Personnel Information

写真a

YUI SHIRO


Job title

Junior Associate Professor

Birth date

1977

Mail Address

syuiarm@tmd.ac.jp

Graduating School 【 display / non-display

  • Keio University, Faculty of Medicine, 2002.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Medicine, Doctor's Course, 2011.03, Completed

Campus Career 【 display / non-display

  • 2017.10
    -
    2019.12
    Tokyo Medical and Dental University, Institute of Research, Division of Advanced Research, Center for Stem Cell and Regenerative Medicine, Assistant Professor
  • 2020.01
    -
    Now
    Tokyo Medical and Dental University, Institute of Research, Division of Advanced Research, Center for Stem Cell and Regenerative Medicine, Junior Associate Professor

External Career 【 display / non-display

  • 2017.10
    -
    Now
    , Project Assistant Professor

Research Areas 【 display / non-display

  • Gastroenterology

Qualification Acquired 【 display / non-display

  • Doctor

 

Published Papers & Misc 【 display / non-display

  • Sho Anzai, Ami Kawamoto, Sayaka Nagata, Junichi Takahashi, Mao Kawai, Reiko Kuno, Sakurako Kobayashi, Satoshi Watanabe, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Shigeru Oshima, Mamoru Watanabe, Ryuichi Okamoto. TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells. Biochem. Biophys. Res. Commun.. 2020.04; 524 (3): 533-541. ( PubMed, DOI )

  • Ryuichi Okamoto, Hiromichi Shimizu, Kohei Suzuki, Ami Kawamoto, Junichi Takahashi, Mao Kawai, Sayaka Nagata, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Mamoru Watanabe. Organoid-based regenerative medicine for inflammatory bowel disease. Regen Ther. 2020.03; 13 1-6. ( PubMed, DOI )

  • Jordi Guiu, Edouard Hannezo, Shiro Yui, Samuel Demharter, Svetlana Ulyanchenko, Martti Maimets, Anne Jørgensen, Signe Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H Pers, Konstantin Khodosevich, Benjamin D Simons, Kim B Jensen. Tracing the origin of adult intestinal stem cells. Nature. 2019.06; 570 (7759): 107-111. ( PubMed, DOI )

  • Ami Kawamoto, Sayaka Nagata, Sho Anzai, Junichi Takahashi, Mao Kawai, Minami Hama, Daichi Nogawa, Kohei Yamamoto, Reiko Kuno, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Shiro Yui, Shigeru Ohshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Masanobu Kitagawa, Ryuichi Okamoto, Mamoru Watanabe. Ubiquitin D is up-regulated by synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients. J Crohns Colitis. 2018.11; ( PubMed, DOI )

  • Kohei Suzuki, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Toru Nakata, Satoru Fujii, Fumiaki Ishibashi, Ami Kawamoto, Sho Anzai, Reiko Kuno, Konomi Kuwabara, Junichi Takahashi, Minami Hama, Sayaka Nagata, Yui Hiraguri, Kento Takenaka, Shiro Yui, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties. J. Gastroenterol.. 2018.09; 53 (9): 1035-1047. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Sakurako Kobayashi, Satoshi Watanabe, Yosuke Yoneyama, Kousuke Tanimoto, Ryu Nishimura, Sayaka Nagata, Masami Inoue, Kouhei Suzuki, Sei Kakinuma, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Takanori Takebe, Shiro Yui. Conceptual basis of lineage shift between intestinal epithelium and hepatocytes. Keystone Symposia, Tissue Organoids as Models of Host Physiology and Pathophysiology of Disease 2020.01.22 Vancouver(Canada)

  • Shiro Yui. Regenerative medicine in treatment of IBD. APDW 2019 2019.12.12 Kolkata (India)

  • Shiro Yui, Mamoru Watanabe. Stem Cells in Gut, Who are They and How They Work, What Can We Count on Them. AOCC2019 2019.06.16 Taipei(Taiwan)

  • Kawai M, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Yui S, Okamoto R, Watanabe M. Functional analysis of isoflavones using patient-derived intestinal organoids. AOCC2019 2019.06.14 Taipei(Taiwan)

  • Ryuichi Okamoto, Mao Kawai, Minami Hama, Sayaka Nagata, Ami Kawamoto, Kohei Suzuki, Hiromichi Shimizu, Sho Anzai, Junichi Takahashi, Reiko Kuno, Sayaka Takeoka, Yui Hiraguri, Shiro Yui, Mamoru Watanabe. 【The 6th JSGE International Topic Conference Lifestyle-related Diseases in Gastroenterology】Gastrointestinal tract(role of gut microbiome and diet). 第105回 日本消化器病学会総会 2019.05.10 ホテル日航金沢(石川県金沢市)

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