Personnel Information

写真a

KAWAMOTO Ami


Job title

Assistant Professor
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Campus Career 【 display / non-display 】

  • 2015.04
    -
    2019.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Systemic Organ Regulation， Gastroenterology and Hepatology， Graduate Student
  • 2019.10
    　
    　
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Internal Medicine， Gastroenterology and Hepatology， Project Assistant Professor
  • 2019.11
    -
    2021.09
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Internal Medicine， Gastroenterology and Hepatology， Project Assistant Professor
  • 2021.10
    -
    2023.03
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Medicine， Department of Internal Medicine， Gastroenterology and Hepatology， Project Assistant Professor
  • 2023.04
    -
    Now
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Medicine， Department of Specialized Medical Care， Endoscopy， Assistant Professor
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Published Papers & Misc 【 display / non-display 】

  1. Sho Anzai, Ami Kawamoto, Sayaka Nagata, Junichi Takahashi, Mao Kawai, Reiko Kuno, Sakurako Kobayashi, Satoshi Watanabe, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Shigeru Oshima, Mamoru Watanabe, Ryuichi Okamoto. TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells. Biochem. Biophys. Res. Commun.. 2020.04; 524 (3): 533-541. ( PubMed, DOI )

  2. Ryuichi Okamoto, Hiromichi Shimizu, Kohei Suzuki, Ami Kawamoto, Junichi Takahashi, Mao Kawai, Sayaka Nagata, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Mamoru Watanabe. Organoid-based regenerative medicine for inflammatory bowel disease. Regen Ther. 2020.03; 13 1-6. ( PubMed, DOI )

  3. Hiromune Katsuda, Masanori Kobayashi, Go Ito, Ami Kawamoto, Susumu Krimura, Hiroyuki Sato, Akihiro Hirakawa, Keiichi Akahoshi, Atsushi Kudo, Kazuo Ohtsuka, Ryuichi Okamoto. Evaluating endoscopic ultrasound-guided tissue acquisition for diagnosis of small pancreatic neuroendocrine neoplasms. Endosc Int Open. 2024.11; 12 (11): E1379-E1385. ( PubMed, DOI )

  4. Hiromichi Shimizu, Yuko Aonuma, Shuji Hibiya, Ami Kawamoto, Kento Takenaka, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Ryuichi Okamoto. Long-term efficacy and safety of tofacitinib in patients with ulcerative colitis: 3-year results from a real-world study. Intest Res. 2024.07; 22 (3): 369-377. ( PubMed, DOI )

  5. Makoto Naganuma, Naohiro Nakamura, Reiko Kunisaki, Katsuyoshi Matsuoka, Shojiro Yamamoto, Ami Kawamoto, Daisuke Saito, Taku Kobayashi, Kosaku Nanki, Kazuyuki Narimatsu, Hisashi Shiga, Motohiro Esaki, Shinichiro Yoshioka, Shingo Kato, Masayuki Saruta, Shinji Tanaka, Eriko Yasutomi, Kaoru Yokoyama, Kei Moriya, Yoshikazu Tsuzuki, Makoto Ooi, Mikihiro Fujiya, Atsushi Nakazawa, Tomohisa Takagi, Teppei Omori, Toshiyuki Tahara, Tadakazu Hisamatsu & The Japanese UC Study Group . Medical treatment selection and outcomes for hospitalized patients with severe ulcerative colitis as defined by the Japanese criteria. J Gastroenterol. 2024.04; 59 (4): 302-314. ( PubMed, DOI )

  6. Ami Kawamoto, Kento Takenaka, Shuji Hibiya, Yoshio Kitazume, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Kazuo Ohtsuka, Ryuichi Okamoto. Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn's disease activity confirmed by balloon-assisted enteroscopy. Intest Res. 2024.01; 22 (1): 65-74. ( PubMed, DOI )

  7. Nanako Hashido, Masanori Kobayashi, Ami Kawamoto, Suguru Mabuchi, Hiromune Katsuda, Kazuo Ohtsuka, Yasuhiro Asahina, Masayoshi Hashimoto, Ryuichi Okamoto. Sphincter of Oddi dysfunction that could not be diagnosed with Rome IV: a case report. Clin J Gastroenterol. 2023.12; 16 (6): 913-918. ( PubMed, DOI )

