Personnel Information

写真a

IKEDA SADAKATSU


Job title

Professor

Research Areas, Keywords

Medical oncology, Precision Cancer Medicine
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Graduating School 【 display / non-display 】

  • Hokkaido University, Faculty of Medicine, Graduated

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Degree 【 display / non-display 】

  • Ph.D., Tokyo Medical and Dental University

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Campus Career 【 display / non-display 】

  • 2016.03
    -
    2017.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Cancer Center， Project Assistant Professor
  • 2017.04
    -
    2018.12
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Cancer Center， Project Junior Associate Professor
  • 2019.01
    -
    2019.10
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Cancer Center， Associate Professor
  • 2019.11
    -
    2021.09
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Center for Innovative Cancer Treatment， Associate Professor
  • 2021.10
    -
    2022.03
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Integrated Facilities， Center for Innovative Cancer Treatment， Associate Professor
  • 2022.04
    -
    2024.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Comprehensive Patient Care， Clinical Oncology， Associate Professor
  • 2024.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Comprehensive Patient Care， Clinical Oncology， Professor

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External Career 【 display / non-display 】

  • 2014.08
    -
    2016.02
    , Assistant Professor
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Research Areas 【 display / non-display 】

  • Medical biochemistry

  • General internal medicine

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  1. Miyagi M, Inoue G, Yoshii T, Egawa S, Sakai K, Kusano K, Nakagawa Y, Hirai T, Wada K, Katsumi K, Kimura A, Furuya T, Nagoshi N, Kanchiku T, Nagamoto Y, Oshima Y, Nakashima H, Ando K, Takahata M, Mori K, Nakajima H, Murata K, Matsunaga S, Kaito T, Yamada K, Kobayashi S, Kato S, Ohba T, Inami S, Fujibayashi S, Katoh H, Kanno H, Koda M, Takahashi H, Ikeda S, Imagama S, Kawaguchi Y, Takeshita K, Matsumoto M, Takaso M, Okawa A, Yamazaki M. Residual Neuropathic Pain in Postoperative Patients With Cervical Ossification of Posterior Longitudinal LigamentRisk Factors for Residual Neuropathic Pain. Clinical spine surgery. 2023.02; ( PubMed, DOI )

  2. Kage H, Shinozaki-Ushiku A, Ishigaki K, Sato Y, Tanabe M, Tanaka S, Tanikawa M, Watanabe K, Kato S, Akagi K, Uchino K, Mitani K, Takahashi S, Miura Y, Ikeda S, Kojima Y, Watanabe K, Mochizuki H, Yamaguchi H, Kawazoe Y, Kashiwabara K, Kohsaka S, Tatsuno K, Ushiku T, Ohe K, Yatomi Y, Seto Y, Aburatani H, Mano H, Miyagawa K, Oda K. Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan. Cancer science. 2023.01; 114 (4): 1710-1717. ( PubMed, DOI )

  3. Lazar V, Girard N, Raymond E, Martini JF, Galbraith S, Raynaud J, Bresson C, Solomon B, Magidi S, Nechushtan H, Onn A, Berger R, Chen H, Al-Omari A, Ikeda S, Lassen U, Sekacheva M, Felip E, Tabernero J, Batist G, Spatz A, Pramesh CS, Girard P, Blay JY, Philip T, Berindan-Neagoe I, Porgador A, Rubin E, Kurzrock R, Schilsky RL. Transcriptomics in Tumor and Normal Lung Tissues Identify Patients With Early-Stage Non-Small-Cell Lung Cancer With High Risk of Postsurgery Recurrence Who May Benefit From Adjuvant Therapies. JCO precision oncology. 2022.09; 6 e2200072. ( PubMed, DOI )

  4. Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Ogino Kei, Okamoto Kentaro, Yamaguchi Takeshi, Watanabe Shun, Nakajima Masanobu, Morita Shinji, Nakamura Takatoshi, Suzuki Kan, Tsuchioka Takashi, Kojima Kazuyuki, Miyake Satoshi, Takagi Masatoshi, Ikeda Sadakatsu. A Pilot Study of Comprehensive Genomic Profiling for Pediatric and Adolescent and Young Adult Solid Tumor Patients in Japan(和訳中) Dokkyo Medical Journal. 2022.03; 1 (1): 56-62. ( ichushi )

  5. Onishi Iichiroh, Kirimura Susumu, Wakejima Ryo, Okubo Kenichi, Odai Tamami, Kakuta Ryota, Kano Yoshihito, Ikeda Sadakatsu, Akashi Takumi, Kitagawa Masanobu. Primary pulmonary choriocarcinoma with a genomic sequence(和訳中) Pathology International. 2022.02; 72 (2): 141-143. ( ichushi )

  6. Yatabe Yasushi, Goto Koichi, Matsumoto Shingo, Hatanaka Yutaka, Arakane Naoko, Ikeda Sadakatsu, Inoue Akira, Kinoshita Ichiro, Kimura Hideharu, Sakamoto Tomohiro, Satouchi Miyako, Shimizu Junichi, Sunami Kuniko, Tsuta Koji, Toyooka Shinichi, Nishio Kazuto, Nishino Kazumi, Mikubo Masashi, Yokose Tomoyuki, Dosaka-Akita Hirotoshi. METex14 Skipping Testing Guidance for Lung Cancer Patients: The Guidance from the Biomarker Committee, the Japan Lung Cancer Society(和訳中) 肺癌. 2021.10; 61 (5): 361-370. ( ichushi )

