に対する強度減弱前処置を用いた骨髄移植(Bone marrow transplantation with reduced intensity conditioning for Diamond-Blackfan anemia). 日本小児血液・がん学会雑誌 2018.10.01

Hirabayashi Shinsuke, Yamamoto Shunsuke, Yamamoto Kaoru, Yamamoto Kazuki, Aiga Saori, Daida Atsuro, Ono Rintaro, Ashiarai Miho, Nishimura Akira, Hosoya Yosuke, Hasegawa Daisuke, Manabe Atsushi. ダサチニブ併用低減集中化学療法を用いたダウン症候群合併フィラデルフィア染色体陽性急性リンパ性白血病(Dasatinib-combined less intensive chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia in Down syndrome). 日本小児血液・がん学会雑誌 2018.10.01

平林 真介, 西村 聡, 山本 薫, 山本 俊亮, 細谷 要介, 野崎 太希, 長谷川 大輔, 真部 淳. 急性前骨髄球性白血病に生じた髄注後の亜急性白質脳症の一例(Subacute leukoencephalopathy after intrathecal methotrexate in a patient with APL). 臨床血液 2018.09.01

磯田 健志, 西村 聡, 宮本 智史, 森尾 友宏, 高木 正稔, ミュア・コーネリウス . 非コードRNA転写による核内構造変換はT細胞への系列決定を誘導しT細胞系腫瘍の抑制に寄与する(ThymoD modulates nuclear architecture to specify T-cell fate and blocks T-cell malignancies). 臨床血液 2018.09.01

西村 聡, 平林 真介, 金淵 昭一郎, 山本 薫, 相賀 咲央莉, 細谷 要介, 大木 健太郎, 清河 信敬, 長谷川 大輔, 真部 淳. 診断後10年で再発をきたしたTCF3-ZNF384陽性急性リンパ性白血病の1例(TCF3-ZNF384 positive acute lymphoblastic leukemia recurring 10 years after diagnosis). 臨床血液 2018.09.01

Miyamoto Satoshi, Takagi Masatoshi, Nishimura Akira, Tanaka Mari, Ono Shintaro, Ashiarai Miho, Mitsuiki Noriko, Hoshino Akihiro, Yanagimachi Masakatsu, Aoki Yuki, Tomizawa Daisuke, Imai Kohsuke, Kajiwara Michiko, Kanegane Hirokazu, Morio Tomohiro. 頻回再発に対する複数回造血細胞移植により寛解を維持している乳児白血病の7歳女児例(A 7-year-old girl who maintains complete remission after multiple hematopoietic cell transplantation for frequent relapse of infant leukemia). 日本小児血液・がん学会雑誌 2017.10.01

Nishimura Akira, Arakawa Ayumu, Hosoya Yosuke, Hirabayashi Shinsuke, Yoshihara Hiroki, Kikuta Atsushi, Matsumoto Seiichi, Kawamori Jiro, Hasegawa Daisuke, Kumamoto Tadashi, Ogawa Chitose, Manabe Atsushi. 骨盤内原発Ewing肉腫における集学的治療の検討(Multimodality treatment for pelvic Ewing sarcoma). 日本小児血液・がん学会雑誌 2017.10.01

Matsumoto Kazuaki, Takagi Masatoshi, Ishiwata Yasuyoshi, Aoki Yuki, Miyamoto Satoshi, Hoshino Akihiro, Nishimura Akira, Tanaka Mari, Yanagimachi Masakatsu, Mitsuiki Noriko, Imai Kohsuke, Kanegane Hirokazu, Kajiwara Michiko, Takikawa Kanako, Mae Tsukasa, Tomita Osamu, Fujimura Junya, Yasuhara Masato, Tomizawa Daisuke, Mizutani Shuki, Morio Tomohiro. 小児難治性血液腫瘍に対するクロファラビンおよびブスルファンを用いた前処置による血縁HLA半合致移植(HLA haploidentical HCT using clofarabine and busulfan for refractory pediatric leukemia). 臨床血液 2017.09.01