  8. Makoto Naganuma, Taku Kobayashi, Reiko Kunisaki, Katsuyoshi Matsuoka, Shojiro Yamamoto, Ami Kawamoto, Daisuke Saito, Kosaku Nanki, Kazuyuki Narimatsu, Hisashi Shiga, Motohiro Esaki, Shinichiro Yoshioka, Shingo Kato, Masayuki Saruta, Shinji Tanaka, Eriko Yasutomi, Kaoru Yokoyama, Kei Moriya, Yoshikazu Tsuzuki, Makoto Ooi, Mikihiro Fujiya, Atsushi Nakazawa, Takayuki Abe, Tadakazu Hisamatsu, . Real-world efficacy and safety of advanced therapies in hospitalized patients with ulcerative colitis. J Gastroenterol. 2023.12; 58 (12): 1198-1210. ( PubMed, DOI )

  9. Shuji Hibiya, Takashi Fujii, Toshimitsu Fujii, Shinji Suzuki, Mayumi Kondo, Shinya Ooka, Yohei Furumoto, Seishin Azuma, Kei Tanaka, Hitoshi Kurata, Shohei Tanaka, Masayuki Kurosaki, Kazuyoshi Nagayama, Fumihiko Kusano, Yasuhiro Iizuka, Takahiro Kawamura, Hidekazu Ikemiyagi, Shinya Sakita, Tsunehito Yauchi, Hideki Watanabe, Ami Kawamoto, Yusuke Matsuyama, Kazuo Ohtsuka, Ryuichi Okamoto. COVID-19 severity is associated with the risk of gastrointestinal bleeding. BMJ Open Gastroenterol. 2023.11; 10 (1): ( PubMed, DOI )

  10. Kento Takenaka, Ami Kawamoto, Yoshio Kitazume, Toshimitsu Fujii, Yumi Udagawa, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Transmural Remission Characterized by High Biologic Concentrations Demonstrates Better Prognosis in Crohn's Disease. J Crohns Colitis. 2023.06; 17 (6): 855-862. ( PubMed, DOI )

  11. Kento Takenaka, Yoshio Kitazume, Ami Kawamoto, Toshimitsu Fujii, Yumi Udagawa, Ryosuke Wanatabe, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Hiroyuki Sato, Akihiro Hirakawa, Mamoru Watanabe, Ryuichi Okamoto. Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease. Am J Gastroenterol. 2023.06; 118 (6): 1028-1035. ( PubMed, DOI )

  12. Fujiwara S, Kawamoto A, Motobayashi M, Hibiya S, Takenaka K, Shimizu H, Saito E, Fujii T, Nagahori M, Kawata D, Umezawa N, Hosoya T, Yasuda S, Ohtsuka K, Okamoto R. Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab. DEN open. 2023.04; 3 (1): e196. ( PubMed, DOI )

  13. Eiko Saito, Kazuo Ohtsuka, Ami Kawamoto, Toshimitsu Fujii, Kento Takenaka, Shuji Hibiya, Hiromichi Shimizu, Masakazu Nagahori, Shohei Tomii, Ryuichi Okamoto. A case of venous stasis colitis possibly caused by eplerenone. Clin J Gastroenterol. 2023.02; 16 (1): 69-72. ( PubMed, DOI )

  14. Ami Kawamoto, Toshimitsu Fujii, Ryuji Mitani, Yasuhiro Suzuki, Tsunehito Yauchi, Ryuichi Okamoto. Serum Levels of Infliximab Biosimilar in a Child Delivered From a Mother Treated for Ulcerative Colitis.( Online ahead of print.) Inflamm Bowel Dis. 2022.06; ( PubMed, DOI )

  15. Shuji Hibiya, Kazuo Ohtsuka, Kento Takenaka, Ami Kawamoto, Yusuke Matsuyama, Yumi Udagawa, Maiko Motobayashi, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Ryuichi Okamoto, Mamoru Watanabe. Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease. BMC Gastroenterol. 2022.05; 22 (1): 218. ( PubMed, DOI )

  16. Ami Kawamoto, Kento Takenaka, Ryuichi Okamoto, Mamoru Watanabe, Kazuo Ohtsuka. Systematic review of artificial intelligence-based image diagnosis for inflammatory bowel disease. Dig Endosc. 2022.04; ( PubMed, DOI )

  17. Hiromichi Shimizu, Toshimitsu Fujii, Kenji Kinoshita, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus. BMC Gastroenterol. 2021.12; 21 (1): 494. ( PubMed, DOI )