  7. Munkhdelger Jijgee, Shimooka Tomoko, Koyama Yoshinori, Ikeda Sadakatsu, Mikami Yoshiki, Fukuoka Junya, Hori Takashi, Bychkov Andrey. Basaloid Squamous Cell Carcinoma of the Uterine Cervix: Report of a Case With Molecular Analysis INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY. 2021.04; 29 (7): 1066896921997132-774. ( PubMed, DOI )

  8. Kato Shumei, McFall Thomas, Takahashi Kenta, Bamel Kasey, Ikeda Sadakatsu, Eskander Ramez N., Plaxe Steven, Parker Barbara, Stites Edward, Kurzrock Razelle. KRAS-Mutated, Estrogen Receptor-Positive Low-Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery ONCOLOGIST. 2021.04; 26 (4): E530-E536. ( PubMed, DOI )

  9. Nakamura Kohei, Aimono Eriko, Oba Junna, Hayashi Hideyuki, Tanishima Shigeki, Hayashida Tetsu, Chiyoda Tatsuyuki, Kosaka Takeo, Hishida Tomoyuki, Kawakubo Hirohumi, Kitago Minoru, Okabayashi Koji, Funakoshi Takeru, Okita Hajime, Ikeda Sadakatsu, Takaishi Hiromasa, Nishihara Hiroshi. Estimating copy number using next-generation sequencing to determine ERBB2 amplification status MEDICAL ONCOLOGY. 2021.04; 38 (4): 36. ( PubMed, DOI )

  10. Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Takahashi Kenta, Kumaki Yuichi, Mitsumura Takahiro, Kimura Koichiro, Onishi Iichiro, Takemoto Akira, Ban Daisuke, Ono Hiroaki, Kudo Atsushi, Oshima Noriko, Ogino Kei, Watanabe Shun, Tani Yukiko, Yamaguchi Takeshi, Nakajima Masanobu, Morita Shinji, Yamaguchi Satoru, Takagi Masatoshi, Ishikawa Toshiaki, Nakagawa Tsuyoshi, Okamoto Kentaro, Uetake Hiroyuki, Tanabe Minoru, Miyake Satoshi, Tsuchioka Takashi, Kojima Kazuyuki, Ikeda Sadakatsu. A Pilot Study Analyzing the Clinical Utility of Comprehensive Genomic Profiling Using Plasma Cell-Free DNA for Solid Tumor Patients in Japan (PROFILE Study) ANNALS OF SURGICAL ONCOLOGY. 2021.03; 28 (13): 8497-8505. ( PubMed, DOI )

  11. Matsudera Shotaro, Kano Yoshihito, Ikeda Sadakatsu. ASO Author Reflections: Impact of Liquid Biopsy Using Plasma Cell-Free DNA in Solid Tumors in Japan ANNALS OF SURGICAL ONCOLOGY. 2021.03; 28 (13): 8506-8507. ( PubMed, DOI )

  12. Naito Yoichi, Aburatani Hiroyuki, Amano Toraji, Baba Eishi, Furukawa Toru, Hayashida Tetsu, Hiyama Eiso, Ikeda Sadakatsu, Kanai Masashi, Kato Motohiro, Kinoshita Ichiro, Kiyota Naomi, Kohno Takashi, Kohsaka Shinji, Komine Keigo, Matsumura Itaru, Miura Yuji, Nakamura Yoshiaki, Natsume Atsushi, Nishio Kazuto, Oda Katsutoshi, Oda Naoyuki, Okita Natsuko, Oseto Kumiko, Sunami Kuniko, Takahashi Hideaki, Takeda Masayuki, Tashiro Shimon, Toyooka Shinichi, Ueno Hideki, Yachida Shinichi, Yoshino Takayuki, Tsuchihara Katsuya. Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1) INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY. 2021.02; 26 (2): 233-283. ( PubMed, DOI )

  13. Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Ogino Kei, Okamoto Kentaro, Tsuchioka Takashi, Kojima Kazuyuki, Takagi Masatoshi, Ikeda Sadakatsu. Clinical Utility of Comprehensive Genomic Profiling for Pediatric and AYA Solid Tumor Patients PEDIATRIC BLOOD & CANCER. 2020.12; 67

  14. Aoyagi Yasuko, Kano Yoshihito, Ban Daisuke, Tokunaga Masanori, Nakajima Yasuaki, Uetake Hiroyuki, Tanabe Minoru, Miyake Satoshi, Kinugasa Yusuke, Ikeda Sadakatsu. 消化器外科とゲノム医療の将来展望　進行性固形腫瘍患者における包括的ゲノムプロファイリングの臨床的有用性(Future perspectives of cancer genomic medicine in gastroenterological surgery　Clinical utility of multiple genomic testing in patients with advanced solid tumor) 日本消化器外科学会総会. 2020.12; 75回 WS14-3. ( ichushi )

  15. Ono Hiroaki, Ikeda Sadakatsu, Ishikawa Yoshiya, Watanabe Shuichi, Akahoshi Keiichi, Ogawa Kosuke, Ban Daisuke, Kudo Atsushi, Miyake Satoshi, Tanabe Minoru. 消化器外科とゲノム医療の将来展望　HBP悪性腫瘍におけるゲノムシークエンスの横断研究(Future perspectives of cancer genomic medicine in gastroenterological surgery　Cross-sectional study of genomic sequencing in HBP malignancies) 日本消化器外科学会総会. 2020.12; 75回 WS14-11. ( ichushi )

  16. 松寺 翔太郎, 加納 嘉人, 青柳 康子, 遠山 皓基, 木村 浩一朗, 大西 威一郎, 竹本 暁, 荻野 恵, 岡本 健太郎, 植竹 宏之, 田邉 稔, 三宅 智, 土岡 丘, 小嶋 一幸, 池田 貞勝. Liquid biopsyが変えるがん治療　がんゲノム医療におけるリキッドバイオプシーの臨床的有用性の検討 日本癌治療学会学術集会抄録集. 2020.10; 58回 WS12-4. ( ichushi )

  17. Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Ogino Kei, Okamoto Kentaro, Tsuchioka Takashi, Kojima Kazuyuki, Takagi Masatoshi, Ikeda Sadakatsu. 小児・AYA世代の進行再発固形がん患者におけるがん遺伝子パネル検査の臨床的有用性の検討(Clinical utility of comprehensive genomic profiling for pediatric and AYA solid tumor patients) 日本小児血液・がん学会雑誌. 2020.10; 57 (4): 243. ( ichushi )

  18. Yatabe Y, Sunami K, Goto K, Nishio K, Aragane N, Ikeda S, Inoue A, Kinoshita I, Kimura H, Sakamoto T, Satouchi M, Shimizu J, Tsuta K, Toyooka S, Nishino K, Hatanaka Y, Matsumoto S, Mikubo M, Yokose T, Dosaka-Akita H. Multiplex gene-panel testing for lung cancer patients. Pathology international. 2020.09; ( PubMed, DOI )

  19. Takahashi Kenta, Ishibashi Eri, Kubo Toshio, Harada Yohei, Hayashi Hideyuki, Kano Masayuki, Shimizu Yasushi, Shirota Hidekazu, Mori Yukiko, Muto Manabu, Ishioka Chikashi, Dosaka-Akita Hirotoshi, Matsubara Hisahiro, Nishihara Hiroshi, Sueoka-Aragane Naoko, Toyooka Shinichi, Hirakawa Akihiro, Tateishi Ukihide, Miyake Satoshi, Ikeda Sadakatsu. A phase 2 basket trial of combination therapy with trastuzumab and pertuzumab in patients with solid cancers harboring human epidermal growth factor receptor 2 amplification (JUPITER trial) MEDICINE. 2020.08; 99 (32): e21457. ( PubMed, DOI )

  20. Iijima Y, Sakakibara R, Ishizuka M, Honda T, Shirai T, Okamoto T, Tateishi T, Sakashita H, Tamaoka M, Takemoto A, Kumaki Y, Ikeda S, Miyazaki Y. Notable response to nivolumab during the treatment of SMARCA4-deficient thoracic sarcoma: a case report. Immunotherapy. 2020.05; ( PubMed, DOI )

  21. Takahashi Kenta, Gen Yasuyuki, Tanimoto Kousuke, Kudo Atsushi, Oshima Noriko, Ban Daisuke, Takemoto Akira, Onishi Iichiro, Kumaki Yuichi, Yokobori Junko, Takamine Eriko, Kano Yoshihito, Miyake Satoshi, Miyasaka Naoyuki, Tanabe Minoru, Inazawa Johji, Ikeda Sadakatsu. Clinical impact of hemizygous deletion detection and panel-size in comprehensive genomic profiling. JOURNAL OF CLINICAL ONCOLOGY. 2020.05; 38 (15):

  22. Kato S, Okamura R, Kumaki Y, Ikeda S, Nikanjam M, Eskander R, Goodman A, Lee S, Glenn ST, Dressman D, Papanicolau-Sengos A, Lenzo FL, Morrison C, Kurzrock R. Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. Oncoimmunology. 2020; 9 (1): 1708065. ( PubMed, DOI )

  23. Peled N., Okuma H., Rotem O., Dudnik E., Ikeda S., Stemmer S. M., Olsen S.. Circulating tumour DNA (ctDNA) identifies actionable genetic alterations in Middle Eastern and Asian (MEA) patients diagnosed with carcinoma of unknown primary (CUP) ANNALS OF ONCOLOGY. 2019.11; 30

  24. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. Genomic sequencing in HBP malignancies(和訳中) 日本消化器病学会雑誌. 2019.11; 116 (臨増大会): A893. ( ichushi )

  25. Takahashi K., Kato S., Bamel K., Ikeda S., Plaxe S., Parker B., Kurzrock R.. EXCEPTIONAL RESPONSE WITH COMBINED ANTI-HORMONE AND MEK INHIBITOR THERAPY IN A PATIENT WITH HORMONE RECEPTOR-POSITIVE OVARIAN CANCER AND ISOLATED KRAS ALTERATION. IMPLICATIONS FOR A PRECISION MEDICINE STRATEGY INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2019.11; 29 A524. ( DOI )

  26. Oshima N., Takahashi K., Nakamura R., Yoshino Y., Wakana K., Ikeda S., Miyasaka N.. CANCER GENOMIC AND PERSONALIZED MEDICINE FOR GYNECOLOGIC TUMORS IN OUR HOSPITAL INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2019.11; 29 A416. ( DOI )

  27. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性疾患に関するゲノムシークエンス解析(Genomic sequencing in HBP malignancies) 日本消化器外科学会雑誌. 2019.11; 52 (Suppl.2): 306. ( ichushi )

  28. Ogura T, Takigawa N, Tomii K, Kishi K, Inoue Y, Ichihara E, Homma S, Takahashi K, Akamatsu H, Ikeda S, Inase N, Iwasawa T, Ohe Y, Ohta H, Onishi H, Okamoto I, Ogawa K, Kasahara K, Karata H, Kishimoto T, Kitamura Y, Gemma A, Kenmotsu H, Sakashita H, Sakamoto S, Sekine K, Takiguchi Y, Tada Y, Toyooka S, Nakayama Y, Nishioka Y, Hagiwara K, Hanibuchi M, Fukuoka J, Minegishi Y, Yanagihara T, Yamamoto N, Yamamoto H, Gaga M, Fong KM, Powell CA, Kiura K, DLD/TO Assemblies of JRS. Summary of the Japanese Respiratory Society statement for the treatment of lung cancer with comorbid interstitial pneumonia. Respiratory investigation. 2019.11; 57 (6): 512-533. ( PubMed, DOI )