  18. Kento Takenaka, Ami Kawamoto, Kazuo Ohtsuka. Editorial: higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease-authors' reply. Aliment Pharmacol Ther. 2021.10; 54 (8): 1087. ( PubMed, DOI )

  19. A Kawamoto, K Takenaka, S Hibiya, K Ohtsuka, R Okamoto, M Watanabe. Serum Leucine-Rich α 2 Glycoprotein: A Novel Biomarker For Small Bowel Mucosal Activity in Crohn's Disease Clin Gastroenterol Hepatol. 2021.06; ( PubMed, DOI )

  20. Reiko Kuno, Go Ito, Ami Kawamoto, Yui Hiraguri, Hady Yuki Sugihara, Sayaka Takeoka, Sayaka Nagata, Junichi Takahashi, Mao Tsuchiya, Sho Anzai, Tomohiro Mizutani, Hiromichi Shimizu, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Mamoru Watanabe, Ryuichi Okamoto. Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients. Biochem Biophys Rep. 2021.03; 25 100906. ( PubMed, DOI )

  21. Shuji Hibiya, Yusuke Matsuyama, Toshimitsu Fujii, Chiaki Maeyashiki, Eiko Saito, Kimiko Ito, Hiromichi Shimizu, Ami Kawamoto, Maiko Motobayashi, Kento Takenaka, Masakazu Nagahori, Masayuki Kurosaki, Tsunehito Yauchi, Kazuo Ohtsuka, Takeo Fujiwara, Ryuichi Okamoto, Mamoru Watanabe. 5-aminosalicylate-intolerant patients are at increased risk of colectomy for ulcerative colitis. Aliment Pharmacol Ther. 2021.01; 53 (1): 103-113. ( PubMed, DOI )

  22. Ami Kawamoto, Sayaka Nagata, Sho Anzai, Junichi Takahashi, Mao Kawai, Minami Hama, Daichi Nogawa, Kouhei Yamamoto, Reiko Kuno, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Masanobu Kitagawa, Ryuichi Okamoto, Mamoru Watanabe. Ubiquitin D is upregulated by synergy of notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients. J Crohns Colitis. 2019.03; 13 (4): 495-509. ( PubMed, DOI )

  23. Kohei Suzuki, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Toru Nakata, Satoru Fujii, Fumiaki Ishibashi, Ami Kawamoto, Sho Anzai, Reiko Kuno, Konomi Kuwabara, Junichi Takahashi, Minami Hama, Sayaka Nagata, Yui Hiraguri, Kento Takenaka, Shiro Yui, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties. J. Gastroenterol.. 2018.09; 53 (9): 1035-1047. ( PubMed, DOI )

  24. Fumiaki Ishibashi, Hiromichi Shimizu, Toru Nakata, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Sho Anzai, Reiko Kuno, Sayaka Nagata, Go Ito, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, Ryuichi Okamoto. Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium. Stem Cell Reports. 2018.01; 10 (1): 27-42. ( PubMed, DOI )

  25. Toru Nakata, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Reiko Kuno, Sho Anzai, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe, Ryuichi Okamoto. Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine. Data Brief. 2017.02; 10 551-556. ( PubMed, DOI )

  26. Toru Nakata, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Reiko Kuno, Sho Anzai, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe, Ryuichi Okamoto. Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors. Biochem. Biophys. Res. Commun. 2017.01; 482 (4): 1296-1303. ( PubMed, DOI )

  27. Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Tatsuro Murano, Go Ito, Hiromichi Shimizu, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Akihiro Araki, Kazuo Ohtsuka, Ryuichi Okamoto, Mamoru Watanabe. PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells. Sci Rep. 2016.11; 6 36795. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Keisuke Hata, Won Moon, Ami Kawamoto. JSIBD-KASID Joint Symposium_司会. The 15th Annual Meeting of Japanese Society for Inflammatory Bowel Disease 2024.11.15 Tokyo_Japan

  2. Ami Kawamoto, Toshimitsu Fujii, Ryuichi Okamoto. Serum leucine-rich alpha-2 glycoprotein is an accurate marker for endoscopic and histological healing in ulcerative colitis. JDDW2024 2024.11.01 Kobe_Japan

  3. Ami Kawamoto, Kento Takenaka, Ryuichi Okamoto. Efficacy of biomarkers in predicting prognosis of Crohn’s disease patients with small bowel disease. 第107回日本消化器内視鏡学会総会 2024.05.30 国際館パミール