  29. 武藤 学, 金井 雅史, 鶴山 竜昭, 松本 繁巳, 豊岡 伸一, 秋田 弘俊, 松原 久裕, 西原 広史, 末岡 榮三朗, 池田 貞勝. バイオバンキングが切り拓く新しいがん研究　わが国におけるクリニカルバイオバンクネットワークの構築(Innovative cancer research based on biobanking　Clinical biobank network in Japan) 日本癌学会総会記事. 2019.09; 78回 S11-4. ( ichushi )

  30. Kaseb AO, Sánchez NS, Sen S, Kelley RK, Tan BR, Bocobo AG, Lim KH, Abdel-Wahab R, Uemura MI, Carmagnani Pestana R, Qiao W, Xiao L, Morris J, Amin HM, Hassam MM, Rashid A, Banks KC, Lanman RB, Talasaz A, Mills Shaw KR, George B, Haque A, Raghav K, Wolf RA, Yao JC, Meric-Bernstam F, Ikeda S, Kurzrock R. Molecular profiling of hepatocellular carcinoma using circulating cell-free DNA. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019.07; 25 (20): 6107-6118. ( PubMed, DOI )

  31. Yuichi Kumaki, Sadakatsu Ikeda, Thereasa A. Rich, Jing Zhao, Takayuki Yoshino, Byoung Chul Cho, Nir Peled, Ji-Youn Han, Yukimasa Shiotsu, Aleksandra Franovic, Victoria M. Raymond, Razelle Kurzrock, Richard B. Lanman, Jeeyun Lee, Tony S. K. Mok. Comprehensive genomic profiling of circulating cell-free DNA (cfDNA) distinguishes focal amplification (amp) from aneuploidy among MET amps in diverse advanced cancer types. Journal of Clinical Oncology. 2019.05; 37 (15): 3046. ( DOI )

  32. Kumaki Yuichi, Ikeda Sadakatsu, Rich Thereasa A., Zhao Jing, Yoshino Takayuki, Cho Byoung Chul, Peled Nir, Han Ji-Youn, Shiotsu Yukimasa, Franovic Aleksandra, Raymond Victoria M., Kurzrock Razelle, Lanman Richard B., Lee Jeeyun, Mok Tony S. K.. Comprehensive genomic profiling of circulating cell-free DNA (cfDNA) distinguishes focal amplification (amp) from aneuploidy among MET amps in diverse advanced cancer types. JOURNAL OF CLINICAL ONCOLOGY. 2019.05; 37 (15):

  33. Ikeda S., Kumaki Y., Rich T. A., Shiotsu Y., Franovic A., Raymond V. M., Kurzrock R., Lanman R. B., Lee J., Mok T. S. K.. Circulating cell-free DNA molecular profiling among east Asian patients reveals activating MET alterations are common in diverse advanced cancer types ANNALS OF ONCOLOGY. 2018.11; 29 116.

  34. Ikeda Sadakatsu, Elkin Sheryl K, Tomson Brett N, Carter Jennifer L, Kurzrock Razelle. Next-generation sequencing of prostate cancer: genomic and pathway alterations, potential actionability patterns, and relative rate of use of clinical-grade testing. Cancer Biol Ther. 2018.10; 1-8. ( PubMed, DOI )

  35. Machiels J-P., Licitra L., Tao Y. G., Yen C-J., Rischin D., Waldron J. N., Burtness B. A., Gregoire V., Agarwala S. S., Yorio J., Delord J-P., Aksoy S., Ikeda S., Hong R-L., Ge J. Y., Brown H., Bidadi B., Siu L. L.. KEYNOTE-412: Phase III study of pembrolizumab plus chemoradiation vs chemoradiation alone for locally advanced head and neck squamous cell carcinoma (HNSCC) ANNALS OF ONCOLOGY. 2018.10; 29 398.

  36. Takahashi K., Oshima N., Nakamura R., Wakana K., Miyake S., Miyasaka N., Ikeda S.. OVARIAN MIXED BRENNER-MUCINOUS BORDERLINE TUMOR WITH BRAF V600E MUTATION INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2018.09; 28 848.

  37. Siu Lillian L., Licitra Lisa, Tao Yun Gan, Yen Chia-Jui, Rischin Danny, Waldron John, Burtness Barbara, Gregoire Vincent, Agarwala Sanjiv, Yorio Jeffrey, DeLord Jean-Pierre, Aksoy Sercan, Ikeda Sadakatsu, Hong Ruey-Long, Ge Joy Yang, Brown Holly, Bidadi Behzad, Machiels Jean-Pascal. KEYNOTE-412: Pembrolizumab plus chemoradiation vs chemoradiation alone for locally advanced head and neck squamous cell carcinoma CANCER RESEARCH. 2018.07; 78 (13): ( DOI )

  38. Ikeda Sadakatsu, Schwaederle Maria, Mohindra Mandakini, Jardim Denis L. Fontes, Kurzrock Razelle. MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis JOURNAL OF HEMATOLOGY & ONCOLOGY. 2018.06; 11 76. ( DOI )

  39. Ikeda Sadakatsu, Schwaederle Maria, Mohindra Mandakini, Fontes Jardim Denis L, Kurzrock Razelle. MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis. J Hematol Oncol. 2018.06; 11 (1): 76. ( PubMed, DOI )

  40. Ikeda Sadakatsu, Tsigelny Igor F., Skjevik Age A., Kono Yuko, Mendler Michel, Kuo Alexander, Sicklick Jason K., Heestand Gregory, Banks Kimberly C., Talasaz AmirAli, Lanman Richard B., Lippman Scott, Kurzrock Razelle. Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma ONCOLOGIST. 2018.05; 23 (5): 586-593. ( PubMed, DOI )

  41. Machiels Jean-Pascal H., Licitra Lisa F., Tao Yungan, Yen Chia-Jui, Rischin Danny, Waldron John, Burtness Barbara, Gregoire Vincent, Agarwala Sanjiv S., Yorio Jeffrey, Delord Jean-Pierre, Aksoy Sercan, Ikeda Sadakatsu, Hong Ruey-Long, Ge Joy Yang, Brown Holly M., Bidadi Behzad, Siu Lillian L.. Pembrolizumab plus chemoradiation vs chemoradiation alone for locally advanced head and neck squamous cell carcinoma: The phase 3 KEYNOTE-412 study. JOURNAL OF CLINICAL ONCOLOGY. 2018.05; 36 (15):

  42. Ikeda Sadakatsu, Lim Jordan S., Kurzrock Razelle. Analysis of Tissue and Circulating Tumor DNA by Next-Generation Sequencing of Hepatocellular Carcinoma: Implications for Targeted Therapeutics MOLECULAR CANCER THERAPEUTICS. 2018.05; 17 (5): 1114-1122. ( PubMed, DOI )

  43. Kato Shumei, Kurasaki Kellie, Ikeda Sadakatsu, Kurzrock Razelle. Rare Tumor Clinic: The University of California San Diego Moores Cancer Center Experience with a Precision Therapy Approach ONCOLOGIST. 2018.02; 23 (2): 171-178. ( PubMed, DOI )

  44. Riviere Paul, Fanta Paul T., Ikeda Sadakatsu, Baumgartner Joel, Heestand Gregory M., Kurzrock Razelle. The Mutational Landscape of Gastrointestinal Malignancies as Reflected by Circulating Tumor DNA MOLECULAR CANCER THERAPEUTICS. 2018.01; 17 (1): 297-305. ( PubMed, DOI )

  45. Machiels J-P., Yen C-J., Licitra L., Rischin D., Waldron J., Burtness B., Gregoire V., Tao Y. G., Yorio J., Aksoy S., Ikeda S., Hong R-L., Ge J. Y., Brown H., Bidadi B., Siu L.. Phase 3 KEYNOTE-412 trial: Pembrolizumab plus chemoradiation (CRT) vs CRT alone for locally advanced head and neck squamous cell carcinoma (LA-HNSCC) ANNALS OF ONCOLOGY. 2017.12; 28

  46. Yen C-J., Machiels J-P., Licitra L., Rischin D., Waldron J., Burtness B., Gregoire V., Tao Y., Yorio J., Aksoy S., Ikeda S., Hong R-L., Ge J. Y., Brown H., Bidadi B., Siu L.. KEYNOTE-412: Phase 3 trial of pembrolizumab plus chemoradiation (CRT) vs CRT alone for locally advanced head and neck squamous cell carcinoma (LA-HNSCC) ANNALS OF ONCOLOGY. 2017.11; 28

  47. Machiels Jean-Pascal, Yen Chia-Jui, Licitra Lisa, Rischin Danny, Waldron John, Burtness Barbara, Gregoire Vincent, Agarwala Sanjiv, Tao Yun Gan, Yorio Jeffrey, Aksoy Sercan, Ikeda Sadakatsu, Hong Ruey-Long, Ge Joy Yang, Brown Holly, Bidadi Behzad, Siu Lillian. Phase 3 study of Pembrolizumab plus Chemoradiation (CRT) vs CRT alone for locally advanced head and neck squamous cell carcinoma (LA-HNSCC): KEYNOTE-412 JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2017.11; 5

  48. Schwaederle Maria, Chattopadhyay Ranajoy, Kato Shumei, Fanta Paul T., Banks Kimberly C., Choi In Sil, Piccioni David E., Ikeda Sadakatsu, Talasaz AmirAli, Lanman Richard B., Bazhenova Lyudmila, Kurzrock Razelle. Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing CANCER RESEARCH. 2017.10; 77 (19): 5419-5427. ( DOI )

  49. Schwaederle Maria C, Patel Sandip P, Husain Hatim, Ikeda Megumi, Lanman Richard B, Banks Kimberly C, Talasaz AmirAli, Bazhenova Lyudmila, Kurzrock Razelle. Utility of Genomic Assessment of Blood-Derived Circulating Tumor DNA (ctDNA) in Patients with Advanced Lung Adenocarcinoma. Clin Cancer Res. 2017.09; 23 (17): 5101-5111. ( PubMed, DOI )

  50. Khemlina Galina, Ikeda Sadakatsu, Kurzrock Razelle. The biology of Hepatocellular carcinoma: implications for genomic and immune therapies MOLECULAR CANCER. 2017.08; 16 149. ( PubMed, DOI )

  51. Cohen Philip R., Kato Shumei, Goodman Aaron M., Ikeda Sadakatsu, Kurzrock Razelle. Appearance of New Cutaneous Superficial Basal Cell Carcinomas during Successful Nivolumab Treatment of Refractory Metastatic Disease: Implications for Immunotherapy in Early Versus Late Disease INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2017.08; 18 (8): 1663. ( DOI )

  52. Schwaederle Maria Clemence, Chattopadhyay Ranajoy, Kato Shumei, Fanta Paul T., Banks Kimberly, Piccioni David Eric, Ikeda Sadakatsu, Talasaz AmirAli, Lanman Richard B., Bazhenova Lyudmila, Kurzrock Razelle. Genomic alterations in 670 patients with diverse cancers analyzed by next-generation sequencing (NGS) of circulating tumor DNA (ctDNA). JOURNAL OF CLINICAL ONCOLOGY. 2017.05; 35 (15): ( DOI )