  4. T. Fujii , S. Hibiya , H. Shimizu , A. Kawamoto , K. Takenaka , E. Saito , M. Nagahori , K. Ohtsuka , R. Okamoto. DUAL THERAPY WITH CAROTEGRAST (AJM300: ORAL α4 INTEGRIN ANTAGONIST) AND BIOLOGICS FOR REFRACTORY ULCERATIVE COLITIS. UEGW2023 2023.10.15 Copenhagen_Denmark

  5. A. Kawamoto, K. Takenaka, S. Hibiya, Y. Kitazume, K. Ito, H. Shimizu, T. Fujii, E. Saito, K. Ohtsuka, R. Okamoto. COMBINING LEUCINE-RICH ALPHA-2 GLYCOPROTEIN AND FAECAL BIOMARKERS FOR ACCURATE MONITORING OF SMALL BOWEL ACTIVITY IN CROHN’S DISEASE. UEGW2023 2023.10.14 Copenhagen_Denmark

  6. Ami Kawamoto. Novel Biomarkers for Small Intestinal Crohn’s Disease. UEG Week 2022 2022.10.11

  7. 土屋輝一郎、長堀正和、日比谷秀爾、竹中健人、河本亜美、清水寛路、藤井俊光、齊藤詠子、大塚和朗、渡辺　守、岡本隆一 . 【誌面発表】COVID-19蔓延下におけるスマートデバイスを用いたIBD病診連携に関する研究. 厚生労働科学研究費 難治性疾患政策研究事業 「難治性炎症性腸管障害に関する調査研究」令和3年度 第1回総会 2021.07.15 Web開催

  8. Kawai M, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Yui S, Okamoto R, Watanabe M. Functional analysis of isoflavones using patient-derived intestinal organoids. AOCC2019 2019.06.14 Taipei（Taiwan）

  9. Ryuichi Okamoto, Mao Kawai, Minami Hama, Sayaka Nagata, Ami Kawamoto, Kohei Suzuki, Hiromichi Shimizu, Sho Anzai, Junichi Takahashi, Reiko Kuno, Sayaka Takeoka, Yui Hiraguri, Shiro Yui, Mamoru Watanabe. 【The 6th JSGE International Topic Conference　Lifestyle-related Diseases in Gastroenterology】Gastrointestinal tract（role of gut microbiome and diet）. 第105回 日本消化器病学会総会 2019.05.10 ホテル日航金沢（石川県金沢市）

  10. Kawamoto A, Nagata S, Anzai S, Takahashi J, Kawai M, Hama M, Nogawa D, Yamamoto K, Kuno R, Suzuki K, Shimizu H, Hiraguri Y, Yui S, Oshima S, Tsuchiya K, Nakamura T, Ohtsuka K, Kitagawa M, Okamoto R, Watanabe M. Synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients leads to up-regulation of UBD, a ubiquitin-like protein. ECCO2019 2019.03.08 Copenhagen（Denmark）

  11. Suzuki K, Shimizu H, Kawai M, Takahashi J, Anzai S, Kawamoto A, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M . UC-related and segment-specific properties of patientderived colonic organoids. ECCO2019 2019.03.07 Copenhagen（Denmark）

  12. Ishibashi F, Kuwabara K, Kawamoto A, Anzai S, Takahashi J, Nagata S, Shimizu H, Yui S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R. Ectopic expression of reg3a in the mice distal Colon is mediated by interactions between notch and Il-22 signaling pathways, and promotes tissue repair By the augmentation of EGFR signaling. UEGW 2018 2018.10.22 Vienna（Austria）

  13. Kuwabara K, Ishibashi F, Kawamoto A, Anzai S, Takahashi J, Nagata S, Shimizu H, Yui S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R. Long-lived secretory cells residing in the Mouse proximal colon serve as reserve stem cells Under DNA damage-induced mucosal injury. UEGW 2018 2018.10.22 Vienna（Austria）

  14. Suzuki K, Murano T, Hiraguri Y, Takahashi J, Shimizu H,Anzai S, Kuwabara K, Kawamoto A, Ishibashi F, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R... Crohn’s disease patient-derived small intestinal organoids reveal disease-status related modification of stem cell properties.. 5th TERMIS World Congress 2018 2018.09.06 Kyoto（JAPAN）