  53. Kato Shumei, Kurasaki Kellie, Ikeda Sadakatsu, Kurzrock Razelle. Rare tumor clinic: The UCSD Moores Cancer Center experience with a precision therapy approach. JOURNAL OF CLINICAL ONCOLOGY. 2017.05; 35 (15): ( DOI )

  54. Patel Maulik, Ikeda Sadakatsu, Pilat Susan R., Kurzrock Razelle. JAK1 Genomic Alteration Associated With Exceptional Response to Siltuximab in Cutaneous Castleman Disease JAMA DERMATOLOGY. 2017.05; 153 (5): 449-452. ( DOI )

  55. Ikeda Sadakatsu, Lim Jordan S., Kurzrock Razelle. Analysis of tissue and circulating tumor DNA by next-generation sequencing of hepatocellular carcinoma JOURNAL OF CLINICAL ONCOLOGY. 2017.02; 35 (4 S):

  56. Millis Sherri Z., Ikeda Sadakatsu, Reddy Sandeep, Gatalica Zoran, Kurzrock Razelle. Landscape of Phosphatidylinositol-3-Kinase Pathway Alterations Across 19 784 Diverse Solid Tumors JAMA ONCOLOGY. 2016.12; 2 (12): 1565-1573. ( DOI )

  57. Singh Alok R., Joshi Shweta, Burgoyne Adam M., Sicklick Jason K., Ikeda Sadakatsu, Kono Yuko, Garlich Joseph R., Morales Guillermo A., Durden Donald L.. Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma MOLECULAR CANCER THERAPEUTICS. 2016.11; 15 (11): 2553-2562. ( DOI )

  58. Schwaederle Maria, Husain Hatim, Fanta Paul T, Piccioni David E, Kesari Santosh, Schwab Richard B, Patel Sandip P, Harismendy Olivier, Ikeda Megumi, Parker Barbara A, Kurzrock Razelle. Use of Liquid Biopsies in Clinical Oncology: Pilot Experience in 168 Patients. Clin Cancer Res. 2016.11; 22 (22): 5497-5505. ( PubMed, DOI )

  59. 池田 貞勝. プレシジョン・メディスン　ゲノム医療とその先へ 癌患者におけるゲノム配列分析の取り組み 日本癌学会総会記事. 2016.10; 75回 CS4-CS1. ( ichushi )

  60. Ikeda Sadakatsu, Goodman Aaron M., Cohen Philip R., Jensen Taylor J., Ellison Christopher K., Frampton Garrett, Miller Vincent, Patel Sandip P., Kurzrock Razelle. Metastatic basal cell carcinoma with amplification of PD-L1: exceptional response to anti-PD1 therapy NPJ GENOMIC MEDICINE. 2016.10; 1 16037. ( DOI )

  61. Khemlina Galina, Ikeda Sadakatsu, Kurzrock Razelle. Molecular landscape of prostate cancer: Implications for current clinical trials CANCER TREATMENT REVIEWS. 2015.11; 41 (9): 761-766. ( DOI )

  62. Ikeda Sadakatsu, Hansel Donna E., Kurzrock Razelle. Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma CANCER TREATMENT REVIEWS. 2015.09; 41 (8): 699-706. ( DOI )

  63. Millis Sherri Z., Ikeda Sadakatsu, Arguello David, Feldman Rebecca, Maney Robert Todd, Xiu Joanne, Reddy Sandeep K., Kurzrock Razelle. PI3K/PTEN/Akt/mTOR pathway aberrations and co-incidence of hormone receptors and HER2 in 19,784 diverse solid JOURNAL OF CLINICAL ONCOLOGY. 2015.05; 33 (15 S):

  64. Sunshine Sarah B., Dallabrida Susan M., Durand Ellen, Ismail Nesreen S., Bazinet Lauren, Birsner Amy E., Sohn Regina, Ikeda Sadakatsu, Pu William T., Kulke Matthew H., Javaherian Kashi, Zurakowski David, Folkman Judah M., Rupnick Maria. Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012.07; 109 (28): 11306-11311. ( DOI )

  65. Bisping Egbert, Ikeda Sadakatsu, Sedej Miriam, Wakula Paulina, McMullen Julie R., Tarnavski Oleg, Sedej Simon, Izumo Seigo, Pu William T., Pieske Burkert. Transcription Factor GATA4 Is Activated but Not Required for Insulin-like Growth Factor 1 (IGF1)-induced Cardiac Hypertrophy JOURNAL OF BIOLOGICAL CHEMISTRY. 2012.03; 287 (13): 9827-9834. ( DOI )

  66. Zhang Zhiyuan, Wang Hao, Ikeda Sadakatsu, Fahey Frederic, Bielenberg Diane, Smits Patrick, Hauschka Peter V.. Notch3 in Human Breast Cancer Cell Lines Regulates Osteoblast-Cancer Cell Interactions and Osteolytic Bone Metastasis AMERICAN JOURNAL OF PATHOLOGY. 2010.09; 177 (3): 1459-1469. ( DOI )

  67. Ikeda Sadakatsu, Pu William T.. Expression and Function of MicroRNAs in Heart Disease CURRENT DRUG TARGETS. 2010.08; 11 (8): 913-925. ( DOI )

  68. Ikeda Sadakatsu, Pu William T. Expression and function of microRNAs in heart disease. Curr Drug Targets. 2010.08; 11 (8): 913-925. ( PubMed )

  69. Kong Sek Won, Hu Yong Wu, Ho Joshua W. K., Ikeda Sadakatsu, Polster Sean, John Ranjit, Hall Jennifer L., Bisping Egbert, Pieske Burkert, dos Remedios Cristobal G., Pu William T.. Heart Failure-Associated Changes in RNA Splicing of Sarcomere Genes CIRCULATION-CARDIOVASCULAR GENETICS. 2010.04; 3 (2): 138-U72. ( DOI )

  70. Ikeda Sadakatsu, He Aibin, Ma Qing, Pu William T.. The Novel Mechanism of Posttranscriptional Regulation of Calmodulin and Mef2a by MicroRNA-1 CIRCULATION RESEARCH. 2009.09; 105 (7): E33.