  15. Ishibashi F, Shimizu H, Kawamoto A, Suzuki K, Anzai S, Kuwabara K, Takahashi J, Nagata S, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R. Mouse colonic secretory cells de-differentiate into intestinal stem cells and promote mucosal repair through activation of NF-KB signalin. ISSCR2018 2018.06.20 Melbourne

  16. Suzuki K, Kuwabara K, Takahashi J, Anzai S, Kuno R, Kawamoto A, Ishibashi F, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M.. Single-cell level analysis of organoids derived from CD patients reveals disease-status related modifications of small intestinal stem cells. DDW2018 2018.06.04 Washington D.C (USA）

  17. F. Ishibashi H. Shimizu A. Kawamoto G. Ito T. Nakata S. Fujii K. Suzuki R. Kuno S. Anzai K. Kuwabara M. Kawai J. Takahashi M. Hama S. Nagata K. Tsuchiya T. Nakamura R. Okamoto M. Watanabe. Reprogrammed Atoh1+ intestinal epithelial cells contribute to regenerate damaged colonic mucosa in DSS-induced colitis. UEGW2017 (欧州消化器病学会週間2017） 2017.11.01 Barcelona(Spain)

  18. Kawamoto A, Ito G, Nakata T, Fujii S, Suzuki K, Ishibashi F, Shimizu H, Nagata S, Anzai S, Kuno R, Kuwabara K, Kawai M, Takahashi J, Hama M, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M. The ubiquitin-like protein ubiquitin d is up-regulated by synergy of notch and pro-inflammatory cytokines in the inflamed intestinal epithelia of ibd patients.. UEGW2017 2017.11.01 Barcelona(Spain)

  19. Kawamoto A, Ito G, Nakata T, Fujii S, Suzuki K, Ishibashi F, Shimizu H, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M. Synergy of Notch signaling and pro-inflammatory cytokines leads to up-regulation of UBD in the inflamed intestinal epithelia of IBD patients. The 5th Annual Meeting of Asian Organization for Crohn's and Colitis 2017.06.16 Seoul (Korea)

  20. Ishibashi F, Shimizu H, Nakata T, Fujii S, Suzuki K, Kawamoto A, Anzai S, Kuno R, Nagata S, Ito G, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M. Lineage tracing reveals contribution of atoh1+ cell-derived stem cells in the homeostasis, repair, and carcinogenesis of the intestinal epithelium. DDW2017 2017.05.09 Chicago(USA)

  21. Kawamoto A, Nakata T, Fujii S, Suzuki K, Ishibashi F, Shimizu H, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M. Notch signaling and TNF-α synergistically up-regulate stem cell-specific genes, OLFM4 and UBD, in the inflamed intestinal epithelia of IBD patients. 2016 Advances in Inflammatory Bowel Diseases, Crohn’s & Colitis Foundation of America's Clinical & Research Conference (CCFA) 2016.12.10 Orlando, Florida

  22. Kawamoto A, Ito G, Nakata T, Fujii S, Suzuki K, Ishibashi F, Shimizu H, Tsuchiya K, Nakamura T, Okamoto R, Watanabe M. OLFM4 and UBD are up-regulated in the inflamed intestinal epithelia of IBD patients by synergy of Notch signaling and TNF-α. AOCC2016 2016.07.07 Kyoto International Conference Center, Kyoto（JAPAN）

  23. Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Go Ito, Hiromichi Shimizu, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Ryuichi Okamoto, Mamoru Watanabe. In Vitro organoid model reveals PGF2 as a Robust Mediator of chloride & water secretion bt human intestinal epithelial cells. DDW2016 2016.05.23 San Diego（USA）

  24. Toru Nakata, Go Ito, Hiromichi Shimizu, Satoru Fujii, Kohei Suzuki, Fumiaki Ishibashi, Ami Kawamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Ryuichi Okamoto, Mamoru Watanabe. Jagged1 is indispensable for the maintenance of tumor stem cell niche in APC-Deficient intestinal adenomas. DDW2016 2016.05.22 San Diego（USA）

  25. Kohei Suzuki, Satoru Fujii, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Go Ito, Hiromichi Shimizu, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Otsuka, Ryuichi Okamoto, Mamoru Watanabe. Single-cell level analysis reveals hoterogeneous expression of stem-cell specific genes in human small intestinal organoids. DDW2016 2016.05.21 San Diego（USA）

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