  71. Ikeda Sadakatsu, He Aibin, Kong Sek Won, Lu Jun, Bejar Rafael, Bodyak Natalya, Lee Kyu-Ho, Ma Qing, Kang Peter M., Golub Todd R., Pu William T.. MicroRNA-1 Negatively Regulates Expression of the Hypertrophy-Associated Calmodulin and Mef2a Genes MOLECULAR AND CELLULAR BIOLOGY. 2009.04; 29 (8): 2193-2204. ( DOI )

  72. Zhou Bin, Ma Qing, Rajagopal Satish, Wu Sean M., Domian Ibrahim, Rivera-Feliciano Jose, Jiang Dawei, von Gise Alexander, Ikeda Sadakatsu, Chien Kenneth R., Pu William T.. Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart NATURE. 2008.07; 454 (7200): 109-U5. ( DOI )

  73. Ikeda Sadakatsu, Kong Sek Won, Lu Jun, Bisping Egbert, Zhang Hao, Allen Paul D., Golub Todd R., Pieske Burkert, Pu William T.. Altered microRNA expression in human heart disease PHYSIOLOGICAL GENOMICS. 2007.11; 31 (3): 367-373. ( DOI )

  74. Robinson Barbara, Ikeda Sadakatsu, Poutias Dimitri, Kazu Kitahori, Friehs Ingelborg, Eddy Mau-Thek, McGowan Frank, del Nido Pedro. Novel pharmacologic induction of and protection with the endogenous cytoprotective myocardial heat shock protein 70i by the anti-ulcer agent, GGA, is associated with improved ventricular function after global ischemia and a reduction in troponin T release. CIRCULATION. 2007.10; 116 (16): 756.

  75. Ikeda Sadakatsu, Kong Sek Won, Lu Jun, Bisping Egbert, Bodyak Natalya, Lee Kyu-Ho, Ma Qing, Kang Peter M., Pieske Burkert, Allen Paul D., Golub Todd, Pu William T.. Downregulation of cardiomyocyte-enriched micromas contributes to altered gene expression in heart failure CIRCULATION. 2007.10; 116 (16 S): 162.

  76. Bisping Egbert, Ikeda Sadakatsu, Kong Sek Won, Tarnavski Oleg, Bodyak Natalya, McMullen Julie R., Rajagopal Satish, Son Jennifer K., Ma Qing, Springer Zhangli, Kang Peter M., Izumo Seigo, Pu William T.. Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006.09; 103 (39): 14471-14476. ( DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Satoru Aoyama, Ayako Nogami, Sadakatsu Ikeda, Takehiko Mori. Establishment of novel Chimeric Antigen Receptor (CAR) improving the target-cell-specificity.. The 85th Annual Meeting of the Japanese Society of Hematology 2023.10.13

  2. Satoru Aoyama, Takashi Kamatani, Kousuke Tanimoto, Junko Yokobori, Eriko Takamine, Makiko Egawa, Yuki Kato, Susumu Kirimura, Ichiro Ohnishi, Kouichiro Kimura, Takahiro Asakage, Sadakatsu Ikeda. Case report: Myxofibrosarcoma in the head and neck region with rare TP53 aberration in the background of retinoblastoma.. 2023 the Japanese Society of Medical Oncology Annual Meeting 2023.03.17

  3. Satoru Aoyama, Ayako Nogami, Sadakatsu Ikeda, Takehiko Mori. Novel protease-mediated double antigen recognizing Chimeric Antigen Receptor (CAR) enhances the directionality of CAR-T cell activity and improves target cell specificity.. Keystone symposia A4: Emerging Cellular Therapies at the Forefront of Cancer Immunotherapy 2023.01.31

  4. Satoru Aoyama, Ayako Nogami, Sadakatsu Ikeda, Takehiko Mori. Novel protease-mediated double antigen recognizing Chimeric Antigen Receptor (CAR) enhances directionality of CAR-T cell activity and improves target cell specificity.. 64th American Society of Hematology (ASH) annual Meeting and Exposition 2022.12.10

  5. 松原 淳一, 向井 久美, 近藤 知大, 鹿毛 秀宣, 織田 克利, 工藤 亮, 池田 貞勝, 衣斐 寛倫, 室 圭, 林 龍二, 徳留 なほみ, 山本 信之, 武藤 学. 化学療法未施行切除不能進行がんに対する遺伝子パネル検査の有用性を評価する臨床研究. 日本癌治療学会学術集会抄録集 2022.10.01

  6. Inoue Dai, Ikeda Sadakatsu, Namiki Shin. Molecular profiling of pancreatic cancer and application of liquid biopsy to clinical practice　Low detection rate of druggable mutations in CGP using ctDNA in pancreatic cancer(タイトル和訳中). 膵臓 2022.09.01

  7. 松寺 翔太郎, 加納 嘉人, 岡本 健太郎, 鈴木 完, 小嶋 一幸, 三宅 智, 池田 貞勝. がんゲノム医療推進のためのがんプレシジョンメディシンフェローシッププログラム. 日本癌治療学会学術集会抄録集 2021.10.01

  8. Sadakatsu Ikeda. The clinical significance of comprehensive genomic profiling. ESMO Asia2019 2019.11.22 Singapore, Singapore

  9. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性腫瘍のゲノムシーケンス解析(Genomic sequencing in HBP malignancies). 日本消化器病学会雑誌 2019.11.01

  10. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性腫瘍のゲノムシーケンス解析(Genomic sequencing in HBP malignancies). 日本消化器病学会雑誌 2019.11.01

  11. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性腫瘍のゲノムシーケンス解析(Genomic sequencing in HBP malignancies). 日本消化器病学会雑誌 2019.11.01

  12. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性腫瘍のゲノムシーケンス解析(Genomic sequencing in HBP malignancies). 日本消化器病学会雑誌 2019.11.01

  13. Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性腫瘍のゲノムシーケンス解析(Genomic sequencing in HBP malignancies). 日本消化器病学会雑誌 2019.11.01

  14. 高橋 健太, 熊木 裕一, 横堀 潤子, 高嶺 恵里子, 大島 乃里子, 若菜 公雄, 石川 敏昭, 伴 大輔, 工藤 篤, 木村 浩一朗, 中川 剛士, 田邉 稔, 宮坂 尚幸, 三宅 智, 池田 貞勝. がんの診断・治療とLiquid Biopsyの意義　がんゲノム医療におけるLiquid biopsyの可能性　前向き観察研究PROFILE試験の結果から. 日本癌治療学会学術集会抄録集 2019.10.01

  15. 大島 乃里子, 高橋 健太, 中村 玲子, 吉野 育典, 若菜 公雄, 池田 貞勝, 宮坂 尚幸. 当院における婦人科腫瘍のがんゲノム医療. 日本癌治療学会学術集会抄録集 2019.10.01

  16. 齋藤 亜由美, 池田 貞勝, 福田 美佐緒, 安次嶺 宏哉, 宮地 康僚, 池 成基, 大山 優. 当院におけるがんゲノム医療の診療経験. 日本癌治療学会学術集会抄録集 2019.10.01

  17. 武藤 学, 金井 雅史, 鶴山 竜昭, 松本 繁巳, 豊岡 伸一, 秋田 弘俊, 松原 久裕, 西原 広史, 末岡 榮三朗, 池田 貞勝. バイオバンキングが切り拓く新しいがん研究　わが国におけるクリニカルバイオバンクネットワークの構築(Innovative cancer research based on biobanking　Clinical biobank network in Japan). 日本癌学会総会記事 2019.09.01

  18. 武藤 学, 金井 雅史, 鶴山 竜昭, 松本 繁巳, 豊岡 伸一, 秋田 弘俊, 松原 久裕, 西原 広史, 末岡 榮三朗, 池田 貞勝. バイオバンキングが切り拓く新しいがん研究　わが国におけるクリニカルバイオバンクネットワークの構築(Innovative cancer research based on biobanking　Clinical biobank network in Japan). 日本癌学会総会記事 2019.09.01

  19. 武藤 学, 金井 雅史, 鶴山 竜昭, 松本 繁巳, 豊岡 伸一, 秋田 弘俊, 松原 久裕, 西原 広史, 末岡 榮三朗, 池田 貞勝. バイオバンキングが切り拓く新しいがん研究　わが国におけるクリニカルバイオバンクネットワークの構築(Innovative cancer research based on biobanking　Clinical biobank network in Japan). 日本癌学会総会記事 2019.09.01

  20. 武藤 学, 金井 雅史, 鶴山 竜昭, 松本 繁巳, 豊岡 伸一, 秋田 弘俊, 松原 久裕, 西原 広史, 末岡 榮三朗, 池田 貞勝. バイオバンキングが切り拓く新しいがん研究　わが国におけるクリニカルバイオバンクネットワークの構築(Innovative cancer research based on biobanking　Clinical biobank network in Japan). 日本癌学会総会記事 2019.09.01

  21. 武藤 学, 金井 雅史, 鶴山 竜昭, 松本 繁巳, 豊岡 伸一, 秋田 弘俊, 松原 久裕, 西原 広史, 末岡 榮三朗, 池田 貞勝. バイオバンキングが切り拓く新しいがん研究　わが国におけるクリニカルバイオバンクネットワークの構築(Innovative cancer research based on biobanking　Clinical biobank network in Japan). 日本癌学会総会記事 2019.09.01

  22. 池田貞勝、他. Comparison of variant detection power between small and medium size panel in clinical sequencing for Japanese patients. 第17回日本臨床腫瘍学会学術集会 2019.07.19

  23. 池田貞勝. Novel Treatment Strategies using Liquid Biopsy. 第27回日本乳癌学会学術総会 2019.07.11

  24. Yuichi Kumaki, Sadakatsu Ikeda, Thereasa A. Rich, Jing Zhao, Takayuki Yoshino, Byoung Chul Cho, Nir Peled, Ji-Youn Han, Yukimasa Shiotsu, Aleksandra Franovic, Victoria M. Raymond, Razelle Kurzrock, Richard B. Lanman, Jeeyun Lee, Tony S. K. Mok. Comprehensive genomic profiling of circulating cell-free DNA (cfDNA) distinguishes focal amplification (amp) from aneuploidy among MET amps in diverse advanced cancer types. 2019 ASCO annual meeting 2019.06.01 Chicago, USA

  25. Kumaki Y, Ikeda S, Rich TA, Shiotsu Y, Franovic A, Raymond VM, Kurzrock R, Lanman RB, Lee J, Mok TSK. Circulating cell-free DNA molecular profiling among East Asian patients reveals activating MET alterations are common in diverse advanced cancer types. ESMO Asia 2018 Congress 2018.11.24

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